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  • Book
    JoAnn M. Mould, Paul M. Ness, Steve R. Sloan, editors.
    Summary: This text is a review of molecular immunohematology (MI). It draws from analyses and case studies around the world and details many techniques used in many labs. It is aimed at anyone interested in how MI is changing blood bank and transfusion medicine.

    Contents:
    1. An overview of the classic serological methods: limitations and benefits of serology and DNA testing
    2. Introduction to molecular typing
    3. The BeadChip system: a flexible array format for complex nucleic acid and protein analysis
    4. Implementation of HEA at blood centers: prescreening, rare donors, inventory management
    5. Implementation of HEA BeadChip system at medical centers: providing extended matched units and eliminating complex workups for patients
    6. Human platelet antigen genotyping and diagnosis of antiplatelet alloimmunization
    7. Blood group genotyping by high-throughput DNA-analysis: application to the Panel National de Reference du CNRGS
    8. Implementation and assessment of high-throughput donor typing at the Milan, Italy, Immunohematology Reference Laboratory
    9. Impleentation of the BioArray Human Erythrocyte Antigen (HEA) BeadChip system: the Spanish Red Cross Blood Centre of Madrid, Spain experience
    10. Looking beyond HEA: matching SCD patients for RH variants
    11. Identification of altered RHD and RHCE alleles: a comparison of manual and automated molecular methods
    12. Bayesian classification algorithms for automated allele assignment
    Index.
    Digital Access Springer 2011