Bookedited by Donna L. Mendrick, William B. Mattes.
Contents:
Toxicogenomics and classical toxicology, how to improve prediction and mechanistic understanding of human toxicity / Donna L. Mendrick
Use of traditional endpoints and gene dysregulation to understand mechanisms of toxicity / Wayne R. Buck, Jeffrey F. Waring, Eric A. Blomme
Quality control of microarray assays for toxicogenomic and in vitro diagnostic applications / Karol L. Thompson and Joseph Hackett
Role of statistics in toxicogenomics / Michael Elashoff
Predictive toxicogenomics in preclinical discovery / Scott A. Barros and Rory B. Martin
In vivo predictive toxicogenomics / Mark W. Porter
Bioinformatics, databasing and gene annotation / Lyle D. Burgoon and Timothy R. Zacharewski
Microarray probe mapping and annotation in cross - species comparative toxicogenomics / John N Calley, William B Mattes, Timothy P. Ryan
Toxicogenomics in biomarker discovery
Marc F. DeCristofaro, Kellye K. Daniels
From pharmacogenomics to translational biomarkers / Donna L. Mendrick
Public consortium efforts in toxicogenomics / William B. Mattes
Applications of toxicogenomics to nonclinical drug development / Frank D. Sistare, Joseph J. DeGeorge.