Bookedited by Anders Björklund, M. Angela Cenci.
Section I. Genetic and molecular mechanisms of neurodegeneration in PD -- Chapter 1. Identifying PD-causing genes and genetic susceptibility factors: Current approaches and future prospects / Thomas Gasser -- Chapter 2. The impact of genetic research on our understanding of Parkinson's disease / Ian Martin, Valina L. Dawson, Ted M. Dawson -- Chapter 3. Unravelling the role of defective genes / Mark R. Cookson -- Chapter 4. What causes the death of dopaminergic neurons in Parkinson's disease? / D. James Surmeier, Jaime N. Guzman, Javier Sanchez-Padilla, Joshua A. Goldberg -- Chapter 5. Intracellular signalling pathways in dopamine cell death and axonal degeneration / Robert E. Burke -- Chapter 6. Control of mitochondrial integrity in Parkinson's disease / Cristofol Vives-Bauza, Maja Tocilescu, Rosa L.A. deVries, Dana M. Alessi, Vernice Jackson-Lewis, Serge Przedborski -- Chapter 7. Role of post-translational modifications in modulating the structure, function and toxicity of α-synuclein: Implications for Parkinson's disease pathogenesis and therapies / Abid Oueslati, Margot Fournier, Hilal A. Lashuel -- Section II. Cellular and system-level pathophysiology of the basal ganglia in PD -- Chapter 8. The role of dopamine in modulating the structure and function of striatal circuits / D. James Surmeier, Weixing Shen, Michelle Day, Tracy Gertler, Savio Chan, Xianyong Tian, Joshua L. Plotkin -- Chapter 9. Assemblies of glutamate receptor subunits with post-synaptic density proteins and their alterations in Parkinson's disease / Fabrizio Gardoni, Veronica Ghiglieri, Monica di Luca, Paolo Calabresi -- Chapter 10. Pathophysiological roles for purines: Adenosine, caffeine and urate / Micaela Morelli, Anna R. Carta, Anil Kachroo, Michael A. Schwarzschild -- Chapter 11. Maladaptive striatal plasticity in l-DOPA-induced dyskinesia / M. Angela Cenci, Christine Konradi -- Chapter 12. Effects of GPi and STN inactivation on physiological, motor, cognitive and motivational processes in animal models of Parkinson's disease / Christelle Baunez, Paolo Gubellini -- Chapter 13. Computational physiology of the basal ganglia in Parkinson's disease / Michal Rivlin-Etzion, Shlomo Elias, Gali Heimer, Hagai Bergman -- Chapter 14. Neurocomputational models of motor and cognitive deficits in Parkinson's disease / Thomas V. Wiecki, Michael J. Frank.