Books by Subject

Research

  • Print
    edited by Michael E. Hochman.
    Status: Not Checked Out
    Sect. 1: Preventive medicine -- Preventing diabetes: the diabetes prevention program -- A comparison of different dieting strategies -- Aspirin for the primary prevention of cardiovascular disease: the physician's health study and the women's health study -- Postmenopausal hormone therapy: the women's health initiative -- The European randomized study of screening for prostate cancer (ERSPC) -- The cochrane review of screening mammography -- The human papillomavirus vaccine: the future II trial -- Sect. 2: Internal medicine -- Arrhythmia suppression following myocardial infarction: the CASt trial -- Choosing first-line therapy for hypertension: the ALLHAT trial -- Statins in healthy patients with an elevated c-reactive protein: the JUPITER trial -- Rate control versus rhythm control for atrial fibrillation: the AFFIRM trial -- Lenient versus strict heart rate control for atrial fibrillation: the RACC II trial. -- Beta blockers for systolic heart failure: the MERIT-HF trial -- Initial treatment of stable coronary artery disease: the COURAGE trial -- Treating elevated blood sugar levels in patients with type 2 diabetes: the United Kingdom prospective diabetes study (UKPDS) -- Intensive versus conservative blood sugar for patients with type 2 diabetes: the ACCORD trial -- The African American heart failure trial (A-HeFT) -- Early versus delayed antiretroviral therapy for patients with HIV: the NA-ACCORD study -- Early versus late initiation of dialysis: the IDEAL trial -- Early goal-directed therapy in sepsis -- Red cell transfusion in critically ill patients: the TRICC trial -- Pulmonary artery catheters in critically ill patients -- Step-up versus step-down therapy for dyspepsia: the DIAMOND trial -- Opioids for chronic noncancer pain -- Sect. 3: Surgery -- Perioperative beta blockers in noncardiac surgery: the POISE trial -- Cardiac stents versus coronary artery bypass surgery for severe coronary artery disease: the SYNTAX trial -- Carotid endarterectomy for asymptomatic carotid stenosis: the ACST trial -- A trial of arthroscopic knee surgery -- Surgery versus rehabilitation for chronic low back pain: the MRC spine stabilization trial -- Mastectomy versus lumpectomy for invasive breast cancer: the B-06 trial -- Long-term impact of bariatric surgery: the Swedish obese subjects study -- Sect. 4: Obstetrics -- The Canadian multicenter post-term pregnancy trial (CMPPT) -- Antepartum glucocorticoids in premature labor -- Sect. 5: Pediatrics -- Treatment of acute otitis media in children -- A trial of early ear tube placement in children with persistent otitis media -- Inhaled corticosteroids for mild persistent asthma: the START trial -- The multimodal treatment study of children with attention deficit/hyperactivity disorder (MTA) -- Measles, mumps, and rubella vaccination and autism -- Sect. 6: Radiology -- Magnetic resonance imaging for low back pain -- Screening for coronary artery disease in asymptomatic patients with diabetes: the DIAD study -- Diagnosing acute pulmonary embolism: the Christopher study -- Identifying children with low-risk head injuries who do not require computed tomography -- Sect. 7: Neurology and psychiatry -- Thrombolysis 3 to 4.5 hours after an acute ischemic stroke: the ECASS III trial -- Initial treatment of depression -- Behavioral versus pharmacological treatment for insomnia in the elderly -- Sect. 8: Systems-based practice -- The group health medical home demonstration -- A program to improve care coordination at hospital discharge: project RED -- Reducing catheter-related blood stream infections in the intensive care unit: the keystone ICU project -- Early palliative care in non-small-cell lung cancer -- Directly observed therapy for the treatment of tuberculosis in Baltimore.
  • Digital
    edited by SreyRam Kuy, Rachel J. Kwon, Miguel A. Burch.
    Oxford Medicine Online2018
  • Digital
    This annual report details NIH-supported and -conducted Alzheimer's disease research initiatives, objectives, and advances during calendar year 2014 and early 2015. New findings and investments described in this report are organized in categories determined by the Common Alzheimer Disease Research Ontology (CADRO) of the International Alzheimer's Disease Research Portfolio (IADRP).
  • Digital
    edited by Mohit Bhandari, Bernd Robioneck ; associate editor, Emil Schemitsch ; managing editor, Sheila Sprague ; with contributions by Volker Alt ... [et al.].
    Thieme MedOne Education2012
    Thieme MedOne Plastic Surgery2012
    1. Factorial Randomized Trials -- Summary -- Introduction -- Randomized clinical trial design strategies with multiple interventions -- Selecting a factorial randomized design -- Conclusion -- 2. Expertise-based randomized trials -- Summary -- Introduction -- Conventional RCT design -- Expertise-based RCT design -- Challenges of expertise-based RCTs -- Independent assessor -- Balanced and consecutive or random contributions to screening pool -- Perceived equivalence between practices -- Conclusion -- 3. Randomization systems and technology -- Summary -- Introduction -- Methods of patient allocation -- Other considerations -- Conclusion -- 4. Blinding and concealment -- Summary -- Introduction -- Concealment -- Blinding -- Conclusion -- 5. Composite outcome in orthopaedics: understanding the concepts -- Summary -- Introduction -- Rationale for use of a composite outcome -- Limitations of using composite outcomes -- Guidelines for creating a "good" composite outcome -- Reporting and interpreting composite outcomes -- Conclusion -- 6. Adjudication of outcomes-systems and approaches -- Summary -- Introduction -- Importance of adjudication -- Process of adjudication -- Existing methods of adjudication -- Web-based adjudication -- Conclusion -- 7. Subgroup analyses -- Summary -- Introduction -- Subgroup analysis defined -- Design of a subgroup analysis -- Reporting -- Interpretation -- Conclusion -- 8. Trial management-advance concepts and systems -- Summary -- Introduction -- Phases of clinical trials -- Common considerations in conducting a clinical trial -- Trial committees -- The search for funding -- Conclusion 9. Case-control studies -- Summary -- Introduction -- Definition of a case-control study -- Conclusion -- 10. Cohort studies -- Summary -- Introduction -- Cohort studies in the hierarchy of evidence -- Types of cohort study designs -- Methods for reducing confounding and assessing causality -- A checklist to evaluate or improve the strength of evidence -- Conclusion --; 11. Survey Design -- Summary -- Introduction -- Identifying a research question -- Survey development -- Survey design -- Using exiting surveys -- survey validataion -- Pilot testing -- Survey administration -- Ethical considerations -- Financial considerations -- Conclusion -- 12. Qualitative studies -- Summary -- Introduction -- What is qualitative research? -- How is qualitative research done? -- Conclusion -- 13. Economic analysis -- Summary -- Introduction -- Theoretical background -- Conducting health economics studies -- Conclusion -- 14. Literature searches -- Summary -- Introduction -- When to conduct a literature search -- How to conduct a literature search -- Study selection -- Assessing methodological quality of studies -- Data extraction and analysis -- Conclusion -- 15. Summary -- Introduction -- the P value does not assess the magnitude of a treatment effect -- The challenge of comparing results across studies -- Types of effect sizes -- Confidence intervals for effect sizes -- Use of effect size in meta-analysis -- Conclusion -- 16. Fixed effects versus random effects -- Summary -- Introduction -- the data pool: fixed effects versus random effects -- Deciding which model to use -- Conclusion -- 17. Heterogeneity -- Summary -- Introduction -- Heterogeneity defined -- Identifying heterogeneity -- Dealing with heterogeneity -- Conclusion -- 18. Uncovering publicatiion bias -- Summary -- Introduction -- Authors and publication bias -- Detecting and adjusting for publication bias -- Minimizing the effect of publication bias -- A possible solution: trial registers -- Conclusion -- 19. Statiecal pooling - programs and systems -- Summary -- Introduction -- Selectin the appropriate programs and systems: factors to consider --Review of programs and systems -- Types of programs and systems -- Recommendations -- Conclusion -- 20. Meta-analysis of observational studies -- Summary -- Introduction -- The observational data dilemma -- Conclusion -- 21. Meta-regression -- Summary -- Introduction -- Heterogeneity and meta-regression -- Meta-regression mechanics -- Interpreting a meta-regression -- Limitations of meta-regression -- Conclusion -- 22. Preparing a statistical analysis plan -- Summary -- Introduction -- Data management -- Statistical procedures -- Data safety and monitoring board -- Sample size -- Interim analysis -- Reports to investigators -- Sensitivity analysis -- Tables of presentation and publication -- Software -- Reporting guidelines -- General policies -- Privacy considerations -- Apendices -- What is in the literature about SAP? -- Conclusion --; 24. Survival analysis -- Summary -- Introduction -- Documenting time-to-event (survival) data -- the rationale for time-to-event (survival) analysis -- Methods for survival analysis -- Comparing groups -- Practical considerations in the desin of time-to-event studies -- Conclusion -- 25. Interim analyses in randomized trials -- Summary -- Introduction -- Interim analysis defined -- Design of an interim analysis -- Data monitoring committees -- Consequences of stopping early for benefit -- Conclusion -- 26. Conflicts of interest reporting -- Summary -- Introduction -- Legal implications -- Types of conflict of interest -- Who should disclose conflicts of interest? -- When must conflicts of interest be disclosed? -- Guidelines and recommendations for disclosure -- Why must personal financial interests be disclosed? -- Alternatives to disclosure policies -- Conclusion -- 27. Authorship-modern approaches and reporting -- Summary -- Introduction -- Academic stream -- Educational stream -- Industrial stream -- Popular media stream -- Conclusion -- 28. Randomized trials reporting checklists -- Summary -- Introduction -- Consort statement -- Nonpharmacological trials -- NPT extension to consort statement -- CLEAR NPT -- Conclusion -- 29. Observational studies reporting checklists -- Summary -- Introduction -- Checklist for observational studies: the STROBE statement -- Guide to investigators: how to used the STROBE statement -- The STROBE statement: explanations of checklist items -- Conclusion -- 30. Meta-analysis reporting checklists -- Summary -- Introduction -- Meta-analysis reporting checklists -- Conclusion -- Resources and contacts for surgical research -- Summary -- Introduction -- Mentorship -- Graduate programes -- Online courses -- Textbooks and journals -- Courses and workshops -- Contract research organizations -- Conclusion -- Glossary of terms.
  • Digital
    Ruth Tappen, EDD, RN, FAAN, Professor, Christine E. Lynn Eminent Scholar in Nursing, Christine E. Lynn College of Nursing, Florida Atlantic University, Boca Raton, Florida.
