Bookedited by Ülo Langel.
Contents:
Classes and prediction of cell-penetrating peptides
Penetratin story: An overview
Testing membrane interactions of CPPs
Interactions of amphipathic CPPs with model membranes
NMR studies of three-dimensional structure and positioning of CPPs in membrane model systems
Measurements of the intracellular stability of CPPs
Tools for predicting binding and insertion of CPPs into lipid bilayers
Studies of proteoglycan involvement in CPP-mediated delivery
Uptake kinetics of cell-penetrating peptides
Thermodynamics of lipid interactions with cell-penetrating peptides
Calcium and membrane repair
Mapping of protein transduction pathways with fluorescent microscopy
Insight into cell-entry mechanisms of CPPs by electron microscopy
Toxicity methods for CPPs
Comparison of CPP uptake methods
Characterization of cellular internalization pathways for CPP-mediated oligonucleotide delivery
Mimicry of protein function with cell-penetrating peptides
Homeoprotein intercellular transfer, the hidden face of cell-penetrating peptides
Pharmacology, biodistribution, and efficacy of GPCR-based pepducins in disease models
Identification and characterization of tissue-specific protein transduction domains using peptide phage display
Applications of cell-penetrating peptides as signal transduction modulators for the selective induction of apoptosis
Splice redirection as a convenient assay to monitor CPP-on efficiency and mechanism
CPP-directed oligonucleotide exon skipping in animal models of Duchenne muscular dystrophy
PTD-DRBD siRNA delivery
A non-covalent peptide-based strategy for siRNA delivery
Application of pepfect peptides for the delivery of splice-correcting oligonucleotides
Internalization of nucleoside phosphates into live cells by complex formation with different CPPs and JBS-nucleoducin
Enhanced cellular delivery of cell-penetrating peptide-peptide nucleic acid conjugates by photochemical internalization
Identification of homing peptides using the in vivo phage display technology
Measuring the action of CPP-siRNA conjugates in the lung
Intracellular delivery of nanoparticles with CPPs
Multifunctional CPP polymer system for tumor-targeted pDNA and siRNA delivery
Cell-penetrating penta-peptides and bax-inhibiting peptides: Protocol for their application
Pair technology: Exon-specific rna-binding protein isolation in live cells
Quantitation of cellular and topical uptake of luciferin-oligoarginine conjugates
Industrial-scale manufacturing of a possible oligonucleotide cargo CPP-based drug
Application of a fusiogenic peptide GALA for intracellular delivery
Therapeutic applications of cell-penetrating peptides
Nonclinical and clinical experiences with CPP-based self-assembling peptide systems in topical drug development.