Bookedited by Hua Feng, Ying Mao, John H. Zhang.
Summary: More than 40 articles provide an extensive coverage of advances over the last three years of research on subarachnoid hemorrhage-induced brain injuries and cerebral vasospasm. Early brain injury, the new frontier of subarachnoid hemorrhage research, which may be a key contributor to the high mortality and morbidity, promotes collaborative efforts from neurosurgery, neurology, neuro-ICU into other interrelated fields and basic neurosciences. For the first time, subarachnoid hemorrhage research is almost equally divided by early brain injury and cerebral vasospasm, mechanistic investigations and therapeutic approaches, demonstrating a translational feature of the future direction.
Contents:
A clinical review of cerebral vasospasm and delayed ischaemia following aneurysm rupture
New regulatory, signaling pathways, and sources of nitric oxide
Advances in experimental subarachnoid hemorrhage
Advances in treatment of cerebral vasospasm: an update
Roles of signal transduction mechanisms in cerebral vasospasm following subarachnoid hemorrhage: overview
Hypoperfusion in the acute phase of subarachnoid hemorrhage
Association of APOE polymorphism with the change of brain function in the early stage of aneurysmal subarachnoid hemorrhage
Apoptotic mechanisms for neuronal cells in early brain injury after subarachnoid hemorrhage
Early micro vascular changes after subarachnoid hemorrhage
Immunological response in early brain injury after SAH
Mechanisms of early brain injury after SAH: matrismetalloproteinase 9
Tyrosine phosphatase inhibition attenuates early brain injury after subarachnoid hemorrhage in rats
Protection of minocycline on early brain injury after subarachnoid hemorrhage in rats
Role of osteopontin in early brain injury after subarachnoid hemorrhage in rats
Matrix metalloproteinase 9 inhibition reduces early brain injury in cortex after subarachnoid hemorrhage
Nitric oxide synthase inhibitors and cerebral vasospasm
The role of nitric oxide donors in treating cerebral vasospasm after subarachnoid hemorrhage
Nitric oxide in early brain injury after subarachnoid hemorrhage
Nitric oxide related pathophysiological changes following subarachnoid hemorrhage
Endothelin-1(1-31) induces spreading depolarization in rats
The gamut of blood flow responses couples to spreading depolarization in rat and human brain: from hyperemia to prolonged ischemia
Cerebral microdialysis in acutely brain-injured patients with spreading depolarizations
Mitogen-activated protein kinases in cerebral vasospasm after subarachnoid hemorrhage: a review
Association of apolipoprotein E polymorphisms with cerebral vasospasm after spontaneous subarachnoid hemorrhage
Impact of subarachnoid hemorrhage on local and global calcium signaling in cerebral artery myocytes
Enhanced angiogenesis and astrocyte activation by ecdysterone treatment in a focal cerebral ischemia rat model
Bilirubin oxidation products seen post subarachnoid hemorrhage have greater effects on aged rat brain compared to young
Preliminary results of an ICP-controlled subarachnoid hemorrhage rabbit model for the study of delayed cerebral vasospasm
PKGIx inhibits the proliferation of cerebral arterial smooth muscle cell induced by oxyhemoglobin after subarachnoid hemorrhage
Characteristics of in vivo animal models of delayed cerebral vasospasm
Endothelin related pathophysiology in cerebral vasospasm: what happens to the cerebral vessels?
Expression and role of COMT in a rat subarachnoid hemorrhage model
Monitoring of the inflammatory response after aneurysmal subarachnoid hemorrhage in the clinical setting: review of literature and report of preliminary clinical experience
Perimesencephalic subarachnoid hemorrhage: risk factors, clinical presentations, and outcome
The relationship between IL-6 in CSF and occurrence of vasospasm after subarachnoid hemorrhage
Non-aneurysm subarachnoid hemorrhage in young adults
Cardiac damage after subarachnoid hemorrhage
Analysis on death-associated factors of patients with subarachnoid hemorrhage during hospitalization
Clinical study of changes of cerebral microcirculation in cerebral vasospasm after SAH
Effect of weekend admission on in-hospital mortality after subarachnoid hemorrhage in Chongquing China
The correlation between COMT gene polymorphism and early cerebral vasospasm after subarachnoid hemorrhage
Fever increased in-hospital mortality after subarachnoid hemorrhage
Subarachnoid hemorrhage in old patients in Chongquing China.
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