BookThomsen, Henrik S.; Webb, Judith A. W.
Summary: In 1994 the European Society of Urogenital Radiology (ESUR) set up a committee to consider the safety of contrast media used for diagnostic imaging. Subsequently the committee questioned ESUR members, reviewed the literature, proposed guidelines, and discussed these proposals with participants at the annual symposia of the society. The end result of this work was the successful first edition of this book, published in 2006, which was followed by an equally successful second edition in 2009. This third edition not only fully updates the previous edition, but also includes new chapters on complex topics such as use of contrast media in children and practical aspects of off-label contrast media use. The authorship includes members, past members, and non-members of the Contrast Media Safety Committee. Comprehensive consideration is given to the many different safety issues relating to iodine-based contrast media, gadolinium-based contrast media, microbubbles for ultrasound, and barium sulfate. The text includes chapters on both acute and delayed non-renal adverse reactions and on renal adverse reactions. All of the questions frequently raised in radiological practice are addressed. This book, presented in a handy, easy-to-use format, provides an invaluable, unique, and unparalleled source of information.
Contents:
General Issues: Classification and Terminology
Requests for Imaging using contrast agents: What information must be provided
Off-label use of medicines: legal aspects
Off-label use of contrast media: practical aspects
Pharmacovigilance: When to report adverse reactions to contrast media
What is required to get the authorities to approve a new contrast medium?
A critical review of meta-analysis of adverse events after contrast media
Iodine- and Gadolinium-Based Contrast Media: General Adverse Reactions: Acute adverse reactions to contrast media: Mechanisms and prevention
Iodine-based contrast medium temperature and adverse reactions
Management of acute adverse reactions to contrast media
Renal Adverse reactions:Chronic kidney disease, serum creatinine and estimated glomerular filtration rate (eGFR)
Contrast medium-induced nephropathy
Dialysis and contrast media
Other adverse effects: Pregnancy and lactation: intravascular use of contrast media
Pheochromocytoma and contrast media
Contrast media and interactions with other drugs and clinical tests
Contrast media extravasation injury
Iodine-based contrast media: Late adverse reactions to iodine-based contrast media
Effects of iodine-based contrast media on blood and endothelium
Effects of iodine-based contrast media on thyroid function
Pulmonary effects of iodine-based contrast media
MR contrast media: Gadolinium chelates and stability
Diagnostic efficacy of gadolinium-based contrast media
Radiography with gadolinium-based contrast media
Acute adverse reactions to gadolinium-based contrast media
Nephrogenic systemic fibrosis and gadolinium- based contrast media
Organ specific gadolinium-based contrast media
Ultrasonographic Contrast media
Barium Preparations: Barium preparations: safety issues
Pediatric use of Contrast Media: Contrast media use in pediatrics: Safety issues
Appendix: ESUR Guidelines on Contrast Media Version 8.1
Official publications from the Contrast Media Safety Committee of the European Society of Urogenital Radiology.