Books

Contents:
V. 1
Sect. 1: Thoracic surgery
Pt. A: Evaluation and care
Pt. B: Endoscopy
Pt. C: Trauma
Pt. D: Trachea
Pt. E: Benign lung disease
Pt. F: Lung cancer
Pt. G: Other lung malignancy
Pt. H: Chest wall
Pt. I: Pleura
Pt. J: Diaphragm
Pt. K: Esophagus-Benign disease
Pt. L: Esophagus-cancer
Pt. M: Mediastinum
Pt. N: The future
Sect. 2: Adult cardiac surgery
Pt. A: Basic science
Pt. B: Diagnostic procedures
Pt. C: Medical- and catheter-based treatment of cardiovascular disease
Pt. D: Perioperative and intraoperative care of the cardiac surgical patient
V. 2
Pt. E: Surgical management of aortic disease
Pt. F: Surgical management of valvular heart disease
Pt. G: Management of cardiac arrhythmias
Pt. H: Surgical management of coronary artery disease and its complications
Pt. I: Surgical management of heart failure
Sect. 3: Congenital heart surgery.

Summary: "The only text to cover the full range of adult cardiac, thoracic, and pediatric chest surgery, Sabiston and Spencer Surgery of the Chest provides unparalleled guidance in a single, two-volume resource. This gold standard reference, edited by Drs. Frank Sellke, Pedro del Nido, and Scott Swanson, covers today's most important knowledge and techniques in cardiac and thoracic surgery--the information you need for specialty board review and for day-to-day surgical practice. Meticulously organized so that you can quickly find expert information on open and endoscopic surgical techniques, this 10th Edition is an essential resource not only for all cardiothoracic surgeons, but also for physicians, residents, and students concerned with diseases of the chest"-- publisher's description.

Contents:
Thoracic Surgery
Adult Cardiac Surgery
Congenital Heart Surgery.

Summary: "Sacroiliac joint pain is one of the most common painful conditions, as disorders of this joint are often the cause or a contributing factor to back pain. Treatment of sacroiliac joint pain has advanced significantly in the last decade, ranging from minor interventions to major surgical interventions. Written for pain physicians, neurologists, neurosurgeons, and orthopedic surgeons at all levels of training and practice, this book highlights new and innovative approaches to sacroiliac disease so clinicians may incorporate current techniques into practice. The international roster of authors present up to date information on interventional and surgical pain procedures including peripheral nerve stimulation, surgical fusion, and regenerative techniques. In addition to providing well-illustrated, step-by-step guidance on procedural technique, chapters review patient selection, instrumentation, complications management, and outcomes."--Provided by publisher.

Contents:
Anatomy of the Sacroiliac Joint / John Zaky, Christopher Haddad, and Sherif Zaky
Surgical Instruments / Ali Arastu and Tariq Malik
Sacroiliac Joint Injection Techniques / Ali Arastu and Tariq Malik
Sacral Lateral Branch Nerve Block / Evan Parker, Christine Zaky, and George Girgis
Sacroiliac Joint Radiofrequency Ablation / Timothy J. Woodin, Nasir Hussain, and Alaa Abd-Elsayed
Peripheral Nerve Stimulation of the Sacroiliac Joint / Ryan Budwany, Alaa Abd-Elsayed, and Yeshvant Navalgund
Sacroiliac Joint Posterior Fusion / Alaa Abd-Elsayed and Ahish Chitneni
Lateral Sacroiliac Joint Fusion / Hamid R. Abbasi, Alaa Abd-Elsayed, and Nicholas R. Storlie
Measuring Outcomes of Improvement / Meera Kirpekar, Emmanuel Faluade, and Divya Patel

Contents:
Prerequisits
Living safely and actively in and around the home Four applied examples from avatars and ambient cubes to active walkers
Using gaze control for communication and environment control How to find a good position and start working
Caring TV
for older people with multimorbidity living alone Positive feedback from users in Berlin and rural Mecklenburg-West Pomerania
Arm rehabilitation at home for people with stroke: staying safe Encouraging results from the co-designed LifeCIT pro-gramme
Telemonitoring in home care Creating the potential for a safer life at home
Empowering the elderly and promoting active ageing through the Internet The benefit of e-inclusion programmes
Use and development of new technologies in public wel-fare services A user-centred approach using step by step communication for problem solving
Parents' experiences of caring for a ventilator-dependent child: a review of the literature
Evaluation and outcomes of assistive technologies in an outpatient setting
a technical-nursing science approach
Assistive technology for people with dementia: ethical considerations.

Summary: Filler injection is one of the most common aesthetic procedure. There are a lot of guidelines but there are no illustrated step by step instructions on safe filler injection procedures. The book will offer guidance to clinicians who wish to expand their practice to minimally invasive cosmetic procedures. Injection techniques for hyaluronic acid filler is highlighted to help practitioners perform the procedures more effectively and safely with evidence based approach. The most safe procedure including vascular anatomical illustration and ultrasound findings, rheological data is presented.

Contents:
1. Prevention of filler complication
2. Property of HA filler
3. Forehead augmentation
4. Glabellar wrinkle correction
5. Temple augmentation
6. Nose augmentation
7. Midface augementation
8. Nasolabial fold correction
9. Low face correction.

Summary: "The fourth edition of Safe Handling of Hazardous Drugs provides nurses with the latest details and procedures needed to keep safe in the workplace"-- Provided by publisher.

Summary: Safety is a paramount factor in orthopaedics, whether the patient is being treated conservatively or surgically. Although vast advances have been made in the instruments, implants, and techniques of orthopaedic surgery, considerable complications continue to occur. Iatrogenic injuries during surgery can cause significant morbidity and even mortality. To avoid neurovascular and other serious complications, the orthopaedic surgeon must have both a deep understanding of anatomy that can be drawn on in the operating room and exceptional technical skills. The goal of treatment of limb fractures is to restore limb length and anatomic articular surface alignment and rotation, as well as to create adequate fixation for early mobilization of the associated joint with minimal complications. Safe Orthopaedic Surgery includes facts about applied anatomy and surgical techniques aimed at preventing neurovascular complications in various approaches to the specific bones and joints, including the clavicle, shoulder, humerus, elbow, forearm, wrist and hand, spine, hip, femur, knee, leg, and ankle and foot. Both conventional and minimally invasive techniques are considered. The prevention of surgical site infections and current thinking on antibiotic therapy in orthopaedic surgery are also covered. Organized into 13 chapters with a standard format, up-to-date references, and to-the-point, bulleted presentation for easy review, Safe Orthopaedic Surgery offers vital information on performing operations safely and precisely--the safety principles that are invaluable to every orthopaedic surgeon.

