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    Summary: AbMiner is a tool that allows users to search for appropriate, commercially available antibodies (>600) for research purposes, and to match each antibody to its respective genomic identifiers. The unique feature of this antibody collection is that all antibodies are screened by Western blot. The sample used for antibody screening was a pool of the NCI-60 cancer cell lines, comprised of 60 different cell lines from 9 different tissues of origin. Besides results, AbMiner also includes the dilutions used and pertinent vendor information for all antibodies. The target antigen for each antibody was translated to the encoding gene symbol using MatchMiner. Other identifiers include gene name, HUGO status, UniGene Cluster ID, RefSeq for protein and mRNA, and Entrez Gene Ids. These identifiers are updated periodically as new information becomes available. Users can search AbMIner by any of the identifiers and easily navigate between antibody, protein, mRNA, and gene.
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  • Article
    Myers JD, Spencer HC, Watts JC, Gregg MB, Stewart JA, Troupin RH, Thomas ED.
    Ann Intern Med. 1975 Feb;82(2):181-8.
    Thirty-three of 85 patients undergoing marrow transplantation between 1969 and 1973 developed interstitial pneumonia; 23 died. The clinical syndrome consisted of tachypnea, cough, fever, rales, and hypoxemia; the radiologic findings were variable. The development of interstitial pneumonia was significantly associated with graft-versus-host disease and allogenic grafting; patients with isogenic grafts were relatively spared. The increased attack rate between 1969-71 (20%) and 1972-73 (49%) was not fully explained by improved long-term survival, by an increased proportion of allogenic transplants, or by an increased incidence of graft-versus-host disease. Intranuclear inclusions typical of cytomegalovirus were identified in 9 of 17 autopsy-confirmed cases, and patients whose marrow donors had positive cytomegalovirus antibody titers developed interstitial pneumonia more often than patients whose donor had negative titers. Interstitial pneumonia is an important cause of morbidity and mortality after human marrow transplantation. No effective treatment is presently available.
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