BookHe-Feng Huang, Jian-Zhong Sheng, editors.
Summary: The book Gamete and Embryo-fetal Origins of Adult Diseases introduces various diseases resulting from the abnormal gametogenesis and embryo development, which manifests as growth retardation, birth defects, or increased susceptibility to chronic metabolic diseases such as diabetes, cardiovascular disease and cancer in childhood and adult life, even fertility disorders and the risk of transgenerational transmission. Six common kinds of these diseases are discussed in separate chapters. The authors explore the connections between these diseases and epigenetic reprogramming, rapid cell differentiation and organ formation and environmental influences, including assisted reproductive technology and adverse intrauterine environments. With a summary of findings on the causes and progression of adult diseases at the phase of gametogenesis and embryo development, this book provides insights into the pathogenesis of disease and aids in the treatment and prevention of disease, meeting the requirement for improving the quality of the newborn population, and effectively preventing and curing major diseases at an early stage. This book offers new perspectives and will be an enlightening resource for obstetricians, paediatricians, epidemiologists, endocrinologists and sanitarians.
Contents:
Physiology of gametogenesis
Physiology of embryo development
Diabetes originated from embryo-fetal development
Cardiovascular disease originated from embryo-fetal development
Tumor originated from embryo-fetal development
Obesity originated from embryo-fetal development
Infertility originated from embryo-fetal development
Mental health originated from embryo-fetal development
Assisted reproductive technology (ART) and embryo-fetal origin of diseases
Adverse intrauterine environment and embryo-fetal origin of diseases.