BookDarren R. Flower, Yvonne Perrie, editors.
Summary: This book seeks to expand the horizons of vaccine design and discovery by highlighting cutting edge work in three areas of vaccinology: the rational discovery of subunit vaccines, the identification of adjuvants, and the delivery of vaccines via state-of-the-art nanotechnology.
Contents:
Immunomic discovery of adjuvants, delivery systems, and candidate subunit vaccines : a brief introduction / Darren R. Flower and Yvonne Perrie
Bacterial genomes and vaccine design / Valeria Cafardi, John L. Telford, and Davide Serruto
Identification of candidate vaccine antigens in silico / Darren R. Flower, Matthew N. Davies, and Irini A. Doytchinova
Post-genomic antigen discovery : bioinformatical approaches to reveal novel T cell antigens of Mycobacterium bovis / Martin Vordermeier [and 3 others]
Genome-based computational vaccine discovery by reverse vaccinology / Yongqun He
Computational prediction of protein subcellular localization, genomic islands, and virulence to aid antigen discovery / Bhavjinder K. Dhillon, Nancy Y. Yu, and Fiona S.L. Brinkman
On the development of vaccine antigen databases : progress, opportunity, and challenge / Hifzur Rahman Ansari, Darren R. Flower, and Gajendra P.S. Raghava
What have dendritic cells ever done for adjuvant design? : cellular and molecular methods for the rational development of vaccine adjuvants / Alexander D. Edwards
Towards the systematic discovery of immunomodulatory adjuvants / Darren R. Flower
Designing liposomes as vaccine adjuvants / Malou Henriksen-Lacey and Yvonne Perrie
Designing nonionic surfactant vesicles for the delivery of antigens for systemic and alternative delivery routes / Jitinder Wilkhu [and 3 others]
Immune stimulating complexes (ISCOMs) and Quil-A containing particulate formulations as vaccine delivery systems / S. Hook and T. Rades
Formulation and characterisation of PLGA microspheres as vaccine adjuvants / Daniel J. Kirby, Randip Kaur, and Yvonne Perrie
Powder vaccines for pulmonary delivery / Tom Jin and Eric Tsao.