BookJaime M. Monti, S. R. Pandi-Perumal, Hanns Möhler, editors.
Contents:
Part 1. Basic Physiology and Pharmacology
Physiology and Pharmacology of the GABA System: Focus on GABA Receptors / Hanns Möhler
Development of Subtype-Selective GABAA Receptor Compounds for the Treatment of Anxiety, Sleep Disorders and Epilepsy / John R. Atack
Distribution of GABAA Receptor Subunits in the Human Brain / H. J Waldvogel, K Baer and R. L. M. Faull
Pharmacokinetic Determinants of the Clinical Effects of Benzodiazepine Agonist Hypnotics / David J. Greenblatt
Part 2. Sleep Science and Circuitry
Sleep and Its Modulation by Substances That Affect GABAA Receptor Function / Axel Steiger
Subcortical Neuromodulation of Feedforward and Feedback Inhibitory Microcircuits by the Reticular Activating System / J. Josh Lawrence
Function of GABAB and ρ-Containing GABAA Receptors (GABAC Receptors) in the Regulation of Basic and Higher Integrated Sleep-Waking Processes / Claude Gottesmann
Interactions Between GABAergic and Serotonergic Processes in the Dorsal Raphe Nucleus in the Control of REM Sleep and Wakefulness / Jaime M. Monti
GABA-ergic Modulation of Pontine Cholinergic and Noradrenergic Neurons for REM Sleep Generation / Dinesh Pal and Birendra Nath Mallick
Involvement of GABAergic Mechanisms in the Laterodorsal and Pedunculopontine Tegmental Nuclei (LDT-PPT) in the Promotion of REM Sleep / Pablo Torterolo and Giancarlo Vanini
GABAergic Mechanisms in the Ventral Oral Pontine Tegmentum: The REM Sleep-Induction Site - in the Modulation of Sleep-Wake States / Fernando Reinoso-Suárez, Carmen de la Roza, Margarita L Rodrigo-Angulo, Isabel de Andrés and Ángel Núñez, et al.
The Role of GABAergic Modulation of Mesopontine Cholinergic Neurotransmission in Rapid Eye Movement (REM) Sleep / Gerald A Marks and Christopher M Sinton
Melatonin and Sleep: Possible Involvement of GABAergic Mechanisms / Daniel P. Cardinali, S. R. Pandi-Perumal, Lennard P. Niles and Gregory M. Brown
GABA Involvement in the Circadian Regulation of Sleep / J. Christopher Ehlen, Daniel L. Hummer, Ketema N. Paul and H. Elliott Albers
Part 3. Neurotherapeutics
Pathophysiology of Sleep Disorders / Thomas C. Wetter, Pierre A. Beitinger, Marie E. Beitinger and Bastian Wollweber
Insomnia: Differential Diagnosis and Current Treatment Approach / J. F Pagel and Gerald Kram
Zolpidem in the Treatment of Adult and Elderly Primary Insomnia Patients / Luc Staner, Françoise Cornette, Sarah Otmani, Jean -François Nedelec and Philippe Danjou
Efficacy and Safety of Zopiclone and Eszopiclone in the Treatment of Primary and Comorbid Insomnia / Jadwiga S. Najib
Indiplon / David N. Neubauer
Polysomnographic and Clinical Assessment of Zaleplon for the Treatment of Primary Insomnia / Joseph Barbera and Colin Shapiro.