BookHiroyuki Nakamura, Kazutetsu Aoshiba, editors.
Summary: This book considers chronic obstructive pulmonary disease (COPD) not as a simple inflammation of the lung but as a systemic inflammatory disease. Beginning with epidemiological studies, etiology, diagnosis and treatment, it elaborates further, illustrating some comorbidities and associations with other respiratory diseases. As such it provides numerous improved and more comprehensive treatment methods, including drug therapies as well as some non-drug therapies. There are also chapters describing the pathogenesis, genetic abnormalities and newly discovered pathogenetic mechanisms that are expected to be studied further in the future. Edited and written by pioneering researchers, each chapter summarizes the latest trends, describes future prospects and explores the unresolved and critical questions. Chronic Obstructive Pulmonary Disease - A Systemic Inflammatory Disease is a valuable resource to beginning researchers, physicians engaged in clinical practice, supervisors, and basic researchers whose work includes COPD.
Contents:
Part I Definition and Epidemiology
1. Definition of COPD
2. Epidemiology of COPD
Part II Genetic Predisposition and Pathogenic Mechanisms
3. Genetic predisposition to COPD
4. Pathogenesis of COPD--Persistence of airway inflammation
5. Pathogenesis of COPD 3- Oxidative stress
6. Pathogenesis of COPD 4
Part III Comorbidities
7. Pathogenesis of comorbidities in COPD
8. Assessment of inflammation in COPD
Part IV Management and Treatment
9. Exercise therapy for COPD
10. Nutritional therapy for COPD
11. Home oxygen therapy for COPD
12. Bronchodilators for COPD
13. Inhaled corticosteroids for COPD
14. New anti-inflammatory drugs for COPD
15. Exacerbation of COPD
Part V Associations with other Respiratory Diseases
16. Asthma-COPD overlap syndrome (ACOS)
17.Combined pulmonary fibrosis and emphysema (CPFE)
18. Association of COPD and lung cancer.