Prologue: World Health Concerns -- History of Bilirubin -- Biochemistry and Physiology of Bilirubin -- Premature Birth -- Erythroblastosis Fetalis -- The Gunn Rat Model -- Crigler-Najjar Syndrome -- Neuropathology of Kernicterus -- Bilirubin and Energy Metabolism -- Jaundice and Other Biochemical Changes -- Breast Milk Jaundice -- Jaundice in Malaria -- Jaundice in Congenital Hypertrophic Pyloric Stenosis -- Phototherapy for Hyperbilirubinemia -- Non-phototherapy Treatment -- Hyperbilirubinemia Revisited -- Auditory Brainstem Response -- Progressive Familial Intrahepatic Cholestasis -- Kernicterus in Older Children and Adults -- Cerebral Palsy and Counseling -- Neurological Sequelae from Jaundice -- Neurobehavioral Teratology -- Gene Therapy for Hyperbilirubinemia -- Epilogue: Comments and Future Directions.