Contents:
Preventing Surgical Site Infection and Safe Usage of Antibiotics and in Orthopaedic Surgery
Safe Clavicle Fracture Surgery
Safe Shoulder Surgery
Safe Humerus
Surgery
Safe Elbow Surgery
Safe Forearm Surgery
Safe Wrist & Hand Surgery
Safe Spine Surgery
Safe Hip Surgery
Safe Femur Surgery
Safe Knee Surgery.-Safe Leg Surgery
Safe Foot & Ankle Surgery.

Summary: "Safe Passage: A Guide to Addressing School Violence provides a road map for understanding and addressing violence of all kinds in the school environment. The editors emphasize that mass casualty events are but one species of violence, and that in fact school violence comes in many different forms, from bullying on campus to trauma off campus, from community gangs to violent crimes. Case vignettes illustrate and illuminate the range of violent situations likely to be encountered, as well as the advantages and disadvantages inherent in various interventions. The authors stress that threat assessment must take individual, school, and community variables into account. Safe Passage: A Guide to Addressing School Violence introduces readers to important concepts pertaining to school violence and serves as a practical guide for mitigating and preventing violence in our schools"-- Provided by publisher.

Contents:
Cover; Half Title; Title Page; Copyright; Dedication; Contents; Contributors; Foreword; Preface; Acknowledgments; PART I Foundations; 1 An Introduction to School Violence; 2 A Recipe for Violence: Immaturity, Impulsivity, and Aggression; 3 Inconvenient Truths: Profiling and Its Limitations; 4 Danger at Home: Addressing Violence Outside School; 5 Bullying and Cyberbullying; 6 Understanding and Addressing Youth Sexual Violence; 7 Growing Up in Fear: School Shootings, Attacks, and Gang Violence; PART II Threat and Risk Assessment; 8 Hostile Intent: The Principles of Threat Assessment 9 Avoiding Danger: The Principles of Violence Risk AssessmentPART III Interventions; 10 A System of Care: Addressing Aggression and Violence in Schools; 11 Assessing and Addressing School Climate; 12 Violence and the Media; Afterword; Appendix A: Example Threat Assessment Questions for Use With Grade School Students; Appendix B: Example Threat Assessment Questions for Use With Middle School Students; Appendix C: Example Threat Assessment Questions for Use With High School and College Students; Index; Back Cover

Summary: In medical practice, unfamiliarity with procedures increases the likelihood of occupational exposures. Learning to perform a procedure properly early on reinforces safe habits, improves overall surgical safety, and reduces occupational exposures. Safety in Office-Based Dermatologic Surgery is relevant to any healthcare professional who participates in office-based procedures, such as injections, biopsies, excisions, and laser surgery. The authors bring over 15 years? combined experience in training residents and medical students, enabling them to identify common unsafe practices in office-based surgery. Chapters are divided into individual procedures for easy referencing by students, trainees, as well as seasoned practitioners. Figures illustrate how seemingly innocuous actions and procedures can result in dangerous exposures to healthcare workers. Hazardous scenarios are subsequently followed with one or a series of safer solutions, with the accident and solution concisely explained and clearly illustrated.

Contents:
Epidemiology
What to do if exposed
Personal safety equipment
General Principles
Setting up a tray
Injection
Working with an assistant
Excision
Hemostasis
Suturing
Venipuncture
Curettage
Cryotherapy
Acne surgery
Nail clipping
Lasers and PDT.

Contents:
1: Approved Biologics Used For Therapy and their Adverse Effects
2: Monoclonal Antibodies: Introduction
3: Monoclonal Antibodies Approved for Cancer Therapy
4: Other Approved Therapeutic Monoclonal Antibodies
5: Cytokines
6: Fusion Proteins
7: Peptide Hormones
8: Glycoprotein Hormones
9: Enzymes Approved for Therapy
10: Blood Coagulation
11: Vaccines
12: Botulinum Neurotoxins
13: Biosimilars.

Contents:
Chapter 1. First Do No Harm: An overview of HIT and Patient Safety
Chapter 2. An overview of HIT-related errors
Section I. Errors Related to Various Types of Health Information Technologies
Chapter 3. Errors related to CPOE
Chapter 4. Errors related to alert fatigue
Chapter 5. Unintended consequences of bar-code assisted medication administration
Chapter 6. Errors related to outpatient e-prescribing
Chapter 7. Errors related to alarms and monitors
Chapter 8. Errors related to personal mobile technology
Section II. Health Information Technology Implementation Issues
Chapter 9. Improving clinical documentation integrity
Chapter 10. EHR and physician-patient communication
Chapter 11. Patient identification errors and HIT: Friend or foe?
Chapter 12. Errors related to health information exchange
Section III. Specialty Considerations
Chapter 13. Safety considerations in radiation therapy
Chapter 14. Safety considerations in pediatric informatics
Chapter 15.Safety considerations in ambulatory care informatics
Section IV. Organizational Considerations
Chapter 16. Health information technology and medical liability risks
Chapter 17. Improving safety through enterprise risk management
Chapter 18. Managing HIT contract process for patient safety
Chapter 19. Improving safety of medical device use through training.

Summary: "The substantially updated and revised Fifth Edition of this landmark handbook presents the state-of-the-art theory and practice of qualitative inquiry. Representing top scholars from around the world, the editors and contributors continue the tradition of synthesizing existing literature, defining the present, and shaping the future of qualitative research. The Fifth Edition contains 19 new chapters, with 16 revised making it virtually a new volume while retaining six classic chapters from previous editions. New contributors to this edition include Jamel K. Donnor and Gloria Ladson-Billings; Margaret Kovach; Paula Saukko; Bryant Keith Alexander; Thomas A. Schwandt and Emily F. Gates; Johnny Saldaña; Uwe Flick; Mirka Koro-Ljungberg, Maggie MacLure, and Jasmine Ulmer; Maria Elena Torre, Brett G. Stoudt, Einat Manoff, and Michelle Fine; Jack Bratich; Svend Brinkmann; Eric Margolis and Renu Zunjarwad; Annette N. Markham; Alecia Y. Jackson and Lisa A. Mazzei; Jonathan Wyatt, Ken Gale, Susanne Gannon, and Bronwyn Davies; Janice Morse; Peter Dahler-Larsen; Mark Spooner; and David A. Westbrook"--Publisher.

