BookSelene Baschieri, editor.
Summary: Prevention of infectious diseases by vaccination is one of the most significant achievements of modern medicine. During the 20th century, the average human life span in the developed world was about 70 years and it is expected to increase, with a significant portion of this increase directly attributed to vaccination. Since the first empiric vaccination trials, knowledge and technology have enormously evolved and new vaccination strategies are emerging on the market. Indeed, in spite of the great success, conventional vaccination strategies sometimes may result ineffective and, above all, may
Contents:
Part 1. Vaccine design
Design of New Vaccines in the Genomic and Post-genomic Era / Laura Serino, Kate L. Seib and Mariagrazia Pizza
Comparing In Silico Results to In Vivo and Ex Vivo of Influenza-Specific Immune Responses After Vaccination or Infection in Humans / Filippo Castiglione, Benjamin Ribba and Olivier Brass
Part 2. Vaccine delivery
Virus Glycoproteins Tagged with the Human Fc Domain as Second Generation Vaccine Candidates / Silvia Loureiro, Elena Robinson, Hongying Chen, Pongsathon Phapugrangkul and Camilo Colaco, et al.
Engineered Viruses as Vaccine Platforms / Antonella Folgori and Stefania Capone
Virus-Like Particles as Efficient Delivery Platform to Induce a Potent Immune Response / Fabien Rebeaud and Martin Bachmann
Filamentous Bacteriophages: An Antigen and Gene Delivery System / Rossella Sartorius, Domenico Russo, Luciana D'Apice and Piergiuseppe De Berardinis
Liposomes and Other Nanoparticles as Cancer Vaccines and Immunotherapeutics / Joseph G. Altin
Plant-Based Vaccine Delivery Strategies / Chiara Lico, Carla Marusic, Floriana Capuano, Giampaolo Buriani and Eugenio Benvenuto, et al.
TLR Agonists as Vaccine Adjuvants / Mark A. Tomai and John P. Vasilakos
Mucosal Vaccines for Enteric Bacterial Pathogens / Paolo Pasquali
Part 3. Pre-clinical Vaccine Testing
The Importance of Animal Models in the Development of Vaccines / Tadele G. Kiros, Benoît Levast, Gaël Auray, Stacy Strom and Jill van Kessel, et al.
Correlates of Vaccine-Induced Immunity: Historical Perspectives and Future Challenges / Ian J. Amanna.