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  • Book
    Holger Halthoff (ed.).
    Digital : Springer2009
    Print2009
    The role of TNF in cancer / Harald Wajant -- Many checkpoints on the road to cell death: regulation of Fas-FasL interactions and Fas signaling in peripheral immune responses / Madhu Ramaswamy ... [et al.] -- FasL expression and reverse signaling / M. Lettau ... [et al.] -- Impact of TNF-R1 and CD95 internalization on apoptotic and antiapoptotic signaling / Stefan Schütze and Wulf Schneider-Brachert -- Ubiquitination and TNFR1 signaling / Ken-ichi Fujita and Srinivasa M. Srinivasula -- From biochemical principles of apoptosis induction by TRAIL to application in tumour therapy / Stefanie M. Cordier, Kerstin Papenfuss, and Henning Walczak -- Therapeutic targeting of TWEAK/Fn14 in cancer: exploiting the intrinsic tumor cell killing capacity of the pathway / Jennifer S. Michaelson and Linda C. Burkly -- APRIL in B-cell malignancies and autoimmunity / Fiona C. Kimberly, Jan Paul Medema, and Michael Hahne -- Autophagy in cancer and chemotherapy / Shida Yousefi and Hans-Uwe Simon -- Glucocorticoid-mediated apoptosis resistance of solid tumors / Ingrid Herr, Markus W. Büchler, and Jürgen Mattern -- Targeting death-receptors in radiation therapy / Olivier Niemöller and Claus Belka -- Death ligands designed to kill: development and application of targeted cancer therapeutics based on proapoptotic TNF family ligands / Jeannette Gerspach, Harald Wajant, and Klaus Pfizenmaier.