Contents:
Introduction: The discipline and practice of qualitative research / Norman K. Denzin and Yvonna S. Lincoln
Part 1. Locating the Field. A history of qualitative inquiry in social and educational research / Frederick Erickson
Ethics and politics in qualitative research / Clifford G. Christians
Ethics, research regulations, and critical social science / Gaile S. Cannella and Yvonna S. Lincoln
Part 2. Paradigms and Perspectives in Contention. Paradigmatic controversies, contradictions, and emerging confluences, revisited / Yvonna S. Lincoln, Susan A. Lynham, and Egon G. Guba
Feminist qualitative research in the millenium's first decade : developments, challenges, prospects / Virginia Olesen
Feminist qualitative research : emerging lines of inquiry / Marjorie L. DeVault
Critical race theory and the postracial imaginary / Jamel K. Donnor and Gloria Ladson-Billings
Doing Indigenous methodologies : a letter to a research class / Margaret Kovach
Critical pedagogy and qualitative research: advancing the bricolage / Joe L. Kincheloe, Peter McLaren, Shirley R. Steinberg, and Lilia D. Monzó
Methodologies for cultural and social studies in an age of new technologies / Paula Saukko
Queer/quare theory : worldmaking and methodologies / Bryant Keith Alexander
Part 3. Strategies of Inquiry. The marketization of research : implications for qualitative inquiry / Julianne Cheek
Case study methodology / Thomas A. Schwandt and Emily F. Gates
Performance ethnography / Judith Hamera
Ethnodrama and ethnotheatre : research as performance / Johnny Saldaña
Advancing a constructionist analytics / James A. Holstein
Evolving grounded theory and social justice inquiry / Kathy Charmaz, Robert Thornberg, and Elaine Keane
Triangulation / Uwe Flick
D ... a ... t ... a ..., data++, data, and some problematics / Mirka Koro-Ljungberg, Maggie MacLure, and Jasmine Ulmer
In the name of human rights : I say (how) you (should) speak (before I listen) / Antjie Krog
Critical participatory action research on state violence : bearing wit(h)ness across fault lines of power, privilege, and dispossession / María Elena Torre, Brett G. Stoudt, Einat Manoff, and Michelle Fine
Part 4. Methods of Collecting and Analyzing Empirical Materials. Observation in a surveilled world / Jack Bratich
Narrative inquiry : toward theoretical and methodological maturity / Susan E. Chase
Critical arts-based inquiry : performances of resistance politics / Susan Finley
The interview / Svend Brinkmann
Visual research / Eric Margolis and Renu Zunjarwad
Autoethnography and the other : performative embodiment and a bid for utopia / Tami Spry
Ethnography in the digital internet era : from fields to flows, descriptions to interventions / Annette N. Markham
Analyzing talk and text / Anssi Peräkylä and Johanna Ruusuvuori
Focus group research and/in figured worlds / George Kamberelis, Greg Dimitriadis, and Alyson Welker
Thinking with theory : a new analytic for qualitative inquiry / Alecia Y. Jackson and Lisa A. Mazzei
Creating a space in between : collaborative inquiries / Jonathan Wyatt, Ken Gale, Susanne Gannon, and Bronwyn Davies (JKSB)
Part 5. The Art and Practices of Interpretation, Evaluation, and Representation. Evidence, criteria, policy, and politics : the debate about quality and utility in educational and social research / Harry Torrance
Reframing rigor in qualitative inquiry / Janice Morse
Writing : a method of inquiry / Laurel Richardson and Elizabeth Adams St. Pierre
The elephant in the living room, or extending the conversation about the politics of evidence / Norman K. Denzin
Braiding narrative ethnography with memoir and creative nonfiction / Barbara Tedlock
Qualitative evaluation : methods, ethics, and politics with stakeholders / Peter Dahler-Larsen
Part 6. The Future of Qualitative Research. Qualitative research and global audit culture : the politics of productivity, accountability and possibility / Marc Spooner
Critical issues for qualitative research / David A. Westbrook
Epilogue: Toward a "refunctioned ethnography" / Yvonna S. Lincoln and Norman K. Denzin.

Contents:
Introduction to Enhanced Recovery Programs: A Paradigm Shift in Perioperative Care
Section I: The Science of Enhanced Recovery: Building Blocks for your Program
Peroperative Education
Medical Optimization and Prehabilitation
Preoperative Fasting and Carbohydrate Treatment
Bowel Preparation: Always, Sometimes, Never?
The Role of the Anesthesiologist in Reducing Surgical Stress and Improving Recovery
Prevention of Hypothermia
Prevention of Postoperative Nausea and Vomiting
Thromboprophylaxis
Surgical Site Infection Prevention
Fluid Management
Postoperative Ileus: Prevention and Treatment
Choosing Analgesia to Facilitate Recovery
Early Nutrition and Early Mobilization: Why They Are Important and How to Make it Happen
Management of Tubes, Drains, and Catheters
Hospital Recovery and Full Recovery
Section II: Creation and Implementation of an Enhanced Recovery Program
Overcoming Barriers to the Implementation of an Enhanced Recovery After Surgery Program
Introducing Enhanced Recovery Programs into Practice: Lessons Learned from The ERAS® Society Implementation Program
Enhanced Recovery Programs: Making the Business Case
Audit: Why and How
Why Add an ERP to a Laparoscopic Case: The Colorectal Experience
Section III: Examples of Enhanced Recovery Programs
Enhanced Recovery Programs for Colorectal Surgery: University Hospitals Case Medical Center
Enhanced Recovery Programs for Colorectal Surgery: The Guilford: (UK) Experience
Setting up an Enhanced Recovery Program Pathway for Bariatric Surgery: Current Evidence into Practice
Enhanced Recovery Pathways in Hepato-pancreato-biliary Surgery
Enhanced Recovery Programs for Upper Gastrointestinal Surgery: How I Do It
Department-Wide Implementation of an Enhanced Recovery Pathway
The ERAS® Society
SAGES SMART Enhanced Recovery Program.

