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  • Book
    senior editors, J. Larry Jameson, Leslie J. De Groot ; section editors, David de Kretser ... [et al.].
    Status: Not Checked Out
    V. 1 -- Endocrinology: impact on science and medicine -- Control of hormone gene expression -- Control of hormone secretion -- Insulin and growth factor signaling pathways -- Hormone signaling via G protein-coupled receptors -- Nuclear receptors: structure, function, and coregulators -- Applications of genetics in endocrinology -- Development of the pituitary -- Prolactin -- Adrenocorticotropic hormone -- Endocrine rhythms, the sleep-wake cycle, and biological clocks -- Hypothalamic syndromes -- Hypopituitarism and growth hormone deficiency -- Acromegaly -- Cushing's syndrome -- Clinically nonfunctioning sellar masses -- TSH-producing adenomas -- Disorders of prolactin secretion and prolactinomas -- Pituitary surgery -- Evaluation and management of childhood hypothalamic and pituitary tumors -- Vasopressin, diabetes insipidus, and the syndrome of inappropriate antidiuretic hormone secretion -- The pineal gland and melatonin -- Regulation of growth hormone and action (secretagogues) -- Insulin-like growth factor-1 and its binding proteins -- Somatic growth and maturation -- Growth hormone deficiency in children -- Appetite regulation and thermogenesis -- Obesity: the problem and its management -- Genetic syndromes associated with obesity -- Anorexia nervosa, bulimia nervosa, and other eating disorders -- Development of the endocrine pancreas -- Biosynthesis, processing, and secretion of the islet hormones: insulin, islet amyloid polypeptide (amylin), glucagon, somatostatin, and pancreatic polypeptide -- Insulin secretion -- The mechanisms of insulin action -- Glucagon and the glucagon-like peptides -- Regulation of intermediatory metabolism during fasting and feeding -- Role of the adipocyte in metabolism and endocrine function -- Lipodystrophy syndromes -- Classification and diagnosis of diabetes mellitus -- Type 1 (insulin-dependent) diabetes mellitus: etiology, pathogenesis, prediction, and prevention -- Type 2 diabetes mellitus: etiology, pathogenesis, and natural history -- Lipoprotein metabolism and the treatment of lipid disorders -- Hyperglycemia secondary to nondiabetic conditions and therapies -- The metabolic syndrome -- Treatment of type 1 diabetes mellitus in adults -- Ketoacidosis and hyperosmolar coma -- Hypoglycemia and hypoglycemic syndromes -- Management of type 2 diabetes mellitus -- Management of diabetes mellitus in children -- Pancreatic and islet transplantation -- Diabetes control, long-term complications, and large vessel disease -- Diabetic eye disease -- Diabetes mellitus: neuropathy -- Diabetic nephropathy -- Diabetic foot and vascular complications -- Parathyroid hormone and parathyroid hormone-related peptide in the regulation of calcium homeostasis and bone development -- Calcitonin -- Vitamin D: from photosynthesis, metabolism, and action to clinical applications -- Bone development and remodeling -- Calcium regulation, calcium homeostasis, and genetic disorders of calcium metabolism -- Genetic disorders of phosphate homeostasis -- Primary hyperparathyroidism -- Malignancy-associated hypercalcemia and medical management -- Surgical management of hyperparathyroidism -- Pseudohypoparpathyroidism, Albright's hereditary osteodystrophy, and progressive osseous heteroplasia: disorders caused by inactivating GNAS mutations -- Genetic defects in vitamin D metabolism and action -- Hereditary disorders of the skeleton -- Bone density and imaging of osteoporosis -- Chronic kidney disease mineral and bone disorder -- Disorders of calcification: osteomalacia and rickets -- Paget's disease of bone -- V. 2 -- Anatomy and development of the thyroid -- Thyroid-stimulating hormone: physiology and secretion -- Thyroid regulatory factors -- Thyroid hormone metabolism -- Mechanisms of thyroid hormone action -- Thyroid function testing -- Thyroid imaging -- Autoimmune thyroid disease -- Graves' disease -- Graves' ophthalmopathy -- Autonomously functioning thyroid nodules and other causes of thyrotoxicosis -- Chronic (Hashimoto's) thyroiditis -- Subacute and Riedel's thyroiditis -- Hypothyroidism and myxedema coma -- Nonthyroidal illness syndrome: a form of hypothyroidism -- Multinodular goiter -- Iodine deficiency disorders -- Thyroid neoplasia -- Medullary thyroid carcinoma and multiple endocrine neoplasia type 2 -- Thyroid-stimulating hormone receptor mutations -- Genetic defects in thyroid hormone synthesis and action -- Thyroid hormone binding and variants of transport proteins -- Resistance to thyroid hormone -- Surgery of the thyroid -- The principles, enzymes, and pathways of human steroidogenesis -- Glucocorticoid action: physiology -- Glucocorticoid receptors: their mechanisms of action and glucocorticoid resistance -- Aldosterone: secretion and action -- Glucocorticoid therapy -- Adrenal insufficiency -- Adrenal causes of hypercortisolism -- Defects of adrenal steroidogenesis -- Adrenarche and adrenopause -- Adrenal gland imaging -- Adrenocortical carcinoma -- Primary mineralocorticoid excess syndromes and hypertension -- Mineralocorticoid deficiency -- Pheochromocytoma -- Adrenal surgery -- Hormones of the cardiovascular system -- Hyponatremia and hypernatremia -- Orthostatic hypotension and orthostatic intolerance -- Endocrine aspects of critical care medicine -- Gonadotropin-releasing hormones -- Gonadal peptides: inhibins, activins, follistatin, Müllerian-inhibiting substance (antimüllerian hormone) -- Gonadotropins-regulation of synthesis and secretion -- Genetic basis of gonadal and genital development -- Diagnosis and treatment of disorders of sexual development -- Endocrinology of sexual maturation and puberty -- Precocious puberty -- Delayed puberty -- Hormonal control of breast development -- The endocrinology of sexual behavior and gender identity -- Folliculogenesis, ovulation, and luteogenesis -- Ovarian hormone synthesis -- Estrogen and progesterone action -- Hormonal regulation of the menstrual cycle, mechanisms of ovulation, premenstrual syndromes -- Amenorrhea, anovulation, and dysfunctional uterine bleeding -- Endometriosis -- Female subfertility: evaluation and management -- Hyperandrogenism, hirsutism, and the polycystic ovary syndrome -- Ovulation induction and assisted reproduction -- Contraception -- Menopause -- Functional morphology of the testis -- Androgen physiology, pharmacology, and abuse -- Testicular dysgenesis syndrome, cryptorchidism, hypospadias, and testicular tumors -- Androgen deficiency disorders -- Gynecomastia -- Clinical management of male infertility -- Male contraception -- Endocrinology of the prostate -- The endocrinology of human pregnancy and parturition -- Fetal and neonatal endocrinology -- Diabetes mellitus and pregnancy -- Diagnosis and treatment of thyroid disease during pregnancy -- Hormonal changes and endocrine testing in pregnancy -- Autoimmune polyglandular syndromes -- Multiple endocrine neoplasia type 1 -- Multiple endocrine neoplasia type 2 -- Gastrointestinal hormones and tumor syndromes -- Carcinoid syndrome -- Ectopic hormone syndromes -- Endocrine testing.