BookJen-Chywan Wang, Charles Harris, editors.
Summary: This timely volume provides a comprehensive overview of glucocorticoids and their role in regulating many aspects of physiology and their use in the treatment of disease. The book is broken into four sections that begin by giving a general introduction to glucocorticoids and a brief history of the field. The second section will discuss the effects of glucocorticoids on metabolism, while the third section will cover the effects of glucocorticoids on key tissues. The final section will discuss general topics, such as animal models in glucocorticoid research and clinical implications of glucocorticoid research. Featuring chapters from leaders in the field, this volume will be of interest to both researchers and clinicians.
Contents:
Section I: Introductory Materials
Regulatory actions of glucocorticoid hormones: from organisms to mechanisms.- Molecular Biology of Glucocorticoid Signaling.-Mechanisms of Glucocorticoid-regulated Gene Transcription
Clinical Perspective: What do Addison and Cushing tell us about Glucocorticoid Action?
Section II: Effects of Glucocorticoids in Metabolism
Regulation of Glucose Homeostasis by Glucocorticoids
How do Glucocorticoids Regulate Lipid Metabolism?
Glucocorticoids and Skeletal Muscle
Section III: Specific Effects of Glucocorticoids on Tissues
Glucocorticoid- induced osteoporosis
Effects of Glucocorticoids on Immune System
Glucocorticoids and the brain: neural mechanisms regulating the stress response
Glucocorticoid Regulation of Reproduction
Glucocorticoids and the lung
Glucocorticoids and the Cardiovascular System
Glucocorticoids and Cancer
Section IV: Miscellaneous Topics
Animal Models of Altered Glucocorticoid Signaling
The Dehydrogenase Hypothesis
Conclusions and Future Directions.
Location
Version
Call Number
Items