Books by Subject

Bacteriology

  • Digital/Print
    edited by Kelly T. Hughes, Stanley R. Maloy.
    Digital : ScienceDirect2007
    Print2007
    Strain collections and genetic nomenclature / S.R. Maloy ... [et al.] -- Use of antibiotic-resistant transposons for mutagenesis / S.R. Maloy -- In vivo mutagenesis using EZ-Tn5 / J.R. Kirby -- Identification of essential genes in bacteria / D.R. Hillyard ... [et al.] -- Isolation of transposon insertions / S.R. Maloy -- Localized mutagenesis / S.R. Maloy -- Generation of deletions and duplications using transposons as portable regions of homology with emphasis on Mud and Tn10 transposons / K.T. Hughes -- Target-directed proteolysis in vivo / M. Eser ... [et al.] -- Sets of transposon-generated sequence-tagged mutants for structure-function analysis and engineering / B. Traxler ... [et al.] -- Using genomic microarrays to study insertional/transposon mutant libraries / D.N. Baldwin ... [et al.] -- Screening transposon mutant libraries using full-genome oligonucleotide microarrays / K. M. Winterberg ... [et al.] -- Creating recombination-activated genes and sequence-defined mutant libraries using transposons / L. Gallagher ... [et al.] -- Use of operon and gene fusions to study gene regulation in Salmonella / K.T. Hughes ... [et al.] -- Genomic screening for regulatory genes using the T-POP transposon / C. Lee ... [et al.] -- Recombineering: In vivo genetic engineering in E. coli, S. enterica, and beyond / J.A. Sawitzke ... [et al.] -- [lambda]-red genetic engineering in Salmonella enterica serovar Typhimurium / J.E. Karlinsey -- Probing nucleoid structure in bacteria using phage lambda integrase-mediated chromosome rearrangements / N. Garcia-Russell ... [et al.] -- Dissecting nucleic acid-protein interactions using challenge phage / S.R. Maloy ... [et al.] -- Mud-P22 / J.A. Crain ... [et al.] -- Phage metagenomics / V. Casas ... [et al.].
  • Digital
    Vijay C. Verma, Alan C. Gange, editors.
    Springer2014
    In recent years there has been significant attention paid on the endophytic research by various groups working within this domain. Mutualistic endophytic microbes with an emphasis on the relatively understudied fungal endophytes are the focus of this special book. Plants are associated with micro-organisms: endophytic bacteria and fungi, which live inter- and intra-cellularly without inducing pathogenic symptoms, but have active biochemical and genetic interactions with their host. Endophytes play vital roles as plant growth promoters, biocontrol agents, biosurfactant producers, enzymes and secondary metabolite producers, as well as providing a new hidden repertoire of bioactive natural products with uses in pharmaceutical, agrochemical and other biotechnological applications. The increasing interest in endophytic research generates significant progress in our understanding of the host-endophyte relationship at molecular and genetic level. The bio-prospection of microbial endophytes has led to exciting possibilities for their biotechnological application as biocontrol agent, bioactive metabolites, and other useful traits. Apart from these virtues, the microbial endophytes may be adapted to the complex metabolism of many desired molecules that can be of significant industrial applications. These microbes can be a useful alternative for sustainable solutions for ecological control of pests and diseases, and can reduce the burden of excess of chemical fertilizers for this purpose. This book is an attempt to review the recent development in the understanding of microbial endophytes and their potential biotechnological applications. This is a collection of literature authored by noted researchers having signatory status in endophytic research and summarizes the development achieved so far, and future prospects for further research in this fascinating area of research.
  • Digital/Print
    Alzira Maria Paiva de Almeida, Nilma Cintra Leal, editors.
    Digital : Springer2012
    Print2012
  • Print
    edited by Stanton B. Gelvin.
  • Digital
    Alan Ebringer.
    Springer2013
    Ankylosing spondylitis and Klebsiella is a comprehensive and informative text on the cause of Ankylosing spondylitis. Ankylosing spondylitis (AS) is a condition which affects 20 million people worldwide and is likely caused or initiated by a bowel infection from Klebsiella bacteria. When a patient is infected by Klebsiella bacteria, his or her immune system will make antibodies against all the antigens or molecules found in the microbe. Because some of the bacterial antigens resemble self tissues, the anti-bacterial antibodies will attack not only the bacteria but also the self tissues such as the joints and the cells having the same HLA molecules, which is how the disease AS starts. This is the concept of molecular similarity or "molecular mimicry" which previously has been found to work in two other autoimmune diseases; rheumatic fever and rheumatoid arthritis. The first paper on this subject was published in 1976 and since then over 100 papers on rheumatological topics have been published, from Prof Ebringer's group, at the Division of Life Sciences, King's College in London, UK. The relevant information from these papers is extracted and presented in this book format making it accessible to health professionals, research institutions, pharmaceutical companies and universities and the general public.
  • Digital
    This brief provides an overview of antibiotic resistance, including a summary of its current impact, the factors that contribute to its spread, and the policy recommendations put in place by federal and global public health agencies. It also reviews the debate around the regulation of antibiotic use in agriculture and examines new developments in policy and research associated with multidrug-resistant bacterial diseases and their underlying causes.
  • Digital
    edited by Stephen H. Gillespie.
    Springer2018
  • Digital
    DatabaseLimited to 6 simultaneous users
    Includes information on antimicrobial therapy and alternative therapy when the drug of choice cannot be given. The resource delivers information via review articles, capsule summaries, mini-reviews, and a guided PubMed search to pick up post-publication research.
  • Digital/Print
    World Health Organization.
    Digital : WHO2014
    Print2014
    This report examines, for the first time, the current status of surveillance and information on antimicrobial resistance (AMR) at country level worldwide, with particularly attention to antibacterial resistance.
  • Digital
    editors, Chin-Yi Chen, Xianghe Yan, Charlene R. Jackson.
    ScienceDirect2015
    1. Introduction to antimicrobial-resistant foodborne pathogens / Patrick Butaye, Maria Angeles Argudín and John Threlfall -- 2. Antimicrobial resistance of Shiga toxin-producing Escherichia coli / Jinru Chen -- 3. Antibiotic resistance in pathogenic Salmonella / Steven C. Ricke and Juliany Rivera Calo -- 4. Antimicrobial resistance and Campylobacter jejuni and C. coli / Mirko Rossi, Satu Olkkola, Mati Roasto, Rauni Kivistö and Marja-Liisa-Hänninen -- 5. Antimicrobial resistance in Yersinia enterocolitica / Anna Fabrega, Clara Ballesté-Delpierre and Jordi Vila -- 6. Antimicrobial resistance in Vibrio species / Craig Baker-Austin -- 7. Antimicrobial resistance in Shigella species / Keith A. Lampel -- 8. Antimicrobial resistance in Listeria spp. / Nathan A. Jarvis, Philip G. Crandall, Corliss A. O'Bryan and Steven C. Ricke -- 9. Antibiotic resistance in Enterococci : a food safety perspective / Anuradha Ghosh and Ludek Zurek -- 10. Clostridium difficile: a food safety concern? / Jane W. Marsh and Lee H. Harrison -- 11. Methods for the detection of antimicrobial resistance and the characterization of Staphylococcus aureus isolates from food-producing animals and food of animal origin / Kristina Kadlec, Sarah Wendlandt, Andrea T. Fessler and Stefan Schwarz -- 12. Non-phenotypic tests to detect and characterize antibiotic resistance mechanisms in Enterobacteriaceae / Agnese Lupo, Krisztina M. Papp-Wallace, Robert A. Bonomo and Andrea Endimiani -- 13. Monitoring and surveillance : the national antimicrobial resistance monitoring system / Emily Crarey, Claudine Kabera and Heather Tate -- 14. Risk assessment of antimicrobial resistance / H. Gregg Claycamp -- 15. Food microbial safety and animal antibiotics / Louis Anthony (Tony) Cox -- 16. Antibiotic-resistant bacteria and resistance genes in the water-food nexus of the agricultural environment / Pei-Ying Hong -- 17. Development and application of novel antimicrobials in food and food processing / Yangjin Jung and Karl R. Matthews -- 18. Database resources dedicated to antimicrobial peptides / Guangshun Wang -- 19. Metabolic network analysis-based identification of antimicrobial drug target in pathogenic bacteria / Vinayak Kapatral -- 20. Application of metagenomic technologies for antimicrobial resistance and food safety research and beyond / Chin-Yi Chen, Xianghe Yan, Siyun Wang and Charlene R. Jackson.
  • Digital
    guest editors: Shanmuganathan Rajasekaran, Rishi M. Kanna, Giuseppe Barbagallo.
    Thieme MedOne Neurosurgery2018
    Epidemiology, microbiology, and pathology of spinal infections / Abdulrazzaq Alobaid and Abdulaziz Al-Mutair -- Risk stratification and prevention of postoperative spinal infections / Hideyuki Arima, Leah Y. Carreon, and Steven D. Glassman -- Imaging in spinal infections / Anupama Maheswaran and Alberto Zerbi -- Instrumentation and spinal infections / Hisam Muhamad Ariffin, Yoshiharu Kawaguchi and ChungChek Wong -- Pyogenic spondylodiskitis : pathogenesis and clinical features / Mauro Antonio Fernandes, Luiz Roberto Vialle, and Phelipe de Souza Menegaz -- Pyogenic spondylodiskitis : diagnosis and management / Joost P.H.J. Rutges, Diederik Hendrik Ruth Kempen, and F. Cumhur Oner -- Spinal epidural abscess / Frank Kandziora, Klaus John Schnake, and Christoph-H. Hoffmann -- Spinal tuberculosis : pathogenesis, clinical features, and investigations / Rishi M. Kanna, Ajoy Prasad Shetty, and S. Rajasekaran -- Drug therapy for spinal tuberculosis / Mathew Varghese -- Surgical management of spinal tuberculosis / Ajoy Prasad Shetty, Rishi M. Kanna, and S. Rajasekaran -- Pediatric spinal infections / S. Rajasekaran, Rishi M. Kanna, and Ajoy Prasad Shetty -- Infectious lesions in the craniovertebral junction (suboccipital region) / Alexsander Yu Mushkin and Alexander V. Gubin -- Minimally invasive surgery in spinal infections / Moritz Perrech and Roger Hartl -- Human immunodeficiency virus and spinal infections / Robert Dunn -- Postoperative spondylodiskitis / Mayan Lendner, Jeffrey Green, Kris E. Radcliff, Joseph S. Butler, Hamadi Murphy, and Alexander R. Vaccaro -- Postoperative peri-implant infections / Claudio Lamartina, Alex Vesnaver, and Carlotta Martini -- Spinal infections in geriatric patients / Yoshiharu Kawaguchi -- Spinal infections and pseudoarthrosis / Sigurd Berven.
  • Digital
    Alessandro C. Pasqualotto, editor.
    Springer2010
  • Digital/Print
    von K.B. Lehmann und Rudolf Neumann.
    Digital : Google Books1896-
  • Print
    edited by I.C. Gunsalus, Roger Y. Stanier.
    Status: Not Checked Out
    v. 1. Structure -- v. 2. Metabolism -- v. 3. Biosynthesis -- v. 4. The Physiology of growth -- v. 5. Heredity -- v. 6 Bacterial diversity -- v. 7 Mechanisms of adaptation -- v. 8 Archaebacteria -- v. 10. The Biology of pseudomonas.
  • Digital
    Abdul Arif Khan, editor.
    Springer2012
  • Digital
    editors, Pascale Cossart, Institut Pasteur, Paris, France, Craig R. Roy, Yale University School of Medicine, New Haven, Connecticut, Philippe Sansonetti, Institut Pasteur, Paris, France.
    Am Soc Microbiol2019
    "In launching this book, we wanted to cover many aspects and mechanisms of cellular microbiology, but more importantly, we intended to show that cellular microbiology as a field has reached maturity, extending beyond the strictly cellular level to infections of various organs and tissues. Many model organisms (Yersinia, Salmonella, Shigella, and Listeria, among others) are foodborne pathogens, and tremendous progress has been achieved in deciphering how, when, and where bacteria interact with the gut. However, intestinal cells and the intestine are not the only cells and organs discussed in this book. There are also chapters on infections of the urogenital tract, the endothelial barriers, the nervous system, and the lungs. Progress in the latter two concern important public health infections produced by Mycobacterium leprae and Mycobacterium tuberculosis. These two bacteria, which were at first much more difficult to manipulate than Escherichia coli, are now genetically tractable, and their study can now benefit from all the techniques and approaches established with less fastidious bacteria"-- Provided by publisher.
  • Digital/Print
    Dirk Linke, Adrian Goldman, editors.
    Digital : Springer2011
    Print2011
    Adhesins of Human Pathogens from the Genus Yersinia / Jack C. Leo and Mikael Skurnik -- Adhesive Mechanisms of Salmonella enterica / Carolin Wagner and Michael Hensel -- Adhesion Mechanisms of Borrelia burgdorferi / Styliani Antonara, Laura Ristow and Jenifer Coburn -- Adhesins of Bartonella spp. / Fiona O'Rourke, Thomas Schmidgen, Patrick O. Kaiser, Dirk Linke and Volkhard A.J. Kempf -- Adhesion Mechanisms of Plant-Pathogenic Xanthomonadaceae / Nadia Mhedbi-Hajri, Marie-Agnès Jacques and Ralf Koebnik -- Adhesion by Pathogenic Corynebacteria / Elizabeth A. Rogers, Asis Das and Hung Ton-That -- Adhesion Mechanisms of Staphylococci / Christine Heilmann -- Protein Folding in Bacterial Adhesion: Secretion and Folding of Classical Monomeric Autotransporters / Peter van Ulsen -- Structure and Biology of Trimeric Autotransporter Adhesins / Andrzej Łyskowski, Jack C. Leo and Adrian Goldman -- Crystallography and Electron Microscopy of Chaperone / Usher Pilus Systems / Sebastian Geibel and Gabriel Waksman -- Crystallography of Gram-Positive Bacterial Adhesins / Vengadesan Krishnan and Sthanam V. L. Narayana -- The Nonideal Coiled Coil of M Protein and Its Multifarious Functions in Pathogenesis / Partho Ghosh -- Bacterial Extracellular Polysaccharides / Kateryna Bazaka, Russell J. Crawford, Evgeny L. Nazarenko and Elena P. Ivanova -- Carbohydrate Mediated Bacterial Adhesion / Roland J. Pieters -- The Application of NMR Techniques to Bacterial Adhesins / Frank Shewmaker -- Electron Microscopy Techniques to Study Bacterial Adhesion / Iwan Grin, Heinz Schwarz and Dirk Linke -- EM Reconstruction of Adhesins: Future Prospects / Ferlenghi Ilaria and Fabiola Giusti -- Atomic Force Microscopy to Study Intermolecular Forces and Bonds Associated with Bacteria / Steven K. Lower -- Assessing Bacterial Adhesion on an Individual Adhesin and Single Pili Level Using Optical Tweezers / Ove Axner, Magnus Andersson, Oscar Björnham, Mickaël Castelain and Jeanna Klinth, et al. -- Short Time-Scale Bacterial Adhesion Dynamics / Jing Geng and Nelly Henry -- Deciphering Biofilm Structure and Reactivity by Multiscale Time-Resolved Fluorescence Analysis / Arnaud Bridier, Ekaterina Tischenko, Florence Dubois-Brissonnet, Jean-Marie Herry and Vincent Thomas, et al. -- Inhibition of Bacterial Adhesion on Medical Devices / Lígia R. Rodrigues.
  • Digital/Print
    Tony Romeo, editor.
    Digital : Springer2008
    Print2008
  • Digital
    edited by Anne H. Delcour.
    Springer2013
    Bird's eye view of the bacterial landscape / Natividad Ruiz -- Visualizing the bacterial cell surface : an overview / Harald Engelhardt -- Purification of the outer membrane usher protein and periplasmic chaperone-subunit complexes from the P and type 1 pilus systems / Nadine S. Henderson and David G. Thanassi -- Experimental manipulation of the microbial functional amyloid called curli / Yizhou Zhou [and others] -- Visualization of gram-positive bacterial pili / Chungyu Chang [and others] -- Single cell microfluidic studies of bacterial motility / Adrien Ducret, Olivier Theodoly, and Tam Mignot -- Chromatographic analysis of the Escherichia coli polysialic acid capsule / Susan M. Steenbergen and Eric R. Vimr -- Analysis of exopolysaccharides in Myxococcus xanthus using confocal laser scanning microscopy / Wei Hu, Renate Lux, and Wenyuan Shi -- Assessment of multidrug efflux assemblies by surface plasmon resonance / Elena B. Tikhonova and Helen I. Zgurskaya -- Fluorescence microscopy and proteomics to investigate subcellular localization, assembly, and function of the type II secretion system / Tanya L. Johnson [and others] -- Pore formation by T3SS translocators : liposome leakage assay / Eric Faudry, Caroline Perdu, and Ina Attree -- Isolation of bacterial type IV machine subassemblies / Mayukh K. Sarkar [and others] -- Production and crystallization of bacterial type V secretion proteins / Hye-Jeong Yeo -- Assembly of bacterial outer membrane proteins / Jan Grijpstra, Martine P. Bos, and Jan Tommassen -- Outer membrane of gram-negative bacteria : lipid A isolation and characterization / Jessica V. Hankins [and others] -- Quantitative and qualitative preparations of bacterial outer membrane vesicles / Halima Chutkan [and others] -- In vitro peptidoglycan synthesis assay with lipid II substrate / Jacob Biboy, Nhat Khai Bui, and Waldemar Vollmer -- Extraction of cell wall-bound teichoic acids and surface proteins from Listeria monocytogenes / Filipe Carvalho [and others] -- Subfractionation and analysis of the cell envelope (lipo) polysaccharides of Mycobacterium tuberculosis / Anna E. Grzegorzewicz and Mary Jackson -- Protein disulfide bond formation in the periplasm : determination / Katleen Denoncin [and others] -- Using reporter genes and the Escherichia coli ASKA overexpression library in screens for regulators of the gram negative envelope stress response / Julia L. Wong, Stefanie L. Vogt, and Tracy L. Raivio -- Isolation of bacteria envelope proteins / Shu Quan [and others] -- Patch clamp electrophysiology for the study of bacterial ion channels in giant spheroplasts of E. coli / Boris Martinac [and others] -- Electrophysiological characterization of bacterial pore-forming proteins in planar lipid bilayers / Owen S. Mapingire, Beau Wager, and Anne H. Delcour.
  • Digital
    Kazuyuki Shimizu.
    ScienceDirect2013
