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  • Book
    Haiyong Han, Paul Grippo, editors.
    Digital : Springer2010
    1. Drug evaluations in pancreatic cancer culture systems -- 2. Mouse xenograft models for drug discovery in pancreatic cancer -- 3. Flourescent metastatic mouse models of pancreatic cancer for drug discovery -- 4. A new preclinical paradigm for pancreas cancer -- 5. Zebrafish as a biological system for identifying and validating therapeutic targets and compounds -- 6. Gene expression arrays in pancreatic cancer drug discovery research -- 7. Using array comparative genomic hybridization of pancreatic cancer samples to map interesting regions for target gene identification -- 8. The application of high-throughput RNAi in pancreatic cancer target discovery and drug development -- 9. MicroRNA a profiling and its application in drug discovery in pancreatic cancer -- 10. Methylation detection and epigenomics in pancreatic cancer -- 11. Tissue microarray applications in drug discovery for pancreatic cancer -- 12. Proteomic analysis of blood and pancreatic juice -- 13. Applications of antibody-lectin sandwich arrays (ALSA) to pancreatic cancer diagnostics and drug discovery -- 14. The development of pharmacodynamic endpoint models for evaluation of therapeutic in pancreatic cancer -- Index.