Bookedited by Rony Seger.
Contents:
The MAP kinase signaling cascades : A system of hundreds of components regulates a diverse array of physiological functions
Determination of ERK activity: Anti-phospho-ERK antibodies and in vitro phosphorylation
Activation of SAPK/JNKs in vitro
Activation of p38 and determination of its activity
Activity assays for extracellular signal-regulated kinase 5
Use of inhibitors in the study of MAP kinases
MAP kinase activation by receptor tyrosine kinases : in control of cell migration
Activation of ras and rho GTPases and MAP kinases by G-protein-coupled receptors
Regulation of MAP kinase signaling by calcium
Identification of novel substrates of MAP kinase cascades using bioengineered kinases that uniquely utilize analogs of ATP to phosphorylate substrates
ERK-MAP kinase signaling in the cytoplasm
Lentiviral vectors to study the differential function of ERK1 and ERK2 MAP kinases
Structural studies of MAP kinase cascade components
Analysis of MAP kinases by hydrogen exchange mass spectrometry
A "Molecular evolution" approach for isolation of intrinsically active (MEK-independent) MAP kinases
Reconstitution of the nuclear transport of the MAP kinase ERK2
Localization and trafficking of fluorescently tagged ERK1 and ERK2
Studying the regulation of MAP kinase by MAP kinase phosphatases in vitro and in cell systems
Proteomic analysis of scaffold proteins in the ERK cascade
Analysis of ERKs' dimerization by electrophoresis
MAP kinase: SUMO pathway interactions
Computational modelling of kinase signalling cascades
Analysis of mitogen-activated protein kinase activity in yeast
Detection of RTK pathway activation in drosophila using anti-dpERK immunofluorescence staining
Studying MAP kinase pathways during early development of xenopus laevis
Deciphering signaling pathways in vivo : The ras/raf/MEK/ERK cascade
Mutational and functional analysis in human ras/MAP kinase genetic syndromes
Implication of the ERK pathway on the post-transcriptional regulation of VEGF mRNA stability
Studies on MAP kinase signaling in the immune system
Methods to study MAP kinase signalling in the central nervous system
MAP kinase regulation of the mitotic spindle checkpoint
Using high-content microscopy to study gonadotrophin-releasing hormone regulation of ERK.