    1. Main metabolism -- 2. Brief overview of metabolic regulation of a bacterial cell -- 3. Metabolic regulation by global regulators in response to culture environment -- 4. Conventional flux balance analysis and its applications -- 5. 13C-metabolic flux analysis and its applications -- 6. Effect of a specific-gene knockout on metabolism.
  • Digital
    edited by Michael D. Manson, Department of Biology, Texas A & M University, College Station, TX, USA.
    Springer2018
  • Digital
    Jayna L. Ditty, Shannon R. Mackey, Carl H. Johnson, editors.
    Springer2009
  • Digital
    edited by Tohru Minamino, Keiichi Namba.
    Springer2017
  • Digital
    edited by Jacques van Helden and Ariane Toussaint, Denis Thieffry.
    Springer2012
    Bacterial molecular networks : bridging the gap between functional genomics and dynamical modelling / Jacques van Helden, Ariane Toussaint, and Denis Thieffry -- Bacterial interactomes : from interactions to networks / Emmanuelle Bouveret and Christine Brun -- From bacterial to microbial ecosystems (metagenomics) / Shannon J. Williamson and Shibu Yooseph -- Prokaryote genome fluidity : toward a system approach of the mobilome / Ariane Toussaint and Mick Chandler -- Reticulate classification of mosaic microbial genomes using NeAT website / Gipsi Lima-Mendez -- From metabolic reactions to networks and pathways / Masanori Arita -- Predicting metabolic pathways by sub-network extraction / Karoline Faust and Jacques van Helden -- Directed module detection in a large-scale expression compendium / Qiang Fu [and others] -- Using phylogenetic profiles to predict functional relationships / Matteo Pellegrini -- Extracting regulatory networks of Escherichia coli from RegulonDB / Heladia Salgado [and others] -- Browsing metabolic and regulatory networks with BioCyc / Mario Latendresse, Suzanne Paley, and Peter D. Karp -- Algorithms for systematic identification of small subgraphs / Joseph Geraci, Geoffrey Liu, and Igor Jurisica -- The degree distribution of ntworks : statistical model selection / William P. Kelly, Piers J. Ingram, and Michael P.H. Stumpf -- MAVisto : a tool for biological network motif analysis / Henning Schwöbbermeyer and Röbbe Wünschiers -- Using MCL to extract clusters from networks / Stijn van Dongen and Cei Abreu-Goodger -- Protein complex prediction with RNSC / Andrew D. King, Nataša Pržulj, and Igor Jurisica -- Network analysis and protein function prediction with the PRODISTIN web site / Anaïs Baudot, Ouissem Souiai, and Christine Brun -- Using NeAT Toolbox to compare networks to networks, clusters to clusters, and network to clusters / Sylvain Brohée -- Analyzing biological data using R : methods for graphs and networks / Nolwenn Le Meur and Robert Gentleman -- Detecting structural invariants in biological reaction networks / Jörn Behre [and others] -- Petri nets in Snoopy : a unifying framework for the graphical display, computational modelling, and simulation of bacterial regulatory networks / Wolfgang Marwan, Christian Rohr, and Monika Heiner -- Genetic Network Analyzer : a tool for the qualitative modeling and simulation of bacterial regulatory networks / Grégory Batt [and others] -- Logical modelling of gene regulatory networks with GINsim / Claudine Chaouiya, Aurélien Naldi, and Denis Thieffry -- Modelling the evolution of mutualistic symbioses / Maren L. Friesen and Emily I. Jones -- Modelling the onset of virulence in pthogenic bacteria / Wilfred D. Kepseu [and others] -- Spatial and stochastic cellular modeling with the Smoldyn Simulator / Steven S. Andrews.
  • Digital
    edited by Akihito Yamaguchi, Kunihiko Nishino.
    Springer2018
    High Resolution Crystallographic Analysis of AcrB Using Designed Ankyrin Repeat Proteins (DARPins) -- Crystallographic Analysis of Drug and Inhibitor-Binding Structure of RND-Type Multidrug Exporter AcrB in Physiologically-Relevant Asymmetric Crystals -- Crystallographic Analysis of MATE-Type Multidrug Exporter with Its Inhibitors -- Crystallographic Analysis of the CusBA Heavy-Metal Efflux Complex of Escherichia coli.- Purification of AcrAB-TolC Multidrug Efflux Pump for Cryo-EM Analysis -- NMR Spectroscopy Approach to Study the Structure, Orientation, and Mechanism of the Multidrug Exporter EmrE -- Generation of Conformation-Specific Antibody Fragments for Crystallization of the Multidrug Resistance Transporter MdfA -- Biochemical Reconstitution and Characterization of Multi-Component Drug Efflux Transporters -- Covalently Linked Trimers of RND (Resistance-Nodulation-Division) Efflux Transporters to Study Their Mechanism of Action: Escherichia coli AcrB Multidrug Exporter as an Example -- Determining Ligand Path through a Major Drug Transporter, AcrB, in Escherichia coli.- Molecular Modeling of Multi-Drug Properties of Resistance Nodulation Division (RND) Transporters -- A Transcriptomic Approach to Identify Novel Drug Efflux Pumps in Bacteria -- Regulation of the Expression of Bacterial Multidrug Exporters by Two-Component Signal Transduction Systems -- Study of the Expression of Bacterial Multidrug Efflux Pumps in Anaerobic Conditions -- Identification of a Staphylococcus aureusEfflux Pump Regulator Using a DNA-Protein Affinity Technique -- High Throughput Flow Cytometry Screening of Multidrug Efflux Systems -- Single-Molecule Analysis of Membrane Transporter Activity by Means of a Microsystem -- Large Scale Femtoliter Droplet Array for Single Cell Efflux Assay of Bacteria -- Reconstitution and Transport Analysis of Eukaryotic Transporters in the Post-Genomic Era.
  • Digital
    edited by Olivier Espéli.
    Springer2017
    This volume presents state-of-the-art protocols for key experiments that have revolutionized our understanding of the bacterial nucleoid. This book is divided into five parts: Part I introduces molecular genetic methods to study bacterial nucleoids; Part II highlights the study of bacterial nucleoid with whole genome analysis method; Part III discusses molecular biology methods to study nucleoid structuring factors; Part IV looks at imaging bacterial nucleoid; and Part V explores biophysics of the bacterial nucleoid. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Thorough and cutting-edge, The Bacterial Nucleoid: Methods and Protocols is a valuable resource that provides a wealth of new information about this chromosome.
  • Digital
    edited by Alessio Mengoni, Marco Galardini, Marco Fondi.
    Springer2015
    Pulsed field gel electrophoresis and genome size estimates/ Rosa Alduina and Annalisa Pisciotta -- Comparative analyses of extrachromosomal bacterial replicons, identification of chromids, and experimental evaluation of their indispensability / Lukasz Dziewit and Dariusz Bartosik -- Choice of next-generation sequencing pipelines / F. Del Chierico ... [et al.] -- Pyrosequencing protocol for bacterial genomes / Ermanno Rizzi -- Bacterial metabarcoding by 16S rRNA gene ion torrent amplicon sequencing / Elio Fantini ... [et al.] -- Illumina-solexa sequencing protocol for bacterial genomes / Zhenfei Hu, Lei Cheng, and Hai Wang -- High-throughput phenomics / Carlo Viti ... [et al.] -- Comparative analysis of gene expression : uncovering expression conservation and divergence between Salmonella enterica serovar typhimurium strains LT2 and 14028S / Paolo Sonego ... [et al.] -- Raw sequence data and quality control / Giovanni Bacci -- Methods for assembling reads and producing contigs / Valerio Orlandini, Marco Fondi, and Renato Fani -- Mapping contigs using CONTIGuator / Marco Galardini, Alessio Mengoni, and Marco Bazzicalupo -- Gene calling and bacterial genome annotation with BG7 / Raquel Tobes ... [et al.] -- Defining orthologs and pangenome size metrics / Emanuele Bosi, Renato Fani, and Marco Fondi -- Robust identification of orthologues and paralogues for microbial pan-genomics using GET HOMOLOGUES : a case study of pIncA/C plasmids / Pablo Vinuesa and Bruno Contreras-Moreira -- Genome-scale metabolic network reconstruction / Marco Fondi and Pietro Liò -- From pangenome to panphenome and back / Marco Galardini, Alessio Mengoni, and Stefano Mocali -- Genome-wide detection of selection and other evolutionary forces / Zhuofei Xu and Rui Zhou -- Integrated microbial genome resource of analysis / Alice Checcucci and Alessio Mengoni.
  • Print
    Brenda A. Wilson, Abigail A. Salyers, Dixie D. Whitt, Malcolm E. Winkler.
    The power of bacteria -- Skin and mucosa : the first lines of defense against bacterial infections -- The innate immune system : always on guard -- The second line of defense : antibodies and cytotoxic T cells -- The normal human microbiota -- Microbes and disease : establishing a connection -- Mechanisms of genetic modification and exchange : role in pathogen evolution -- Identification of virulence factors : measuring infectivity and virulence -- Identification of virulence factors : molecular approaches for bacterial factors -- Identification of virulence factors : molecular approaches for host factors -- Bacterial strategies for evading or surviving host defense systems -- Toxins and other toxic virulence factors -- Delivery of virulence factors -- Virulence regulation -- Antimicrobial compounds -- How bacteria become resistant to antibiotics -- Vaccination : an underappreciated component of the modern medical armamentarium -- The gram-positive opportunistic pathogens -- The gram-negative opportunistic pathogens and emerging pathogens -- Biosecurity : the changing roles of microbiologists in an age of bioterrorism and emerging diseases.
  • Digital
    edited by Frank R. DeLeo and Michael Otto.
    Springer2008
    Isolation and characterization of lipopolysaccharides / Michael A. Apicella -- Proteomic analysis of proteins secreted by Streptococcus pyogenes / Michelle A. Chaussee, Emily J. McDowell, and Michael S. Chaussee -- Proteomic analysis to investigate regulatory networks in Staphylococcus aureus / Susanne Engelmann and Michael Hecker -- Microarray comparative genomic hybridization for the analysis of bacterial population genetics and evolution / Caitriona M. Guinane and J. Ross Fitzgerald -- Detection and inhibition of bacterial cell-cell communication / Scott A. Rice ... [et al.] -- A system for site-specific genetic manipulation of the relapsing fever spirochete Borrelia hermsii / James M. Battisti, Sandra J. Raffel, and Tom G. Schwan -- Transposon mutagenesis of the lyme disease agent Borrelia burgdorferi / Philip E. Stewart and Patricia A. Rosa -- The biofilm exopolysaccharide polysaccharide intercellular adhesin--a molecular and biochemical approach / Cuong Vuong and Michael Otto -- Analysis of Staphylococcus aureus gene expression during PMN phagocytosis / Jovanka M. Voyich, Dan E. Sturdevant, and Frank R. DeLeo -- Examining the vector-host-pathogen interface with quantitative molecular tools / Jason E. Comer, Ellen A. Lorange, and B. Joseph Hinnebusch -- Intracellular localization of Brucella abortus and Francisella tularensis in primary murine macrophages / Jean Celli -- Rate and extent of Helicobacter pylori phagocytosis / Lee-Ann H. Allen -- Culture, isolation, and labeling of Anaplasma phagocytophilum for subsequent infection of human neutrophils / Dori L. Borjesson -- Ultrastructural analysis of bacteria-host cell interactions / David W. Dorward -- Infection of human monocyte-derived macrophages with Coxiella burnetii / Jeffrey G. Shannon and Robert A. Heinzen -- Infection of epithelial cells with Salmonella enterica / Olivia Steele-Mortimer -- Determining the cellular targets of reactive oxygen species in Borrelia burgdorferi / Julie A. Boylan and Frank C. Gherardini -- Bioluminescent imaging of bacterial biofilm infections in vivo / Jagath L. Kadurugamuwa and Kevin P. Francis -- The cotton rat as a model for Staphylococcus aureus nasal colonization in humans : cotton rat S. aureus nasal colonization model / John F. Kokai-Kun -- A non-human primate model of acute group A Streptococcus pharyngitis / Paul Sumby, Anne H. Tart, and James M. Musser -- Target-based antimicrobial drug discovery / Lefa E. Alksne and Paul M. Dunman -- Sequence analysis of the variable number tandem repeat in Staphylococcus aureus protein A gene : spa typing / Barun Mathema, Jose Mediavilla, and Barry N. Kreiswirth.
  • Digital
    edited by Pontus Nordenfelt, Department of Clinical Sciences, Lund University, Division of Infection Medicine, Lund, Sweden, Mattias Collin, Department of Clinical Sciences, Lund University, Division of Infection Medicine, Lund, Sweden.
    Springer2017
    Protein-based strategies to identify and isolate bacterial virulence factors / Rolf Lood and Inga-Maria Frick -- Analysis of bacterial surface interactions with mass spectrometry-based proteomics / Christofer Karlsson, Johan Teleman, and Johan Malmström -- Differential radial capillary action of ligand assay (DRaCALA) for high-throughput detection of protein-metabolite interactions in bacteria / Mona W. Orr and Vincent T. Lee -- Identifying bacterial immune evasion proteins using phage display / Cindy Fevre, Lisette Scheepmaker, and Pieter-Jan Haas -- Competition for iron between host and pathogen : a structural case study on Helicobacter pylori / Wei Xia -- Common challenges in studying the structure and function of bacterial proteins : case studies from Helicobacter pylori / Daniel A. Bonsor and Eric J. Sundberg -- Development of a single locus sequence typing (SLST) scheme for typing bacterial species directly from complex communities / Christian F.P. Scholz and Anders Jensen -- Reconstructing the ancestral relationships between bacterial pathogen genomes / Caitlin Collins and Xavier Didelot -- Making fluorescent Streptococci and Enterococci for live imaging / Sarah Shabayek and Barbara Spellerberg -- Computer vision-based image analysis of bacteria / Jonas Danielsen and Pontus Nordenfelt -- Assessing vacuolar escape of Listeria monocytogenes / Juan J. Quereda, Martin Sachse, Damien Balestrino, Théodore Grenier, Jennifer Fredlund, Anne Danckaert, Nathalie Aulner, Spencer Shorte, Jost Enninga, Pascale Cossart, and Javier Pizarro-Cerdá -- Immobilization techniques of bacteria for live super-resolution imaging using structured illumination microscopy / Amy L. Bottomley, Lynne Turnbull, Cynthia B. Whitchurch, and Elizabeth J. Harry -- Negative staining and transmission electron microscopy of bacterial surface structures / Matthias Mörgelin -- Detection of intracellular proteins by high-resolution immunofluorescence microscopy in Streptococcus pyogenes / Assaf Raz -- Antibody guided molecular imaging of infective endocarditis infection / Kenneth L. Pinkston, Peng Gao, Kavindra V. Singh, Ali Azhdarinia, Barbara E. Murray, Eva M. Sevick-Muraca, and Barrett R. Harvey -- Zebrafish as a model for human bacterial infections / Melody N. Neely -- Determining platelet activation and aggregation in response to bacteria / Oonagh Shannon -- Killing bacteria with cytotoxic effector proteins of human killer immune cells : granzymes, granulysin, and perforin / Diego López León, Isabelle Fellay, Pierre-Yves Mantel, and Michael Walch -- In Vitro and in vivo biofilm formation by pathogenic Streptococci / Yashuan Chao, Caroline Bergenfelz, and Anders P. Håkansson -- Murine Mycobacterium marinum infection as a model for tuberculosis / Julia Lienard and Fredric Carlsson -- Generating and purifying fab fragments from human and mouse IgG using the bacterial enzymes IdeS, SpeB and Kgp / Jonathan Sjögren, Linda Andersson, Malin Mejàre, and Fredrik Olsson -- Measuring antibody orientation at the bacterial surface / Oonagh Shannon and Pontus Nordenfelt -- Toward clinical use of the IgG specific enzymes IdeS and EndoS against antibody-mediated diseases / Mattias Collin and Lars Björck.
  • Digital/Print
    edited by Virginia L. Clark, Patrik M. Bavoil.
    Digital : ScienceDirect2002
    Print2002
  • Digital
    edited by Jan Michiels and Maarten Fauvart.
    Springer2016
    Historical perspective on bacterial persistence / Natalie Verstraeten ... [et al.] -- Persisters : methods for isolation and identifying contributing factors-a review / Sarah E. Rowe ... [et al.] -- General method for measuring persister levels in Escherichia coli cultures / Niilo Kaldalu ... [et al.] -- Optimized method for measuring persistence in Escherichia coli with improved reproducibility / F. Goormaghtigh and L. Van Melderen -- Microplate-based system as in vitro model of biofilm growth and quantification / Ilse Vandecandelaere, Heleen Van Acker, and Tom Coenye -- Protocol for determination of the persister subpopulation in Candida Albicans biofilms / Katrijn De Brucker ... [et al.] -- Quantitative measurements of type I and type II persisters using ScanLag / Irit Levin-Reisman and Nathalie Q. Balaban -- Analyzing persister physiology with fluorescence-activated cell sorting / Mehmet A. Orman ... [et al.] -- Single-cell detection and collection of persister bacteria in a directly accessible femtoliter droplet array / Ryota Iino ... [et al.] -- Whole-cell-based high-throughput screening method to identify molecules targeting Pseudomonas Aeruginosa persister cells / Veerle Liebens, Valerie Defraine, and Maarten Fauvart -- Functional analysis of the role of toxin-antitoxin (TA) loci in bacterial persistence / Aaron T. Butt and Richard W. Titball -- Experimental evolution of Escherichia coli persister levels using cyclic antibiotic treatments / Bram Van den Bergh, Joran E. Michiels, and Jan Michiels -- In vitro models for the study of the intracellular activity of antibiotics / Julien M. Buyck ... [et al.] -- Murine model for Escherichia coli urinary tract infection / Thomas J. Hannan and David A. Hunstad -- Analysis of macrophage-induced Salmonella persisters / Robert A. Fisher, Angela M. Cheverton, and Sophie Helaine -- Population dynamics analysis of ciprofloxacin-persistent S. Typhimurium cells in a mouse model for Salmonella diarrhea / Patrick Kaiser, Roland R. Regoes, and Wolf-Dietrich Hardt -- Computational methods to model persistence / Alexandra Vandervelde ... [et al.].
  • Digital
    Walid El Sharoud, editor.
    Springer2008
  • Digital
    editors Laure Journet and Eric Cascales.
    Springer2017
