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  • Book
    edited by Bernhard Kuster.
    Digital : Springer2012
    Targeting cancer with small-molecular-weight kinase inhibitors / Doriano Fabbro [and others] -- Small-molecule protein and lipid kinase inhibitors in inflammation and specific models for their evaluation / Matthias Gaestel and Alexey Kotlyarov -- Measuring the activity of leucine-rich repeat kinase 2 : a kinase involved in Parkinson's disease / Byoung Dae Lee [and others] -- Measuring P13K lipid kinase activity / Elisa Ciraolo, Alessia Perino, and Emilio Hirsch -- A fluorescence polarization assay for the discovery of inhibitors of the polo-box domain of polo-like kinase 1 / Wolfgang Reindl, Klause Strebhardt, and Thorsten Berg -- Assessment of hepatotoxicity potential of drug candidate molecules including kinase inhibitors by hepatocyte imaging assay technology and bile flux imaging assay technology / Jinghai J. Xu [and others] -- Kinase inhibitor selectivity profiling using differential scanning fluorimetry / Oleg Fedorov, Frank H. Niesen, and Stefan Knapp -- Chemoproteomic characterization of protein kinase inhibitors using immobilized ATP / James S. Duncan, Timothy A.J. Haystead, and David W. Litchfield -- Proteome-wide identification of staurosporine-binding kinases using capture coumpound mass spectrometry / Jenny J. Fischer, Olivia Y. Graebner (neé Baessler), and Mathias Dreger -- Affinity pruification of proteins binding to kinase inhibitors immobilized on self-assembling monolayers / Marcus Bantscheff, Scott Hobson, and Bernhard Kuster -- Kinase inhibitor profiling using chemoproteomics / Markus Schirle [and others] -- Covalent cross-linking of kinases with their corresponding peptide substrates / Alexander V. Statsuk and Kevan M. Shokat -- Receptor tyrosine kinase inhibitor profiling using bead-based multiplex sandwich immunoassays / Oliver Pötz [and others] -- Monitoring phosphoproteomic response to targeted kinase inhibitors using reverse-phase protein microarrays / Gabriela Lavezzari and Mark R. Lackner -- Measuring phosphorylation-specific changes in response to kinase inhibitors in mammalian cells using quantitative proteomics / Nurhan Özlü, Marc Kirchner, and Judith Jebanathirajah Steen -- Investigation of acquired resistance to EGFR-targeted therapies in lung cancer using cDNA microarrays / Kian Kani, Rafaella Sordella, and Parag Mallick.