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  • Book
    Lars Kaestner.
    Contents:
    Summary
    Introduction
    Direct evidence - the digital approach
    Fluorescence-based visualisation
    Aequorin-based measurements
    Measurement of calcium transport across membranes
    Molecular biology based approaches
    Manipulation of calcium
    Calcium-induced function
    Calcium signalling in cardiac myocytes
    Calcium signalling in red blood cells
    Perspective
    Calcium Signalling Methodology
    Non-linear and ultra high-speed imaging for explorations of the murine and human heart
    A system for optical high resolution screening of electrical excitable cells
    Concepts for optical high content screens of excitable primary isolated cells
    A primary culture system for sustained expression of a calcium sensor in preserved adult rat ventricular myocytes
    Calcium imaging of individual erythrocytes: Problems and approaches
    Calcium Signalling in Cardiac Myocytes
    Reduced Cardiac L-Type Ca²+ Current in Cav€ ₂ -/- Embryos Impairs Cardiac Development and Contraction With Secondary Defects in Vascular Maturation
    Overexpression of junctin causes adaptive changes in cardiac myocyte Ca²+ signaling
    Remodelling of Ca²+ handling organelles in adult rat ventricular myocytes during longterm culture
    Functional and morphological preservation of adult ventricular myocytes in culture by sub-micromolar cytochalasin D supplement
    Calcium Signalling in Red Blood Cells
    The non-selective voltage-activated cation channel in the human red blood cell membrane: reconciliation between two conflicting reports and further characterisation
    Ion channels in the human red blood cell membrane: Their further investigation and physiological relevance
    Prostaglandin E₂ activates channelmediated calcium entry in human erythrocytes: An indication for a blood clot formation supporting process
    Functional NMDA receptors in rat erythrocytes
    Stimulation of human red blood cells leads to Ca²+-mediated intercellular adhesion
    Lysophospatidic acid induced red blood cell aggregation in vitro
    Regulation of phosphatidylserine exposure in red blood cells
    Cation Channels in Erythrocytes - Historical and Future Perspective.
    Digital Access Springer 2013
  • Article
    Zabik JE, Liao SS, Jeffreys M, Maickel RP.
    Res Commun Chem Pathol Pharmacol. 1978 Apr;20(1):69-78.
    Rats were offered access to either distilled water or a 12% v/v solution of ethanol as their only fluid during a one hour period daily. After daily fluid consumption has achieved a stable baseline, either distilled water or DL-5-hydroxytryptophan (5HTP) in doses of 50, 100 or 200 mg/kg was injected intraperitoneally one hour prior to the drinking session. While each of the three doses of 5HTP caused a significant reduction in ethanol intake, distilled water had no effect. Water consumption was unaffected by 5HTP or distilled water injections. Varying the pretreatment interval from 0.5, 1, 4 to 8 hours for the 100 mg/kg 5HTP dose resulted in a significant decrease in ethanol consumption at 0.5 and 1 hour pretreatment intervals only. In approximately 25% of the rats tested, 5HTP resulted in a prolonged rejection of ethanol so severe that it resulted in death. Selected rats offered water during this ethanol rejection period readily drank it and survived.
    Digital Access Access Options