    R2Library2016
    "Teaches students how to prepare research proposals and carry out research studies using a practical approach. The second edition puts a greater emphasis on evidence-based practice, quality improvement, and the use of aggregate data. The outstanding feature of this text is its reality-based approach to the actual conduct of research. The text also reflects current practice and current thinking about research and integrates qualitative and quantitative methods, including emerging mixed methods"-- Provided by publisher.
  • Digital
    Mieczyslaw Pokorski, editor.
    Springer2019
    This book gathers multidisciplinary articles that present advances of our understanding of diseases and the effective treatment of patients. The authors share recent clinical and experimental research findings, highlighting poorly understood areas with uncertain treatment outcomes, such as giant-cell bone tumors and their propensity to metastasize to the lungs; subterranean rehabilitation in pulmonary disorders; male reproductive hormone regulation during physical exercise in hyperbaric, hyperoxic environments, like underwater diving; and amelioration of cognitive decline owing to increased cerebral blood transit time after internal carotid artery stenting. Other topics include new concepts and innovations in the treatment of diabetes in pregnancy, and leg ulcers in chronic venous insufficiency, as well as molecular research on the toxic effects of oxidative stress, impaired cell autophagy, and experimental conditions resembling air pollution. Featuring the latest interdisciplinary advances in biomedicine, this book is a valuable resource for medical professionals, both academics and practitioners, and all allied health-care workers.
  • Digital
    Vijay C. Verma, Alan C. Gange, editors.
    Springer2014
    In recent years there has been significant attention paid on the endophytic research by various groups working within this domain. Mutualistic endophytic microbes with an emphasis on the relatively understudied fungal endophytes are the focus of this special book. Plants are associated with micro-organisms: endophytic bacteria and fungi, which live inter- and intra-cellularly without inducing pathogenic symptoms, but have active biochemical and genetic interactions with their host. Endophytes play vital roles as plant growth promoters, biocontrol agents, biosurfactant producers, enzymes and secondary metabolite producers, as well as providing a new hidden repertoire of bioactive natural products with uses in pharmaceutical, agrochemical and other biotechnological applications. The increasing interest in endophytic research generates significant progress in our understanding of the host-endophyte relationship at molecular and genetic level. The bio-prospection of microbial endophytes has led to exciting possibilities for their biotechnological application as biocontrol agent, bioactive metabolites, and other useful traits. Apart from these virtues, the microbial endophytes may be adapted to the complex metabolism of many desired molecules that can be of significant industrial applications. These microbes can be a useful alternative for sustainable solutions for ecological control of pests and diseases, and can reduce the burden of excess of chemical fertilizers for this purpose. This book is an attempt to review the recent development in the understanding of microbial endophytes and their potential biotechnological applications. This is a collection of literature authored by noted researchers having signatory status in endophytic research and summarizes the development achieved so far, and future prospects for further research in this fascinating area of research.
  • Digital
    Gyan Prakash, Takeshi Iwata, editors.
    Springer2017
    This book presents the state of the art in genetic eye research in Asia and the Pacific. Though there has been an explosion of information on genetic eye research in western countries, more than sixty percent of the human genes involved in eye diseases in the Asian and Pacific population remain unknown. However, new efforts and a new awareness have sparked important discussions on the subject, and new plans are being implemented to discover the genes responsible for many eye diseases in the population. The book reviews the latest findings; its content ranges from genetic aspects of human migration to DNA sequence analysis, genome-wide association analysis, and disease phenotypes. The efforts of the Asian Eye Genetic Consortium (AEGC) are also discussed. The book's editors have been instrumental in developing strategies for discovering the new Asian genes involved in many eye diseases. All chapters were written by leading researchers working on Asian eye genetics from the fields of Human Genetics, Ophthalmology, Molecular Biology, Biochemistry, Sensory Sciences, and Clinical Research. Advances in Vision Research, Volume I will prove to be a major resource for all researchers, clinicians, clinical researchers, and allied eye health professionals with an interest in eye diseases among the Asian population.
  • Print
    Cheryl Iverson (chair) [and others].
    Status: Not Checked Out
    Types of articles -- Manuscript preparation -- References -- Visual presentation of data -- Ethical and legal considerations -- Editorial assessment and processing -- Grammar -- Punctuation -- Plurals -- Capitalization -- Correct and preferred usage -- Non-English words, phrases, and accent marks -- Medical indexes -- Abbreviations -- Nomenclature -- Eponyms -- Greek letters -- Units of measure -- Numbers and percentages -- Study design and statistics -- Mathematical composition -- Typography -- Manuscript editing and proofreading -- Glossary of publishing terms -- Resources.
  • Digital
    Stacy L. Christiansen, Cheryl Iverson, Annette Flanagin, Edward H. Livingston, Lauren Fischer, Connie Manno, Brenda Gregoline, Tracy Frey, Phil B. Fontanarosa, Roxanne K. Young.
    "The AMA Manual of Style, 11th edition, is a must-have guide for those seeking to publish research findings and anyone involved in medical, health, or scientific writing and publishing. The manual offers guidance on nuts-and-bolts topics including punctuation, capitalization, and grammar. It also provides guidance on how to navigate the dilemmas that authors, researchers and their institutions, medical editors and publishers, writers, and members of the news media who cover scientific research confront on a daily basis. Written by an expert committee of JAMA Network editors, this 11th edition thoroughly covers ethical and legal issues, authorship, conflicts of interest, scientific misconduct, and intellectual property, in addition to preparation of articles for publication, style, terminology, measurement, and quantification"-- Provided by publisher.
  • Digital
    David R. Gross.
    Springer2009
    General principles of animal selection and normal physiological values -- Preanesthesia, anesthesia, chemical restraint, and the recognition and treatment of pain and distress -- Normal cardiac function parameters -- Measuring cardiac function -- Measuring vascular function and ventricular/arterial coupling dynamics -- Isolated heart preparations, problems, and pitfalls -- Cardiovascular effects of anesthetics, sedatives, postoperative analgesic agents, and other pharmaceuticals -- Naturally occurring and iatrogenic animal models of valvular, infectious, and arrhythmic cardiovascular disease -- Iatrogenic models of ischemic heart disease -- Iatrogenic, transgenic, and naturally occurring models of cardiomyopathy and heart failure -- Iatrogenic, congenic, and transgenic models of hypertension -- Naturally occurring, iatrogenic and transgenic models of atherosclerotic disease -- Animal models for the study of neurohumeral and central neural control of the cardiovascular system -- Other transgenic animal models used in cardiovascular studies
  • Print
    compiled by Anne-Laure Bourre.
    Status: Not Checked Out
  • Digital
    Helvi Kyngäs, Kristina Mikkonen, Maria Kääriäinen, editors.
    Springer2020
    This book provides principles on content analysis and its application into development of nursing theory. It offers clear guidance to students, lecturers and researchers to gain a deeper understanding of the method of content analysis, its implementation into their own research and criteria of trustworthiness evaluation. The book is written in user-friendly language with provided research examples and cases, and the content is illustrated by figures and tables. The authors offer their expertise in providing a well thought through explanation of content analysis in didactical style, which will enhance university education. The book includes highly experienced researchers who have published articles on content analysis and the trustworthiness of the method with more than 10 000 citations. Divided into two parts, this book explores the application of content analysis into nursing science. The first part presents the philosophical position of content analysis, inductive and deductive methods of using content analysis, trustworthiness of the method, and ethical consideration of using content analysis. The second part informs on the theory development based on content analysis, conceptualization of the concepts of content analysis into generation of items and instrument development, and statistical testing of a hypothetical model. The last chapter shows a new approach to using content analysis in systematic reviews and quality evaluation of methodology within systematic review process. The book is an essential tool for nursing science, providing instruction on key methodological elements in order to provide rigorously conducted empirical research for clinical practice and nursing education. .
  • Digital
    by Adam Gacek.
    eBook Comp Acad2012
    The main sequence is comprised of approximately 200 entries dealing with almost all aspects of Arabic manuscript studies (codicology and paleography); includes appendices covering abbreviations, letterforms, såurah-headings, major reference works, and a guide to the description of manuscripts, as well as charts of major historical periods and dynasties.
  • Digital
    edited by Margaret J. Foster, Sarah T. Jewell.
    ProQuest Ebook Central2017Limited to 1 simultaneous users
    This book guides librarians in defining and marketing their services, covering topics such as co-authorship, stakeholders, developing documentation and conducting the reference interview, systematic reviews standards, search strategy techniques, and best practices for reporting the findings.
  • Digital
    Eric Tatt Wei Ho.
    The fruit fly, Drosophila melanogaster, is a key model species for biological research. Trained humans can manipulate, inspect and dissect individual flies, but these operations are often rate-limiting bottlenecks for screening and experimentation. Here I present a high-speed, economical robot for handling non-anesthetized adult flies. Using machine vision the robot tracks a fly's thorax and gently grabs it ~400 ms after targeting. The robot can then translate and rotate the picked fly, inspect its phenotype, dissect or release it, and thereby rapidly prepare multiple flies sequentially for a wide range of experimental formats. In one illustration, the robot restrained flies and dissected the cuticle to permit two-photon imaging of neural dynamics. In another, the robot sorted flies by sex. The robot's tireless capacity for accurate, repeatable manipulations will enable experiments and biotechnology applications that would otherwise be totally infeasible, especially those requiring high-throughput capture, testing and assessment of individual fly attributes.
  • Digital
    editor, Susan E. White.
    AccessEmergency MedicineFulltext
    AccessEmergency MedicineReview Questions
    Introduction to medical research -- Study designs in medical research -- Summarizing data & presenting data in tables & graphs -- Probability & related topics for making inferences about data -- Research questions about one group -- Research questions about two separate or independent groups -- Research questions about means in three or more groups -- Research questions about relationships among variables -- Analyzing research questions about survival -- Statistical methods for multiple variables -- Survey research -- Methods of evidence-based medicine and decision analysis -- Reading the medical literature.
  • Digital
    edited by Morteza Jalali, Francesca Y.L. Saldanha, Mehdi Jalali ; foreword by Dame Sally Davies.
    ScienceDirect2017
  • Print
    Juliet Corbin, International Institute for Qualitative Methodology, Anselm Strauss.