    Identification of protein secretion systems in bacterial genomes using MacSyFinder / Sophie S. Abby and Eduardo P.C. Rocha -- Protein sorting prediction / Henrik Nielsen -- Cell fractionation / Melissa Petiti, Laetitia Houot, and Denis Duché -- Defining lipoprotein localisation by fluorescence microscopy / Maria Guillermina Casabona, Mylène Robert-Genthon, Didier Grunwald, and Ina Attrée -- Identification of lipoproteins using globomycin and radioactive palmitate / Nienke Buddelmeijer -- Defining membrane protein localization by isopycnic density gradients / Rhys A. Dunstan, Iain D. Hay, and Trevor Lithgow -- Cell surface exposure / Anna Konovalova -- Probing inner membrane protein topology by proteolysis / Maxence S. Vincent and Eric Cascales -- Mapping of membrane protein topology by substituted cysteine accessibility method (SCAM) / Mikhail Bogdanov -- Defining membrane protein topology using pho-lac reporter fusions / Gouzel Karimova and Daniel Ladant -- In vivo and in vitro protein-peptidoglycan interactions / Gang Li and S. Peter Howard -- Measure of peptidoglycan hydrolase activity / Yoann G. Santin and Eric Cascales -- Protein-protein interaction : Bacterial Two-Hybrid / Gouzel Karimova, Emilie Gauliard, Marilyne Davi, Scot P. Ouellette, and Daniel Ladant -- Protein-protein interactions : yeast two-hybrid system / Jer-Sheng Lin and Erh-Min Lai -- Protein-protein interactions : cytology two-hybrid / Krishnamohan Atmakuri -- Fusion reporter approaches to monitoring transmembrane helix interactions in bacterial membranes / Laureen Logger, Abdelrahim Zoued, and Eric Cascales -- Protein-protein interactions : co-immunoprecipitation / Jer-Sheng Lin and Erh-Min Lai -- Protein-protein interaction : tandem affinity purification in bacteria / Julie P.M. Viala and Emmanuelle Bouveret -- Site-directed and time-resolved photocrosslinking in cells metabolically labeled with radioisotopes / Raffaele Ieva -- Protein-protein interactions : pull-down assays / Arthur Louche, Suzana P. Salcedo, and Sarah Bigot -- Protein-protein interactions : surface plasmon resonance / Badreddine Douzi -- Assessing energy-dependent protein conformational changes in the TonB system / Ray A. Larsen -- Defining assembly pathways by fluorescence microscopy / Abdelrahim Zoued and Andreas Diepold -- Large complexes : cloning strategy, production, and purification / Eric Durand and Roland Lloubes -- Shearing and enrichment of extracellular type IV pili / Alba Katiria Gonzalez Rivera and Katrina T. Forest -- Blue native PAGE analysis of bacterial secretion complexes / Susann Zilkenat, Tobias Dietsche, Julia V. Monjarás Feria, Claudia E. Torres-Vargas, Mehari Tesfazgi Mebrhatu, and Samuel Wagner -- In situ imaging of bacterial secretion systems by electron cryotomography / Gregor L. Weiss, João M. Medeiros, and Martin Pilhofer -- Structural analysis of protein complexes by cryo electron microscopy / Tiago R.D. Costa, Athanasios Ignatiou, and Elena V. Orlova -- Bacterial filamentous appendages investigated by solid-state NMR spectroscopy / Birgit Habenstein and Antoine Loquet -- Energy requirements for protein secretion via the flagellar type III secretion system / Marc Erhardt -- Identification of effectors : precipitation of supernatant material / Nicolas Flaugnatti and Laure Journet -- Screening for secretion of the type VI secretion system protein Hcp by enzyme-linked immunosorbent assay and colony blot / Brent S. Weber, Pek Man Ly, and Mario F. Feldman -- Effector translocation : cya reporter assay / Suma Chakravarthy, Bethany Huot, and Brian H. Kvitko -- Monitoring effector translocation using the TEM-1 beta-lactamase reporter system / Julie Allombert, Anne Vianney, and Xavier Charpentier -- Effector translocation assay : differential solubilization / Irina S. Franco, Sara V. Pais, Nuno Charro, and Luís Jaime Mota -- Quantitative determination of anti-bacterial activity during bacterial co-culture / Juliana Alcoforado Diniz, Birte Hollmann, and Sarah J. Coulthurst.
  • Digital
    edited by Irina Artsimovitch, Thomas J. Santangelo.
    Springer2015
    Mapping the Escherichia coli transcription elongation complex with exonuclease III / Zhaokun Liu and Irina Artsimovitch -- Purification of bacterial RNA polymerase : tools and protocols / Vladimir Svetlov and Irina Artsimovitch -- Monitoring translocation of multisubunit RNA polymerase along the DNA with fluorescent base analogues / Anssi M. Malinen, Matti Turtola, and Georgiy A. Belogurov -- In vitro and in vivo methodologies for studying the sigma-54-dependent transcription / Martin Buck [and nine others] -- Methods for the assembly and analysis of in vitro transcription-coupled-to-translation systems / Daniel Castro-Roa and Nikolay Zenkin -- Site-specific incorporation of probes into RNA polymerase by unnatural-amino-acid mutagenesis and Straudinger-Bertozzi ligation / Anirban Chakraborty [and seven others] -- Reconstruction of factor-dependent, promotor proximal pausing in Drosophila nuclear extracts / Jian Li and David S. Gilmour -- Direct competition assay for transcription fidelity / Lucyna Lubkowska and Maria L. Kireeva -- Single-stranded DNA aptamers for functional probing of bacterial RNA polymerase / Danil Pupov and Andrey Kulbachinskiy -- Biochemical analysis of transcription termination by RNA polymerase III from yeast Saccharomyces cerevisiae / Aneeshkumar G. Arimbasseri and Richard J. Maraia -- Use of RNA polymerase molecular beacon assay to measure RNA polymerase interactions with model promotor fragments / Vladimir Mekler and Konstantin Severinov -- Preparation of cDNA libraries for high-throughput RNA sequencing analysis of RNA 5' ends / Irina O. Vvedenskaya, Seth R. Goldman, and Bryce E. Nickels -- In situ footprinting of E. coli transcription elongation complex with chloroacetaldehyde / A. Rachid Rahmouni and Christine Mosrin-Hauman -- Using solutes and kinetics to probe large conformational changes in the steps of transcription initiation / Emily F. Ruff, Wayne S. Kontur, and M. Thomas Record Jr. -- Manipulating archaeal systems to permit analyses of transcription elongation-termination decisions in vitro / Alexandra M. Gehring and Thomas J. Santangelo -- Purification of active RNA polymerase I from yeast / Francis Dean Appling and David Alan Schneider -- Transcription in archaea : preparation of Methanocaldococcus jannaschii transcription machinery / Katherine Smollet, Fabian Blombach, and Finn Werner -- Transcription in archaea ; in vitro transcription assays for mjRNAP / Katherine Smollet, Fabian Blombach, and Finn Werner -- Experimental analysis of hFACT action during pol II transcription in vitro / Fu-Kai Hsieh, Olga I. Kulaeva, and Vasily M. Studitsky -- ChIP-Seq for genome-scale analysis of bacterial DNA-binding proteins / Richard P. Bonocora and Joseph T. Wade.
  • Digital
    edited by Joana Azeredo (LIBRO- Laboratory of Research in Biofilms Rosário Oliveira, CEB- Centre of Biological Engineering, University of Minho, Braga, Portugal), Sanna Sillankorva (CEB- Centre of Biological Engineering, University of Minho, Braga, Portugal).
    Springer2018
    "This volume details the experimental approaches suitable for isolating and characterizing bacteriophages to formulating bacteriophage medicinal products and clinical application. Chapters guide readers through regulatory compliance and safety aspects of bacteriophage therapy. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Bacteriophage Therapy: From Lab to Clinical Practice aims to ensure successful results in the further study of this vital field."--Cover.
  • Digital
    edited by Martha R.J. Clokie, Andrew M. Kropinski, Rob Lavigne.
    Springer2018
    Basic phage mathematics / Stephen T. Abedon and Tena I. Katsaounis -- Analysis of host-takeover during SPO1 infection of Bacillus subtilis / Charles R. Stewart -- Practical advice on the one-step growth curve / Andrew M. Kropinski -- Iron chloride flocculation of bacteriophages from seawater / Bonnie T. Poulos, Seth G. John, and Matthew B. Sullivan -- Purification of bacteriophages using anion-exchange chromatography / Dieter Vandenheuvel, Sofie Rombouts, and Evelien M. Adriaenssens -- Encapsulation strategies of bacteriophage (Felix O1) for oral therapeutic application / Golam S. Islam, Qi Wang, and Parviz M. Sabour -- Encapsulation of listeria phage A511 by alginate to improve its thermal stability / Hanie Ahmadi, Qi Wang, Loong-Tak Lim, and S. Balamurugan -- Application of a virucidal agent to avoid overestimation of phage kill during phage decontamination assays on ready-to-eat meats / Andrew Chibeu and S. Balamurugan -- Sequencing, assembling, and finishing complete bacteriophage genomes / Daniel A. Russell -- Identification of DNA base modifications by means of pacific biosciences RS sequencing technology / Philip Kelleher, James Murphy, Jennifer Mahony, and Douwe van Sinderen -- Analyzing genome termini of bacteriophage through high-throughput sequencing / Xianglilan Zhang, Yahui Wang, and Yigang Tong -- Amplification for whole genome sequencing of bacteriophages from single isolated plaques using SISPA / Derick E. Fouts -- Genome sequencing of dsDNA-containing bacteriophages directly from a single plaque / Witold Kot -- Preparing cDNA libraries from lytic phage-infected cells for whole transcriptome analysis by RNA-Seq / Bob Blasdel, Pieter-Jan Ceyssens, and Rob Lavigne -- Essential steps in characterizing bacteriophages : biology, taxonomy, and genome analysis / Ramy Karam Aziz, Hans-Wolfgang Ackermann, Nicola K. Petty, and Andrew M. Kropinski -- Annotation of bacteriophage genome sequences using DNA master : an overview / Welkin H. Pope and Deborah Jacobs-Sera -- Phage genome annotation using the RAST pipeline / Katelyn McNair, Ramy Karam Aziz, Gordon D. Pusch, Ross Overbeek, Bas E. Dutilh, and Robert Edwards -- Visualization of phage genomic data : comparative genomics and publication-quality diagrams / Dann Turner, J. Mark Sutton, Darren M. Reynolds, Eby M. Sim, and Nicola K. Petty -- Transposable bacteriophages as genetic tools / Ariane Toussaint -- Applications of the bacteriophage mu in vitro transposition reaction and genome manipulation via electroporation of DNA transposition complexes / Saija Haapa-Paananen and Harri Savilahti -- Use of RP4 : mini-mu for gene transfer / Frederique Van Gijsegem -- Muprints and whole genome insertion scans : methods for investigating chromosome accessibility and DNA dynamics using bacteriophage mu / N. Patrick Higgins.
  • Digital/Print
    David R. Boone, Richard W. Castenholz, editors , volume one ; George M. Garrity, editor-in-chief ; editorial board, James T. Staley ... [et al.].
    Digital : Springerv. 2a 2005
    Digital : Springerv. 2b 2005
    Digital : Springerv. 2c 2005
    v. 1. The Archaea and the deeply branching and phototrophic bacteria -- v. 2. The Proteobacteria: part A. Introductory essays; part B. The Gammaproteobacteria; part C. The Alpha-, beta-, delta-, and epsilonproteobacteria -- v. 3. The Firmicutes -- v. 4. The Bacteroidetes, Spirochaetes, Tenericutes (Mollicutes), Acidobacteria, Fibrobacteres, Fusobacteria, Dictyoglomi, Gemmatimonadetes, Lentisphaerae, Verrucomicrobia, Chlamydiae, and Planctomycetes -- v. 5. The Actinobacteria.
  • Digital
    supervising editor, William B. Whitman ; editors, Paul DeVos, Jonsik Chun, Sveltlana Dedysh, Brian Hedlund, Peter Kämpfer, Fred Rainey, Martha Trujillo.
    Wiley2015
  • Digital/Print
    Gianfranco Donelli, editor.
    Digital : Springer2015
    Print2015
    The aim of this book is to provide readers with a wide overview of the main healthcare-associated infections caused by bacteria and fungi able to grow as biofilm. The recently acquired knowledge on the pivotal role played by biofilm-growing microorganisms in healthcare-related infections has given a new dynamic to detection, prevention and treatment of these infections in patients admitted to both acute care hospitals and long-term care facilities. Clinicians, hygienists and microbiologists will be updated by leading scientists on the state-of-art of biofilm-based infections and on the most innovative strategies for prevention and treatment of these infections, often caused by emerging multidrug-resistant biofilm-growing microorganisms.
  • Digital/Print
    Gianfranco Donelli, editor.
    Digital : Springer2015
    Print2015
    The aim of this book is to provide readers with a wide overview of the main healthcare-associated infections caused by bacteria and fungi able to grow as biofilm. The recently acquired knowledge on the pivotal role played by biofilm-growing microorganisms in healthcare-related infections has given a new dynamic to detection, prevention and treatment of these infections in patients admitted to both acute care hospitals and long-term care facilities. Clinicians, hygienists and microbiologists will be updated by leading scientists on the state-of-art of biofilm-based infections and on the most innovative strategies for prevention and treatment of these infections, often caused by emerging multidrug-resistant biofilm-growing microorganisms.
  • Digital
    Thomas Bjarnsholt, Peter Østrup Jensen, Claus Moser, Niels Høiby, editors.
    Springer2011
    There has been an increasing interest and emphasis on the sessile bacterial lifestyle biofilms since it was discovered that the vast majority of the total microbial biomass exists as biofilms. Leeuwenhoek first described the aggregation of bacteria in 1677, but it was only recently recognized as being important in chronic infection. In 1993, the American Society for Microbiology (ASM) recognized that the biofilm mode of growth was relevant to microbiology. This book covers both the evidence for biofilms in many chronic bacterial infections as well as the problems facing these infections such as diagnostics, pathogenesis, treatment regimes, and in vitro and in vivo models for studying biofilms. This is the first scientific book on biofilm infections, with chapters written by world- renowned scientists and clinicians. The intended audience of this book includes scientists, teachers at the university level, as well as clinicians.
  • Print
    Georg Hacker, editor
    Deconstructing the Chlamydial cell wall / Anna Klöckner [and three others] -- One face of Chlamydia trachomatis: the infectious elementary body / Mathilde M. Cossé, Richard D. Hayward and Agathe Subtil -- Manipulation of the host cell cytoskeleton by Chlamydia / Ana T. Nogueira, Antonio T. Pedrosa and Rey A. Carabeo -- Subversion of cell-autonomous host defense by Chlamydia infection / Annette Fischer and Thomas Rudel -- The hidden genomics of Chlamydia trachomatis / James Hadfield [and three others] -- Advances and obstacles in the genetic dissection of Chlamydial virulence / Julie A. Brothwell [and three others] -- Chlamydia trachomatis as the cause of infectious infertility: acute, repetitive or persistent long-term infection? / Larissa Schuchardt and Jan Rupp -- Immunopathogenesis of Chlamydial infections / Ashlesh K. Murphy, Weidang Li and Kyle H. Ramsey -- Chalmydia trachomatis: protective adaptive responses and prospects for a vaccine / Taylor B. Poston and Tone Darville.
  • Digital
    Sean Damien Gates.
    The work presented herein is concerned with the development of biophysical methodology designed to address pertinent questions regarding the behavior and structure of select pathogenic agents. Two distinct studies are documented: a shock tube analysis of endospore-laden bio-aerosols and a correlated AFM/NanoSIMS study of the structure of vaccinia virus. An experimental method was formulated to analyze the biological and morphological response of endospores to gas dynamic shock waves. A novel laser diagnostic system was implemented to provide time resolved data concerning the structural decomposition of endospores in shock-heated flows. In addition, an ex situ methodology combining viability analysis, flow cytometry and scanning electron microscopy was employed to both assess the biological response of the endospore to the shock event, as well as to provide complementary data regarding the structural state of the treated endospore. This methodology was implemented to model the shock wave induced response of a variety of Bacillus endospores. The results are subsequently synthesized into a theoretical framework to be employed in modeling the interaction of endospore-laden bio-aerosols with blast waves. An analytical method combining atomic force microscopy (AFM) and nanometer-scale secondary ion mass spectrometry (NanoSIMS) was developed to examine the spatial localization and depth distribution of specific biological elements in viral systems. This methodology was implemented to analyze the distribution of 13C labeled fatty acids as well as 15N labeled thymidine in individual nanometer sized vaccinia viral particles. Based upon the 13C and 15N signals, three-dimensional depth-resolved data regarding the architecture and localization of the virion lipid membrane and the nucleoprotein complex was generated. In addition, this methodology was employed to provide direct correlation of architectural and chemical data for isolated sub-viral structures. The technique and results presented herein represent a novel tool for the structural and chemical study of both intact viral particles as well as specifically targeted sub-viral elements.
  • Digital/Print
    Mark C. Leake, editors.
    Digital : Springer2016
    Print2016
