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  • Database
    Summary: A diagnostic decision support system designed by clinicians to aid medical professionals in the diagnosis of visually identifiable diseases. Provides instant access to specialist knowledge at the point of care, merging medical images with concise clinical text. Includes more than 18,000 images representing over 1,000 visually identifiable diseases, drug reactions, and infections. As the clinician enters specific patient findings, VisualDx creates a visual differential diagnosis. The clinician enters symptoms and other clinical findings, such as lesion type, body location, medical history, medications, etc. With each entry, the system builds and refines the differential, never eliminating a diagnostic possibility but ranking each one by relevance to the patient findings. VisualDx displays images and key clinical information on all relevant diagnoses for a quick side-by-side comparison to the patient. Intended not to substitute, but to complement traditional medical information sources.
    Digital Access VisualDx Database
  • Article
    Badley RA.
    Biochim Biophys Acta. 1975 Feb 27;379(2):517-28.
    Quenching of the tryptophan fluorescence of pig serum HDL3 and LDL2 lipoproteins by iodide and succinimide has been used to estimate the accessibility of the fluorophores to the solvent and, by inference, the location of the protein in the macromolecular complexes. At least 80% of the protein is thought to be located at or near the surface in both lipoproteins but its accessibility is hindered especially in LDL2. A difference in surface topography in the two lipoproteins is suggested with the protein in LDL2 more buried in lipid and further away from the charged phospholipid polar groups than in HDL3. A refined treatment of the quenching data has been developed to take account of the heterogeneity of quenching sites found in the lipoproteins.
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