Today's Hours: Closed
Lane Medical Library

Search

Filter Results

Did You Mean:

Search Results

Sort by
relevance
  • Article
    Kharduit PB, Dutta K, Lyngdoh CJ, Bhattacharyya P, Lyngdoh V, Khyriem AB, Devi SK.
    Cureus. 2024 Jun;16(6):e63428.
    Background Central line-associated bloodstream infections (CLABSIs) are significant healthcare-associated infections that increase morbidity, mortality, and healthcare costs. This study aims to analyze the frequency, microbiology, risk factors, and outcomes of CLABSI in an adult intensive care unit. Methods We conducted a hospital-based, prospective surveillance study in the critical care unit of a tertiary care hospital. We included patients with a central line (CL) from admission until discharge or line removal. Data collection focused on patient demographics, comorbidities, CL insertion site, and CLABSI rates. The incidence of CLABSI was calculated per 1,000 CL-days, and statistical analysis was performed using the Chi-square test. Results Of the 169 patients enrolled, 123 episodes of bloodstream infections were recorded, 56 (45.5%) of which were CLABSIs. The organisms most frequently isolated were Klebsiella pneumoniae (n = 14; 24.6%), Enterobacter cloacae complex (n = 11; 19.3%), Klebsiella species (n = 7; 12.28%), and Acinetobacter baumannii (n = 7; 12.28%). The overall CLABSI rate was 24.70 per 1,000 CL-days. No significant association was found between CLABSI and patient age, gender, or the site of CL insertion. However, a significant relationship was observed between CLABSI and the presence of comorbid conditions (p = 0.001). The study also noted a high rate of antibiotic resistance among the isolated pathogens. Conclusions Our results emphasize the need for stringent infection control measures and suggest that comorbid conditions significantly increase the risk of CLABSI. Addressing antibiotic resistance and implementing effective prevention strategies are essential for reducing the burden of CLABSIs.
    Digital Access Access Options
  • Article
    Dai H, Cao F, Chen X, Zhang M, Ahmed IM, Chen ZH, Li C, Zhang G, Wu F.
    PLoS One. 2013;8(5):e63428.
    Aluminum (Al) toxicity is a major limiting factor for plant production in acid soils. Wild barley germplasm is rich in genetic diversity and may provide elite genes for crop Al tolerance improvement. The hydroponic-experiments were performed to compare proteomic and transcriptional characteristics of two contrasting Tibetan wild barley genotypes Al- resistant/tolerant XZ16 and Al-sensitive XZ61 as well as Al-resistant cv. Dayton. Results showed that XZ16 had less Al uptake and translocation than XZ61 and Dayton under Al stress. Thirty-five Al-tolerance/resistance-associated proteins were identified and categorized mainly in metabolism, energy, cell growth/division, protein biosynthesis, protein destination/storage, transporter, signal transduction, disease/defense, etc. Among them, 30 were mapped on barley genome, with 16 proteins being exclusively up-regulated by Al stress in XZ16, including 4 proteins (S-adenosylmethionine-synthase 3, ATP synthase beta subunit, triosephosphate isomerase, Bp2A) specifically expressed in XZ16 but not Dayton. The findings highlighted the significance of specific-proteins associated with Al tolerance, and verified Tibetan wild barley as a novel genetic resource for Al tolerance.
    Digital Access Access Options
  • Article
    Centers for Medicare & Medicaid Services (CMS), Department of Health and Human Services (HHS).
    Fed Regist. 2018 Dec 10;83(236):63419-28.
    This final rule adopts the HHS-operated risk adjustment methodology for the 2018 benefit year. In February 2018, a district court vacated the use of statewide average premium in the HHS-operated risk adjustment methodology for the 2014 through 2018 benefit years. Following review of all submitted comments to the proposed rule, HHS is adopting for the 2018 benefit year an HHS-operated risk adjustment methodology that utilizes the statewide average premium and is operated in a budget-neutral manner, as established in the final rules published in the March 23, 2012 and the December 22, 2016 editions of the Federal Register.
    Digital Access Access Options
  • Book
    Allison J. Applebaum.
    Summary: Compassionate, groundbreaking, and urgently needed, Stand By Me provides caregivers with new ways to juggle the responsibilities and emotional ups and downs of caregiving.As the founder of the only devoted Caregivers Clinic in the country, clinical psychologist Dr. Allison Applebaum is no stranger to the intensity of being an unpaid, untrained family caregiver. She also understands that it is often the strength and well-being of these very caregivers--the parents, children, partners, siblings, and friends of patients--that are the true linchpin determining each patient's illness experience. This book puts the practical tools and transformative support of the Caregivers Clinic in your hands, empowering you to provide your loved one with the best quality of life and care possible, while promoting your own wellbeing. The book covers crucial topics including: -Getting the most from any healthcare system -Productive advance care planning -Navigating changing roles and relationship dynamics -Finding meaning and purpose in the caregiving experience Stand By Me draws on a decade of clinical and research experience as well as Dr. Applebaum's personal journey as the primary caregiver for her own father, legendary composer Stanley Applebaum, at the end of his life. Dr. Applebaum recognizes caregivers for who they truly are: invaluable healthcare team members. Offering critical insight and takeaways, Stand By Me is an essential resource throughout your caregiving journey.
    Digital Access OverDrive. 2024
    Limited to 1 simultaneous user