    Status: Not Checked Out
    Inspiration and background -- Theoretical foundations -- Practical considerations for getting started -- Prelude to analysis -- Strategies for qualitative data analysis -- Memos and diagrams -- Theoretical sampling -- Context -- Process -- Techniques for achieving theoretical integration -- The use of computer programs in qualitative data analysis -- Open coding: identifying concepts -- Developing concepts in terms of their properties and dimensions -- Analyzing data for context -- Bringing process into the analysis -- Integrating categories -- Writing theses, monographs, and dissertations, and giving talks -- About your research -- Criteria for evaluation -- Student questions and answers.
  • Digital
    Juliet Corbin and Anselm Strauss.
    SAGE2008
    Introduction -- Practical considerations -- Prelude to analysis -- Strategies for qualitative data analysis -- Introduction to context, process and theoretical integration -- Memos and diagrams -- Theoretical sampling -- Analyzing data for concepts -- Elaborating the analysis -- Analyzing data for context -- Bringing process into the analysis -- Integrating categories -- Writing theses, monographs, and giving talks -- Criterion for evaluation -- Student questions and answers.
  • Digital
    Brianna Rego.
    In 1952, the largest manufacturer of cigarettes, Philip Morris, founded a Department of Research and Development (R& D) that would ultimately elevate the company to its dominating role in the tobacco landscape. As revealed through internal industry documents available online and released through litigation, this study highlights both the role of scientific research in a controversial industry, and the role of individual researchers in the unbridled growth of Big Tobacco during the second half of the twentieth century. Despite extensive research, industry results were rarely published and never without extensive scrutiny by industry executives and lawyers. This scientific silence is in stark contrast to the industry's public stance of denying the health hazards of smoking. The extent to which the tobacco men understood the hazards of their products--and the specific details of several research projects on the dangers of smoking--are discussed. The history of the Department of Research at Philip Morris demonstrates that just as public concern was growing that smoking might be dangerous, the tobacco industry was actively pursuing research proving the very thing they were trying to convince the public was a non-issue: that smoking is harmful.
  • Digital
    Imelda Coyne, Bernie Carter, editors.
    Springer2018
    This book provides a clear framework for conducting participatory research with children and young people supported with practical examples from international research studies. Our aim is to encourage more participatory research with children and young people on all matters that affect their lives. This book illustrates innovative ways of being participatory and sheds new light on involvement strategies that play to children's and young people's competencies. Participatory research is based on the recognition of children and young people as active contributors rather than objects of research. Participatory researchers support and value the voices of children and young people in all matters that concern them. Core to participatory research practice is a strengths-based approach that aims to promote the active engagement of children and young people in all stages of research, from inception to implementation. Engagement of children and young people requires the use of creative, participatory methods, tools and involvement strategies to reveal children's competencies. This book shares knowledge about creative participatory techniques that can enable and promote children's ways of expressing their views and experiences. The book provides guidance on appropriate techniques that reduce the power differential in the adult-child relationship and which optimise children's abilities to participate in research. This book is targeted at researchers, academics, practitioners who need guidance on what tools are available, how the tools can be used, advantages and challenges, and how best to involve children in all stages of a research project. It will provide several examples of how children can have an active participatory role in research. There is increasing interest in involving children as co-researchers but little guidance on how this can be done. This book fills a gap in the current books by addressing all of these issues outlined above and by providing worked examples from leading researchers and academics. It will have wide appeal across a range of different disciplines.
  • Digital
    Sharyl J. Nass, Laura A. Levit, and Lawrence O. Gostin, editors ; Committee on Health Research and the Privacy of Health Information, the HIPAA Privacy Rule, Board on Health Sciences Policy, Board on Health Care Services.
    eBook Comp Acad2009
    Introduction -- The value and importance of health information privacy -- The value, importance, and oversight of health research -- HIPAA, the privacy rule, and its application to health research -- Effect of the HIPAA privacy rule on health research -- A new framework for protecting privacy in health research.
  • Digital
    Marlene Oeffinger, Daniel Zenklusen, editors.
    Springer2019
  • Digital
    Michael F. Ochs, John T. Casagrande, Ramana V. Davuluri, editors.
    Springer2010
  • Digital
    edited by Vinod D. Kumar, Hannah Jane Tipney.
    Springer2014
    Introduction to biomedical literature text mining : context and objectives / Jeffrey D.Saffer and Vicki L. Burnett -- Accessing biomedical literature in the current information landscape / Ritu Khare, Robert Leaman, and Zhiyong Lu -- Mapping of biomedical text to concepts of lexicons, terminologies, and ontologies / Michael Bada -- Text mining for drug-drug interaction / Heng-Yi Wu, Chien-Wei Chiang, and Lang Li -- Biological information extraction and co-occurrence analysis / Georgios A. Pavlopoulos ... [et al.] -- Roles for text mining in protein function prediction / Karin M. Verspoor -- Functional molecular units for guiding biomarker panel design / Andreas Heinzel ... [et al.] -- Mining biological networks from full-text articles / Jan Czarnecki and Adrian J. Shepherd -- Scientific collaboration networks using biomedical text / Siddhartha R. Jonnalagadda ... [et al.] -- Predicting future discoveries from current scientific literature / Ingrid Petriéc and Bojan Cestnik -- Mining emerging biomedical literature for understanding disease associations in drug discovery / Deepak K. Rajpal ... [et al.] -- Integrative literature and data mining to rank disease candidate genes / Chao Wu, Cheng Zhu, and Anil G. Jegga -- Role of text mining in early identification of potential drug safety issues / Mei Liu, Yong Hu, and Buzhou Tang -- Systematic drug repurposing through text mining / Luis B. Tari and Jagruti H. Patel -- Mining the electronic health record for disease knowledge / Elizabeth S. Chen and Indra Neil Sarkar.
  • Digital
    Seward B. Rutkove.
    Springer2016
    Foreword -- PART 1: Basic considerations -- 1. So do you really want to pursue research? -- 2. What's in store: The brighter side of medical research -- 3. What's in store: The darker side of medical research -- 4. One degree of separation -- 5. Choosing and working with a mentor -- 6. Identifying a research niche you can call your own -- 7. Useful Definitions -- PART 2: Research Foundations and Structures -- 8. The Institutional Review Board: Do's, Don'ts, and Nevers... -- 9. Animal Care and Use Committees -- 10. Research beyond humans and vertebrates -- 11. Hiring Research Staff -- 12. Strategy and Tactics: Running a Successful Laboratory -- 13. Everything you ever wanted to know about collaboration Part 3: Successful Paper and Grant Writing -- 14. Writing a successful research paper. I -- Up to the point of submission -- 15. Writing a successful research paper. II -- Revising, resubmitting, and post-acceptance tasks -- 16. Funding: An overview -- 17. Where to apply for funding: making the right choices -- 18. Writing a winning grant application -- 19. Grant budgeting -- 20. Grant writing: Pearls and lumps of coal -- 21. Research Training, Fellowship, and Career grants -- 22. Grant review from the inside -- 23. Interpreting your reviews -- 24. To resubmit or not resubmit and how to do it -- Part 4: Good presentations, conferencing, networking, and other useful tools -- 25. The art of good presentation -- 26. Effective conferencing -- 27. Networking in the 21st century -- 28. Conflicts of interest -- 29. Scientific conduct and misconduct: what is right and proper, what is not, and what is somewhere in the middle -- 30. Article review and reading: being efficient and as thorough as you need to be -- 31. Patents -- 32. Working with industry -- Part 5: Career choices and life lessons -- 33. Jobs in biomedical science: seeking, landing, and changing -- 34. Academic Promotion and Titles -- 35. On being a mentor -- 36. Yardsticks of success -- 37. Research Life Lesson #1: Everything takes longer than you think, so plan for it -- 38. Research life lesson #2: A person's research is endlessly important to them -- 39. Research Life lesson #3: Balance, timing, cycles and seeing the big picture -- 40. Research Life Lesson #4: Your career is an ultramarathon, not a sprint -- 41. Conclusion: Nothing satisfies like meaningful work -- Acknowledgements.
  • Digital
    Daniela Cristina Stefan, editor.
    Springer2016
    1.Introduction: the need to conduct cancer research in developing countries -- 2.Steps of a research study: from research question to publication -- 3.Types of research designs -- 4.Clinical research in developing countries: An overview -- 5.The research protocol -- 6.Ethics of conducting cancer research in developing countries -- 7.Data management and statistics -- 8.Funding For Cancer Research and Clinical Studies in Low and Middle-Income Countries -- 9.International Collaboration in Cancer Research -- 10.Publication and dissemination of research findings.
  • Digital/Print
    Freireich, Emil J.; McGuire, William L.; Rosen, Steven T.
    Digital : Springerv. 5, 123-, 1982, 2005-
  • Digital
    edited by Daniel B. Fishman, Stanley B. Messer, David J.A. Edwards, Frank M. Dattilio.
    Oxford Clinical Psychology2017
    The terrain / Daniel B. Fishman and David J.A. Edwards -- Navigating the projects / Daniel B. Fishman -- "Cool kids/chilled adolescents" : cognitive behavioral therapy for youth with anxiety disorders in denmark / Mikael Thastum, Irene Lundkvist-Houndoumadi, Kristian Bech Arendt, Silke Stjerneklar and Daniel B. Fishman -- International implementation : universal principles meet local needs / Lauren J. Hoffman, Elaina A. Zendegui, and Brian C. Chu -- The efficacy of interpersonal psychotherapy : adolescent skills training (IPT-AST) in preventing depression / Sarah S. Kerner and Jami F. Young -- Identifying moderators of change from both RCTs and case studies / Laura Dietz -- Transference-focused psychotherapy for adult borderline personality disorder / Kenneth N. Levy, Kevin B. Meehan, Tracy L. Clouthier, Frank E. Yeomans, and John F. Clarkin -- Complementarity and clinical implications in using a mixed methods approach / William E. Piper and Carlos A. Sierra Hernandez -- Motivational enhancement therapy for increasing antidepressant medication adherence and decreasing clinical depression among adult latinos / Alejandro Interian, Ariana Prawda, Daniel B. Fishman, and William M. Buerger -- The best of both worlds / John C. Norcross -- An outside perspective / Harold Chui, Sarah Bloch-Elkouby, and Jacques P. Barber -- Themes and lessons learned / Daniel B. Fishman, Stanley B. Messer, David J.A. Edwards, and Frank Dattilio.
  • Digital
    Critical Assessment Skills Programme.
  • Digital
    Badenoch D.
  • Digital
    Karen Patrias ; Daniel L. Wendling, technical editor.
