BookBrian Henderson, A. Graham Pockley, editors.
Contents:
Section 1 Historical Introduction to Secreted Cell Stress Proteins as Signalling Proteins
Discovery of the Cellular Secretion of Cell Stress Proteins
Discovery of the Agonist Activities of Molecular Chaperones and Protein-Folding Catalysts
Identification of Cell Stress Proteins in Biological Fluids
Section 2 Intracellular Trafficking of Molecular Chaperones and its Consequences
Hsp27 Phosphorylation Patterns and Cellular Consequences
Evidence on Cholesterol-Controlled Lipid Raft Interaction of the Small Heat Shock Protein HSPB11
Hsp70 Chaperone Systems in Vesicular Trafficking
Pathways of Hsp70 Release: Lessons from Cytokine Secretion
Nucleolin: A Novel Intracellular Transporter of HSPA1A
The Hsp90-Based Protein Trafficking System and Linkage to Protein Quality Control
Section 3 Molecular Chaperones as Cell Surface Receptors and Receptor Ligands
Cell Surface Molecular Chaperones and the LPS Receptor
Hsp60: An Unexpected Cell Surface Receptor in Prokaryotes and Eukaryotes
Pathophysiological Barriers Impeding the Delivery of Heat Shock Protein (HSP)-based Macromolecules and Nanotherapeutics to Solid Tumors
The Chaperokine Activity of HSPA1A
Molecular Chaperones and Scavenger Receptors: Binding and Trafficking of Molecular Chaperones by Class F and Class H Scavenger Receptors
Grp78 (BiP): A Multifunctional Cell Surface Receptor
Section 4 Extracellular Secretion of Molecular Chaperones in Prokaryotes and Eukaryotes
Mycobacterium Tuberculosis Hsp60 as a Key Virulence Factor in Tuberculosis
Hsp90 vs Conventional Growth Factors in Acute and Diabetic Wound Healing
Circulating Molecular Chaperones in Health and Disease
Index.