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    Gheorghe Andrei Dan, Antoni Bayés de Luna, John Camm, editors.
    Summary: The paradigm for atrial fibrillation (AF) management has changed significantly in recent years. A new era has begun for the prevention of one of the most tremendous complication of AF, stroke. Prevention of ischemic stroke in AF patients with oral anticoagulants represents a huge challenge because of the narrow therapeutic change of these drugs, interindividual and intraindividual variability, and the unsatisfactory time in therapeutically range (TTR) with this type of medication.

    Contents:
    1. Epidemiology, Burden and Unmet Needs in Atrial Fibrillation / Antoni Martínez-Rubio, Josep Guindo Soldevila, and Antoni Bayés de Luna
    2. Inside Molecular Mechanisms and Pharmacological Targets of Atrial Fibrillation / Alina Scridon and Dan Dobreanu
    3. Novel Oral Anticoagulants for Stroke Prevention in Patients with Non-valvular Atrial Fibrillation / Yoseph Rozenman and Yuri Gluzman
    4. Upstream Therapy in the Treatment of Atrial Fibrillation / Cristian Baicus
    5. Drug Therapy for Rhythm and Rate Control in Atrial Fibrillation / Josep Guindo Soldevila and Antoni Martinez-Rubio
    6. Changing the Paradigm to Understand and Manage Atrial Fibrillation / Gheorghe-Andrei Dan
    7. Guidelines and Current Recommendations in Atrial Fibrillation / Antoni Martínez-Rubio and Gheorghe-Andrei Dan.
    Digital Access Springer 2014