BookMagdy M. Khalil, editor.
Summary: This book offers a wide-ranging and up-to-date overview of the basic science underlying PET and its preclinical and clinical applications in modern medicine. In addition, it provides the reader with a sound understanding of the scientific principles and use of PET in routine practice and biomedical imaging research. The opening sections address the fundamental physics, radiation safety, CT scanning dosimetry, and dosimetry of PET radiotracers, chemistry and regulation of PET radiopharmaceuticals, with information on labeling strategies, tracer quality control, and regulation of radiopharmaceutical production in Europe and the United States. PET physics and instrumentation are then discussed, covering the basic principles of PET and PET scanning systems, hybrid PET/CT and PET/MR imaging, system calibration, acceptance testing, and quality control. Subsequent sections focus on image reconstruction, processing, and quantitation in PET and hybrid PET and on imaging artifacts and correction techniques, with particular attention to partial volume correction and motion artifacts. The book closes by examining clinical applications of PET and hybrid PET and their physiological and/or molecular basis in conjunction with technical foundations in the disciplines of oncology, cardiology and neurology, PET in pediatric malignancy and its role in radiotherapy treatment planning. Basic Science of PET Imaging will meet the needs of nuclear medicine practitioners, other radiology specialists, and trainees in these fields.
Contents:
History
Basics and Radiation safety of PET Imaging
Chemistry of PET radiopharmaceuticals: labelling strategies
PET radiopharmaceuticals in clinical and research domains
Quality Control of PET radiopharmaceuticals
Physiologic and Molecular basis of PET in Cancer imaging
Basics and new developments of Cardiac PET imaging
PET in preclinical arena: Instrumentation and applications
Radiation Dosimetry of PET imaging
Physics and instrumentation of PET and hybrid PET Imaging: focus on PET/CT
Hybrid PET/MR Imaging: Technologic advances and clinical applications
Quality control and quality assurance of PET Scanners
Image quantification in PET Imaging
Image processing and data analysis of PET and hybrid PET Imaging
Partial volume correction in PET imaging
Compartmental modeling of PET Kinetics
Motion artefacts and correction techniques in PET/CT
Role of PET/CT in radiotherapy treatment planning.