BookRoger G. Pertwee, editor.
Summary: There is currently considerable interest in the development of medicines that would enhance endocannabinoid-induced ℓ́ℓautoprotectionℓ́ℓ, for example through inhibition of endocannabinoid metabolizing enzymes or cellular uptake processes or that would oppose endocannabinoid-induced autoimpairment. This volume describes the physiology, pathophysiology and pharmacology of the endocannabinoid system and potential strategies for targeting this system in the clinic.
Contents:
Endocannabinoids and their pharmacological actions / Roger G. Pertwee
Biosynthesis and fate of endocannabinoids / Maria Grazia Cascio, Pietro Marini
Distribution of the endocannabinoid system in the central nervous system / Sherry Shu-Jung Hu, Ken Mackie
The potential of inhibitors of endocannabinoid metabolism for drug development: a critical review / Christopher J. Fowler
Genetic manipulation of the endocannabinoid system / Andreas Zimmer
Endocannabinoids and the immune system in health and disease / Guy A. Cabral, Gabriela A. Ferreira, Melissa J. Jamerson
Endocannabinoids in multiple sclerosis and amyotrophic lateral sclerosis / Gareth Pryce, David Baker
Endocannabinoids and neurodegenerative disorders: Parkinson's disease, Huntington's chorea, Alzheimer's disease, and others / Javier Fernández-Ruiz, Juliìn Romero, Još A. Ramos
Endocannabinoids and mental disorders / TIziana Rubino, Erica Zamberletti, Daniela Parolaro
Cannabis and endocannabinoid signaling in epilepsy / István Katona
Endocannabinoids and the endocrine system in health and disease / Cecilia J. Hillard
Endocannabinoids and reproductive events in health and disease / Natalia Battista, Monica Bari, Mauro Maccarrone
Endocannabinoids and metabolic disorders / Blandine Gatta-Cherifi, Daniela Cota
Endocannabinoids and the cardiovascular system in health and disease / Saoirse Elizabeth O'Sullivan
Endocannabinoids and the digestive tract and bladder in health and disease / Angelo A. Izzo, Giulio G. Muccioli, Michael R. Ruggieri, Rudolf Schicho
Endocannabinoids and cancer / Guillermo Velasco, Cristina Śanchez, Manuel Guzmán.