    NCBI Bookshelf2007
    Citing Published Print Documents -- 1. Journals -- 2. Books -- 3. Conference Publications -- 4. Scientific and Technical Reports -- 5. Dissertations and Theses -- 6. Bibliographies -- 7. Patents -- 8. Newspaper Articles -- 9. Maps -- 10. Legal Documents -- Citing Unpublished Material -- 11. Forthcoming ("in press") -- 12. Papers and Poster Sessions Presented at Meetings -- 13. Letters and Other Personal Communication -- 14. Manuscripts -- Citing Audio and Visual Media (audiocassettes, videocassettes, slides, photographs, etc.) -- 15. Books and Other Individual Titles in Audiovisual Formats -- 16. Journals in Audiovisual Formats -- 17. Prints and Photographs -- Citing Material on CD-ROM, DVD, or Disk -- 18. Books and Other Individual Titles on CD-ROM, DVD, or Disk -- 19. Journals on CD-ROM, DVD, or Disk -- 20. Databases on CD-ROM, DVD, or Disk -- 21. Computer Programs on CD-ROM, DVD, or Disk -- Citing Material on the Internet (Online) -- 22. Books and Other Individual Titles on the Internet -- 23. Journals on the Internet -- 24. Databases/Retrieval Systems on the Internet -- 25. Web Sites -- 26. Electronic Mail and Discussion Forums -- Appendixes -- Appendix A: Abbreviations for Commonly Used English Words in Journal Titles -- Appendix B: Additional Sources for Journal Title Abbreviations -- Appendix C: Abbreviations for Commonly Used English Words in Bibliographic Description -- Appendix D: ISO Country Codes for Selected Countries -- Appendix E: Two-Letter Abbreviations for Canadian Provinces and Territories and U.S. States and Territories -- Appendix F: Notes for Citing MEDLINE® /PubMed® -- Appendix: Content Updates.
  • Digital
    Martha L. Sylvia, Mary F. Terhaar.
    R2Library2018
    Introduction to clinical data management / Mary F. Terhaar -- Basic statistical concepts and power analysis / Martha L. Sylvia -- Value based purchasing / Mary F. Terhaar -- Using data to support the problem statement / Martha L. Sylvia -- Selecting quality measures / Martha L. Sylvia -- Preparing for data collection / Martha L. Sylvia and Mary F. Terhaar -- Secondary data collection / Emily Johnson and Martha L. Sylvia -- Primary data collection / Martha L. Sylvia -- Developing the analysis plan / Martha L. Sylvia and Mary F. Terhaar -- Data governance and stewardship / Martha L. Sylvia and Mary F. Terhaar -- Best practices for submission to the institutional review board / Mary F. Terhaar and Laura A. Taylor -- Creating the analysis data set / Martha L. Sylvia -- Exploratory data analysis / Martha L. Sylvia and Shannon Murphy -- Outcomes data analysis / Martha L. Sylvia and Shannon Murphy -- Summarizing the results of the project evaluation / Martha L. Sylvia -- Ongoing monitoring / Melissa Sherry and Martha Sylvia -- Data visualization / Erik Sederstrom -- Nursing excellence recognition and benchmarking programs / Heather Craven -- Risk adjustment / Martha L. Sylvia -- Big data, data science, and analytics / Marisa L. Wilson -- Predictive modeling / Martha L. Sylvia.
  • Digital
    edited by David Robertson, Gordon H. Williams.
    ClinicalKey2017
    Section I Fundamental Principles -- 1. Introduction to clinical research / Gordon H. Williams and David Robertson -- 2. Patient-oriented research / Ellen W. Seely and Steven Grinspoon -- 3. Clinical trials / Robert M. Califf -- 4. Introduction to epidemiology / Donna K. Arnett and Steven A. Claas -- 5. The patient-centered outcomes research institute / Joe V. Selby and Danielle M. Whicher -- 6. Health-care technology assessment (HTA) / Uwe E. Reinhardt -- 7. Health services research / J. Sanford Schwartz -- Section II Approaches -- 8. Measurement of biological materials / Mark D. Kellogg -- 9. Imaging tools in clinical research / Ruth M. Dunne, Alibhe C. O'Neill and Clare M. Tempany -- 10. Imaging tools in human research / Ruth M. Dunne, Alibhe C. O'Neill and Clare M. Tempany -- 11. Nanotechnology in clinical and translational research / James B. Baker Jr., Brent B. Ward and Thommey P. Thomas -- 12. The use of questionnaires and surveys / Marcia A. Testa and Donald C. Simonson -- 13. Informational technology / Shawn N. Murphy, Henry C. Chueh and Christopher D. Herrick -- 14. Principles of biostatistics / Kush Kapur -- 15. Good clinical practice and good laboratory practice / Nathalie K. Zgheib, Stephanie L. Tomasic and Robert A. Branch -- Section III Human Genetics -- Introduction to human genetics / Bruce R. Korf -- 17. Epidemiologic and population genetic studies / Angela J. Rogers and Scott T. Weiss -- 18. Pharmacogenetics of drug metabolism / Zerusenay Desta and David A. Flockhart -- 19. Statistical techniques for genetic analysis / Jessica Lasky-Su -- Section IV Human Pharmacology -- 20. Introduction to clinical pharmacology / Rommel G. Tirona and Richard B. Kim -- 21. Adverse drug events / Dan M. Roden -- Section V Societal Context of Human Research -- 22. Translating science to the bedside / Seema Basu -- 23. Regulatory environment / Christine Nguyen, Audrey Gassman and Hylton V. Joffe -- 24. Ethical issues in translational research and clinical investigation / Greg Koski -- 25. Clinical research in the public eye / Mary Wooley -- Section VI Research in Special Populations -- 26. Research in special populations / Todd W. Rice and Gordon R. Bernard -- 27. Research in the emergency care environment / James Quinn and Daniel J. Pallin -- 28. Psychiatric disorders / Alan F. Schatzberg -- 29. Research in special populations / Stephanie Studenski and Luigi Ferrucci -- 30. Clinical research in neurology / Keren Regev and Howard L. Weiner -- 31. Research in pediatrics / Lisa Bomgaars, Stacey Berg and Ann R. Stark -- 32. Cancer as a paradigm for translational and clinical biomedical research / César Serrano and George D. Demetri -- 33. Maintaining an emphasis on rare diseases with research initiatives and resources at the national center for advancing translational sciences / Stephen C. Groft and Rashmi Gopal-Srivastava -- Section VII Infrastructure -- 34. Clinical and Translational Science Infrastructure / David Robertson and Gordon H. Williams -- Section VIII Education, Training and Career Choices -- 35. Education, Training and Career Choices / Katherine E. Hartmann, Elizabeth Heitman and Nancy J. Brown -- A stepwise approach to a career in translational research / William F. Crowley Jr. -- Physician careers in the pharmaceutical industry / Ronald L. Krall -- Section IX Research in Academia -- 38. Industry-sponsored clinical research in academia / Italo Biaggioni -- 39. Governmental support of research / Sten H. Vermund and Salim Abdool Karim -- 40. The role of nonprofit, non-governmental funding in support of biomedical research / Rose Marie Robertson and Suzie Upton -- 41. Modern drug discovery and development / Daniel E. Salazar and Glenn Gormley -- 42. Pharmaceutical and biotechnology sector support of research / Joann Data -- Section X Prospectus -- 43. The future of clinical research / Gordon H. Williams and David Robertson.
  • Digital
    Mieczyslaw Pokorski, editor.
    Springer2018
    This book presents an update on new trends and developments in broadly defined medical disciplines. The reader will learn about a whole range of multidisciplinary topics, regarded as being important for advancing the understanding of disease pathogenicity, diagnostic methods, and patient management. These topics include a holistic approach to physiotherapy, with proprioceptive neuromuscular facilitation at the core of it. Furthermore potential ways to protect kidneys during ischemic coronary interventions, and psychosocial aspects in cancer survivors are discussed. Other topics deal with growth hormone deficiency in short children and responses of molecular markers of bone metabolism to growth hormone replacement therapy. In addition the modern use of transcranial laser-induced photobiomodulation showing surprising benefits in autism disorder is presented. The expert contributions take on the challenges presented to medical professionals by ever growing medical knowledge and various individual and contextual issues that require a multidisciplinary approach in patient management. The authors present bench-to-bed clinical research to make useful additions to the knowledge on contemporary diagnostic procedures, therapy, and quality of life of patients. The book aims to provide stimulus for new research ideas and to give new perspectives on practical clinical issues.
  • Digital
    John G. Brock-Utne.
    Springer2015
    This book provides insights into how to be a productive clinical researcher via real-life case examples of successful clinical research -- and also clinical research gone awry. Through these examples of success and failure, the book develops a blueprint for building a career in clinical research. Future medical practice depends on the quality of the clinical trials to which drugs, devices, and treatment procedures are subjected today. However, clinical trials are not easy to do, and many physicians and health care providers who attempt clinical research struggle in this endeavor, primarily because of lack of instruction. Clinical Research aims to fill the gap between training and research through case studies of a long-time clinical researcher's rich and varied experiences.
  • Digital
    Mieczyslaw Pokorski, editor.
    Springer2017
    This book is a blend of medical research and clinical practice. Advancements in practice are inextricably bound to have research underpinnings. The articles highlight a range of practical topics. The respiratory tract is upfront as the first line of defense of the organism. Virological and bacteriological aspects of the infections that continue to be a scourge worldwide, influenza and tuberculosis, are dealt with. Sleep disordered breathing is another hot topic. Allergy and atopy, and the role of nutraceuticals in providing anticancer benefits due to the inhibitory effects on tumor growth and angiogenesis are referred to. Other chapters describe the use of mesenchymal stem cells for regeneration of the worn away cartilage tissue in the knee. The assessment and management of cognitive decline, sarcopenia and frailty of old age also figure prominently in the texts. The book is an attempt to demonstrate the viability of a bench-to-bedside design in point-of-care patient applications. Hopefully, it will be a source of information on interdisciplinary medical research advancements, addressing the needs of medical professionals, from scientists to clinicians and allied health professionals.
  • Digital
    edited by Mohit Bhandari, Anders Joensson.