Summary: This book is intended as a definitive, state of the art guide to robotic surgery that summarizes the field for surgeons at all levels. More specifically, its goals are threefold: to review the basics of robotic surgery, including fundamental principles, technology, operating room setup, and workflow; to describe and illustrate the procedures most commonly performed in a robotic operating room; and to discuss key issues relating to cost, adoption, and training. Procedures from many surgical disciplines are included, which aid robotic surgeons in supervising and assisting colleagues in these disciplines and simultaneously heighten their awareness of the tricks and tools used in other disciplines that can be retasked for their own purposes. In addition, the future prospects for robotic surgery, including anticipated developments in equipment, are discussed. The SAGES Atlas of Robotic Surgery is an excellent aid for residents and fellows entering the field, as well as a welcome update on recent progress for practicing robotic surgeons and an ideal primer for senior surgeons adapting these new technologies to their current practice.

Contents:
Surgical Endoscopy
A Historical Perspective
Endoscopic Tools
Instruments
Operating Platforms for Surgical Endoscopy
Endoscopic Energy Sources
Training in Advanced Endoscopic Procedures
Endoscopic Management of Bleeding
Stricture Management- Interventional Options
Endoscopic Stent Placement and Suturing: Management of Gastrointestinal Anastomotic Leaks
Endoscopic Treatment of Gastrointestinal Fistulas
Enteral Access: Percutaneous Endoscopic Gastrostomy, Gastrostomy- Jejunostomy, and Jejunostomy
Endolumenal GERD Therapies
Barrett's Esophagus
Radiofrequency (RF) and Other Ablation Modalities
Endoscopic Mucosal Resection: Upper Gastrointestinal Tract
Endoscopic Mucosal Resection: Colon and Rectum
Endoscopic Submucosal Dissection: Upper Gastrointestinal Tract
Endoscopic Submucosal Dissection: Colon and Rectum
Per Oral Endoscopic Myotomy (POEM)
Endoscopic Interventions for the Thoracic Esophagus- Zenker's and other Diverticula
Endoscopic Retrograde Cholangiopancreatography (ERCP)
Advanced ERCP: Cholangioscopy and through the Scope Imaging
Interventional Endoscopic Ultrasound
Hybrid Laparoscopic and Endoscopic Techniques: Upper Gastrointestinal Tract
Hybrid Laparoscopic and Endoscopic Techniques: Colon and Rectum
Primary Endoscopic Treatments for Morbid Obesity
Endoscopic Revision Procedures after Bariatric Surgery
Natural Orifice Trans-lumenal Endoscopic Surgery (NOTESTM)
Future Directions for Endoscopic Operations. .

Summary: This book provides a concise summation of current operative decision making and techniques for situations faced by the on-call general surgeon. This manual covers pertinent topics such as minimally invasive surgery in the trauma setting, surgical emergencies in the bariatric patient, and treatment of emergencies in pregnancy, cirrhotics, and anti-coagulated patients. The experts at SAGES pooled their knowledge and created this manual to describe the most up-to-date treatment options for the emergent surgical patient. The SAGES Manual of Acute Care Surgery aligns with the new SAGES UNIVERSITY MASTERS Program and supplements the Master's Program Acute Care Pathway. Its goal is to help educate surgeons to bring the optimum care to the patients that they are called to see in their emergency rooms, and to help surgeons progress from the competent to the proficient and finally to the mastery level.

Contents:
SAGES University MASTERS PROGRAM: Acute Care Pathway
Appendicitis
Cholecystectomy
Foregut and Hindgut Perforations
Small Bowel Obstruction
Colon Emergencies
Acute Gastrointestinal Bleeding
Emergency hernia surgery: What to know when evaluating a patient with an incarcerated hernia
Bariatrics
Paraesophageal Hernia
Necrotizing Pancreatitis
Acute Complications of Inflammatory Bowel Disease
Minimally Invasive Techniques in Trauma: Above and Below the Diaphragm
The Difficult Patient
Incorporating ACS Into Your Practice
The Future of Acute Care Surgery: From Divergence to Emergence, and Convergence. The Evolution in General Surgery Continues.

Summary: "The SAGES Manual of Bariatric Surgery, Second Edition, covers each of the fundamental components of care for the bariatric patient, and we have extended the list of topics to include highly relevant but rarely published issues such as domestic and international surgical tourism, pregnancy, and innovative devices in the premarket setting, among others. This second edition also aligns with the novel SAGES Masters Program Bariatric Pathway, and, as such, the reader will appreciate an innovatively organized text reflecting this"--taken from Preface.

