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  • Book
    edited by Amitava Dasgupta.
    Summary: Therapeutic Drug Monitoring: Newer Drugs and Biomarkers features timely topics such as the monitoring of classical and newer drugs, pharmacogenomics and the application of biomarkers in therapeutic drug monitoring. This reference also discusses the limitations of current commercially available immunoassays for therapeutic monitoring. It presentsssnew and sophisticated techniques used for proper determination of blood levels and the clinical utility of therapeutic drug monitoring of contemporary drugs. Written by leading international experts and geared toward clinical pathol.

    Contents:
    Front matter
    Copyright
    Contributers
    Chapter 1. Introduction to therapeutic drug monitoring: frequently and less frequently monitored drugs
    Chapter 2. Effects of pre-analytical variables in therapeutic drug monitoring
    Chapter 3. Analytical techniques used in therapeutic drug monitoring
    Chapter 4. Clinical utility of free drug monitoring
    Chapter 5. Current practice of therapeutic drug monitoring: dose adjustment of drugs using pharmacokinetic models
    Chapter 6. An introduction to personalized medicine
    Chapter 7. Application of ultra-high throughput sequencing and microarray technologies in pharmacogenomics testing
    Chapter 8. Pharmacogenomics and Warfarin therapy
    Chapter 9. Applications of pharmacokinetic and pharmacodynamic principles to optimize drug dosage selection: example of antibiotic therapy management
    Chapter 10. Guidelines for the monitoring of vancomycin, aminoglycosides and certain antibiotics
    Chapter 11. Challenges in therapeutic drug monitoring of digoxin and other anti-arrhythmic drugs
    Chapter 12. Therapeutic drug monitoring of classical and newer anticonvulsants
    Chapter 13. Challenges in therapeutic drug monitoring of classical tricyclic and newer antidepressants: analytical and pharmacogenetics considerations
    Chapter 14. Therapeutic drug monitoring of selected anticancer drugs: pharmacogenomics issues
    Chapter 15. Immunosuppressive drug monitoring: limitations of immunoassays and the application of liquid chromatography mass spectrometry
    Chapter 16. Biomarkers: the link between therapeutic drug monitoring and pharmacodynamics of immunosuppressants
    Chapter 17. Therapeutic drug monitoring of antiretroviral drugs in the management of human immunodeficiency virus infection
    Chapter 18. Drug testing in pain management
    Chapter 19. Effect of herbal supplement-drug interactions on therapeutic drug monitoring
    Index.
    Digital Access ScienceDirect 2012