    Thieme MedOne Neurosurgery2009
    Thieme MedOne Education2009
    Thieme MedOne Plastic Surgery2009
    Thieme MedOne Otolaryngology2009
    Why we need clinical research -- Historical perspectives of clinical research -- Evidence-based surgery defined -- Myths and misconceptions about evidence-based medicine -- Becoming an evidence-based surgeon -- Principles of clinical research -- Various research design classifications -- Hierarchy of research studies: from case series to meta-analyses -- Randomized and nonrandomized studies -- Understanding research study design -- Clinical case series -- Case-control study -- Prospective cohort study -- Randomized trial -- Meta-analysis -- Economic analysis -- Diagnostic study -- Reliability study -- Understanding outcomes measurement -- Classification of outcomes -- What makes an outcome measure useful -- Common generic outcome scales for surgeons -- Common disease-specific outcome scales for surgeons -- Understanding treatment effects -- Common ways to present treatment effects -- Confidence interval defined -- P value defined -- Errors in hypothesis testing -- Clinical versus statistical significance -- Practice of clinical research -- Planning a research study -- Requirements of a clinical research proposal -- Identification of a good research question -- How to conduct a comprehensive literature search -- Guide to planning a randomized trial -- Guide to planning a nonrandomized study -- Study sample size -- How to budget for a research study -- Research ethics, review boards, and consent forms -- Regulatory issues in the evaluation of a new device or drug -- Strategies in research funding -- Conducting a research study -- Roles of the research team -- Role of a central methods center -- Role of a data monitoring committee -- Need for separate adjudication of outcomes -- Data management -- Study case report forms -- Study manual of operations -- Review of basic statistical principles -- Statistical means and proportions -- Regression analysis -- Analysis of variance -- Correlation defined.
  • Digital
    Allison J. Terry.
    R2Library2018
    The importance of research in the doctor of nursing practice degree -- Developing the researchable problem -- Conducting a literature review -- Ethics in clinical research -- Selecting a methodology for your capstone project -- Designing a clinically based quantitative Capstone research project -- Designing a clinically based qualitative Capstone research project -- Designing a clinically based mixed method Capstone research project -- Sampling -- Data collection -- Issues related to survey data collection -- Data analysis -- Writing the research report for potential publication -- Reducing 30-day hospital readmission of the heart failure patient -- A community-academic collaboration to impact childhood obesity -- The impact of evidence-based design -- The lived experience of chronic pain in nurse educators.
  • Digital
    Umakanta Sahoo.
    ScienceDirect2012
    Clinical research in Asia: A brief overview -- Clinical research in Japan -- Clinical research in India -- Clinical research in China -- Clinical research in South Korea -- Clinical research in Taiwan -- Clinical research in Singapore -- Clinical research in Thailand -- Clinical research in Malaysia -- Clinical research in Hong Kong -- Clinical research in the Philippines, Indonesia and Vietnam -- Conclusions.
  • Digital
    Rachel L. Richesson, James E. Andrews, editors.
    Springer2012
    "This book provides foundational coverage of key areas, concepts, constructs, and approaches of medical informatics as it applies to clinical research activities, in both current settings and in light of emerging policies. The field of clinical research is fully characterized (in terms of study design and overarching business processes), and there is emphasis on information management aspects and informatics implications (including needed activities) within various clinical research environments. The purpose of the book is to provide an overview of clinical research (types), activities, and areas where informatics and IT could fit into various activities and business practices. This book introduces and applies informatics concepts only as they have particular relevance to clinical research settings"--Provided by publisher.
  • Digital
    Rachel L. Richesson, James E. Andrews, editors.
    Springer2019
    This extensively revised new edition comprehensively reviews the rise of clinical research informatics (CRI). It enables the reader to develop a thorough understanding of how CRI has developed and the evolving challenges facing the biomedical informatician in the modern clinical research environment. Emphasis is placed on the changing role of the consumer, and the need to merge clinical care delivery and research as part of a changing paradigm in global healthcare delivery. Clinical Research Informatics presents a detailed review of using informatics in the continually evolving clinical research environment. It represents a valuable textbook reference for all students and practising healthcare informaticians looking to learn and expand their understanding of this fast-moving and increasingly important discipline. .
  • Digital
    R. Jennifer Cavalieri, Mark E. Rupp.
    ProQuest Ebook Central2013
    Introduction to research -- Site administration -- Managing financial processes -- Managing regulatory activities and documents -- Managing clinical trial activities -- Managing data and research records -- Conclusions and final remarks.
  • Digital
    Ad van Dooren.
    World Scientific2018
    The past -- Medicinal products : the development process -- Clinical studies : design aspects -- The rules and the regs -- The ethical pillars of clinical research -- The players part I : ethics committee and data monitoring committee -- The players part II : the sponsor and the clinical research organisation -- The players part III : the investigator, the sub-investigator and the clinical research coordinator -- The players part IV : the pharmacy and the clinical laboratory -- The players part V : the subject or patient -- Safety assessment -- The visits -- The essential documents part I : before study start -- The essential documents part II : during trial conduct -- The essential documents part III : after completion or termination of the trial -- Data management -- A special case : medical devices -- Compliance -- The challenge of monitoring -- The future of clinical trial monitoring : some afterthoughts.
  • Digital
    R2Library2016Limited to 1 simultaneous user
    Clinical research nursing focuses on the care of research participants and the protocols of clinical research and trials. The clinical researcher nurse (CRN) balances the needs of the participant and the requirements of research across settings. The result: exceptional, ethical, and safe care that yields reliable, valid data and findings, high quality research outcomes, and, in time, better quality health care. -- Provided by publisher.
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    edited by Alex Dmitrienko, Erik Pulkstenis.
    TandFonline2017
  • Digital
    Holly H.C. Kimko, Carl C. Peck, editors.
    Springer2011
    This edition includes both updates and new uses and issues concerning CTS, along with case studies of how clinical trial simulations are being applied in various therapeutic and application areas. Importantly, the book expands on the utility of CTS for informing decisions during drug development and regulatory review. Each chapter author was selected on the basis of demonstrated expertise in state-of-the-art application of CTS. The target audience for this volume includes researchers and scientists who wish to consider use of simulations in the design, analysis, or regulatory review and guidance of clinical trials. This book does not embrace all aspects of trial design, nor is it intended as a complete recipe for using computers to design trials. Rather, it is an information source that enables the reader to gain understanding of essential background and knowledge for practical applications of simulation for clinical trial design and analysis. It is assumed that the reader has a working understanding of pharmacokinetics and pharmacodynamics, modeling, pharmacometric analyses, and/or the drug development and regulatory processes.
  • Digital
    Steven Piantadosi.
    ProQuest Ebook Central2017
    Preliminaries -- Clinical Trials as research -- Why Clinical Trials are ethical -- Context for Clinical Trials -- Context for clinicak tricals -- Measurement -- Random error and bias -- Statistical perspectives -- Experiment design in clinical trials -- The trial cohort -- Development paradigms -- Translational clinical trials -- Early development and dose-finding -- Middle Development -- Comparative trials -- Adaptive design features -- Sample size and power -- Treatment allocation -- Treatment effects monitoring -- Counting subjects and events -- Estimating clinical effects -- Prognostic factor analyses -- Factorial design -- Crossover Designs -- Meta-analyes -- Reporting and authorship -- Misconduct and fraud in clinical research -- Appendix A Data and programs -- Appendix B Abbreviations -- Appendix C Notation and Terminology -- Appendix D Nuremberg code -- References -- Index.
  • Digital
    Tom Brody.
    ClinicalKey2016
    1. Origins of drugs -- 2. Clinical trial design -- 3. Run-in period -- 4. Inclusion/exclusion criteria, stratification, and subgroups -- part I -- 5. Inclusion/exclusion criteria, stratification, and subgroups -- part II -- 6. Blinding, randomization, and allocation -- 7. Placebo arm as part of clinical trial design -- 8. Intent-to-treat analysis versus per protocol analysis -- 9. Biostatistics -- part I -- 10. Biostatistics -- part II -- 11. Introduction to endpoints -- 12. Oncology endpoint -- objective response -- 13. Oncology endpoints : overall survival and progression-free survival -- 14. Oncology endpoints : time to progression -- 15. Oncology endpoint : disease-free survival -- 16. Oncology endpoint : time to distant metastasis -- 17. Neoadjuvant therapy versus adjuvant therapy -- 18. Hematological cancers -- 19. Biomarkers -- 20. Endpoints for immune diseases -- 21. Endpoints for infections -- 22. Health-related quality of life tools -- oncology -- 23. Health-related quality-of-life tools -- immune disorders -- 24. Health-related quality-of-life tools -- infections -- 25. Drug safety -- 26. Mechanism of action of diseases and drugs -- part I -- 27. Mechanism of action -- part II (cancer) -- 28. Mechanism of action -- part III (immune disorders) -- 29. Mechanisms of action -- part IV (infections) -- 30. Consent forms -- 31. Package inserts -- 32. Warning letters -- 33. Regulatory approval -- 34. Patents.
  • Digital
    Tom Brody.
    ScienceDirect2012
    The origins of drugs -- Introduction to regulated clinical trials -- Run in period -- Inclusion/exclusion criteria, stratification, and subgroups : part I -- Inclusion and stratification criteria : part II -- Randomization, allocation, and blinding -- Placebo arm as part of clinical study design -- Intent to treat analysis vs. per protocol analysis -- Biostatistics -- Introduction to endpoints for clinical trials in pharmacology -- Endpoints in clinical trials on solid tumors : objective response -- Oncology endpoints : overall survival and progression free survival -- Oncology endpoints : time to progression -- Oncology endpoint : disease free survival -- Oncology endpoint : time to distant metastasis -- Neoadjuvant therapy versus adjuvant therapy -- Hematological cancers -- Biomarkers and personalized medicine -- Endpoints in immune diseases -- Endpoints in clinical trials on infections -- Health related quality of life -- Health related quality of life instruments for immune disorders -- Health related quality of life instruments and infections -- Drug safety -- Mechanism of action : part I -- Mechanism of action, part II : cancer -- Mechanism of action, part III : immune disorders -- Mechanisms of action, part IV : infections -- Consent forms -- Package inserts -- Regulatory approval -- Patents.
  • Digital
    Kamal M.F. Itaní, Domenic J. Reda, editors.
    Springer2017
    The aim of this text is to provide the framework for building a clinical trial as it pertains to operative and non operative invasive procedures, how to get it funded and how to conduct such a trial up to publication of results. The text provides all details of building a scientifically and ethically valid proposal, including how to build the infrastructure for a clinical trial and how to move it forward through various funding agencies. The text also presents various types of clinical trials, the use of implantable devices and FDA requirements, and adjuncts to clinical trials and interaction with industry. Clinical Trials Design in Invasive Operative and Non Operative Procedures will be of interest to all specialists of surgery, anesthesiologists, interventional radiologists, gastroenterologists, cardiologists, and pulmonologists.