Contents:
Part I: SAGES masters program. Chapter 1: Introduction: SAGES masters program bariatric pathway ; Chapter 2: Masters program bariatric pathway: adjustable gastric band ; Chapter 3: Masters program bariatric pathway: laparoscopic sleeve gastrectomy ; Chapter 4: Master's program bariatric pathway: Roux-en-Y gastric bypass ; Chapter 5: Master's program bariatric pathway: revision of adjustable gastric band
Part II: Bariatric programs in 2018. Chapter 6: Bariatric surgery: a historical perspective ; Chapter 7: The obesity epidemic ; Chapter 8: Patient selection prior to bariatric surgery ; Chapter 9: The role of the advanced practice provider in the management of the bariatric patient ; Chapter 10: The role of the social worker in the mangement of the bariatric patient ; Chapter 11: The role of the registered dietitian in the managment of the bariatric patient ; Chapter 12: The role of the physical therapist in the management of the bariatric patient ; Chapter 13: The role of the obesity medicine physician in the management of the bariatric patient ; Chapter 14: The role of the psychologist in the management of the bariatric patient ; Chapter 15: Preoperative checklist for bariatric surgery ; Chapter 16: Postoperative care pathways for the bariatric patient ; Chapter 17: The MBSAQIP (Metabolic and Bariatric Surgery Accreditation and Quality Improvement Program) comprehensive bariatric program (MBSAQIP-ASMBS/ACS) ; Chapter 18: Establishing a comprehensive bariatric surgery program ; Chapter 19: Long-term follow-up of bariatric patrients
Part III: Treatment. Chapter 20: Medically supervised weight loss programs ; Chapter 21: Index endoscopic restrictive and other devices in obesity treatment: techniques and outcomes ; Chapter 22: Index endoscopic malabsorptive procedures in obesity treatment: techniques and outcomes ; Chapter 23: Neurohormonal procedures in obesity treatment ; Chaper 24: The genetic and microbial influences in obesity ; Chapter 25: The role of preoperative, intraoperative, and postoperative diagnostic endoscopy in bariatric surgery ; Chapter 26: long-term nutritional/metabolic sequelae of bariatric surgery ; Chapter 27: Robotic index bariatric surgery ; Chapter 28: Duodenal switch: technique and outcomes ; Chapter 29: Comparative surgical outcomes in bariatric surgery
Part IV: Complications. Chapter 30: Complications of endolumenal bariatric therapies (EBTs) ; Chapter 31: Complications of adjustable gastric banding ; Chapter 32: Complications of sleeve gastrectomy ; Chapter 33: Complications of Roux-en-Y gastric bypass ; Chapter 34: Complications of biliopancreatic diversion and duodenal switch
Part V: Revision and conversion. Chapter 35: Weight recidivism after bariatric surgery: evaluation and implications ; Chapter 36: Revision endolumenal therapies for weight recidivism ; Chapter 37: Conversion and revisional surgery: sleeve gastrectomy ; Chapter 38: Conversion and revisional surgery: Roux-en-Y gastric bypass ; Chapter 39: Conversional and revisional surgery: duodenal switch ; Chapter 40: Robotic conversion and revisional surgery
Part VI: Special circumstances. Chapter 41: Bariatric emergencies for the general surgeon ; Chapter 42: Social media and bariatric surgery ; Chapter 43: Bariatric tourism: bidirectional and in the United States ; Chapter 44: Pregnancy and bariatric surgery ; Chapter 45: Solid organ transplantation and bariatric surgery ; Chapter 46: Adolescents and bariatric surgery: techniques and outcomes ; Chapter 47: Esophageal reflux disease before and after bariatric surgery.

Summary: This book provides the standard for the current state of biliary surgery in the 21st century and aims to help the surgeon progress from the competent, to the proficient, and finally to the mastery level. This guidebook also gives insight into modern evaluation and management. The highlights emphasize what is both feasible and safe from a minimally invasive approach in biliary surgery. The concept of safe cholecystectomy is defined and expounded on in detail. The difficult cholecystectomy is given ample coverage to include management of intraoperative bile duct injury, indications and techniques of subtotal cholecystectomy, and special attention to intraoperative diagnostic imaging that serve as adjuncts, including cholangiograpy, ultrasound, as well as indocyanine green biliary fluorescence. Furthermore, the evolution of treatment of choledocohlithiasis has evolved the most in recent years, and thus requires an extensive discussion of the non-operative and operative management of bile duct stones. The SAGES Manual of Biliary Surgery serves as an important contribution to the medical literature sponsored by SAGES, an international leading authority in gastrointestinal surgery with a keen interest in safe and proficient biliary surgery. Leaders in the field of biliary surgery impart their insight and considerable experience in the chapters planned for this manual. The intent for this manual is to be the cited resource for high quality and applicable knowledge for the treatment of benign biliary disease.

Contents:
Introduction to Biliary Manual
Biliary Anatomy
Basic Principles of Safe Laparoscopic Cholecystectomy
Preoperative Optimization for Elective Cholecystectomy
Preoperative Imaging in Patients Undergoing Cholecystectomy
Choosing the Best Timing for Cholecystectomy
When to Perform a Cholecystectomy after Percutaneous Cholecystostomy Tube Placement
Intraoperative Cholangiography (IOC): Important Aid in Biliary and Common Bile Duct Surgery
Intraoperative Indocyanine Green during Cholecystectomy
Laparoscopic Biliary Ultrasound
The Difficult Cholecystectomy
Non Operative Management of Common Bile Duct Stones: ERCP & Other Techniques (Lithotripsy)
Common Bile Duct Exploration
Management of Common Bile Duct Injury
Operative Management of Bile Duct Injury in the Presence of Prior Roux-en-Y
Management of Common Bile Duct Tones in the Presence of Prior Roux-en-Y
Advanced Biliary Procedures.

Summary: This book provides essential didactic content for the SAGES University Masters Program Colorectal Surgery Curriculum. Surgeons seeking to complete the competency, proficiency, or mastery curriculum of the MASTERS Colorectal Pathway for a particular anchoring colorectal procedure will find relevant educational content in this SAGES Manual. Written by experts in the field, each chapter provides detailed guidance on preoperative and peri-procedural considerations for right and left elective and emergency colorectal resections, for both benign and malignant pathologies. Technical pearls and strategies to manage pitfalls and complications are also extensively reviewed along with detailed guidance for both laparoscopic and robotic procedures. The SAGES Manual of Colorectal Surgery provides a wealth of practical guidance to surgeons along their journey to progress from competency to mastery in various minimally invasive approaches to colorectal surgery.

