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  • Book
    Sima Jain, author and editor.
    Contents:
    Basic Science and Immunology
    Pediatric Dermatology
    General Dermatology
    Infectious Diseases
    Benign and Malignant Tumors
    Dermatologic Surgery
    Pharmacology and Drug Reactions
    Pathology
    Dermoscopy and Electron Microscopy
    Life After Boards
    High Yield Facts and Buzz Words.
    Digital Access Springer 2012
  • Article
    Westhof E, Plach H, Cuno I, Lüdemann HD.
    Nucleic Acids Res. 1977 Apr;4(4):939-53.
    Proton magnetic resonance studies of 2'-deoxyadenosine (2'-dA), 3'-deoxyadenosine (3'-dA), 5'-deoxyadenosine (5'-dA) and 8-bromo-5'-deoxyadenosine (8-Br-5'-dA) have been carried out in the temperature range between -60 degrees and +40 degrees C for ND3 solutios, +40 degrees and +100 degrees C for D2O solutions, and finally +10 degrees and +60 degrees C for pyridine solutions. The analysis is based on the two-state S in equilibrium N model of the ribose moiety proposed by Altona and Sundaralingam. In all solvents, 2'-dA favours slightly the S state of the ribose and the g+ conformer of the exocyclic CH2OH group. However, 3'-dA prefers strongly the N state of the ribose and the g+ conformation. Both the S and N states of the ribose are equally favoured by 5'-DA and 8-Br-5'-dA. Evidence for the existence of an intramolecular hydrogen bond between 0(5') and N3 in purine (beta)-nucleosides is presented. It is also concluded that cordycepin (3'-dA) exists in solution mainly in the anti conformation of the base relative to the ribose.
    Digital Access Access Options