  • Digital
    Curtis L. Meinert.
    Wiley2012
    A thoroughly updated new edition of the essential reference on the design, practice, and analysis of clinical trials. "Clinical trials dictionary : terminology and usage recommendations", Second Edition presents clear, precise, meticulously detailed entries on allaspects of modern-day clinical trials. Written and compiled by one of the world's leading clinical trialists, this comprehensive volume incorporates areas of medicine, statistics, epidemiology, computer science, and bioethics - providing a treasure trove of key terms and ideas.
  • Digital
    Curtis L. Meinert.
    Wiley2013
  • Digital
    Michael O'Kelly, Bohdana Ratitch.
    Wiley2014
    "This book provides practical guidance for statisticians, clinicians, and researchers involved in clinical trials in the biopharmaceutical industry, medical and public health organisations. Academics and students needing an introduction to handling missing data will also find this book invaluable. The authors describe how missing data can affect the outcome and credibility of a clinical trial, show by examples how a clinical team can work to prevent missing data, and present the reader with approaches to address missing data effectively. The book is illustrated throughout with realistic case studies and worked examples, and presents clear and concise guidelines to enable good planning for missing data. The authors show how to handle missing data in a way that is transparent and easy to understand for clinicians, regulators and patients. New developments are presented to improve the choice and implementation of primary and sensitivity analyses for missing data. Many SAS code examples are included - the reader is given a toolbox for implementing analyses under a variety of assumptions"--Provided by publisher.
  • Digital
    by Richard J. Hayes, Lawrence H. Moulton.
    TandFonline2017
    Introduction -- Variability between clusters -- Choosing whether to randomise by cluster -- Choice of clusters -- Matching and stratification -- Randomisation procedures -- Sample size -- Alternative study designs -- Basic principles of analysis -- Analysis based on cluster-level summaries -- Regression analysis based on individual-level data -- Analysis of trials with more complex designs -- Ethical considerations -- Data monitoring -- Reporting and interpretation.
  • Digital
    editors, Julian P.T. Higgins and Sally Green.
    Cochrane2011-
    "The Cochrane Handbook for Systematic Reviews of Interventions (the Handbook) provides guidance to authors for the preparation of Cochrane Intervention reviews (including Cochrane Overviews of reviews)." "The Handbook is updated regularly to reflect advances in systematic review methodology and in response to feedback from users. Please refer to the web site for the most recent version, for interim updates to the guidance and for details of previous versions of the Handbook."
  • Digital
    Virginia Braun, Victoria Clarke, Debra Gray.
    Cambridge2017
    Is there more to qualitative data collection than face-to-face interviews? Answering with a resounding 'yes', this book introduces the reader to a wide array of exciting and novel techniques for collecting qualitative data in the social and health sciences. Collecting Qualitative Data offers a practical and accessible guide to textual, media and virtual methods currently under-utilised within qualitative research. Contributors from a range of disciplines share their experiences of implementing a particular technique, provide step-by-step guidance to using that approach, and highlight both the potential and pitfalls. From gathering blog data to the story completion method to conducting focus groups online, the methods and data types featured in this book are ideally suited to student projects and other time- and resource-limited research. In presenting several innovative ways that data can be collected, new modes of scholarship and new research orientations are opened up to student researchers and established scholars alike.-- Provided by Publisher.
  • Digital/Print
    Glenn A. Walker, Jack Shostak.
    Print2010
    Introduction & basics -- Topics in hypothesis testing -- The data set TRIAL -- The one-sample t-test -- The two-sample t-test -- One-way ANOVA -- Two-way ANOVA -- Repeated measures analysis -- The crossover design -- Linear regression -- Analysis of covariance -- The Wilcoxon signed-rank test -- The Wilcoxon rank-sum test -- The Kruskal-Wallis test -- The binomial test -- The Chi-square test -- Fisher's exact test -- McNemar's test -- The Cochran-Mantel-Haenszel test -- Logistic regression -- The log-rank test -- The Cox proportional hazards model -- Exercises.
  • Print
    Maureen M. Dawson, Brian A. Dawson, Joyce A. Overfield.
    Status: Not Checked Out
    Communication skills in science -- Using scientific literature -- Essay writing -- Writing practical reports -- The project report -- Scientific posters -- Oral presentations -- Preparing a curriculum vitae and job application.
  • Digital
    Kurt Lindemann.
    Wiley2017
    "Writing is an aspect often overlooked in the quest to provide students with the necessary skills to embark on a career in the increasingly important field of communication. For many students, putting one's thoughts and understanding of a topic onto paper can be a daunting task. Composing Research, Communicating Results: Writing the Communication Research Paper provides communication students with the knowledge and necessary tools to compose a variety of course-required papers that are scholarly, accessible, and well-written. Chapter coverage includes common myths associated with writing a research paper, brainstorming and researching topics, making and supporting arguments, style and formatting issues, writing the literature review, application and personal reaction papers, empirical research papers, presenting and publishing your work, and more. Each stage of the process is broken down into easy-to-follow steps supported by writing exercises and numerous examples drawn from published and student-written papers in the field. Composing Research, Communicating Results: Writing the Communication Research Paper fulfils an important and underserved niche in the classroom curricula, and is an essential resource for all students in communications-related courses"-- Provided by publisher.
  • Digital
    Milind Antani and Gowree Gokhale.
    ScienceDirect2012
  • Digital
    Brandé Flamez, Lamar University, A. Stephen Lenz, Texas A & M University Corpus Christi, Richard S. Balkin, University of Louisville, Robert L. Smith, Texas A & M University Corpus Christ.
    Wiley2017
    "This engaging book not only offers step-by-step guidance on planning, writing, and defending a dissertation but also helps create a beginning-to-end process that is meaningful, rewarding, and exciting. Each chapter answers commonly asked questions, contains a checklist for each part of the dissertation, provides a summary of key points, and lists additional resources. Topics addressed include tips for staying motivated, time management, and self-care; selecting a dissertation committee and narrowing down the topic; writing a proposal; preparing the literature review; creating the problem statement, purpose statement, and research questions; understanding research methodology and ethics; collecting and analyzing data; presenting results; and best of all-publishing a dissertation"--The publisher.
  • Digital
    Mark Elwood, Professor of Cancer Epidemiology, University of Auckland, New Zealand.
    Oxford Medicine Online2017
    Critical appraisal is now accepted as central to the development of rational health care and evidence-based medicine, by applying it to questions of aetiology, clinical therapy, and health care management. The reader will learn how to assess the strengths and weaknesses of new studies, and how to conduct their own studies.
  • Digital
    Committee to Review the Clinical and Translational Science Awards Program at the National Center for Advancing Translational Sciences, Board on Health Sciences Policy, Institute of Medicine of The National Academies ; Alan I. Leshner, Sharon F. Terry, Andrea M. Schultz, and Catharyn T. Liverman, editors.
    NAP2013
    This report provides the IOM committee's findings and recommendations regarding the progress and potential of NIH's CTSA Program. The report covers the breadth of the statement of task and highlights opportunities to bolster the program and ensure its continued success and sustainability in supporting clinical and translational researchers and serving the needs of the communities CTSAs are linked to and in which they reside. Chapter 2 discusses the ecosystem in which NCATS and the CTSA Program operate and provides the committee's vision for the next phase of the CTSA Program. Chapter 3 emphasizes the need for strong and active leadership by NCATS in establishing a clear vision and mission for the program along with measurable goals; supporting individual CTSAs; partnering and collaborating within the NIH and with external partners; and evaluating and communicating the program's value. Chapter 4 highlights specific opportunities and priorities in the areas of training and education, community engagement, and research related to child health. On the basis of discussions, conclusions, and recommendations outlined in the preceding chapters, in Chapter 5 the report concludes with next steps and potential future directions.
  • Digital
    Sara J. Czaja, Joseph Sharit, Jacquelyn B. James, editors.
    Springer2020
    This timely volume provides an up-to-date and comprehensive summary about what is known about aging and work and addresses the challenges and opportunities confronting older workers and organizations. The authors describe current and emerging topics related to work and aging adults such as working in teams, the increasing diversity of the labor force, work and caregiving, the implications of technology for an aging workforce, and health and wellness issues. The authorship is international; the authors are renowned for their respective work in the topical areas and represent a broad range of disciplines within academia, as well as offer perspectives from government and policy. Jobs, organizations, the labor market, and the workforce are experiencing dramatic change. Workers of all ages, including older workers, need to interact with the wide variety of ubiquitous technologies that are reshaping work processes, job content, work settings, communication strategies, and the delivery of training, and this book aims to update readers on the particular issues facing today's aging adults in the workplace. The chapters' broad and inclusive scope encompasses: Workplace aging and jobs in the 21st century The retirement income security outlook for older workers Population aging, age discrimination, and age discrimination protections Older workers and the contemporary labor market The role of aging, age diversity, and age heterogeneity within teams The intersection of family caregiving and work Current and Emerging Trends in Aging and Work is relevant to a broad audience of academic researchers, practitioners, and students in psychology, sociology, management, engineering (industrial and human factors), the health sciences, gerontology/geriatrics, and public health. It is also a useful resource for government and policy leaders, as well as workers and managers in the public and private sectors.
  • Digital
    Neil R. Smalheiser.
    ScienceDirect2017
    Reproducibility and robustness -- Choosing a research problem -- Basics of data and data distribution -- Experimental design: measures, validity, sampling, bias, randomization, power -- Experimental design: design strategies and controls -- Power estimation -- The data cleansing and analysis pipeline -- Topics to consider when analyzing data -- Null hypothesis statistical testing and the t-Test -- The "new statistics" and Bayesian inference -- ANOVA -- Non parametric tests -- Correlation and other concepts you should know -- How to record and report your experiments -- Data sharing and reuse -- The revolution in scientific publishing.
  • Print
    by Nancy Duarte.
    Status: Not Checked Out
    What if you sliced data and found a huge problem or opportunity? Data did its job, but now it needs a storyteller. The way insights are communicated could reverse or increase the trajectory of data. The actions you ask others to take today can change your future data. But getting others to move forward with those actions only happens when someone communicates well. Learn effective ways to turn your data into narratives that blend the power of language, numbers, and graphics. This book is not about visualizing data, there are plenty of books covering that. Instead, you'll learn how to transform numbers into narratives to drive action, and help communicate data in a way that creates outcomes both inside and outside your own organization.
  • Digital
    Shein-Chung Chow, Jen-Pei Liu.
