Bookedited by Antonio Rodriguez-Moreno, Talvinder S. Sihra.
Summary: "This volume critically examines the functional actions of the kainate type glutamate receptors (KARs). Following on from the larger body of work on the NMDA and AMPA-type ionotropic glutamate receptors (GluRs), studies with KARs have consistently thrown up exceptions to general rules about synaptic modulation. Contributors herein provide an insight to the idiosyncracies that now almost typify the KAR field. The fascinating insights provided in this volume serve to encourage searching mechanistic questions"--Provided by publisher.
Contents:
Metabotropic actions of kainate receptors in the control of GABA release
In the developing hippocampus kainate receptors control the release of GABA from mossy fiber terminals via a metabotropic type of action
Localization and functions of kainate receptors in the basal ganglia
Metabotropic actions of kainate receptors in the control of glutamate release in the hippocampus
Metabotropic actions of kainate receptors in the regulation of IsAHP and excitability in CA1 pyramidal cells
Kainate receptors with a metabotropic signature enhance hippocampal excitability by regulating the slow after-hyperpolarization in CA3 pyramidal neurons
Metabotropic actions of kainate receptors in dorsal root ganglion cells
Role of kainate receptors in network activity during development
Kainate receptor modulation by sodium and chloride
BTB kelch proteins and ubiquitination of kainate receptors.
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