BookWolfgang H. Sommer, Rainer Spanagel, editors.
Part I. Mechanistic Aspects Underlying Alcoholism -- Theoretical Frameworks and Mechanistic Aspects of Alcohol Addiction: Alcohol Addiction as a Reward Deficit Disorder / George F. Koob -- Synaptic Effects Induced by Alcohol / David M. Lovinger and Marisa Roberto -- Signaling Pathways Mediating Alcohol Effects / Dorit Ron and Robert O. Messing -- Neurocircuitry Involved in the Development of Alcohol Addiction: The Dopamine System and its Access Points / Bo Söderpalm and Mia Ericson -- What is in that Drink: The Biological Actions of Ethanol, Acetaldehyde, and Salsolinol / Gerald A. Deehan Jr., Mark S. Brodie and Zachary A. Rodd -- Part II. Genetics -- Modeling the Diagnostic Criteria for Alcohol Dependence with Genetic Animal Models / John C. Crabbe, Kenneth S. Kendler and Robert J. Hitzemann -- Non-Human Primate Models of Alcohol-Related Phenotypes: The Influence of Genetic and Environmental Factors / Christina S. Barr -- Genetically Selected Alcohol Preferring Rats to Model Human -- Alcoholism / Roberto Ciccocioppo -- Advanced Transgenic Approaches to Understand Alcohol-Related Phenotypes in Animals / Ainhoa Bilbao -- Part III. Clinical Phenotypes and Preclinical Models Thereof Modeling Alcohol Self-Administration in the Human Laboratory / Ulrich S. Zimmermann, Sean O'Connor and Vijay A. Ramchandani -- Animal Models of Excessive Alcohol Consumption in Rodents / Howard C. Becker -- Modeling Relapse Situations in the Human Laboratory / Rajita Sinha -- Modeling Relapse in Animals / Rémi Martin-Fardon and Friedbert Weiss -- Invertebrate Models of Alcoholism / Henrike Scholz and Julie A. Mustard -- Part IV. Novel Insights from Brain Imaging The Dopamine System in Mediating Alcohol Effects in Humans / K. Charlet, A. Beck and A. Heinz -- Stimulant and Sedative Effects of Alcohol / Reuben A. Hendler, Vijay A. Ramchandani, Jodi Gilman and Daniel W. Hommer -- Chronic Alcohol Consumption, Abstinence and Relapse: Brain Proton Magnetic Resonance Spectroscopy Studies in Animals and Humans / Dieter J. Meyerhoff, Timothy C. Durazzo and Gabriele Ende -- Part V. Translational Aspects and Medication Development -- Translational Approaches to Medication Development / Selena Bartlett and Markus Heilig -- New Pharmacological Treatment Strategies for Relapse Prevention / Rainer Spanagel and Valentina Vengeliene -- The Challenge of Studying Parallel Behaviors in Humans and Animal Models / David N. Stephens, Hans S. Crombag and Theodora Duka -- A Translational Approach to Novel Medication Development for Protracted Abstinence / Barbara J. Mason and Amanda E. Higley -- New Approaches to Addiction Treatment Based on Learning and Memory / Falk Kiefer and Christina Dinter -- Adolescent Substance Misuse: Neurobiology and Evidence-Based Interventions / Nicola C. Newton, Maeve O'Leary-Barrett and Patricia J. Conrod -- Deep Brain Stimulation as a Therapy for Alcohol Addiction / Thomas F. Münte, Hans-Jochen Heinze and Veerle Visser-Vandewalle.