Contents:
SAGES University MASTERS PROGRAM: Colorectal Pathway
Masters Program Colorectal Pathway: Laparoscopic Right Colectomy for Benign Disease
Masters Program Colorectal Pathway: Laparoscopic Left and Sigmoid Colectomy for Benign Disease
Master Program Colorectal Pathway: Laparoscopic Splenic Flexure Release (Tips and Tricks)
Master Program Colorectal Pathway: Laparoscopic Left Colon Resection for Complex Inflammatory Bowel Disease
Laparoscopy Versus Open Colorectal Surgery: How Strong is the Evidence?
Debunking Enhanced Recovery Protocols in Colorectal Surgery: Minimal Requirements for Maximum Benefit
Bowel Preparation in Colorectal Surgery: Impact on SSIs and Enhanced Recovery Protocols
Checklist for Patients and OR Team in Preparation for Laparoscopic Colorectal Surgery
Essentials on Troubleshooting during Laparoscopic Colorectal Surgery
Principles of Complete Mesocolic Excision for Colon Cancer
Unexpected Findings at Appendectomy
Laparoscopic Right Colectomy for Malignant Disease
Laparoscopic Right Colectomy: Options for Ileocolonic Reconstruction
Robotic Right-Sided Colon Resection: Unique Considerations and Optimal Set-Up
Advanced Laparoscopic Right Colectomy Techniques for Crohn's and Reoperative Surgery
Laparoscopic Left and Sigmoid Colectomy for Malignant Disease
Laparoscopic Left and Sigmoid Colectomy: Options for Colonic and Colorectal Reconstruction
Robotic Left-Sided Colon Resections: Unique Considerations and Optimal Set-Up
Key Steps During Hartmann's Procedures to Facilitate Minimally Invasive Hartmann's Reversal
Laparoscopic and Robotic Hartmann's Reversal: Strategies to Avoid Complications
Principles of Rectal Cancer Management: Preoperative Staging, Neoadjuvant Treatment, Basic Principles of TME, and Adjuvant Treatment
Laparoscopic Low Anterior Resection for Rectal Cancer: TME Planes and Surgery of the Upper and Mid Rectum
Robotic Low Anterior Resection: Unique Considerations and Optimal Setup
Unexpected Findings During Laparoscopic Colectomy for Cancer: Techniques and Strategies
The Role of Laparoscopy in the Management of Bowel Obstruction
Large Bowel Obstruction: When Should Colon Stenting Be Considered as First-Line Strategy?
Minimally Invasive Management of Complicated Sigmoid Diverticulitis in the Emergency Setting: Patient Selection, Prerequisite Skills, and Operative Strategies
Minimizing Colorectal Anastomotic Leaks: Best Practices to Assess the Integrity and Perfusion of Left-Sided Anastomoses
Intraoperative Air Leak, Colonic Ischemia, or Tension: How To Salvage the Failed Anastomosis
Minimizing Conversion in Laparoscopic Colorectal Surgery: From Preoperative Risk Assessment to Intraoperative Strategies
Laparoscopic Colorectal Surgery in the Obese and Morbidly Obese Patient: Preoperative Strategies and Surgical Techniques
The Challenge of the Transverse Colon Tumor: Laparoscopic Techniques and Strategies
Laparoscopic Total Abdominal Colectomy for Emergent and Elective Indications: Perioperative Considerations and Techniques
Organ-Preserving Strategies in the Management of Fulminant Clostridium Difficile Colitis
Optimizing Stoma Function and Quality of Life: Best Practices in Planned and Unplanned Stoma Creation
Prophylactic Approaches for Parastomal Hernia Formation during Laparoscopic Creation of Permanent End-Stomas: Rationale, Techniques, and Outcomes
Transanal Endoscopic Surgery for Benign Rectal Lesions: Preparation and Surgical Techniques
Transanal Endoscopic Surgery for Rectal Cancer: Indications, Staging, and Perioperative Considerations
Advanced Techniques for Specimen Extraction During Laparoscopic Colorectal Surgery.

Summary: This book addresses all aspects of endoscopy from scope and tower basics to the more advanced interventional procedures like endoscopic retrograde cholangiopancreatography, per-oral esophageal myotomy, and percutaneous endoscopic gastrostomy. It covers a broad range of topics in order to remain relevant to the surgical subspecialist, the community general surgeon, the surgical fellow interested in endolumenal and transluminal procedures, and the surgical resident interested in the very basics of endoscopy. The table of contents is intentionally designed to mirror the Flexible Endoscopy curriculum currently being implemented for all minimally invasive, advanced GI and surgical endoscopy fellowships. The chapters are broken up into five parts. The first part introduces the SAGES Masters Program, followed by parts that cover flexible endoscopy basics, flexible endoscopy procedures, and finally bariatric flexible endoscopy. Written by experts and thought leaders in their fields, The SAGES Manual of Flexible Endoscopy serves as a valuable resource for surgeons of all training and skill levels to better grasp an overview of modern endoscopy practice.

Summary: This book lays the foundation in understanding the foregut through review of the anatomy and physiology, followed by subsequent chapters focusing on the diagnosis and management of specific benign diseases of the foregut, such as gastroesophageal reflux disease and diaphragmatic hernia, Barrett's esophagus, disorders of esophageal dysmotility, benign esophageal and gastric tumors, peptic ulcer disease and gastric outlet obstruction, and gastroparesis. Written by experts in the field, each of these sections addresses the evaluation and management of the disease process, technical conduct of the most common endoscopic and surgical procedures, postoperative management including complications, and revisional operations. Additionally, expert commentary will serve to highlight and clarify controversies in the field.

