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- ArticleKorkuschko OW, Kotko DN.Aktuelle Gerontol. 1976 Jun;6(6):305-10.For understanding age peculiarities of gastric secretory function in aging.tory function in aging.tory function regulation, the investigation of nervous influences on gastric secretion is of importance. With this end in view the unconditioned reflex stimulus- the tube with rubber balloon, containing 10 ml of water and conditioned reflex stimulus - food stimulus were employed. The fractional gastric intubation was carried out. The gastric secretion in response to mechanical stimulus was investigated in 125 persons aged 60-89 and in 40 persons aged 20-25 (control group). In response to conditioned reflex stimulus it was studied in 30 persons aged 60-89 and 10 persons aged 20-35 (control group). With aging the response of gastric glands to unconditioned and conditioned stimuli was found to decrease. The amount of secretion, hydrochloric acid, pepsin, and gastromuco-protein were decreased, the secretory effect being more slowly developed, the torpid secretion type being observed. The above facts testify to changes of nervous regulation of gastric secre