Bookguest editors: Etelka Farkas (University of Debrecen, Faculty of Science and Technology,
... Show More Department of Inorganic and Analytical Chemistry, Debrecen, Hungary), Celine J. Marmion (RCSI University of Medicine and Health Sciences, Department of Chemistry, Dublin, Ireland).
Summary: "In this volume the authors promote, endorse and stimulate research in the vibrant field of biological inorganic chemistry. They provide an overview of metallodrugs which have been rationally designed to target specific biomolecules in the human body with a view to generating targeted drugs or prodrugs with widespread biomedical applications. The volume focuses on recent trends and advances in relation to targeted metallodrugs as anti-cancer, anti-microbial and anti-viral agents with an emphasis on their design, development and mode of action. It also include recent advances in the use of nanoparticles and nanoclusters as important chaperones to deliver metallodrugs to their sites of action"-- Provided by publisher.
Contents:
Metal-Based Prodrugs Activated by Cancer-Specific Stimuli
Light-Activated Drugs for Photodynamic and Photoactivated Therapy
Mitochondria as a Metallo-Drug Target for Therapeutic Purposes
Transition Metal-Based Anti-Viral Agents against SARS-CoV-2 and Other Pathogenic
Exploiting the Chemical Diversity of Metal Compounds as a Source of Novel Anti-COVID-19 Drugs
Evaluating the Potential of Novel Metal-Based Drugs for Treating Drug Resistant Bacteria
Prospective Metallo-Drugs Including Bioactive Compounds: Selection of Co-Ligands to Tune Biological Activity against Neglected Tropical Diseases
Challenges in Targeting Cyanide Poisoning: Advantages in Exploiting Metal Complexes in Its Treatment
Advanced Microscopy Methods for Elucidating the Localization of Metal Complexes in Cancer Cells
Metalloproteomics: A Powerful Technique for Metals in Medicine
Metal-Based Nanoclusters for Biomedical Applications Radiometals in Molecular Imaging and Therapy.