Contents:
SAGES University MASTERS PROGRAM: Foregut Pathway
Anatomy and Physiology of the Esophagus and Lower Esophageal Sphincter
Anatomy and Physiology of the Stomach and Pylorus
Anatomic and Physiologic Tests of Esophageal and Gastric Function
The history of hiatal hernia and antireflux surgery
Evaluation of GERD: Symptoms and Disease Classification
Preoperative Workup of GERD
Identifying Patients with Eosinophilic Esophagitis
Laryngo-Pharyngeal Reflux (LPR)
Management of Esophageal Peptic Stricture
Medical Management of GERD
Laparoscopic Antireflux Surgery: Nissen and Partial fundoplications
Laparoscopic Anti-Reflux Surgery: Magnetic Gej Augmentation
Laparoscopic Anti-Reflux Surgery: Laparoscopic Roux-en-Y Gastric Bypass
Endoscopic Reflux Treatments
Endoluminal Treatment for Gastroesphogeal Reflux Disease
Laparoscopic Antireflux Surgery: Reoperations at the Hiatus
Classification and Evaluation of Diaphragmatic Hernias
Laparoscopic Hiatal Hernia Repair
Transthoracic Hiatal Hernia Repair
Esophageal lengthening procedures
Management of Acute Gastric Volvulus
Surgical Management: Other Diaphragmatic Hernias in Adults
Expert Commentary: Mesh Reinforcement of Hiatal Closure
Historical Perspective: Evolution of the Diagnosis and Management of Barrett's Esophagus
Epidemiology of Barrett's Esophagus and Esophageal Cancer
Diagnosis and Surveillance of Barrett's Esophagus
Radiofrequency Ablation for Dysplastic Barrett's Esophagus
Endoscopic mucosal resection for Barrett's related Neoplasia
Role Of Photodynamic Therapy And Cryotherapy For Management Of Barrett's Esophagus
Expert Commentary: Surveillance versus Ablation for Patients with Low Grade Dysplasia
Historical Perspective: History of the Surgical Management of Achalasia
Epidemiology, Evaluation, and Classification of Achalasia and Other Esophageal Motility Disorders
Medical Management of Achalasia
ENDOSCOPIC MANAGEMENT OF ACHALASIA: Botulinum Toxin And Pneumatic Dilation
Surgical Management of Achalasia: Laparoscopic Heller Myotomy
Surgical Management of Achalasia: Thoracoscopic Myotomy
Surgical Management of Achalasia: Per Oral Endoscopic Myotomy
Surgical Management of Achalasia: Recurrent Dysphagia
Expert Commentary: Laparoscopic versus Endoscopic Myotomy for Achalasia
Diagnosis and Medical Management of Other Esophageal Motility Disorders
Other Esophageal Motility Disorders: Role For Laparoscopic or Endoscopic Myotomy
Evaluation of Esophageal Diverticula
Cricopharyngeal Diverticulum: Open Repair
Zenker's Diverticulum: Transoral Repair
Epiphrenic and Mid-Esophageal Diverticula
A Laparoscopic Approach to Epiphrenic Diverticula
Evaluation of Benign Submucosal Tumors
Thoracoscopic Management of Benign Submucosal Tumors
Benign Esophageal and Gastric Tumors: Laparoscopic Management of Benign Submucosal Tumors
Endoscopic Management of Benign Submucosal Tumors
The Evolution of Management of Peptic Ulcer Disease
Evaluation of peptic ulcer disease
Risk Factor Modification in Patients with Peptic Ulcer Disease
Medical Management of Peptic Ulcer Disease
Surgical Management: Truncal, Selective, and Highly Selective Vagotomy
Surgical Management: Vagotomy and Pyloroplasty
Surgical Management: Billroth I
Surgical Management: Billroth II
Surgical Management: Roux-en-Y Reconstruction
Post-Gastrectomy Syndromes
Evaluation and Management: Recurrent Peptic Ulcer Disease
Peptic Ulcer Disease: Deciding What Procedure When
Etiology and Diagnosis of Gastric Outlet Obstruction
Medical and Endoscopic Management of Gastric Outlet Obstruction
Surgical Management: Resection and Reconstruction vs. Drainage
Surgical Management: Pyloroplasty Options
Evaluation and Classification of Gastroparesis
Medical Management of Gastroparesis: Diet and Medications
Endoscopic Management: Interventions at the Pylorus
Endoscopic Management: Decompression and Feeding
Gastroparesis
Surgical Management: Pyloroplasty
Gastrectomy for Gastroparesis
Expert Commentary: Algorithm for the Treatment of Gastroparesis.

Contents:
Primary Groin Pain
Musculoskeletal anatomy of groin pain
Neuroanatomy of groin pain
History: High yield questions to the patient as part of the history/intake
Physical Examination: Highly sensitive and specific exam findings
Inguinal Hernia, Femoral Hernia
Non-Hernia Causes: Adductor Tendinitis, Osteitis Pubis, Epididymitis, Varicocele, Referred Pain (from hip (e.g., labral tear), back (e.g., radiculopathy, sacroiliitis, ankylosing spondylitis))
Sports Hernia
Chronic pelvic pain in women (endometriosis, pelvic floor dysfunction, round ligament syndrome or masses, ovarian cyst disease, occult hernias)
Occult Hernias: Typical presentation, symptoms, exam findings, radiologic evaluation
Secondary Groin Pain
Causes of Pain from Anterior Repair
Causes of Pain from Posterior Repair
Algorithm for Pain Management
Pharmacologic Management
Interventional Procedures: Nerve block, epidurals, ablation, neurostimulators
Radiologic findings of mesh and meshoma
Dermatomal Mapping: Pre/post-operative assessment
Quantitative Sensory Testing (QST)
Management of Recurrence
Open Triple Neurectomy vs selective neurectomy
Laparoscopic Triple Neurectomy
Meshoma Removal (Lap and open)
Treatment of Orchialgia
Selected Topics
Prevention of Pain: Open Technique (include mesh-specific tips)
Prevention of Pain: Laparoscopic Technique (include technical tips)
Prophylactic Neurectomy versus Pragmatic Neurectomy
Selective Neurectomy versus Triple Neurectomy
Patient Narratives
Emerging patient and provider care communities (social media for patients with groin pain and for providers who care for patients with groin pain)
Value-based clinical quality improvement- learning to improve the value of treating patients with groin pain
Team based approach for treating patients with chronic groin pain.

Summary: In this thoroughly revised second edition of the frequently downloaded manual, The SAGES Manual of Quality, Outcomes, and Patient Safety. A panel of experts update and expand their survey of the many factors that influence quality in the world of surgery, surgical outcomes, and threats to patient safety. Among the highlights include a section devoted to threats to quality and outcomes and safety, such as surgeon wellness and burnout, disruptive behavior, second victims, the surgeon with declining skills, and maintaining quality in the setting of a crisis. Another all-new section focuses on surgical controversies, such as whether or not to use robotic surgical technology and whether or not it influences surgical outcomes; whether or not routine cholangiography reduces the common bile duct injury rate; whether or not having a consistent operating room team influences surgical outcomes, and whether a conflict of interest truly influences surgical quality. Further, this manual updates chapters on surgical simulation, teamwork and team training, teleproctoring, mentoring, and error analysis. State-of-the-art and readily accessible, The SAGES Manual of Quality, Outcomes, and Patient Safety, Second Edition will offer physicians strategies to maintain surgical quality in a rapidly changing practice environment the tools they require to succeed.

Summary: This SAGES manual will help educate and advise our new and recent surgical graduates on entering the job market. From how to find a job, to contract negotiations, to research and grant proposals, this manual offers pertinent strategies crucial to both surgical and non-surgical subspecialty fields. Chapters focusing on work-life balance and finding a mentor offer helpful insight to prevent burnout and optimize one's new career. The SAGES Manual: Transitioning to Practice will fill the gap in resident education and prove a useful text for residents, fellows and recent graduates as well as practicing surgeons in all subspecialties of surgery.

