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  Advances in Psoriasis : a Multisystemic Guide. First edition

  edited by Jeffrey M. Weinberg, Mark Lebwohl.

  Summary: The understanding and management of psoriasis have evolved dramatically over the last decades and, as a result, guidelines and treatment options have changed dramatically. To meet the need for a up-to-date practical resource in this area, the Editors have brought together a team of experts in the field to produce a highly informative and illustrated guide to the decision-making process for psoriasis. Advances in Psoriasis: A Multisystemic Guide provides physicians with a reference on the disease and its comorbidities and therapeutic options. It will help physicians further their knowledge of the science and therapy of psoriasis. As well as practicing dermatologists, fellows in dermatology will find this book to be an essential training resource to learn about the treatment and management of psoriasis.
  
  Contents:
  Introduction to Psoriasis and Psoriasis Therapy
  Pathophysiology of Psoriasis/Novel Pathways
  Psoriasis and Psoriasis Arthritis: Clinical Review and Update
  Overview of Therapeutic Options/Pharmacology
  Topical Therapy
  Ultraviolet and Laser Therapy
  Traditional Systemic Therapy
  Biologics I: TNF Inhibitors
  Biologics II: IL-12/23 and T-Cell Targeted Therapy
  Research Pipeline I: Topicals and Oral Therapies
  Research Pipeline II: Biologic Therapies
  Summary of Published Treatment Guidelines
  Reimbursement Issues/Aides
  Patient Support Programs and Organizations
  Conclusion
  Appendix: Directory of Helpful Websites/Online Resources/Telephone Numbers.

  Digital Access Springer 2014
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• Article

  Coopération entre cellules adhérentes et lymphocytes T mutins pour la synthèse in vitro d'interféron Brucello-induit. [Adherent cell and T lymphocyte cooperation for the "in vitro" production of Brucella-induced interferon by murine spleen cells (author's transl)].

  Bousquet C, Cannat A, Ramuz M, Serre A.

  Ann Immunol (Paris). 1978 Jul-Sep;129 C(5):715-9.

  Although Brucella is a good in vivo inducer of interferon, in vitro infection of murine spleen cells by Brucella suis has not, to the present time, led to in vitro synthesis. In the present work we show that normal spleen cells can however synthetize interferon in vitro when cultured together with adherent cells obtained from the spleens of syngeneic mice 45 min after in vivo inoculation. Induction and synthesis are thus shown to be distinct phenomena. Moreover soluble factors are shown to be involved in the induction phenomenon and T cells to be essential for synthesis. This in vitro brucella-induced interferon differs from in vivo brucella-induced interferon: its acid lability and its antigenic properties are characteristic of type II "immune" interferon.

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  PubMed