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  • Article
    Hermann JM, Hammes HP, Rami-Merhar B, Rosenbauer J, Schütt M, Siegel E, Holl RW, DPV Initiative the German BMBF Competence Network Diabetes Mellitus.
    PLoS One. 2014;9(3):e91137.
    OBJECTIVE: This study aimed to analyze the effect of HbA1c variability on the occurrence of diabetic retinopathy in type 1 diabetes patients.
    PATIENTS AND METHODS: 35,891 patients with childhood, adolescent or adult onset of type 1 diabetes from a large multicentre survey, the German/Austrian prospective documentation system (DPV), were analysed. Cox proportional hazard models were used to examine whether intra-individual HbA1c variability expressed as variation coefficient is an independent risk factor for the occurrence of diabetic retinopathy.
    RESULTS: Kaplan-Meier curves stratified by median HbA1c and variation coefficient revealed that retinopathy-free survival probability is lower when both median HbA1c and HbA1c variability are above the 50th percentile. Cox regression models confirmed this finding: After adjustment for age at diabetes onset, gender and median HbA1c, HbA1c variability was independently associated with the occurrence of diabetic retinopathy. Time-covariate interactions used to model non-proportionality indicated an effect decreasing with duration of diabetes for both median HbA1c and HbA1c variability. Predictive accuracy increased significantly when adding HbA1c variability to the Cox regression model.
    CONCLUSIONS: In patients with type 1 diabetes, HbA1c variability adds to the risk of diabetic retinopathy independently of average metabolic control.
    Digital Access Access Options
  • Book
    Kai-Fu Lee.
    Summary: The United States has long been the leader in Artificial Intelligence. But Dr. Kai-Fu Lee--one of the world's most respected experts on AI--reveals that China has caught up to the US at an astonishingly rapid pace. As Sino-American competition in AI heats up, Lee envisions China and the US forming a powerful duopoly in AI. He outlines the upheaval of traditional jobs, how the suddenly unemployed will find new ways of making their lives meaningful, and how the Chinese and American governments will have to cope with the changing economic landscape. "Kai-Fu Lee--one of the world's most respected experts on AI and China--reveals that China has suddenly caught up to the United States at an astonishingly rapid and unexpected pace. In AI Superpowers, Kai-Fu Lee argues powerfully that because of the unprecedented developments in artificial intelligence, dramatic changes will be happening much sooner than many of us have expected. Indeed, as the U.S.-China competition in AI begins to heat up, Lee urges America and China to both accept and embrace the great responsibilities that come with significant technological power. Most experts already say that AI will have a devastating impact on blue-collar jobs. But Lee predicts that Chinese and American AI will have a strong impact on white-collar jobs as well. Is universal basic income the solution? In Lee's opinion, probably not. But he provides a clear description of which jobs will be affected and how soon, which jobs can be enhanced with AI, and, most important, how we can provide solutions to some of the most profound changes in human history that are coming soon."--Jacket.

    Contents:
    China's Sputnik moment
    Copycats in the Coliseum
    China's alternate Internet universe
    A tale of two countries
    The four waves of AI
    Utopia, dystopia, and the real AI crisis
    The wisdom of cancer
    A blueprint for human co-existence with AI
    Our global AI story.
    Print Access Request
    Location
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    Books: General Collection (Downstairs)
    HC79.I55 L435 2018
    1