BookEdward K. L. Chan, Marvin J. Fritzler, editors.
Contents:
Introduction: The GW Body Story as an Example of Autoantibodies with Significant Impacts to Molecular Cell Biology
The Discovery of GW Bodies
The Discovery and Analysis of P Bodies
Autoantibodies to Argonaute 2 (Su Antigen)
GW/P-Bodies and Autoimmune Disease
Function of GW182 and GW Bodies in siRNA and miRNA Pathways
Post-transcriptional Stimulation of Gene Expression by MicroRNAs
Gawky (GW) is the Drosophila melanogaster GW182 Homologue
The Role of GW182 Proteins in miRNA-Mediated Gene Silencing
Quantifying Argonaute Proteins In and Out of GW/P-Bodies: Implications in microRNA Activities
Deadenylation and P-Bodies
Relationship of GW/P-Bodies with Stress Granules
Relationship of Other Cytoplasmic Ribonucleoprotein Bodies (cRNPB) to GW/P Bodies
An SNP in the Trinucleotide Repeat Region of the TNRC6A Gene Maps to a Major TNGW1 Autoepitope in Patients with Autoantibodies to GW182
Reflections on Ten Years of History of, and Future Prospects for, GW182 and GW/P Body Research.
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