    The biophysics of infection / Mark C. Leake -- Single-molecule observation of DNA replication repair pathways in E. coli / Adam J.M. Wollman, Aisha H. Syeda, Peter McGlynn and Mark C. Leake -- Investigating the swimming of microbial pathogens using digital holography / K.L. Thornton, R.C. Findlay, P.B. Walrad and L.G. Wilson -- What is the 'minimum inhibitory concentration' (mic) of pexiganan acting on escherichia coli?--a cautionary case study / Alys K. Jepson, Jana Schwarz-Linek, Lloyd Ryan, Maxim G. Ryadnov and Wilson C.K. Poon -- Evolution of drug resistance in bacteria / B. Waclaw -- Using biophysics to monitor the essential protonmotive force in bacteria / Mei-Ting Chen and Chien-Jung Lo -- The Type I restriction enzymes as barriers to horizontal gene transfer: determination of the DNA target sequences recognised by livestock-associated methicillin-resistant Staphylococcus aureus clonal complexes 133/ST771 and 398 / Kai Chen, Augoustinos S. Stephanou, Gareth A. Roberts, John H. White, Laurie P. Cooper, Patrick J. Houston, Jodi A. Lindsay and David T.F. Dryden -- Biomechanical analysis of infectious biofilms / David Head -- Designing a single-molecule biophysics tool for characterising DNA damage for techniques that kill infectious pathogens through DNA damage effects / Helen Miller, Adam J.M. Wollman and Mark C. Leake -- Bacterial surfaces: front lines in host-pathogen interaction / Jane E. King and Ian S. Roberts -- Biophysical approaches to bacterial gene regulation by riboswitches / Cibran Perez-Gonzalez, Jonathan P. Grondin, Daniel A. Lafontaine and J. Carlos Penedo -- Bugs on a slippery plane / Dmitri O. Pushkin and Martin A. Bees -- Transcription regulation and membrane stress management in enterobacterial pathogens / Nan Zhang, Goran Jovanovic, Christopher McDonald, Oscar Ces, Xiaodong Zhang and Martin Buck -- How biophysics may help us understand the flagellar motor of bacteria which cause infections / Matthew A.B. Baker -- Mechanics of bacterial cells and initial surface colonization / Sebastian Aguayo and Laurent Bozec -- Neutron reflectivity as a tool for physics-based studies of model bacterial membranes / Robert D. Barker, Laura E. McKinley and Simon Titmuss -- Mechanisms of Salmonella typhi host restriction / Stefania Spanò --Insights into biological complexity from simple foundations / L. Albergante, D. Liu, S. Palmer and T.J. Newman -- Force spectroscopy in studying infection / Zhaokun Zhou and Mark C. Leake -- Imaging immunity in lymph nodes: past, present and future / James Butler, Amy Sawtell, Simon Jarrett, Jason Cosgrove, Roger Leigh, Jon Timmis and Mark Coles -- Novel approaches to manipulating bacterial pathogen biofilms: whole-systems design philosophy and steering microbial evolution / Alexandra S. Penn -- Index.
  • Digital
    edited by Utpal Pal, Ozlem Buyuktanir.
    Springer2018
  • Digital
    written by Daijie Chen and Xiuping Qian ; translated from the Chinese by Qingli Hu and Youjia Hu ; illustrated by Yuankai Xue.
    World Scientific2018
    Introducing bacteria -- Friend or foe? -- A silent battle in the body -- A history of the hard and difficult war against bacteria -- A protracted tug of war -- Who will be the winner? The war continues.
  • Digital
    edited by Robert A. Britton, Baylor College of Medicine, Molecular Virology and Microbiology, Houston, Texas, Patrice D. Cani, Université catholique de Louvain, Louvain Drug Research Institute, WELBIO-Walloon Excellence in Life Sciences, Brussels, Belgium.
    Am Soc Microbiol2018
    Examining the enormous potential of microbiome manipulation to improve health.
  • Digital
    edited by James Butcher and Alain Stintzi.
    Springer2017
  • Digital
    edited by Ronald L. Cihlar and Richard A. Calderone.
    Springer2009
    Isolation of dendritic cells from human blood for in vitro interaction studies with fungal antigens / T. Sreevalsan -- Detection and quantitation of antifungal SIgA antibodies in body fluids / Michael F. Cole -- Phagocytosis and killing assays for Candida species / Chen Du and Richard A. Calderone -- Immunization protocols for use in animal models of candidiasis / Esther Segal and Hana Sandovsky-Losica -- Penetration of antifungal agents through Candida biofilms / L. Julia Douglas -- Candida biofilm analysis in the artificial throat using FISH / Bastiaan P. Krom ... [et al.] -- Conditions for optimal Candida biofilm development in microtiter plates / Bastiaan P. Krom ... [et al.] -- Animal models of candidiasis / Cornelius J. Clancy, Shaoji Cheng, and Minh H. Nguyen -- Candida albicans gene expression in an in vivo infection model / Michael D. Kruppa -- In vitro and ex vivo assays of virulence in Candida albicans / Richard A. Calderone -- Biotyping of Candida albicans and other fungi by yeast killer toxins sensitivity / Luciano Polonelli and Stephania Conti -- DNA fingerprinting Candida species / Claude Pujol and David R. Soll -- The application of tandem-affinity purification to Candida albicans / Chris Blackwell and Jeremy D. Brown -- Preparation of samples for proteomic analysis of the Candida albicans cell wall / Neeraj Chauhan -- Reporter gene assays in Candida albicans / Joy Sturtevant -- Genetic transformation of Candida albicans / Ana M. Ramon and William A. Fonzi -- Large-scale gene disruption using the UAU1 cassette / Clarissa J. Nobile and Aaaron P. Mitchell -- Standard growth media and common techniques for use with Candida albicans / Neeraj Chauhan and Michael D. Kruppa.
  • Digital
    Avigdor Schafferman, Arie Ordentlich, Baruch Velan, editors.
    Springer2010
    The Anthrax Capsule: Role in Pathogenesis and Target for Vaccines and Therapeutics / Arthur M. Friedlander -- Proteomic Studies of Bacillus anthracis Reveal In Vitro CO2-Modulation and Expression During Infection of Extracellular Proteases / Theodor Chitlaru, Orit Gat, Galia Zaide, Haim Grosfeld and Izhak Inbar, et al. -- Dynamics of Bacillus anthracis Infection and Control Mechanisms / Pierre L. Goossens, Ian J. Glomski, Lhousseine Touqui and Michèle Mock -- Survival and Trafficking of Yersinia pestis in Non-acidified Phagosomes in Murine Macrophages / James B. Bliska -- The Inverse Relationship Between Cytotoxicity of Y. pestis and Its Virulence / Emanuelle Mamroud, Avital Tidhar, Yinon Levy, Erez Bar-Haim and Gideon Halperin, et al. -- The NlpD Lipoprotein of Yersinia pestis is Essential for Cell Separation and Virulence / Avital Tidhar, Yehuda Flashner, Sara Cohen, Yinon Levy and Ayelet Zauberman, et al. -- Dissection of the Functions of the IglC Protein of Francisella tularensis / Jeanette E. Bröms, Moa Lavander and Anders Sjöstedt -- Yersinia pestis Lipopolysaccharide in Host-Pathogen Interactions / Andrey P. Anisimov, Svetlana V. Dentovskaya, Anna N. Kondakova, Buko Lindner and Rima Z. Shaikhutdinova, et al. -- The Interactions Between Pathogens and Dendritic Cells: From Paralysis of Cells to Their Recruitment for Bacterial Colonization / Baruch Velan, Erez Bar-Haim, Gal Markel, Hila Cohen and Ayelet Zauberman, et al. -- Comparative Approaches to Identify Host Factors Specifically Targeted by Yersinia pestis During the Infectious Process / Françoise Guinet, Patrick Avé, Louis Jones, Michel Huerre and Elisabeth Carniel -- Poxvirus Entry into Host Cells / Bernard Moss, Zain Bengali, Himani Bisht, Jason P. Laliberte and P.S. Satheskumar -- Role of A33R Amino-Acid 118L in the Interactions of Vaccinia Virus with the Host / Nir Paran, Shlomo Lustig, Anat Zvi, Tomer Israely and Sharon Melamed, et al. -- Inhibitors of Innate Immunity from Vaccinia Virus / Geoffrey L. Smith -- Brucella Species Synchronize Their Life Cycle to the Gestation Cycle of Their Ruminant Hosts / Svetlana Bardenstein and Menachem Banai -- MMP-9 as a Marker for Vaccinia Virus Related Encephalitis / Tomer Israely, Sharon Melamed, Noam Erez, Boaz Politi and Udy Olshevsky, et al. -- Epidemic Cowpox Virus Infections in Germany / Andreas Kurth and Andreas Nitsche -- The Two Partner Secretion Transporters of Yersinia pestis: Cloning, Immunogenicity and In Vivo Expression Following Airway Infection / Yinon Levy, Anat Zvi, Haim Grosfeld, Avital Tidhar and David Gur, et al. -- Genetic Detection of Vesicle Forming Pathogens by Arrayed Primer Extension (APEX) / Adi Beth-Din, Ofir Israeli, Ohad Shifman, Dana Stein and Einat Ben-Arie, et al. -- Subtyping Biothreat Bacterial Pathogens / Paul Keim and Talima Pearson -- A Rapid Method for Bacillus anthracis Genotyping / Haim Levy, Morly Fisher, Naomi Ariel, Shay Weiss and Anat Zvi, et al. -- Tularemia - A Disease with an Uncertain Impact on Public Health / Roland Grunow, Daniela Jacob, Andrea Kühn and Herbert Nattermann -- Consequences of Antibiotic Treatment of Francisella tularensis Airways Infections / Erez Bar-Haim, Hila Cohen, Raphael Ber, Ofer Cohen and Avigdor Shafferman -- Novel Live Vaccine Candidates Against Airborne Francisella tularensis / Wayne Conlan and Anders Sjöstedt -- Effect of Disruption of mglA on the Virulence and Immunogenicity of the Francisella tularensis Live Vaccine Strain (LVS) / Ofer Cohen, Galia Zaide, Erez Bar-Haim, Itai Mendelson and Orit Gat, et al. -- Data Mining, Bioinformatic and Immunoinformatic Analyses of Francisella tularensis Schu S4 Genome in Search for Novel Vaccine Candidates / Anat Zvi, Naomi Ariel and Avigdor Shafferman -- Modified Vaccinia Virus Ankara (MVA) based Vaccines - Immunostimulatory and Protective Capacity / Michael H. Lehmann, Melanie Kremer, Yasemin Suezer and Gerd Sutter -- Therapeutic Potential of Vaccinia Hyper Immune Sera in Mouse Models of Lethal Orthopoxviruses Infection / Sharon Melamed, Nir Paran, Tomer Israely, Noam Erez and Shaul Reuveny, et al. -- A Live Plaque Vaccine Candidate with Improved Safety and Immunogenecity / V.A. Feodorova, L.N. Pan'kina, E.P. Savostina, O.S. Kuznetsov and N.P. Konnov, et al. -- Protection Against Plague Afforded by Treatment with Polyclonal αLcrV and αF1 Antibodies / Yinon Levy, Yehuda Flashner, Ayelet Zauberman, Avital Tidhar and Moshe Aftalion, et al. -- Combination of Anthrax-Toxin Neutralizing Antibodies: Analysis of Synergism/Antagonism Effect / Ohad Mazor, Einat Ben-Arie, Adva Mechaly, Ronit Rosenfeld and Hadar Marcus, et al. -- The Efficacy of Antibiotic Treatment to Cure Guinea Pigs Intranasally Infected with Bacillus anthracis Spores / Zeev Altboum, Haim Levy, Shay Weiss, Avi Pass and Nili Rothschild, et al. -- Reverse Vaccinology in Bacillus anthracis / Avigdor Shafferman, Orit Gat, Naomi Ariel, Theodor Chitlaru and Haim Grosfeld, et al.
  • Digital
    Esteban Toro Gomez.
    Bacterial chromosomes are generally ~1000 times longer than the cells in which they reside, and concurrent replication, segregation, and transcription/translation of this crowded mass of DNA poses a challenging organizational problem. At first, it was assumed that DNA is organized randomly inside the cell, much like a bowl of spaghetti. Furthermore, it was argued that segregation of this disordered mass was not carried out by a mitotic machinery as is found in eukaryotes, but rather the by-product of cell growth. Hence, the canonical description of bacterial DNA was that of an unstructured polymer diffusing randomly. Recent advances in cell imaging technology, however, have revealed that the bacterial nucleoid is reliably oriented and highly organized within the cell. Furthermore, the speed of segregation is inconsistent with the old model driven by cell growth. Here, I use a screening approach to identify parS, a 100bp piece of DNA previously found to be anchored to the old cell pole, as the Caulobacter centromere. In direct contrast to other published models, parS segregates ahead of all other sequences, including the origin of replication (Cori), and moving parS away from Cori causes segregation -- but not replication -- to be delayed. The segregation of parS requires the ATPase activity of the ParA protein, and current work is aimed at understanding the molecular details of this process. All of these data point to the presence of an active, mitotic-like machine that drives chromosome segregation in Caulobacter. I also show that the circular Caulobacter chromosome is oriented in relation to the parS anchor site at the old cell pole, so that changing the genomic position of parS causes the entire chromosome to rotate within the cell. Finally, I find that the chromosome is organized into a dense core running down the length of the cell, and I arrive at two possible models for the large-scale structure of this core. Thus, this work forms part of an emerging view of the chromosome as a highly organized structure that is kept in place by simple yet active mechanisms, and whose segregation is insured by a complex dedicated machine.
  • Digital
    editors, Glenn S. Tillotson, Karl Weiss.
    Future Med2013
    Clostridium difficile : new challenges for an old foe / Glenn S. Tillotson & Karl Weiss -- Clostridium difficile infection : a global threat / Nuttanun Suramaethakul & Teena Chopra -- Pathogenicity mechanisms of Clostridium difficile / Mark M. Collery, Revathi Govind, Nigel P. Minton & Sarah A. Kuehne -- Immunology and Clostridium difficile / Ciarán P. Kelly & Saurabh Sethi -- The microbiome and Clostridium difficile infection / Charles Y. Chiu & Dylan R. Pillai -- Economic burden of Clostridium difficile infection / Samuel L. Aitken, Dhara N. Shah & Kevin W. Garey -- Laboratory diagnosis of Clostridium difficile infection / Peter H. Gilligan -- Conventional therapeutics for Clostridium difficile infection / Jessica Martin & Mark Wilcox -- Infection control issues in Clostridium difficile / Scott Curry -- Future and alternative approaches to managing Clostridium difficile infection / Glenn S. Tillotson & Karl Weiss -- Recent advances with Clostridium difficile / Joni Tillotson & Glenn S. Tillotson -- Index.
  • Digital
    Andreas Burkovski, editor.
    Springer2014
    Corynebacterium diphtheriae is the classical etiological agent of diphtheria and the type strain of the genus Corynebacterium. While diphtheria of the respiratory tract became rare with the introduction of vaccination programs in industrialized countries, even today several thousand cases per year are reported to the World Health Organization. This shows that diphtheria is not completely eradicated and that reservoirs exist. The book summarizes the latest advances made in understanding C. diphtheriae and the closely related species Corynebacterium ulcerans and Corynebacterium pseudotuberculosis. Topics addressed are genomics of toxigenic corynebacteria, host-pathogen-interaction, detection, surveillance and treatment as well as application aspects.
  • Digital
    Hideaki Yukawa, Masayuki Inui, editors.
    Springer2013
    Corynebacterium glutamicum was discovered in Japan in 1956 as a natural glutamate producer. Its "microbial factory" qualities, such as its physiological plasticity and robust catalytic functionalities, have since facilitated the development of efficient production processes for amino acids, nucleotides and vitamins. This monograph illustrates how the information gleaned from complete genome sequencing allows the rational engineering of the entire cellular metabolism and how systems biology permits the further optimization of C. glutamicum as a biocatalyst. Aspects of gene regulation, metabolic pathways, sugar uptake, protein secretion, cell division and biorefinery applications highlight the enormous biotechnological and biorefinery potential.
  • Digital/Print
    Rudolf Toman ... [et al.], editors.
    Digital : Springer2012
    Print2012
    History and Prospects of Coxiella burnetii Research / Karim E. Hechemy -- Phylogenetic Diversity, Virulence and Comparative Genomics / Erin J. van Schaik and James E. Samuel -- Defense Mechanisms Against Oxidative Stress in Coxiella burnetii: Adaptation to a Unique Intracellular Niche / Katja Mertens and James E. Samuel -- Lipopolysaccharide of Coxiella burnetii / Craig T. Narasaki and Rudolf Toman -- Components of Protective Immunity / Guoquan Zhang, Yan Zhang and James E. Samuel -- Proteome of Coxiella burnetii / Robert Ihnatko, Edward Shaw and Rudolf Toman -- Coxiella Subversion of Intracellular Host Signaling / S. Kauser Hussain and Daniel E. Voth -- The Coxiella burnetii Parasitophorous Vacuole / Eric Ghigo, María I. Colombo and Robert A. Heinzen -- Coxiella burnetii Secretion Systems / Justin A. McDonough, Hayley J. Newton and Craig R. Roy -- Role of Lipids in Coxiella burnetii Infection / Stacey D. Gilk -- Axenic Growth of Coxiella burnetii / Anders Omsland -- Developmental Biology of Coxiella burnetii / Michael F. Minnick and Rahul Raghavan -- Genetic Manipulation of Coxiella burnetii / Paul A. Beare -- Role of Innate and Adaptive Immunity in the Control of Q Fever / Christian Capo and Jean-Louis Mege -- Immune Response and Coxiella burnetii Invasion / Amira Ben Amara, Yassina Bechah and Jean-Louis Mege -- Antigenic Analysis for Vaccines and Diagnostics / Laura R. Hendrix and Chen Chen -- Epidemic Q Fever in Humans in the Netherlands / Wim van der Hoek, Gabriëlla Morroy, Nicole H. M. Renders, Peter C. Wever and Mirjam H. A. Hermans, et al. -- Coxiella-like Endosymbionts / Jianmin Zhong -- Molecular Typing of Coxiella burnetii (Q Fever) / Robert F. Massung, Sally J. Cutler and Dimitrios Frangoulidis.
  • Digital
    edited by Garth D. Ehrlich, Patrick J. DeMeo, J. William Costerton, Heinz Winkler.
    Springer2012
    During the recent transition between acute diseases caused by swarms of single planktonic bacteria, and chronic infections caused by bacteria growing in slime-enclosed biofilms, a general clinical consensus has emerged that pathologies with bacterial etiologies are frequently culture negative. Because biofilm infections now affect 17 million Americans per year (killing approximately 450,000), the suggestion that these common and lethal infections regularly go unnoticed by the only FDA-approved method for their detection and characterization is a matter of urgent concern. Biologically, we would expect that planktonic bacterial cells would colonize any new surface, including the surface of an agar plate, while the specialized sessile cells of a biofilm community would have no such proclivity. In the study of biofilm diseases ranging from otitis media to prostatitis, it was found that direct microscopy and DNA- and RNA-based molecular methods regularly document the presence of living bacteria in tissues and samples that are culture negative. The editors selected orthopedic biofilm infections as the subject of this book because these infections occur against a background of microbiological sterility in which modern molecular methods would be expected to find bacterial DNA, RNA-based microscopic methods would be expected to locate bacterial cells, and cultures would be negative. Moreover, in Orthopedics we find an already biofilm-adapted surgical group in which current strategies are based on the meticulous removal of compromised tissues, antibiotic options as based on high biofilm-killing local doses, and there are practical bedside strategies for dealing with biofilm infections. So here is where the new paradigm of biofilm infection meets the equally new paradigm of the culture negativity of biofilms, and this volume presents a conceptual synthesis that may soon combine the most effective molecular methods for the detection and identification of bacteria with a surgical discipline that is ready to help patients.
  • Digital
