Bookedited by Walter A. Korfmacher.
Contents:
1. Overview of the various types of mass spectrometers that are used in drug discovery and drug development / Gerard Hopfgartner
2. Utility of high resolution mass spectrometry for new drug discovery applications / William Bart Emary and Nanyan Rena Zhang
3. Quantitative mass spectrometry considerations in a regulated environment / Mohammed Jemal and Yuan-Qing Xia
4. Mass spectrometry for quantitative in vitro ADME assays / Jun Zhang and Wilson Z. Shou
5. Metabolite identification using mass spectrometry in drug development / Natalia Penner, Joanna Zgoda-Pols, and Chandra Prakash
6. MS analysis of biological drugs, proteins, and peptides / Yi Du, John Mehl, and Pavlo Pristatsky
7. Characterization of impurities and degradation products in small molecule pharmaceuticals and biologics / Hui Wei, Guodong Chen and Adrienne A. Tymiak
8. Liquid extraction surface analysis (LESA) : a new mass spectrometry-based technique for ambient surface profiling / Dan Eikel and Jack Henion
9. MS applications in support of medicinal chemistry sciences / Maarten Honing, Benno Ingelse, and Birendraÿ N. Pramanik
10. Imaging mass spectrometry of proteins and peptides / Michelle L. Reyzer and Richard M. Caprioli
11. Imaging mass spectrometry for drugs and metabolites / Stacey R. Oppenheimer
12. Screening reactive metabolites : role of liquid chromatography-high resolution mass spectrometry in combination with 'intelligent' data mining tools / Shuguang Ma and Swapan K. Chowdhury
13. Mass spectrometry of siRNA / Mark Cancilla and Mike Flanagan
14. Mass spectrometry for metabolomics / Petia Shipkova and Michael D. Reily
15. Quantitative analysis of peptides with mass spectrometry : selected reaction monitoring or high resolution full scan? / Lieve Dillen and Filip Cuyckens.