BookRalph Pantophlet, editor.
Summary: Glycosylation is a common and extremely important modification in biological molecules, particularly of proteins. HIV Glycans in Infection and Immunity provides an overview of the roles of glycans in the transmission/infection, antigenicity, and immunogenicity of HIV and the HIV envelope glycoprotein. It explores recent advances in the understanding of the impact of HIV glycans in infection and their promise for immunological and therapeutic intervention. Novel collaborations between glycobiologists and immunologists in recent years have led to key advances in the understanding of HIV glycans. These cross-disciplinary endeavors, their achievements and their impact on the field are all addressed, herein.-- Source other than Library of Congress.
Contents:
HIV glycomics and glycoproteomics / Camille Bonomelli ... [et al.]
Innate recognition of HIV-1 glycans : implications for infection, transmission, and immunity / Angelic M.G. van der Aar, Sonja I. Gringhuis, and teunis B.H. Geijtenbeek
The influence of HIV enveloppe glycosylation on adaptive immune response / Catarina E. Hioe, Rajnish Kumar, and Shiu-Lok Hu
Role of HIV glycans in transmission and immune escape / Penny L. Moore, Megan K. Murphy, and Cynthia A. Derdeyn
Molecular recognition of HIV glycans by antibodies / Leopold Kong, Robyn L. Stanfield, and Ian A. Wilson
Anti-carbohydrate HIV vaccine design / Lai-Xi Wang ... [et al.]
Lectins as HIV microbicides / Leonardus M.I. Koharudin and Angela M. Gronenborn.