    edited by Kimberly A. Bishop-Lilly.
    Springer2017
    Whole-genome enrichment using RNA probes and sequencing of Chlamydia trachomatis directly from clinical samples / Amanda Claire Brown and Mette T. Christiansen -- Characterization of sinus microbiota by 16S sequencing from swabs / Thad W. Vickery, Jennifer M. Kofonow, and Vijay R. Ramakrishnan -- Molecular subtyping of Salmonella typhimurium with multiplex oligonucleotide ligation-PCR (MOL-PCR) / Véronique Wuyts, Wesley Mattheus, Nancy H.C. Roosens, Kathleen Marchal, Sophie Bertrand, and Sigrid C.J. De Keersmaecker -- Detection of Helicobacter pylori DNA in formalin-fixed paraffin-embedded gastric biopsies using laser microdissection and qPCR / María Fernanda Loayza Villa, Valeria Liliana Herrera Sevilla, and Nicolás Vivar-Diaz -- Mycobacterial load assay / Stephen H. Gillespie, Wilber Sabiiti, and Katarina Oravcova -- Defining diagnostic biomarkers using shotgun proteomics and MALDI-TOF mass spectrometry / Jean Armengaud -- Detection and typing of "Candidatus Phytoplasma" spp. in host DNA extracts using oligonucleotide-coupled fluorescent microspheres / Edel Pérez-López, Christine Hammond, Chrystel Olivier, and Tim J. Dumonceaux -- Detection of Helicobacter pylori in the gastric mucosa by fluorescence in vivo hybridization / Silvia Fontenete, Marina Leite, Ceu Figueiredo, Paul Cos, and Nuno F. Azevedo -- Rapid antibiotic susceptibility testing for urinary tract infections / Anja Mezger, Mats Nilsson, and Dan I. Andersson -- Detection and differentiation of lyme spirochetes and other tick-borne pathogens from blood using real-time PCR with molecular beacons / Samantha Schlachter, Kamfai Chan, Salvatore A.E. Marras, and Nikhat Parveen -- Methods for real-time PCR-based diagnosis of Chlamydia pneumoniae, Chlamydia psittaci, and Chlamydia abortus infections in an opened molecular diagnostic platform / Onya Opota, René Brouillet, Gilbert Greub, and Katia Jaton -- Real-time PCR to identify Staphylococci and assay for virulence from blood / Charles E. Okolie -- Multiplex peptide nucleic acid fluorescence in situ hybridization (PNA-FISH) for diagnosis of bacterial vaginosis / Antonio Machado and Nuno Cerca -- Closed-tube loop-mediated isothermal amplification assay for the visual endpoint detection of Brucella spp. and Mycobacterium avium subsp. paratuberculosis / Marcos D. Trangoni, Andrea K. Gioffré, and Silvio L. Cravero -- Highly specific ligation-dependent microarray detection of single nucleotide polymorphisms / Noa Wolff and Ivan Barišicʹ -- Multilocus sequence typing (MLST) for Cronobacter spp / Susan Joseph and Stephen Forsythe -- Diagnostic bacteriology : raman spectroscopy / Rebecca L. Pavlicek, Nicole J. Crane, Meron Ghebremedhin, Katherine E. Cilwa, and Eric A. Elster.
  • Digital
    Xiaoyuan Wang, Peter J. Quinn, editors.
    Springer2010
    Endotoxins: Lipopolysaccharides of Gram-negative bacteria / X. Wang and P.J. Quinn -- Purification and characterization of lipopolysaccharides / X. Wang ... [et al.] -- Endotoxins: Relationship between structure, function, and activity / K. Brandenburg, A.B. Schromm and T. Gutsmann -- The diversity of the core oligosaccharide in lipopolysaccharides / A. Silipo and A. Molinaro -- Salmonella-regulated lipopolysaccharide modifications / S.M. Richards, K.L. Strandberg and J.S. Gunn -- The variation of O antigens in Gram-negative bacteria / L. Wang, Q. Wang and P.R. Reeves -- Regulators of TLR4 signaling by endotoxins / A.F. McGettrick and L.A.J. O'Neill -- Membrane partitioning: Is location everything when it comes to endotoxin recognition? / M. Triantafilou and K. Triantafilou -- Endotoxin detection - from limulus amebocyte lysate to recombinant Factor C / J.L. Ding and B. Ho -- The role of endotoxin in infection: Helicobacter pylori and Campylobacter jejuni / A.P. Moran -- The role of pseudomonas lipopolysaccharide in cystic fibrosis airway infection / S.M. Moskowitz and R.K. Ernst -- Development of small-molecule endotoxin sequestering agents / S.A. David and D. Sil -- Development of an anti-endotoxin vaccine for sepsis / A.S. Cross -- Synthetic and natural TLR4 agonists as safe and effective vaccine adjuvants / C.B. Fox ... [et al.] -- Targeting endotoxin in the treatment of sepsis / J.-S. Rachoin, C.A. Schorr and R.P. Dellinger -- Lipopolysaccharides in rhizobium-legume symbioses / R.W. Carlson, L.S. Forsberg and E.L. Kannenberg -- Lipopolysaccharides and plant innate immunity / G. Erbs ... [et al.].
  • Digital
    prepared by ECRI Institute ; prepared for Agency for Healthcare Research and Quality, U.S. Department of Health and Human Services.
  • Digital/Print
    Digital : WHO2012
    Print2012
    Chapter 1. The evolving threat of antimicrobial resistance: Introduction -- Chapter 2. Surveillance to track antimicrobial use and resistance in bacteria -- Chapter 3. Measures to ensure better use of antibiotics -- Chapter 4. Reducing antimicrobial use in animal husbandry -- Chapter 5. Infection prevention and control in health-care facilities -- Chapter 6. Fostering innovation to combat antimicrobial resistance -- Chapter 7. The way forward: political commitment to enable options for action -- Appendix 1. List of 2001 WHO Global Strategy for Containment of Antimicrobial Resistance recommendations -- Appendix 2. List of 2011 WHO World Health Day six-point policy briefs.
  • Digital
    Sikha Mandal, Jnanendra Rath.
    Springer2015
    This volume presents recent developments in the novel drug development and potential of extremophilic cyanobacteria. It discusses how these tiny organism originated, produce oxygen that leads to evolution of life on the earth, how their survival strategies in extreme climatic conditions lead to diverse metabolic pathways, and the opportunity to use them to develop novel drugs. The book is comprised of five chapters, starting with the origin of cyanobacteria, their survival strategies under extreme conditions, and their capabilities to change metabolic activities.The second chapter explores the different metabolic pathways found in cyanobacteria and examines advances in this field and recent techniques like MALDI-TOF imaging and metagenomics tools as well as in silico techniques for rapid screening of secondary metabolites. Further chapters cover the glycomics of cyanobacteria, anticancer drug development, and some issues and challenges of using cyanobacteria to develop drugs. Extremophilic Cyanobacteria For Novel Drug Development provides insight into future perspectives in drug development and is a key resource for students, researchers and professionals in pharmacy, medicinal chemistry, pharmacognosy biotechnology, biology, and academics.
  • Digital
    Essam Kotb.
    Springer2012
  • Digital
    Arun K. Bhunia.
    Springer2008
  • Digital
    Peter Zuber.
    Springer2013
    This SpringerBrief on Spx reviews the investigations that led to the discovery of Spx and its orthologs and ties together the results of various studies that have explored the function and control of spx in Gram-positive organisms. Spx of Bacillus subtilis has been extensively studied, but very little has been published about it. This book incorporates a number of studies that have been conducted in other Gram positive bacteria, which examined the role of Spx orthologs in stress response, bacterial development and virulence. The book contains an overview that will introduce the protein and its orthologous forms, its association with RNA polymerase, the species of Gram-positive bacteria in which it is found, and the conditions in which it is abundant and active. Spx is a member of a large group of proteins belonging to the ArsC/Spx protein family, so the review touches upon the bioinformatic support for the protein family composition and its meaning with regard to protein structure/function.
  • Digital
    edited by Jeffrey L. Bose.
    Springer2016
    Understanding staphylococcal nomenclature / Christina N. Krute and Jeffrey L. Bose -- Restriction-modification systems as a barrier for genetic manipulation of Staphylococcus aureus / Marat R. Sadykov -- Complementation plasmids, inducible gene-expression systems, and reporters for Staphylococci / Ralph Bertram -- De novo assembly of plasmids using yeast recombinational cloning / Ameya A. Mashruwala and Jeffrey M. Boyd -- Splicing by overlap extension PCR to obtain hybrid DNA products / Justin A. Thornton -- Method for preparation and electroporation of S. aureus and S. epidermidis / Melinda R. Grosser and Anthony R. Richardson -- Rapid isolation of DNA from staphylococcus / Kelsey L. Krausz and Jeffrey L. Bose -- Bacteriophage transduction in Staphylococcus aureus : broth-based method / Kelsey L. Krausz and Jeffrey L. Bose -- Bacteriophage transduction in Staphylococcus aureus / Michael E. Olson -- Batch transduction of transposon mutant libraries for rapid phenotype screening in staphylococcus / Katherine L. Maliszewski -- Conjugative transfer in Staphylococcus aureus / Cortney R. Halsey and Paul D. Fey -- Allelic exchange / McKenzie K. Lehman, Jeffrey L. Bose, and Kenneth W. Bayles -- Creation of staphylococcal mutant libraries using transposon Tn917 / Kelly C. Rice -- Generation of a transposon mutant library in Staphylococcus aureus and staphylococcus epidermidis using bursa aurealis / Vijaya Kumar Yajjala ... [et al.] -- Chemical and UV mutagenesis / Jeffrey L. Bose -- Pulse field gel electrophoresis / Batu K. Sharma-Kuinkel, Thomas H. Rude, and Vance G. Fowler Jr. -- RNA-sequencing of Staphylococcus aureus messenger RNA / Ronan K. Carroll, Andy Weiss, and Lindsey N. Shaw -- Quantitative real-time PCR (qPCR) workflow for analyzing Staphylococcus aureus gene expression / April M. Lewis and Kelly C. Rice -- Electrophoretic mobility shiftaAssays / Sarah E. Rowe and James P. O'Gara -- Rapid amplification of cDNA ends for RNA transcript sequencing in staphylococcus / Eric Miller.
  • Digital
    Sheela Srivastava.
    Springer2013
    Described as the earliest, simplest life forms, with unlimited metabolic versatility, bacteria are ideally suited to answer some very fundamental questions on life and its processes. They have been employed in almost all fields of biological studies, including Genetics. The whole edifice of science of Genetics centers around three processes: the generation, expression, and transmission of biological variation, and bacteria offer immediate advantages in studying all the three aspects of heredity. Being haploid and structurally simple, it becomes easy to isolate mutations of various kinds and relate them to a function. The availability of such mutants and their detailed genetic and biochemical analyses lead to a gamut of information on gene expression and its regulation. While studying the transmission of biological variation, it is clear that unlike their eukaryotic counterpart, a more genetic approach needs to be employed. Transmission of genetic information in most eukaryotic organisms rests on sexual reproduction that allows the generation of genetically variable offspring through the process of gene recombination. Even though bacteria show an apparent preference for asexual reproduction, they too have evolved mechanisms to trade their genetic material. In fact, bacteria not only could acquire many genes from close relatives, but also from entirely distant members through the process of horizontal gene transfer. Their success story of long evolutionary existence will stand testimony to these mechanisms. While teaching a course on Microbial Genetics to the post-graduate students at Delhi University, it was realized that a book devoted to bacterial genetics may be very handy to the students, researchers, and teachers alike. A strong foundation in genetics also helps in comprehending more modern concepts of molecular biology and recombinant DNA technology, always a favorite with the students and researchers. Planning the format of the book, emphasis has been laid on the generation and transmission of biological variability. The omission of expression part is indeed intentional because lots of information is available on this aspect in any modern biology book. The contents are spread over seven chapters and the text is supported with figures/tables wherever possible. The endeavor has been to induce the readers to appreciate the strength of bacterial genetics and realize the contribution of these tiny organisms to the growth of biological sciences as a whole and genetics in particular.
  • Digital
    Vijaykumar Yogesh Muley, Vishal Acharya.
    Springer2013
    Introduction -- From genomes to protein functions -- Co-evolutionary signals within genome sequences reflect functional dependence of proteins -- Chromosomal proximity of genes as an indicator of functional linkage -- Analyses of complex genome-scale biological networks -- Application of protein interaction networks.
  • Digital
    edited by Trenton R. Schoeb, Kathryn A. Eaton.
    ScienceDirect2017
  • Digital
    edited by Vincent A. Fischetti, Richard P. Novick, Joseph J. Ferretti, Daniel A. Portnoy, Miriam Braunstein, and Julian Rood.
    Am Soc Microbiol2019
  • Digital
    W. Joost Wiersinga, Christopher W. Seymour, editors.
    Springer2018
    This practically oriented book provides an up-to-date overview of all significant aspects of the pathogenesis of sepsis and its management, including within the intensive care unit. Readers will find information on the involvement of the coagulation and endocrine systems during sepsis and on the use of biomarkers to diagnose sepsis and allow early intervention. International clinical practice guidelines for the management of sepsis are presented, and individual chapters focus on aspects such as fluid resuscitation, vasopressor therapy, response to multiorgan failure, antimicrobial therapy, and adjunctive immunotherapy. The closing section looks forward to the coming decade, discussing novel trial designs, sepsis in low- and middle-income countries, and emerging management approaches. The book is international in scope, with contributions from leading experts worldwide. It will be of value to residents and professionals/practitioners in the fields of infectious diseases and internal medicine, as well as to GPs and medical students.
  • Digital
    edited by Nicola A. Burgess-Brown.
    Springer2017
    Recombinant protein expression in E. coli : a historical perspective / Opher Gileadi -- N- and C-terminal truncations to enhance protein solubility and crystallization : predicting protein domain boundaries with bioinformatics tools / Christopher D.O. Cooper and Brian D. Marsden -- Harnessing the profinity eXact system for expression and purification of heterologous proteins in E. coli / Yoav Peleg, Vadivel Prabahar, Dominika Bednarczyk, and Tamar Unger -- ESPRIT : a method for defining soluble expression constructs in poorly Understood Gene Sequences / Philippe J. Mas and Darren J. Hart -- Optimizing expression and solubility of proteins in E. coli using modified media and induction parameters / Troy Taylor, John-Paul Denson, and Dominic Esposito -- Optimization of membrane protein production using titratable strains of E. coli / Rosa Morra, Kate Young, David Casas-Mao, Neil Dixon, and Louise E. Bird -- Optimizing E. coli-based membrane protein production using Lemo21(DE3) or pReX and GFP-fusions / Grietje Kuipers, Markus Peschke, Nurzian Bernsel Ismail, Anna Hjelm, Susan Schlegel, David Vikström, Joen Luirink, and Jan-Willem de Gier -- High yield of recombinant protein in shaken E. coli cultures with enzymatic glucose release medium EnPresso B / Kaisa Ukkonen, Antje Neubauer, Vinit J. Pereira, and Antti Vasala -- Generic protocol for purifying disulfide-bonded domains and random protein fragments using fusion proteins with SUMO3 and cleavage by SenP2 protease / Hüseyin Besir -- Strategy for production of correctly folded disulfide-rich peptides in the periplasm of E. coli / Natalie J. Saez, Ben Cristofori-Armstrong, Raveendra Anangi, and Glenn F. King -- Split GFP complementation as reporter of membrane protein expression and stability in E. coli : a tool to engineer stability in a LAT transporter / Ekaitz Errasti-Murugarren, Arturo Rodríguez-Banqueri, and José Luis Vázquez-Ibar -- Acting on folding effectors to improve recombinant protein yields and functional quality / Ario de Marco -- Protein folding using a vortex fluidic device / Joshua Britton, Joshua N. Smith, Colin L. Raston, and Gregory A. Weiss -- Removal of affinity tags with TEV protease / Sreejith Raran-Kurussi, Scott Cherry, Di Zhang, and David S. Waugh -- Generation of recombinant n-linked glycoproteins in E. coli / Benjamin Strutton, Stephen R.P. Jaffé, Jagroop Pandhal, and Phillip C. Wright -- Production of protein kinases in E. coli / Charlotte A. Dodson -- Expression of prokaryotic integral membrane proteins in E. coli / James D. Love -- Multiprotein complex production in E. coli : the SecYEG-SecDFYajC-YidC holotranslocon / Imre Berger, Quiyang Jiang, Ryan J. Schulze, Ian Collinson, and Christiane Schaffitzel -- Membrane protein production in E. coli lysates in presence of preassembled nanodiscs / Ralf-Bernhardt Rues, Alexander Gräwe, Erik Henrich, and Frank Bernhard -- Not limited to E. coli : versatile expression vectors for mammalian protein expression / Katharina Karste, Maren Bleckmann, and Joop van den Heuvel -- Generic protocol for intracellular expression of recombinant proteins in Bacillus subtilis / Trang Phan, Phuong Huynh, Tuom Truong, and Hoang Nguyen -- In vivo biotinylation of antigens in E. coli / Susanne Gräslund, Pavel Savitsky, and Susanne Müller-Knapp -- Cold-shock expression system in E. coli for protein NMR studies / Toshihiko Sugiki, Toshimichi Fujiwara, and Chojiro Kojima -- High-throughput production of proteins in E. coli for structural studies / Charikleia Black, John J. Barker, Richard B. Hitchman, Hok Sau Kwong, Sam Festenstein, and Thomas B. Acton -- Mass spectrometric analysis of proteins / Rod Chalk -- How to determine interdependencies of glucose and lactose uptake rates for heterologous protein production with E. coli / David J. Wurm, Christoph Herwig, and Oliver Spadiut -- Interfacing biocompatible reactions with engineered Escherichia coli / Stephen Wallace and Emily P. Balskus.
  • Digital
    [edited by] Giuseppe Micali.
    Wiley2017
