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- Videoa WordWise production ; director, Karen van Vuuren ; producers, Karen van Vuuren, Francesca Nicosia.Summary: Michael Miller, a retired surgeon at the end-stage of pancreatic cancer, decides to stop eating and drinking to achieve a more natural death. Medical ethicists and hospice staff discuss issues with patients' rights.PrintLocationVersionCall NumberItems
- Videoa WordWise production ; director, Karen van Vuuren ; producers, Karen van Vuuren, Francesca Nicosia.Summary: Michael Miller, a retired surgeon at the end-stage of pancreatic cancer, decides to stop eating and drinking to achieve a more natural death. Medical ethicists and hospice staff discuss issues with patients' rights.PrintLocationVersionCall NumberItems
- ArticleBrutel de la Rivière A, Verhoef-Karssen PR, von dem Borne AE, Engelfriet CP.Scand J Immunol. 1977;6(4):349-56.In view of the importance of the species of animals used for the preparation of specific heteroantisera against human blood cells, comparative immunization experiments were carried out in goats, rabbit, chickens, guinea pigs, and rats, using lysates of leukocytes, granulocytes, lymphocytes, monocytes, and thrombocytes. The antisera obtained were tested by the indirect immunofluorescence technique. The strongest antisera were obtained in goats, but these antisera required extensive absorptions to make them specific for the immunizing cell, whereas rabbit antisera needed only few absorptions. Antisera from both of these animals could be rendered specific for lymphocytes, granulocytes and platelets. In the guinea pig only immunization with monocytes and granulocytes resulted in useful antisera, which were all specific for granulocytes after appropriate absorptions. Antisera obtained from rats could be rendered specific for granulocytes and lymphocytes by absorption. Antibodies against platelets could not be detected in any of the rat antisera. Chickens, however, produced strong anti-platelet antibodies. A specific anti-granulocyte antiserum could also be obtained in these animals. Specific anti-monocyte antisera could not be prepared from any of the animal sera. Immunizations with leukocyte lysate resulted in granulocyte-specific antisera in most animals but not in chickens. All antisera produced in chickens were specific for platelets. It can be concluded from these results that animals of different species may react very differenly to the antigens of some human blood cells.