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  • Book
    Eng H. Lo, Josephine Lok, MingMing Ning, Michael J. Whalen, editors.
    Summary: Vascular Mechanisms in CNS Trauma focuses on the vascular aspects of brain and spinal cord trauma.Twenty nine chapters are arranged in three sections:Molecular Mechanisms; Experimental Models and Methods; and Clinical Challenges and Opportunities. The first section addresses topics in the basic biology of brain and spinal cord trauma, ranging from the pathophysiology of cerebral endothelial cells and gliovascular interactions to the role of stem cells in neurovascular repair. The second section covers experimental methods in rodent and in large animal models of CNS injury, as well as the use of biomaterials and biomarkers in studying the mechanisms of tissue response. The third section deals with clinical issues in the monitoring and treatment of the patient with traumatic injury of the brain and spinal cord. Contributors to the book include an integrated mix of basic scientists and clinicians from diverse institutions. By presenting salient issues in CNS trauma from a vascular perspective, this book should make a unique contribution to the understanding of traumatic brain and spinal cord injury.

    CNS Barriers in Neurotrauma
    Mechanisms of Cerebral Edema Leading to Early Seizures after Traumatic Brain Injury
    Human Cerebral Blood Flow and Traumatic Brain Injury
    Gliovascular Targets in Traumatic CNS Injury
    Neurovascular Responses to Traumatic Brain Injury
    The Effects of Intravascular Coagulation and Microthrombosis on Cerebral Perfusion after Brain Trauma
    Barriers to Drug Delivery for Brain Trauma
    Angiogenesis and Functional Recovery after Traumatic Brain Injury
    Vascular Mechanisms in Spinal Cord Injury
    Neurovascular Mechanisms of Ischemia Tolerance Against Brain Injury
    Stem Cells for Neurovascular Repair in CNS Trauma
    Vascular Actions of Hypothermia in Brain Trauma
    Vascular Responses in Rodent Models of Traumatic Brain Injury
    SAH Models: Review, New Modification, and Prospective
    Age and Sex Differences In Hemodynamics In a Large Animal Model of Brain Trauma
    Neutrophils as Determinants of Vascular Stability in the Injured Spinal Cord
    Blood Biomarkers for Acute CNS Insults: Traumatic Brain Injury and Stroke
    Biomaterials for CNS Injury
    Isolated Blood Vessel Models for Studying Trauma
    Managing Edema and Intracranial Pressure in the Intensive Care Unit
    Surgical Management of Traumatic Brain Edema
    Optimizing Hemodynamics in the Clinical Setting
    Cerebrovascular Autoregulation and Monitoring of Cerebrovascular Reactivity
    Cerebrovascular Responses after Pediatric Traumatic Brain Injury
    Subdural Hematoma in Non-Accidental Head Injury
    Blood Genomics after Brain Ischemia, Hemorrhage, and Trauma
    Molecular Biomarkers in Neurocritical Care ? The Next Frontier
    Bedside Monitoring of Vascular Mechanisms in CNS Trauma: The use of Near Infra-red Spectroscopy (NIRS) and Transcranial Doppler (TCD)
    In vivo MRI and MRS of Cerebrovascular Function following Traumatic Brain Injury.
    Digital Access Springer 2014