    Epidemiology and pathogenesis / Vincenzo Bettoli and Giulia Ruina -- Clinical features and diagnostic clues / Maria Letizia Musumeci, Maria Rita Nasca, Piera Catalfo, Karishma Bhatt, and Giuseppe Micali -- Histopathology / Franco Rongioletti -- Classification and severity scales / Giuseppe Monfrecola and Matteo Megna -- Correlation between severity and its impact on quality of life / Nevena Skroza and Maria Concetta Potenza -- Comorbidities and complex syndromes / Gabriella Fabbrocini and Valerio De Vita -- Complications / Teresa Oranges, Valentina Dini, Andrea Chiricozzi, Salvatore Panduri, and Marco Romanelli -- Ultrasound imaging / Antonio Martorell -- Radiological imaging / Giuseppe Petrillo, Stefano Palmucci, and Claudia Trombatore -- Skin imaging : dematoscopy and videodermatoscopy / Francesco Lacarrubba, Anna Elisa Verzì, Federica Fiorentini, and Giuseppe Micali -- Differential diagnosis / Stefano Veraldi, Elena Guanziroli, and Mauro Barbareschi.
  • Print
    editors, Alexa B. Kimball, Gregor B.E. Jemec.
    Springer2017
    A concise but comprehensive pocket handbook that provides an accessible and up-to-date introductory overview of this debilitating skin disease. Written by highly recognizable leaders in the field, this book presents essential information on the pathophysiology, clinical presentation, diagnosis and management strategies and options for hidradenitis suppurativa, forming an ideal resource to increase awareness of this disease among healthcare professionals.
  • Digital/Print
    Thomas J. Inzana, editor.
    Digital : Springer2016
    Print2016
    Taxonomy of Histophilus somni -- Histophilosis as a Natural Disease -- Histophilus somni Genomics and Genetics -- Interactions on Histophilus somni with Host Cells -- Histophilus somni Surface Proteins -- Host Immune Response to Histophilus somni -- The Many Facets of Lipooligosaccharide as a Virulence Factor of Histophilus somni -- Exopolysaccharide Production and Biofilm Formation by Histophilus somni.
  • Digital
    edited by Gottfried Unden, Eckhard Thines, and Anja Schüffler.
    Wiley2016
    Adaptation of Microbial Metabolism in Host/Pathogen Interaction. Metabolic Adaptation of Human Pathogenic / Ann Kathrin Heroven, Petra Dersch -- Crosstalk between Metabolism and Virulence of / Klaus Heuner, Wolfgang Eisenreich -- Metabolism of Intracellular / Peter Holtkötter, Michael Hensel -- The Human Microbiome in Health and Disease / Cian Hill, R Paul Ross, Catherine Stanton, Paul W O'Toole -- Mechanisms of Dysbiosis in the Inflamed Gut / Sebastian E Winter -- Strategies for Nutrient Acquisition by during the Infection of Rice / Andrew J Foster, George R Littlejohn, Darren M Soanes, Nicholas J Talbot -- New Inhibitors and Targets of Infectious Diseases. Outer Membrane Proteins as Potential Anti-infective Drug Targets in / Robert L Davies -- Identification of Anti-infective Compounds Using Amoebae / Christopher F Harrison, Hubert Hilbi -- Stress Biology in Fungi and "Omic" Approaches as Suitable Tools for Analyzing Plant-Microbe Interactions / Stefan Jacob, Alexander Yemelin -- Targeting Plasmids: New Ways to Plasmid Curing / Anja Schüffler, Corinna Kübler -- Regulation of Secondary Metabolism in the Gray Mold Fungus / Muriel Viaud, Julia Schumacher, Antoine Porquier, Adeline Simon.
  • Digital
    edited by Carlos Medina, Francisco Javier López-Baena.
    Springer2018
  • Digital/Print
    G. Singh Chhatwal, editor.
    Digital : Springer2013
    Print2013
    Streptococci are Gram-positive bacteria that cause a wide spectrum of diseases, such as pharyngitis, necrotizing fasciitis and streptococcal toxic shock syndrome, as well as rheumatic fever and rheumatic heart disease as sequelae. Antibiotics alone have not been able to control the disease and in spite of many efforts an effective vaccine is not yet available. A prerequisite for novel and successful strategies for combating these bacteria is a complete understanding of the highly complex pathogenic mechanisms involved, which are analyzed in this volume. In ten chapters, prominent authors cover various aspects including streptococcal diseases and global burden, epidemiology, adaptation and transmission, and molecular mechanisms of different diseases, as well as sequelae, vaccine development and clinical management. This book will serve as a valuable reference work for scientists, students, clinicians and public health workers and provide new approaches to meeting the challenge of streptococcal diseases.
  • Digital/Print
    Nigel Curtis, Adam Finn, Andrew J. Pollard, editors.
    Digital : Springer2013
    Print2013
  • Digital/Print
    Adam Finn, Nigel Curtis, Andrew J. Pollard, editors.
    Digital : Springer2010
    Print2010
  • Digital/Print
    Nigel Curtis, Adam Finn, Andrew J. Pollard, editors.
    Digital : Springer2011
    Print2011
    The value of vaccination / David E. Bloom -- Recent trends in global immunisation / Gustav J.V. Nossal -- New advances in typhoid fever vaccination strategies / Zulfiqar A. Bhutta ... [et al.] -- Prevention of vertical transmission of HIV in resource-limited countries / Catherine M. Wilfert ... [et al.] -- Pneumonia in children in developing countries / Frank Shann -- Darwin, microbes and evolution by natural selection / E. Richard Moxon -- Human herpesvirus 6 / Charles G. Prober -- Advances in the diagnosis and management of central venous access device infections in children / Asha Bowen and Jonathan Carapetis -- Moraxella catarrhalis-pathogen or commensal? / Christoph Aebi -- Anaerobic infections in children / Itzhak Brook -- Encephalitis diagnosis and management in the real world / Sarah S. Long -- Toxic shock syndrome-evolution of an emerging disease / James K. Todd -- Dissection of B-cell development to unravel defects in patients with a primary antibody deficiency / Mirjam van der Burg ... [et al.] -- Mumps is back : why is mumps eradication not working? / Noni Macdonald ... [et al.] -- Neonatal herpes simplex virus infections: where are we now? / Clara Thompson and Richard Whitley -- Rational approach to pediatric antifungal therapy / William J. Steinbach -- Antiviral therapy of CMV disease in children / Mike Sharland ... [et al.] -- Infectious hazards from pets and domestic animals / Mona Al-Dabbagh and Simon Dobson -- Novel technology to study co-evolution of humans and Staphylococcus aureus: consequences for interpreting the biology of colonisation and infection / Alex van Belkum -- A practical approach to eosinophilia in a child arriving or returning from the tropics / Penelope Bryant and Nigel Curtis.
  • Digital/Print
    Nigel Curtis, Adam Finn, Andrew J. Pollard, editors.
    Digital : Springer2011
    Print2011
    Our Time of Pestilence: Purchasing Immunity and Ignoring the Misery of Others / Philip Alcabes -- Neonatal Meningitis: Can We Do Better? / Paul T. Heath, Ifeanyichukwu O. Okike and Clarissa Oeser -- Approaches Towards Avoiding Lifelong Antiretroviral Therapy in Paediatric HIV Infection / Philip J. R. Goulder and Andrew J. Prendergast -- How Short Is Long Enough for Treatment of Bone and Joint Infection? / Markus Pääkkönen and Heikki Peltola -- What's New in Diagnostic Testing and Treatment Approaches for Mycoplasma pneumoniae Infections in Children? / Ken B. Waites -- Pigs, Poultry, and Pandemic Influenza: How Zoonotic Pathogens Threaten Human Health / Thijs Kuiken, Ron Fouchier, Guus Rimmelzwaan, Judith van den Brand and Debby van Riel, et al. -- Kingella kingae Infections in Children: An Update / Inbal Weiss-Salz and Pablo Yagupsky -- Influenza Pandemics / Ruth Elderfield and Wendy Barclay -- Management of Shunt Related Infections / Mona Al-Dabbagh and Simon Dobson -- Nontuberculous Lymphadenopathy in Children: Using the Evidence to Plan Optimal Management / Julia E. Clark -- Pediatric Brucellosis: An (Almost) Forgotten Disease / Pablo Yagupsky -- Q Fever: Still More Queries than Answers / Corine E. Delsing, Adilia Warris and Chantal P. Bleeker-Rovers -- Rickettsioses in Children: A Clinical Approach / Emmanouil Galanakis and Maria Bitsori -- What is the Evidence Behind Recommendations for Infection Control? / Christina Gagliardo and Lisa Saiman -- What Do We Know About How to Treat Tuberculosis? / Ben J. Marais -- Bacterial Meningitis in Childhood / Manish Sadarangani and Andrew J. Pollard -- Mycobacterium marinum Infection / Marc Tebruegge and Nigel Curtis.
  • Digital/Print
    Marc Stadler, Petra Dersch, editors.
    Digital : Springer2016
    Print2016
    Tackling threats and future problems of multidrug-resistant bacteria.-Emergence and spread of antimicrobial resistance: recent insights from bacterial population genomics -- Epidemiology of Staphylococcus aureus nasal carriage patterns in the community -- Diagnostics and resistance profiling of bacterial pathogens -- Use of antibiotics and antimicrobial resistance in veterinary medicine as exemplified by the swine pathogen Streptococcus suis.-Antibiotics and the intestinal microbiome: individual responses, resilience of the ecosystem and the susceptibility to infections -- Anti-virulence strategies to target bacterial infections -- Strategies to block bacterial pathogenesis by interference with motility and chemotaxis -- New horizons in the development of novel needle-free immunization strategies to increase vaccination efficacy -- History of antibiotics research -- Actinobacteria and Myxobacteria -- Two of the most important bacterial resources for novel antibiotics -- Exploitation of fungal biodiversity for discovery of novel antibiotics -- Strategies for the discovery and development of new antibiotics from natural products: Three Case Studies -- New structural templates for clinically validated and novel targets in antimicrobial drug research and development -- Synthesis of antibiotics -- Antibiotics clinical development and pipeline -- Anti-infectives in drug delivery -- overcoming the Gram-negative bacterial cell envelope.
  • Digital
    edited by Colin Harwood and Grant J. Jensen.
    ScienceDirect2016
    Section 1. Fluorescent microscopy -- Methods for visualization of peptidoglycan biosynthesis -- Time-lapse microscopy and image analysis of Escherichia coli cells in mother machines -- Microfluidics for bacterial imaging -- Section 2. Electron microscopy -- Electron cryotomography.
  • Digital
    edited by Michael Vajdy.
    Springer2008
  • Digital
    Andrew W. Artenstein.
    Springer2013
    1. Origins -- 2. The Art and Science of Germs -- 3. A Singular Disease -- 4. A Very Mortal Disease -- 5. Early Approaches at Therapy -- 6. Antibiotics and Survival of the Fittest -- 7. A Brief History of Vaccines -- 8. That Soluble Specific Substance -- 9. Towards a Vaccine -- 10. Success for Half -- 11. The Future of a Killer.
  • Digital
    editors, W. Michael Scheld, Richard J. Whitley, Christina M. Marra.
    Ovid2014
    "This clinical reference on central nervous system infections is now in its thoroughly revised, updated Fourth edition. Over 70 leading experts provide comprehensive, current information on all infections--both neural-specific and systemic--that involve the central nervous system. Areas with significant new clinical information include treatment of tuberculosis, non-tubercular mycobacterial infections, brain abscess, and Lyme disease"--Provided by publisher.
  • Digital
    Anton G. Kutikhin, Arseniy E. Yuzhalin, Elena B. Brusina.
    Springer2013
    The Criteria of Inclusion of Infectious Agents in the List of Biological Carcinogens -- General Mechanisms of Biological Carcinogenesis -- The Role of Bacteria in Cancer Development -- The Role of Protozoa in Cancer Development -- The Role of Helminthes and Fungi in Cancer Development -- Organ Microbiota in Cancer Development: The Holy Grail of Biological Carcinogenesis -- Conclusions: Are We There Yet?
  • Digital
    edited by Carmen Buchrieser, Hubert Hilbi.
    Springer2013
    Identification of Legionella in the environment / Natalia A. Kozak, Claressa E. Lucas, and Jonas M. Winchell -- Identification of Legionella in clinical samples / Sophie Jarraud [and others] -- Sequence-based identification of Legionella / Rodney M. Ratcliff -- Investigation of outbreaks : epidemiology / Carol Joseph -- Outbreak investigations and identification of Legionella in contaminated water / Susanne Lee and John Lee -- Typing methods for Legionella / Christian Lück [and others] -- Culturing, media, and handling of Legionella / Christa H. Chatfield and Nicholas P. Cianciotto -- Intracellular metabolism of Legionella by isotopologue profiling / Klaus Heuner and Wolfgang Eisenreich -- Induction of competence for natural transformation in Legionella pneumophila and exploitation for mutant construction / Carmen Buchrieser and Xavier Charpentier -- Constructing unmarked gene deletions in Legionella pneumophila / Andrew Bryan, Zachary D. Abbott, and Michele S. Swanson -- Natural biofilm formation with Legionella pneumophila / Emilie Portier and Yann Hechard -- Production of L. pneumophila monospecies biofilms in a low-nutrient-concentration medium / Sophie Pécastaings and Christine Roques -- Enrichment of outer membrane vesicles shed by Legionella pneumophila / Jens Jäger and Michael Steinert -- Analysis of Legionella infection by flow cytometry / André N. Tiaden, Aline Kessler, and Hubert Hilbi -- Analysis of Legionella infection using RNAi in Drosophila cells / Dennise A. De Jesús, Tamara J. O'Connor, and Ralph R. Isberg -- Immunofluorescence imaging of Legionella infection in vitro / Stefan S. Weber and Annette Oxenius -- Electron microscopy of Legionella and Legionella-infected cells / Gary Faulkner and Rafael A. Garduño -- Pathogen vacuole purification from Legionella-infected amoeba and macrophages / Christine Hoffmann, Ivo Finsel, and Hubert Hilbi -- Methods for determining protein translocation by the Legionella pneumophila Dot/Icm type IV secretion system / Wenhan Zhu and Zhao-Qing Luo -- Subcellular localization of Legionella Dot/Icm effectors / Adam J. Vogrin [and others] -- Purification and characterization of Legionella U-box-type E3 ubiquitin ligase / Hiroki Nagai and Tomoko Kubori -- Legionella phospholipases implicated in infection : determination of enzymatic activities / Kathleen Seipel and Antje Flieger -- Interactions of Legionella effector proteins with host phosphoinositide lipids / Stephen Weber, Stephanie Dolinsky, and Hubert Hilbi -- Characterization of Legionella lipopolysaccharide / Christian Lück and Jürgen H. Helbig -- Tetrahymena and acanthamoeba model system / Sharon G. Berk and Rafael A. Garduño -- Dictyostelium host response to Legionella infection : strategies and assays / Salvatore Bozzaro, Barbara Peracino, and Ludwig Eichinger -- Caenorhabditis elegans model of Legionella infection / Ann Karen C. Brassinga and Costi D. Sifri -- Infection of nonphagocytic host cells by Legionella / Shandra R. Day, Costi D. Sifri, and Paul S. Hoffman -- Analyzing caspase-1 activation during Legionella pneumophila infection in macrophages / Christopher L. Case and Craig R. Roy -- Mouse as a model for pulmonary Legionella infection / Juliana I. Hori and Dario S. Zamboni -- Assessment of Legionella-specific immunity in mice / Stefan S. Weber, Nicole Joller, and Annette Oxenius -- Guinea pig model of legionnaires' disease / Paul H. Edelstein -- Human susceptibility to legionnaires' disease / William R. Berrington and Thomas R. Hawn -- cDNA library construction for next-generation sequencing to determine the transcriptional landscape of Legionella pneumophila / Tobias Sahr and Carmen Buchrieser -- Methods to study Legionella transcriptome in vitro and in vivo / Sebastien P. Faucher and Howard A. Shuman -- Co-immunoprecipitation : protein-RNA and protein-DNA interaction / Tobias Sahr and Carmen Buchrieser -- Identification of Legionella effectors using bioinformatic approaches / Gil Segal.
  • Digital
    Rinki Kapoor.
    The increasing prevalence of chronic, difficult-to-treat resistant bacterial infections have created a pressing need for the discovery of promising, novel pharmaceutical candidates that could replace or complement current therapies, which are becoming less reliable and effective due to a rise in bacterial resistance. Antimicrobial peptides (AMPs) are a naturally occurring, ubiquitous, and ancient class of antibiotics that offer a unique template for the development of novel antimicrobial therapies. However, in vivo therapeutic peptides have a short half-life since they are easily degraded by proteases, thus reducing their bioavailability, which renders them a less attractive choice therapeutically. Consequently, non-natural mimics of AMPs, which can emulate the favorable characteristics of AMPs are becoming significantly important. Poly-N-substituted glycines, also called "Peptoids", are structural and functional mimics of AMPs and are resistant to proteolysis. Predecessors in the Barron laboratory designed and characterized antimicrobial peptoids against free-floating, planktonic bacteria. However, almost 60% of infections are caused by bacterial biofilms. These complex communities of microorganisms are protected by an excreted matrix of adhesive biomacromolecules and are more difficult to kill with conventional antibiotics than planktonic bacteria. Furthermore, to develop peptoids as potential therapeutics, the mechanisms by which they interact with bacteria need to be understood, which are still under investigation. Here, we report that peptoids have similar or better efficacy than conventional antibiotics against biofilms of a clinical isolate of drug-resistant P. aeruginosa. We determined the effects of peptoids on bacterial biomass and cell viability, by Crystal Violet assay and bacterial plating, respectively. We also explored the efficacy of peptoids against Mycobacterium (an organism resistant to antibiotics due to the presence of a thick waxy coating) and intracellular L. monocytogenes by bioluminescent imaging. In addition, we also investigated the mechanisms of action of peptoids and peptides by biophysical techniques (Ultra-Violet Visible spectroscopy) and bioluminescent imaging. We report that peptoids are non-lytic and cause bacterial killing by aggregating the bacterial ribosomes and decreasing ATP levels inside the cell. Lastly, we present a mouse wound model, which suggests that peptoids are effective in vivo in reducing P. aeruginosa infections.
