BookRobert L. Nussbaum, Roderick R. McInnes, Huntington F. Willard.
Contents:
Introduction to the human genome
The human genome: gene structure and function
Human genetic diversity: mutation and polymorphism
Principles of clinical cytogenetics and genome analysis
The chromosomal and genomic basis of disease: disorders of the autosomes and sex chromosomes
Patterns of single-gene inheritance
Complex inheritance of common multifactorial disorders
Genetic variation in populations
Identifying the genetic basis for human disease
The molecular basis of genetic disease : general principles and lessons from the hemoglobinopathies
The molecular, biochemical, and cellular basis of genetic disease
The treatment of genetic disease
Developmental genetics and birth defects
Cancer genetics and genomics
Risk assessment and genetic counseling
Prenatal diagnosis and screening
Application of genomics to medicine and personalized health care
Ethical and social issues in genetics and genomics.