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  • Book
    Sankhavaram R. Panini.
    Contents:
    Nutrition & digestion
    Carbohydrates
    Lipids
    Amino acids & proteins
    Biochemical reactions & enzymes
    Membranes and transport
    Cell signaling
    Principles of cellular respiration
    Glycolysis and the metabolism of Pyruvate and Acetyl CoA
    Tricarboxylic acid cycle
    Oxidative phosphorylation and the mitochondria
    Carbohydrate metabolism
    Fatty acid metabolism
    Cholesterol and steroid metabolism
    Protein and amino acid metabolism
    Nucleotide and heme metabolism
    Replication
    Transcription
    Translation
    Cell cycle and cancer
    Biotechniques.
    Digital Access Thieme MedOne Education 2013
  • Article
    Bonura T, Smith KC.
    Int J Radiat Biol Relat Stud Phys Chem Med. 1977 Nov;32(5):457-64.
    Escherichia coli C cells, unifilarly substituted with 5-bromouracil (BrUra) were 2-25 times as sensitive as unsubstituted cells to killing by gamma-irradiation under aerobic conditions. The yield of DNA double-strand breaks in BrUra-substituted cells was increased by a factor only 1-55, suggesting that other lesions also contribute to cell-killing. Alkaline sucrose density gradient analysis of the 3H-thymine labelled DNA strand showed there was less repair of gamma-ray-induced single-strand breaks when BrUra was in the complementary strand. Since there are more of these unrepaired breaks than can be accounted for by BrUra-induced DNA double-strand breakage, some fraction of the lethal events in BrUra-substituted E. coli cells may be unrepaired DNA single-strand breaks.
    Digital Access Access Options