  • Print
    David W. Hecht, Diane M. Citron, Joanne Dzink-Fox, William W. Gregory, Nilda V. Jacobs, Stephen G. Jenkins, Jon E. Rosenblatt, Audrey N. Schuetz, Hannah Wexler.
    Status: Not Checked Out
  • Digital
    edited by José-Luis Barredo.
    Springer2012
    Pathways of carotenoid biosynthesis in bacteria and microalgae / J. Paniagua-Michel, Jorge Olmos-Soto, and Manuel Acosta Ruiz -- Selection and taxonomic identification of carotenoid-producing marine actinomycetes / Francisco Romero -- Isolation, characterization, and diversity of novel radiotolerant carotenoid-producing bacteria / Dalal Asker [and others] -- Novel radio-tolerant astaxanthin-producing bacterium reveals a new astaxanthin derivative : astaxanthin dirhamnoside / Dalal Asker [and others] -- Novel zeaxanthin-producing bacteria isolated from a radioactive hot spring water / Dalal Asker [and others] -- Novel approach in the biosynthesis of functional carotenoids in Escherichia coli / Hisashi Harada and Norihiko Misawa -- Engineering Escherichia coli for canthaxanthin and ataxanthin biosynthesis / Qiong Cheng and Luan Tao -- Analysis of canthaxanthin production by Gordonia jacobaea / Patricia Veiga-Crespo [and others] -- Isolation and light-stimulated expression of canthaxanthin and spirilloxanthin biosynthesis genes from the photosynthetic bacterium Bradyrhizobium sp. Strain ORS278 / Eric Giraud and Andre Vermeglio -- Construction of carotenoid biosynthetic pathways through chromosomal integration in methane-utilizing bacterium Methylomonas sp. strain 16a / Rick W. Ye and Kristen Kelly -- Genetic modification in Bacillus subtilis for production of C30 carotenoids / Isamu Maeda -- Carotenoids' production from halophilic bacteria / Maria de Lourdes Moreno [and others] -- Construction and utilization of carotenoid reporter systems : identification of chromosomal integration sites that support suitable expression of biosynthetic genes and pathways / Pamela L. Sharpe and Deana J. DiCosimo -- Directed evolution of carotenoid synthases for the production of unnatural carotenoids / Maiko Furubayashi and Daisuke Umeno -- High-Throughput Screen for the Identi fi cation of improved catalytic activity: b-carotene hydroxylase / Mark A. Scaife [and others] -- DNA fingerprinting intron-sizing method to accomplish a specific, rapid, and sensitive identification of carotenogenic Dunaliella species / Jorge Olmos-Soto [and others] -- Ketocarotenoid biosynthesis in transgenic microalgae expressing a foreign beta-C-4-carotene oxygenase gene / Marta Vila [and others] -- Characterization of carotenogenesis genes in the cyanobacterium Anabaena sp. PCC 7120 / Hajime Masukawa, Mari Mochimaru, and Shinichi Takaichi -- Obtaining lutein-rich extract from microalgal biomass at preparative scale / Jose M. Fernandez-Sevilla, F. Gabriel Acien Fernandez, and Emilio Molina Grima -- NMR-based isotopologue profiling of microbial carotenoids / Eva Eylert, Adelbert Bacher, and Wolfgang Eisenreich -- Analysis of diapocarotenoids found in pigmented Bacillus species / Laura Perez-Fons and Paul D. Fraser.
  • Digital/Print
    editor, Mark Lyte.
    Digital : Springer2016
    Print2016
    Microbial Endocrinology: An Ongoing Personal Journey -- New Trends and Perspectives in Evolutionary Considerations of Neurotransmitters in Microbial, Plant and Animal Cells -- Catecholamine-directed Epithelial Cell Interactions With Bacteria in the Intestinal Mucosa -- Modulation of the Interaction of Enteric Bacteria with Intestinal Mucosa -- Dietary Catechols and their Relationship to Microbial Endocrinology -- Mechanisms by Which Catecholamines Induce Growth in Gram-Negative and Gram-Positive Human Pathogens -- Molecular Profiling: Catecholamine Modulation of Gene Expression in Escherichia coli O157:H7 and Salmonella enterica serovar Typhimurium -- Microbial Endocrinology of Pseudomonas aeruginosa -- Interkingdom Chemical Signaling in Enterohemorrhagic Escherichia coli O157:H7 -- Role of Microbial Endocrinology in Periodontal Disease -- Staphylococci, Catecholamine Inotropes and Hospital-Acquired Infections -- Experimental Design Considerations for In Vitro Microbial -- The Role of the Microbiome in the Relationship of Asthma and Affective Disorders -- Psychological Stress, Immunity and Effects on Indigenous Flora -- Microbiome to Brain: Unraveling the Multidirectional Axes of Communication -- Mycologic Endocrinology.
  • Digital/Print
    Mark Lyte, John F. Cryan, editors.
    Digital : Springer2014
    Print2014
    "The field of microbial endocrinology is expressly devoted to understanding the mechanisms by which the microbiota (bacteria within the microbiome) interact with the host ("us"). This interaction is a two-way street and the driving force that governs these interactions are the neuroendocrine products of both the host and the microbiota. Chapters include neuroendocrine hormone-induced changes in gene expression and microbial endocrinology and probiotics. This is the first in a series of books dedicated to understanding how bi-directional communication between host and bacteria represents the cutting edge of translational medical research, and hopefully identifies new ways to understand the mechanisms that determine health and disease"--Publisher's description.
  • Digital
    volume editors, Hilde de Reuse, Stefan Bereswill.
    Karger2009.
    Genome comparison of bacterial pathogens / Wassenaar, T.M. ... [et al.] -- In silico reconstruction of the metabolic and pathogenic potential of bacterial genomes using subsystems / McNeil, L.K., Aziz, R.K. -- The bacterial pan-genome and reverse vaccinology / Tettelin, H. -- 'Guilty by association' : protein-protein interactions (PPIS) in bacterial pathogens / Schauer, K., Stingl, K -- Helicobacter pylori sequences reflect past human migrations / Moodley, Y., Linz, B. -- Helicobacter pylori genome plasticity / Baltrus, D.A., Blaser, M.A., Guillemin, K. -- Genomics of Thermophilic campylobacter species / Gaskin, D.J.H. ... [et al.] -- Adaptation of pathogenic E. coli to various niches : genome flexibility is the key / Brzuszkiewicz, E. ... [et al.] -- Role of horizontal gene transfer in the evolution of Pseudomonas aeruginosa virulence / Qiu, X., Kulasekara, B.R., Lory, S. -- The genus Burkholderia : analysis of 56 genomic sequences / Ussery, D.W. ... [et al.] -- Genomics of host-restricted pathogens of the genus Bartonella / Engel, P., Dehio, C. -- Legionella pneumophila - host interactions : insights gained from comparative genomics and cell biology / Lomma, M. ... [et al.] -- A proteomics view of virulence factors of Staphylococcus aureus / Engelmann, S., Hecker, M. -- Pathogenomics of mycobacteria / Gutierrez, M.C., Supply, P., Brosch, R.
  • Digital
    Christiane Dahl, Cornelius G. Friedrich (editors).
    Springer2008
    Genetics and genomics of sulfate respiration in desulfovibrio / Judy D. Wall ... [et al.] -- Living on sulfate : three-dimensional structure and spectroscopy of adenosine 5'-phosphosulfate reductase and dissimilatory sulfite reductase / Günter Fritz ... [et al.] -- Respiratory membrane complexes of Desulfovibrio / Inês A. Cardoso Pereira -- Biochemical and evolutionary aspects of eukaryotes that inhabit sulfidic environments / Ursula Theissen, William Martin -- Evolution and ecology of microbes dissimilating sulfur compounds : insights from siroheme sulfite reductases / Alexander Loy, Stephan Duller, Michael Wagner -- Genomic and evolutionary perspectives on sulfur metabolism in green sulfur bacteria / Niels-Ulrik Frigaard, Donald A. Bryant -- Differential-expression proteomics for the study of sulfur metabolism in the chemolithoautotrophic Acidithiobacillus ferrooxidans / Lissette Valenzuela ... [et al.] -- Sulfur and light? History and "thiology" of the phototrophic sulfur bacteria / Hans G. Trüper -- Thiosulfate and sulfur oxidation in purple sulfur bacteria / Frauke Grimm, Bettina Franz, Christiane Dahl -- Sulfur oxidation in Chlorobium tepidum (syn. Chlorobaculum tepidum) : genetic and proteomic analyses / Leong-Keat Chan, Rachael Morgan-Kiss, Thomas E. Hanson -- Structural insights into component SoxY of the thiosulfate-oxidizing multienzyme system of Chlorobaculum thiosulfatiphilum / Jan Stout ... [et al.] -- Redox control of chemotrophic sulfur oxidation of Paracoccus pantotrophus / Cornelius G. Friedrich ... [et al.] -- Bacterial sulfite-oxidizing enzymes : enzymes for chemolithotrophs only? / Ulrike Kappler -- Sulfonates and organotrophic sulfite metabolism / Alasdair M. Cook, Theo H.M. Smits, Karin Denger -- Oxidation of sulfur and inorganic sulfur compounds in Acidianus ambivalens / Arnulf Kletzin -- A novel coenzyme F420 dependent sulfite reductase and a small sulfite reductase in methanogenic archaea / Eric F. Johnson, Biswarup Mukhopadhyay -- Archaeal and bacterial sulfur oxygenase-reductases : genetic diversity and physiological function / Shuang-Jiang Liu -- Diversity of halophilic sulfur-oxidizing bacteria in hypersaline habitats / Dimitry Y. Sorokin -- Sulfur oxidation at deep-sea hydrothermal vents / Stefan M. Sievert ... [et al.] -- Speciation analysis of microbiologically produced sulfur by X-ray absorption near edge structure spectroscopy / Alexander Prange -- Controls on isotope fractionation during dissimilatory sulfate reduction / Joost Hoek, Donald E. Canfield -- Bioprocess engineering of sulfate reduction for environmental technology / Piet N.L. Lens ...[et al.] -- Impact of nitrate on the sulfur cycle in oil fields / Gerrit Voordouw.
  • Digital
    edited by Otto Holst.
    Springer2011
    Part I: Bacterial protein toxins -- Detection of bacterial protein toxins by solid phase magnetic immunocapture and mass spectrometry / Gabriella Pocsfalvi and Gitta Schlosser -- Sensitive and rapid detection of cholera toxin-producing Vibrio cholerae using loop-mediated isothermal amplification / Wataru Yamazaki -- Ultrasensitive detection of botulinum neurotoxins and anthrax lethal factor in biological samples by ALISSA / Karine Bagramyan and Markus Kalkum -- Examination of Bacillus anthracis spores by multiparameter flow cytometry / William C. Schumacher [and others] -- A cell-based fluorescent assay to detect the activity of shiga toxin and other toxins that inhibit protein synthesis / Shane Massey, Beatriz Quiñones, and Ken Teter -- Use of a vero cell-based fluorescent assay to assess relative toxicities of shiga toxin 2 subtypes from Escherichia coli / Beatriz Quiñones and Michelle S. Swimley -- Molecular methods: chip assay and quantitative real-time PCR: in detecting hepatotoxic cyanobacteria / Anne Rantala-Ylinen, Hanna Sipari, and Kaarina Sivonen -- Part II: Endotoxins -- Capillary electrophoresis chips for fingerprinting endotoxin chemotypes from whole-cell lysates / Béla Kocsis [and others] -- Isolation of smooth-type lipopolysaccharides to electrophoretic homogeneity / Elder Pupo -- A method for unobtrusive labeling of lipopolysaccharides with quantum dots / Carlos Morales-Betanzos, Maria Gonzalez-Moa, and Sergei A. Svarovsky -- Fluorescence-based methods to assay inhibitors of lipopolysaccharide synthesis / Marcy Hernick -- Micromethods for lipid a isolation and structural characterization / Martine Caroff and Alexey Novikov -- Two efficient methods for the conjugation of smooth-form lipopolysaccharides with probes bearing hydrazine or amino groups. I. LPS activation with cyanogen bromide / Fernando Battaglini and Diego Pallarola -- Two efficient methods for the conjugation of smooth-form lipopolysaccharides with probes bearing hydrazine or amino groups. II. LPS activation with a cyanopyridinium agent / Fernando Battaglini and Diego Pallarola -- Part III: Mold fungus toxins -- Extraction and analysis of fumonisins and compounds indicative of fumonisin exposure in plant and mammalian tissues and cultured cells / Nicholas C. Zitomer and Ronald T. Riley -- Determination of fumonisins B₁ and B₂ in maize food products by a new analytical method based on high-performance liquid chromatography and fluorimetric detection with post-column derivatization / Marilena Muscarella [and others] -- A confirmatory method for aflatoxin M₁ determination in milk based on immunoaffinity cleanup and high-performance liquid chromatography with fluorometric detection / Marilena Muscarella [and others] -- Simultaneous determination of aflatoxins B₁, B₂, G₁, and G₂ in foods and feed materials / Marilena Muscarella [and others] -- Highly sensitive PCR-based detection specific to Aspergillus flavus / Amaia González-Salgado -- A rapid enzymatic method for aflatoxin B detection / Danila Moscone, Fabiana Arduini, and Aziz Amine.
  • Digital
    Maurice B. Hallett editor.
    Springer2020
    Intro -- Preface -- Contents -- Contributors -- 1 An Introduction to Phagocytosis -- Introduction to Phagocytosis -- The Cell Biology of Phagocytosis -- Phagocytosis Dissected -- The Importance of Phagocytosis -- Evolution and Phagocytosis -- Introduction to the Chapters in This Book -- 2 A Brief History of Phagocytosis -- Introduction -- Purpose of Chapter -- Let's Start at the Very Beginning -- The Eureka Moment of Metchnikoff -- Inside the Phagocyte -- Phagosomal pH -- Ca2+ Ions and Phagocytosis -- Conclusion -- 3 The Role of Membrane Surface Charge in Phagocytosis -- Introduction Lipids That Contribute to Phagocytosis and Phagosome Maturation -- Phospholipid Dynamics and Inner Leaflet Charge During Phagocytosis and Phagosome Maturation -- Role of Electrostatic Interactions in Protein Localization During Phagocytosis and Phagosome Maturation -- Relevance of Inner Leaflet Surface Charge to Phagocytes and Immunity -- Concluding Remarks -- 4 Receptor Models of Phagocytosis: The Effect of Target Shape -- Introduction -- Why Modelling? -- Receptor Models of Phagocytosis -- The Basic Receptor Model -- Phagocytosis Versus Other Types of Endocytosis -- The Effect of Target Shape Known Experimental Results -- Modelling Shape Dependence -- Model Extensions and the Future -- Summary -- 5 Decision Making in Phagocytosis -- Introduction -- Uptake, Processing, and Release of Long Particles -- Uptake of a Long Particle -- Phagosome Processing -- Release of a Particle -- Myosin-II Does Not Accumulate on the Incipient Phagosome -- Conversion of a Tubular Phagosome into a Bleb -- Simultaneous Uptake and Release of Particles -- Struggle for a Bacterium -- Discussion -- 6 Membrane Tension and the Role of Ezrin During Phagocytosis -- Introduction Apparent Expansion of Cell Surface Area During Phagocytosis -- Exocytotic Addition to the Plasma Membrane -- Cell Surface "Wrinkles" -- Membrane Tension and Cell Shape Changes -- Wrinkles and Membrane Tension -- Molecular Maintenance of Membrane Tension -- Ezrin -- Ezrin and Membrane Tension -- Ezrin and Phagocytosis -- Regulation Membrane Tension by Ezrin During Phagocytosis -- Actin Push and the Brownian Ratchet -- Conclusion and Synthesis -- 7 Molecular Mechanisms of Calcium Signaling During Phagocytosis -- Abbreviations -- Introduction -- Overview of Ca2+ Signaling -- Phagocytic Ca2+ Signals Ca2+-Permeable Channels Involved in Phagocytic Ca2+ Signals -- ORAI Channels, STIM Proteins and Junctate -- TRPC Channels -- TRPC3 -- TRPC4/5 -- TRPC6 -- TRPM Channels -- TRPM2 -- TRPM8 -- TRPML Channels -- TRPV Channels -- TRPV1 and TRPV2 -- TRPV4 -- P2X Channels -- P2X7 -- P2X4 -- Conclusions and Future Directions -- 8 Calpain Activation by Ca2+ and Its Role in Phagocytosis -- Introduction -- Ca2+ in Phagocytosis and Cell Shape Change -- Calpain Activation in Shape Change -- Calpain in Phagocytosis -- Structure of Calpain 1 and 2 -- Physiological Activation of Calpain by Ca2+ in Cells Conclusions
  • Digital
    Carmen Dolores Cordova.
    The gamma-proteobacterium Shewanella oneidensis MR-1 utilizes a complex electron transfer network composed primarily of c-type cytochromes as well as iron-sulfur proteins, molybdoenzymes, and flavins, to respire under anoxic conditions a variety of compounds, including fumarate, nitrate, and dimethylsulfoxide (DMSO) in addition to Fe (III) and Mn (IV) minerals. Central to several respiratory pathways in this dissimilatory metal reducing bacterium (DMRB), including the electron transfer pathway to Fe (III), is CymA, a cytoplasmic membrane-bound tetraheme c-type cytochrome that functions as the major hydroquinone dehydrogenase and couples electron transport to various periplasmic oxidoreductases. Using a genetic approach involving the reconstruction of the putative electron transport chain of dissimilatory iron reduction from Shewanella oneidensis MR-1 in Escherichia coli, I showed that expression of cymA was necessary and sufficient to convert E. coli into a dissimilatory iron reducing (DIR) bacterium, indicating that CymA as a terminal reductase was the minimal electron transport chain within S. oneidensis MR-1 to Fe (III). In addition, we isolated and characterized a [delta]cymA suppressor mutant that was capable of respiration of fumarate, ferric citrate, and DMSO, but not of nitrate. The suppression was found to be due to insertion sequence-mediated transcriptional activation of mccCD, which encode for a putative periplasmic iron sulfur protein and an integral membrane hydroquinone dehydrogenase, respectively.
  • Print
    Richard H. ffrench-Constant, editor.
    This book provides an essential update on the startling array of novel insecticidal toxins and drugs produced by the fascinating bacterium Photorhabdus. The respective chapters describe everything from the detailed molecular biology of the 'Toxin complexes' or Tc's to the complexity of insect immune response in relation to both the bacterium and its nematode vector. The volume covers both primary (toxin production and regulation) and secondary (natural product synthesis and regulation) metabolism and emphasises the potential use of toxins and drugs in both agriculture and medicine. It also discusses in detail two totally novel quorum sensing mechanisms and the likely role of LuxR solos in sensing the presence of different bacterial hosts. Lastly, the book explores the unique case of P. asymbiotica, which seems to have evolved the ability to infect both insects and humans. This synthesis proves that Photorhabdus truly does offer a 'gold mine' for the discovery of novel insecticidal proteins and novel natural products with potential uses in agriculture and medicine alike.

