BookKensal E. van Holde, Jordanka Zlatanova.
Summary: The Evolution of Molecular Biology: The Search for the Secrets of Life provides the historical knowledge behind techniques founded in molecular biology, also presenting an appreciation of how, and by whom, these discoveries were made. It deals with the evolution of intellectual concepts in the context of active research in an approachable language that accommodates readers from a variety of backgrounds. Each chapter contains a prologue and epilogue to create continuity and provide a complete framework of molecular biology. This foundational work also functions as a historical and conceptual supplement to many related courses in biochemistry, biology, chemistry, genetics and history of science. In addition, the book demonstrates how the roots of discovery and advances-and an individual's own research-have grown out of the history of the field, presenting a more complete understanding and context for scientific discovery.
Contents:
Beginnings
The Origins of Biochemistry
The Chemical Structure of Proteins
Proteins in Three Dimensions
The Origins of Genetics
Nucleic Acids
The Great Synthesis
How DNA is Replicated
The Central Dogma
The Genetic Code
Gene to Protein: The Whole Path
Eukaryotes Pose New Problems
Development and Differentiation
Recombinant DNA: The Next Revolution
Understanding Whole Genomes: Creating New Paradigms
Whole Genomes and Evolution
Practical Applications of Recombinant DNA Technologies
Appendix: Nobel Prize Laureates That Have Contributed to the Development of Molecular Biology.