    Wiley2014
    pt. I. Introduction -- Basic statistical concepts -- Basic design considerations -- Randomization and blinding -- pt. II. Designs and their classifications -- Designs for clinical trials -- Designs for cancer clinical trials -- Classification of clinical trials -- pt. III. Analysis of clinical data -- Analysis of continuous data -- Analysis of categorical data -- Censored data and interim analysis -- Sample size determination -- pt. IV. Issues in evaluation -- Issues in efficacy evaluation -- Safety assessment -- pt. V. Recent development -- Biomarkers and targeted clinical trials -- Trials for evaluating accuracy of diagnostic devices -- Statistical methods in translational medicine -- Adaptive clinical trial designs -- Traditional Chinese medicine -- pt. VI. Conduct of clinical trials -- Preparation and implementation of a clinical protocol -- Data management of a clinical trial.
  • Digital
    Gerald van Belle, Kathleen F. Kerr.
    Wiley2012
    Design and Analysis of Experiments in the Health Sciences; Contents; Preface; 1 The Basics; 1.1 Four Basic Questions; 1.2 Variation; 1.3 Principles of Design and Analysis; 1.4 Experiments and Observational Studies; 1.5 Illustrative Applications of Principles; 1.6 Experiments in the Health Sciences; 1.7 Adaptive Allocation; 1.7.1 Equidistribution; 1.7.2 Adaptive Allocation Techniques; 1.8 Sample Size Calculations; 1.9 Statistical Models for the Data; 1.10 Analysis and Presentation; 1.10.1 Graph the Data in Several Ways; 1.10.2 Assess Assumptions of the Statistical Model.
  • Print
    John W. Creswell, Vicki L. Plano Clark.
    Status: Not Checked Out
    "Combining the latest thinking about mixed methods research designs with practical, step-by-step guidance, the Second Edition of Designing and Conducting Mixed Methods Research now covers six major mixed methods designs. Authors John W. Creswell and Vicki L. Plano Clark walk readers through the entire research process, from formulating questions to designing, collecting data, and interpreting results and include updated examples from published mixed methods studies drawn from the social, behavioral, health, and education disciplines."--pub. desc.
  • Digital
    David Harrington, editor.
    Springer2012
  • Digital
    Cheryl Tatano Beck, DNSc, CNM, FAAN.
    R2Library2016
    "This is the first resource to provide graduate nursing students, students in other health sciences, and novice researchers with the tools and perspective to develop their own programs of research. Grounded in the author's 30 years of experience as a highly esteemed nurse researcher, the book guides nurses step by step through all aspects of program development. It underscores the importance of doing research that is knowledge driven and not limited to a particular method, and describes the characteristics of a successful research program and how to achieve it. It stresses the need for both qualitative and quantitative research methods to develop a valuable program of research. With a major focus on planing for sequential studies and describing potential pathways of a research trajectory, the book addresses options and timing of quantitative, qualitative, and mixed-method research designs, along with time management strategies"-- Back cover.
  • Digital
    Cara East.
    Springer2018
    This unique book is designed to help a medical team become a clinical research team. It includes practical information and tips for the initial stages of clinical research: building a team, negotiating a contract, developing a budget, and writing and improving a patient consent. Chapters describing the nuts and bolts of how to actually perform the study follow, including patient recruiting and retention, screening, follow-ups and handling monitor visits. Finally, there is discussion of the yearly reviews and disclosures and not just surviving, but acing, the all-important Food and Drug Administration audit. Clinical research moves medicine forward and is a necessary part of bringing any new therapy, device, or procedure into routine medical care. However, it can be costly and convoluted, and the methodologies of clinical research are not widely standardized. Decreasing some of the chaos present in American clinical research is the primary goal of this book. The second goal is to improve the understanding and education of those who enter clinical research, whether in the frontline work of the clinical research site, in the middleman companies who have a high turnover rate, at a research hospital or institution, or at medical corporations that depend on good clinical research to bring their products to market. The third reason is to standardize American clinical research and to remove some of the vagaries and inconsistencies in the field. Practical and user-friendly, Developing a Successful Clinical Research Program fills a need for a clear guide to developing and improving a first-class research program in any clinical setting.
  • Digital
    J. Steven Reznick (University of North Carolina, Chapel Hill).
    Cambridge2017
    The broad goals of science -- Developmental science in context -- Defining constructs and variables -- Validating measurement -- Designing developmental research -- Selecting a sample -- Collecting behavioral data -- Interviews and surveys -- Analyzing data -- Interpreting research results -- Building better developmental science -- Becoming better developmental scientists.
  • Digital
    Simon Day.
    Wiley1999
  • Digital
    edited by Ross C. Brownson, Graham A. Colditz, Enola K. Proctor.
    OSO2018
    The promise and challenges of dissemination and implementation research / Graham A. Colditz and Karen M. Emmons -- Terminology for dissemination and implementation research / Borsika A. Rabin and Ross C. Brownson -- Historical roots of dissemination and implementation science / James W. Dearing, Kerk F. Kee, and Tai-Quan Peng -- Ethical issues in dissemination and implementation research / James M. Dubois and Beth Prusaczyk -- The conceptual basis for dissemination and implementation research: lessons from existing models and frameworks / Rachel G. Tabak, David A. Chambers, Mary Hook, and Ross C. Brownson -- The role of economic evaluation in dissemination and implementation research / Ramesh Raghavan -- Designing for dissemination in chronic disease prevention and management / Neville Owen, Ana Goode, Takemi Sugiyama, Mohammad Javad Koohsari, Genevieve Healy, Brianna Fjeldsoe, and Elizabeth Eakin -- The role of organizational processes in dissemination and implementation research -- Gregory A. Aarons, Joanna C. Moullin, and Mark G. Ehrhart -- Systems thinking and dissemination and implementation research / Barbara L. Riley, Cameron D. Willis, Bev Holmes, Diane T. Finegood, Allan Best, and Jessie-Lee D. McIsaac -- Systems science methods in dissemination and implementation research / Douglas A. Luke, Alexandra B. Morshed, Virginia R. McKay, and Todd B. Combs -- Participatory approaches for study design and analysis in dissemination and implementation research / Meredith Minkler, Alicia L. Salvatore, and Charlotte Chang -- Enhancing dissemination through marketing and distribution systems: a vision for public health / Joseph T. Steensma, Matthew W. Kreuter, Christopher M. Casey, and Jay M. Bernhardt -- Design and analysis in dissemination and implementation research / John Landsverk, C. Hendricks Brown, Justin D. Smith, Patricia Chamberlain, Geoffrey M. Curran, Lawrence Palinkas, Mitsunori Ogihara, Sara Czaja, Jeremy D. Goldhaber-Fiebert, Wouter Vermeer, Lisa Saldana, Jennifer A. Rolls Reutz, and Sarah McCue Horwitz -- Measurement issues in dissemination and implementation research / Cara C. Lewis, Enola K. Proctor, and Ross C. Brownson -- Implementation strategies / Joann E. Kirchner, Thomas J. Waltz, Byron J. Powell, Jeffrey L. Smith, and Enola K. Proctor -- Fidelity and its relationship to implementation effectiveness, adaptation, and dissemination / Jennifer D. Allen, Rachel C. Shelton, Karen M. Emmons, and Laura A. Linnan -- Adaptation in dissemination and implementation science / Ana A. Baumann, Leopoldo J. Cabassa, and Shannon Wiltsey Stirman -- Furthering dissemination and implementation research: the need for more attention to external validity / Lawrence W. Green and Mona Nasser -- Evaluation approaches for dissemination and implementation research / Bridget Gaglio and Russell E. Glasgow -- Mixed methods evaluation in dissemination and implementation science / Lawrence A. Palinkas and Brittany Rhoades Cooper -- Dissemination and implementation research in community and public health settings / Cynthia A. Vinson, Katherine A. Stamatakis, and Jon F. Kerner -- Dissemination and implementation in social service settings / J. Curtis McMillen and Danielle R. Adams -- Implementation science in health care / Alison B. Hamilton and Brian S. Mittman -- Health dissemination and implementation within schools / Rebekka M. Lee and Steven L. Gortmaker -- Dissemination and implementation research in worksites / Peggy A. Hannon and Jeffrey R. Harris -- Policy dissemination research / Jonathan Purtle, Elizabeth A. Dodson, and Ross C. Brownson -- Dissemination and implementation research among racial/ethnic minority and other vulnerable populations / Antronette (Toni) Yancey, Beth A. Glenn, Chandra L. Ford, and Lashawnta Bell-Lewis -- Dissemination and implementation research in a global context / Rebecca Lobb, Shoba Ramanadhan, and Laura Murray -- Future issues in dissemination and implementation research / Ross C. Brownson, Graham A. Colditz, and Enola K. Proctor.
  • Print
    edited by Errol C. Friedberg and Philip C. Hanawalt.
    Status: Not Checked Out
  • Digital
  • Digital
    edited by Pranee Liamputtong.
    Springer2008
  • Digital
    by Randy Olson.
    ProQuest Ebook Central2009Limited to 3 simultaneous users
    Is the American public really ready for science? And is the world of science ready for the American public? Scientists wear ragged clothes, forget to comb their hair, and speak in a language that even they don't understand. Or so people think. Most scientists don't care how they are perceived, but in our media-dominated age, style counts. Enter Randy Olson. Fifteen years ago, marine biologist Olson bid farewell to the science world and shipped off to Hollywood ready to change the world. With his films, he has tried to bridge the cultural divide that has too often left science on the outside looking in. Now, in his first book, Olson recounts the lessons from his own hilarious--and at times humiliating--evolution from science professor to Hollywood filmmaker, offering up serious insights and poignant stories.--From publisher description.
  • Digital
    editors, Berthold Koletzko, Sibylle Koletzko, Frank Rümmele.
    Karger2010
    Innovations in infant milk feeding : from the past to the future / Koletzko, B. -- Novel insights into human lactation as a driver of infant formula development / Lønnerdal, B. -- The clinical challenge of preventing and treating malnutrition / Cooper, P.A. -- Progress of enteral feeding practice over time : moving from energy supply to patient-and disease-adapted formulationse / Koletzko, S. -- Molecular mechanisms of pediatric nutrition / Rümmele, F. -- Epidemiological research drives a paradigm shift in complementary feeding : the celiac disease story and lessons learnt / Nordyke, K. ... [et al.] -- Technological progress as a driver of innovation in infant foods / Ferruzzi, M.G.; Neilson, A.P. -- Health economic perspectives of pediatric malnutrition : determinants of innovative progress / Spieldenner, J. -- Economic perspectives on pediatric obesity : impact on health care expenditures and cost-effectiveness of preventive interventions / John, J. -- Sustainable clinical research, health economic aspects, and marketing : drivers of product innovation / Haschke, F.; Klassen-Wigger, P. -- Evaluation of dietetic product innovations : the relative role of preclinical and clinical studies / Makrides, M.; Gibson, R.A. -- Regulatory environment and claims : limits and opportunities / Martin, A. -- The role of consumers / Raats, M.M. -- Bioethics and innovation in pediatric nutrition research / Solomons, N.W. -- The role of pediatricians as innovators in pediatric nutrition / Greer, F.R. -- Promoting innovation in pediatric nutrition / Bier, D.M.