Access restricted to Stanford community

Shortcut to Licensed Content

Lane Gateway to Licensed Content

TO INSTALL, DRAG THIS BUTTON to your browser Bookmarks or Tools Bar.

What is it?

Lane Gateway to Licensed Content

Bookmark on Other Websites

Bookmark on Lane

  • TO INSTALL, RIGHT CLICK this button.
  • Select "Add to Favorites" (click “Continue” if you see a security alert)
  • From the "Create in" menu, select “Favorites Bar” (IE8, IE9) to install
  • Once installed it will look like this
  • Click "Bookmark on Lane" to bookmark any webpage
  • Your saved bookmark will appear on this page
TO INSTALL, RIGHT CLICK this button.

What is it?

Derived from Current Medical Diagnosis & Treatment, AccessMedicine's Quick Medical Diagnosis & Treatment provides topic reviews with key diagnostic and treatment features for more than 500 diseases.

A repository of medical knowledge from internal medicine, cardiology, genetics, pharmacy, diagnosis and management, basic sciences, patient care, and more.

Continuously expanding, all databases in the repository contain the latest editions of selected medical titles.

MicroMedex: Premier pharmaceutical information source containing multiple databases and drug reference tools. Of particular value is DRUGDEX Evaluations, one of the most comprehensive drug sources available.DynaMed Plus is a clinical information resource used to answer questions quickly at the point-of-care. Easy-to-interpret Levels of Evidence help clinicians rapidly determine the quality of the available evidence.

Biomedical and pharmacological abstracting and indexing database of published literature, by Elsevier. Embase® contains over 32 million records from over 8,500 currently published journals (1947-present) and is noteworthy for its extensive coverage of the international pharmaceutical and alternative/complementary medicine literature.

Scopus is the largest abstract and citation database of peer-reviewed literature: scientific journals, books and conference proceedings.A drug information resource containing: American Hospital Formulary System (AHFS), drug formulary for Lucile Packard Children's Hospital (LPCH) and Stanford Hospital & Clinics (SHC), Lexi-Drugs (adverse reactions, dosage and administration, mechanism of action, storage, use, and administration information), Lexi-Calc, Lexi-ID, Lexi-I.V. Compatibility (King Guide), Lexi-Interact, and Lexi-PALS.Cumulative Index to Nursing and Allied Health Literature (CINAHL) contains coverage of nursing and allied health literature.A knowledge database that provides access to topic reviews based on over 6000 clinically relevant articles. The evidence-based content, updated regularly, provides the latest practice guidelines in 59 medical specialties.Provides critical assessments of systematic reviews compiled from a variety of medical journals.Selects from the biomedical literature original studies and systematic reviews that are immediately clinically relevant and then summarizes these articles in an enhanced abstract with expert commentary.

Multidisciplinary coverage of over 10,000 high-impact journals in the sciences, social sciences, and arts and humanities, as well as international proceedings coverage for over 120,000 conferences.

Includes cited reference searching, citation maps, and an analyze tool.

Features systematic reviews that summarize the effects of interventions and makes a determination whether the intervention is efficacious or not.

Cochrane reviews are created through a strict process of compiling and analyzing data from multiple randomized control trials to ensure comprehensiveness and reliability.

Provides systematic coverage of the psychological literature from the 1800s to the present through articles, book chapters and dissertations.BMJ Clinical Evidence. A clinical information tool built around systematic reviews summarizing the current state of knowledge about prevention and treatment of clinical conditions.PIER (Physicians' Information and Education Resource) is a Web-based decision-support tool designed for rapid point-of-care delivery of up-to-date, evidence-based guidance for primary care physicians.Cochrane Central Register of Controlled Trials (CENTRAL) provides access to 300,000 controlled trials that have been identified the Cochrane Collaboration.Provides drug information targeted for patients.A continually updating drug monograph.ECRI Guidelines Trust: A comprehensive database of evidence-based clinical practice guidelines and related documents.MedlinePlus: A repository of health information from the National Library of Medicine. Links are from trusted sites. No advertising, no endorsement of commercial companies or productsLPCH CareNotes via MicroMedex: Patient education handouts customized by LPCH clinical staffMicromedex Lab Advisor: Evidence based laboratory test informationA drug database organized by generic name, trade name and drug class.LPCH / Stanford Hospital Formulary.A goldmine of trusted consumer health information from the world's largest medical library.A trusted source of expert advice for and about kids, providing the information necessary to help patients and parents understand their unique needs.Provides patient handouts from the American Academy of Family Physician.Access to the Stanford Health Library for patients.Lane provides access to over 5,000 eBooks many of which provide helpful background material that will prepare you to better tackle primary literature.

Largest, broadest eBook package; covers all sciences, as well as technology (including software), medicine, and humanities.

In addition to covering Wiley and Springer, MyiLibrary is also the only provider for Oxford and Cambridge University Press titles. No seat restrictions.

A collection of biomedical books that can be searched directly by concept, and linked to terms in PubMed abstracts.

A web-based, decision support system for infectious diseases, epidemiology, microbiology and antimicrobial chemotherapy. The database, updated weekly, currently includes 337 diseases, 224 countries, 1,147 microbial taxa and 306 antibacterial (-fungal, -parasitic, -viral) agents and vaccines.

Over 10,000 notes outline the status of specific infections within each country.

Large number of high quality software and database programming titles from O'Reilly. Other software titles are also available from Sams and Prentice Hall. Limited to 7 concurrent users.Vast collection of software and database programming titles from multiple publishers, including Microsoft Press.Largest provider of engineering-related eBooks; includes titles in computer science and biomedical engineering.Over 4,000 full-text e-books covering scientific and technical information from CRC Press and others. Many handbooks and single volume reference sources.Includes peer-reviewed life science and biomedical research protocols compiled from Methods in Molecular Biology, Methods in Molecular Medicine, Methods in Biotechnology, Methods in Pharmacology and Toxicology, Neuromethods, the Biomethods Handbook, the Proteomics Handbook, and Springer Laboratory Manuals.Contains full text access to selected biomedical and nursing books.

Provides online, full-text access to Springer's journal titles as well as journals from other publishers.

Subjects include: life sciences, chemical sciences, environmental sciences, geosciences, computer science, mathematics, medicine, physics and astronomy, engineering and economics. Also includes eBooks.

Collection of over 8 thousand fulltext titles in engineering, math, and basic and applied biomedical research. Coverage is from 1967 to the present.A library of ebooks on a wide array of topics, digitized and made available online in conjunction with the original publishers.