  • Digital
    Paul Smeyers, Marc Depaepe, editors.
    Springer2009
  • Digital
    XinQi Dong, editor.
    Springer2017
  • Print
    sous la direction de Jean-Gaël Barbara & Pierre Corvol.
  • Digital
    Joyce J. Fitzpatrick, editor.
    R2Library2018
    "This award-winning nursing reference, meticulously researched by luminaries in the field, represents the state of the art in nursing science. Comprehensive and concise, entries provide the most relevant and current research perspectives and demonstrate the depth and breadth of nursing research today. This one-stop reference presents key terms and concepts and clarifies their application to practice.The fourth edition has been substantially updated to contain the latest research for nurse scientists, educators, and students in all clinical specialties. With new information from the National Institute of Nursing Research, this reference is an essential compendium of nursing research for nursing students at any level and researchers in all clinical specialities" -- Publisher's description.
  • Digital
    Ramón Ribes, Palma Iannarelli, Rafael F. Duarte.
    Springer2009
  • Digital
    Committee on Advancing Understanding of the Implications of Environmental-chemical Interactions with the Human Microbiome, Board on Environmental Studies and Toxicology, Board on Life Sciences, Division on Earth and Life Studies.
    NCBI Bookshelf2018
    "A great number of diverse microorganisms inhabit the human body and are collectively referred to as the human microbiome. Until recently, the role of the human microbiome in maintaining human health was not fully appreciated. Today, however, research is beginning to elucidate associations between perturbations in the human microbiome and human disease and the factors that might be responsible for the perturbations. Studies have indicated that the human microbiome could be affected by environmental chemicals or could modulate exposure to environmental chemicals. Environmental Chemicals, the Human Microbiome, and Health Risk presents a research strategy to improve our understanding of the interactions between environmental chemicals and the human microbiome and the implications of those interactions for human health risk. This report identifies barriers to such research and opportunities for collaboration, highlights key aspects of the human microbiome and its relation to health, describes potential interactions between environmental chemicals and the human microbiome, reviews the risk-assessment framework and reasons for incorporating chemical-microbiome interactions"--Publisher's description.
  • Digital
    O.S. Miettinen, I. Karp.
    Springer2012
    Epidemiology: Grappling with the Concept -- Epidemiological Knowledge: Examples -- Etiology as a Pragmatic Concern -- Etiology as the Object of Study -- Etiologic Studies' Essentials -- Etiologic Studies' Typology -- Etiologic Studies' Objects Design -- Etiologic Studies' Methods Design -- Etiologic Studies' Intervention Counterparts -- Causal Studies' Acausal Counterparts -- Studies on Screening for a Cancer -- Some Paradigmatic Studies -- From Studies to Knowledge -- Fact-finding in Epidemiological Practice.
  • Digital
    Kenneth F. Schulz, PhD, MBA (Distinguished Scientist, FHI 360, Durham, NC, USA, Clinical Professor, Department of Obstetrics and Gynecology, University of North Carolina School of Medicine, Chapel HIll, NC, USA), David A. Grimes, MD (Clinical Professor, Department of Obstetrics and Gynecology, University of North Carolina School of Medicine, Chapel Hll, NC, USA) ; foreword by Richard Horton, FRCP, FRCPCH, FMedSci (Editor-in-Chief, The Lancet).
    ClinicalKey2019
  • Digital
    editor, Phil Langton.
    Wiley2013
    This concise, easy-to-follow text gives an insight into core techniques and practices in biomedical research and how, when and why a technique should be used and presented in the literature. Readers are alerted to common failures and misinterpretations that may evade peer review and are equipped with the judgment necessary to be properly critical of the findings claimed by research articles. --from publisher description
  • Digital
    Stephen P. Glasser, editor.
    Springer2014
    In its extensively revised and updated Second Edition, this book provides a solid foundation for readers interested in clinical research. Discussion encompasses genetic, pharmacoepidemiologic and implementation research. All chapters have been updated with new information and many new tables have been added to elucidate key points. The book now offers discussion on how to handle missing data when analyzing results, and coverage of Adaptive Designs and Effectiveness Designs and new sections on Comparative Effectiveness Research and Pragmatic Trials. Chapter 6 includes new material on Phase 0 Trials, expanded coverage of Futility Trials, a discussion of Medical Device approval, Off Label Drug use and the role of the FDA in regulating advertising. Additional new information includes the role of pill color and shape in association with the placebo effect and an examination of issues surrounding minority recruitment. The final chapter offers a new section on manuscript preparation along with a discussion of various guidelines being adopted by journals: CONSORT, STROBE, PRISMA, MOOSE and others; and coverage of Conflicts of Interest, Authorship, Coercive Citation, and Disclosures in Industry-Related Associations. Building on the strengths of its predecessor in its comprehensive approach and authoritative advice, the new edition offers more of what has made this book a popular, trusted resource for students and working researchers alike.
  • Digital
    Stanford Law School2011
    In response to a request by President Barak Obama on November 24, 2010, the Presidential Commission for the Study of Bioethical Issues oversaw a thorough fact-finding investigation into the specifics of the U.S. Public Health Service-led studies in Guatemala involving the intentional exposure and infection of vulnerable populations. Following a nine-month intensive investigation, the Commission has concluded that the Guatemala experiments involved gross violations of ethics as judged against both the standards of today and the researchers' own understanding of applicable contemporaneous practices. It is the Commission's firm belief that many of the actions undertaken in Guatemala were especially egregious moral wrongs because many of the individuals involved held positions of public institutional responsibility. The best thing we can do as a country when faced with a dark chapter is to bring it to light. The Commission has worked hard to provide an unvarnished ethical analysis to both honor the victims and make sure events such as these never happen again.
  • Digital
    Jeasik Cho.
    OSO2018
    Getting into the field -- A typology of the evaluation of qualitative research : toward a holistic view -- Practical evaluation tools and uses -- Change, challenges, and mixed methods research -- Getting out of the field -- Subject index -- References.
  • Digital
    by Jeffrey W. Alstete, Iona College, USa, Nicholas J. Beutell, Iona College, USA, John P. Meyer, Iona College, USA.
    ProQuest Ebook Central2018
    Faculty members, scholars, and researchers often ask where they should publish their work; which outlets are most suitable to showcase their research? Which journals should they publish in to ensure their work is read and cited? How can the impact of their scholarly output be maximized? The answers to these and related questions affect not only individual scholars, but also academic and research institution stakeholders who are under constant pressure to create and implement organizational policies, evaluation measures and reward systems that encourage quality, high impact research from their members. The explosion of academic research in recent years, along with advances in information technology, has given rise to omnipresent and increasingly important scholarly metrics. These measures need to be assessed and used carefully, however, as their widespread availability often tempts users to jump to improper conclusions without considering several caveats. While various quantitative tools enable the ranking, evaluating, categorizing, and comparing of journals and articles, metrics such as author or article citation counts, journal impact factors, and related measures of institutional research output are somewhat inconsistent with traditional goals and objectives of higher education research and scholarly academic endeavors.
  • Digital
    Sarah Jo Brown.
    R2Library2018
    Evidence-Based Nursing: The Research-Practice Connection, Fourth Edition introduces students to research methods and evidence-based practice. The text helps students understand research methods, how to appraise and use research evidence in clinical decision-making, and how to fully understand and engage in evidence-based practice. By linking evidence-based practice to recent research in safety and quality programs, it provides timely information in both healthcare and nursing settings. -- Provided by publisher.
  • Digital
    Pedro J. Gutiérrez Diez, Irma H. Russo, Jose Russo.
    Springer2012
    Historical Introduction -- Descriptive Biostatistics -- Inferential Biostatistics (I): Estimating Values of Biomedical Magnitudes -- Inferential Biostatistics (II): Estimating Biomedical Behaviors -- Equations: Formulating Biomedical Laws and Biomedical Magnitudes -- Systems of Equations: The Explanation of Biomedical Phenomena (I). Basic Questions -- Systems of Equations: The Explanation of Biomedical Phenomena (II). Dynamic Interdependencies -- Optimal Control Theory: From Knowledge to Control (I). Basic Concepts -- Optimal Control Theory: From Knowledge to Control (II). Biomedical Applications -- Game Theory.
  • Print
    Jonathan Orsay.
    Status: Not Checked Out
  • Digital
    Hamish Simpson, Peter Augat.
    Thieme-Connect2014
  • Digital
    Rose Utley, Kristina Henry, Lucretia Smith.
    R2Library2018Limited to 1 simultaneous user
    Understanding theoretical concepts / Rose Utley -- Strategies for using frameworks / Rose Utley -- The relationship between theory, research, and practice / Lucretia Smith -- Frameworks for behavioral change / Kristina Henry -- Care and caring frameworks / Rose Utley -- Human development frameworks / Rose Utley -- Frameworks for teaching and learning / Rose Utley -- Moral and ethical perspectives / Rose Utley -- Health and illness frameworks / Lucretia Smith -- Interpersonal and family frameworks / Kristina Henry, Lucretia Smith -- Needs-based frameworks / Rhea Faye D. Felicilda-Reynaldo, Lucretia Smith -- Physiological frameworks / Lucretia Smith -- Psychological frameworks / Kristina Henry -- Role-related frameworks / Rose Utley -- Economic frameworks / Kristina Henry -- Community and population health frameworks / Lucretia Smith -- Organizational systems frameworks / Kristina Henry -- Leadership frameworks for organizational systems / Kristina Henry -- Frameworks for evaluation / Rose Utley -- Sociocultural framework / Kristina Henry -- Application of frameworks to the nurse educator role / Rose Utley -- Application of frameworks to the clinician role / Maria Kenneally, Rose Utley -- Application of frameworks to leadership roles in nursing / Kristina Henry -- Application of frameworks to the nurse researcher role / Lucretia Smith.

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