Contents:
Historical background of spinal sagittal balance / Pierre Roussouly and Nishant Nishant
The acquisition of human verticality / Christine Tardieu and Martin Haeusler
From the head to the feet : anatomy of the upright position / Jean Marc Vital, Jacques Sénégas, and Jean-Etienne Castelain
Modeling of the spine / Carl-Eric Aubin and Xiaoyu Wang
Sagittal balance : the main parameters / João Luiz Pinheiro-Franco and Pierre Roussouly
Spinal curves segmentation and lumbar lordosis classification / Amer Sebaaly and Pierre Roussouly
Normative values of sagittal balance in children and adults / Jean-Marc Mac-Thiong and Fethi Laouissat
Sagittal balance in the elderly / Martin Gehrchen
Local stresses : segmental mechanism of low back pain and degeneration. Stresses according to spinal orientation
contact forces theory / Pierre Roussouly and Amer Sebaaly
Mechanisms of spinal degeneration according to spinopelvic morphotypes / João Luiz Pinheiro-Franco and Pierre Roussouly
Sagittal imbalance compensatory mechanisms / Martin Gehrchen
Isthmic lytic spondylolisthesis : the physiopathology, classification, and treatment better explained by the sagittal balance / Hubert Labelle, Jean-Marc Mac-Thiong, Stefan Parent, and Pierre Roussouly
Degenerative spondylolisthesis : does the sagittal balance matter? / Cédric Y. Barrey, Charles Peltier, Amir El Rahal, and Pierre Roussouly
Degenerative (aging) spine : a challenge for contemporaneous societies / J.C. Le Huec, W. Thompson, A. Leglise, M. Petit, and T. Cloché
Scheuermann's kyphosis / Stefan Parent, Abdulmajeed Alzakri, and Hubert Labelle
Cervical sagittal alignment and cervicarthrosis / Darryl Lau and Christopher P. Ames
Advantages and limitations of the SRS-Schwab classification for adult spinal deformity / Hideyuki Arima, Leah Y. Carreon, and Steven D. Glassman
Specificities in growing spine / Shahnawaz Haleem and Colin Nnadi
Sagittal balance incidence on treatment strategy in AIS / Stephan Parent
From pathological to normal shapes in adult scoliosis / Pierre Roussouly and Amer Sebaaly
Sagittal balance treatment strategy in a posterior approach / Fethi Laouissat and Pierre Roussouly
Adult scoliosis treatment with an anterior approach / Anthony M. DiGiorgio, Mohanad Alazzeh, and Praveen V. Mummaneni
Techniques for spine osteotomies and clinical applications / Ibrahim Obeid and Derek T. Cawley
Surgical failures mechanisms and their treatment / Pierre Roussouly, Hyoungmin Kim, Amer Sebaaly, and Daniel Chopin.

Contents:
Anatomy, biogenesis, and regeneration of salivary glands / Holmberg, K.V.; Hoffman, M.P.
Salivary secretion : mechanism and neural regulation / Proctor, G.B.; Carpenter, G.H.
Salivary pellicles / Lindh, L.; Aroonsang, W.; Sotres, J.; Arnebrant, T.
Antimicrobial defense systems in saliva / Nieuw Amerongen, A.V.; van't Hof, W.; Ligtenberg, A.J.M.; Veerman, E.C.I.
Saliva and wound healing / Veerman, E.C.I.; Ligtenberg, A.J.M.; Brand, H.S.
Role of saliva in oral food perception / Neyraud, E.
Lubrication / Yakubov, G.E.
Saliva diagnostics : utilizing oral fluids to determine health status / Schafer, C.A.; Schafer, J.J. ; Yakob, M.; Lima, P.; Camargo, P.; Wong, D.T.W.
The use of saliva markers in psychobiology : mechanisms and methods / Bosch, J.A.
Xerostomia / Delli, K.; Spijkervet, F.K.L.; Kroese, F.G.M.; Bootsma, H.; Vissink, A.
Drooling / Silvestre-Donat, F.J.; Silvestre-Rangil, J.
Salivary gland diseases : infections, sialolithiasis, and mucoceles / Delli, K.; Spijkervet, F.K.L.; Vissink, A.

Summary: Saliva as a unique sample for health assessment is gaining attention among researchers of different fields in the last 20 years; being reflected in an impressive increase in the number of papers published studying saliva from different biological aspects in human and veterinary species. Once deemed merely a digestive juice is now considered a biological fluid capable of communicating information about physiopathological processes occurring in organisms, since saliva has been shown to contain molecular and bacterial compounds that can change in response to local and systemic pathologies. Furthermore, the interest of saliva as a diagnostic, prognostic and monitoring biofluid is forced by its non-invasive nature being of easy and inexpensive sampling, involving only minimal discomfort and allowing the collection of multiple/repeated specimens at anytime, anywhere and without need for specialized staff. In this contributed volume, the authors bring together, summarize and reflect the generated knowledge about saliva as a source of biomarkers for health and welfare evaluation in humans and animal models. This volume also highlights the importance of confounding factors, such as sampling methods, flow, total protein content, contamination, or storage. This book will serve as a manual for graduates, practitioners and researchers by providing general ideas about the possibilities and utilities of saliva in clinical practice or investigation, and indicating the main cautions each should have in mind before saliva usage.

Contents:
Intro
Preface
Acknowledgements
Contents
Part I: Saliva Basics
Chapter 1: Salivary Glands' Anatomy and Physiology
1.1 Salivary Glands' Anatomy and Histology
1.1.1 Types of Salivary Glands
1.1.2 Histology
1.1.3 The Excretory Ducts in Major Salivary Glands
1.2 Saliva Secretion
1.2.1 Regulation
1.2.1.1 Salivary Gland Innervation Routes
1.2.1.2 Neurotransmitters Released by Autonomic Nerves Innervating Salivary Glands
1.2.2 Pathways of Saliva Secretion
1.3 Saliva
1.3.1 Composition
1.3.2 Function
1.4 Conclusions
References 2.3.2.2 How Can Saliva Influence Food Texture Perception in Mouth?
2.3.3 Saliva and Aroma
2.4 Changes in Saliva Composition in Response to Ingestion: Can This Affect the Sensory Perception of Subsequently Ingested Food?
2.5 How Saliva Changes Under Pathological States Can Affect Oral Food Perception
2.6 Conclusion
References
Chapter 3: Saliva as a Non-invasive Sample: Pros and Cons
3.1 Collection Methods
3.1.1 Methods for Obtaining Total Unstimulated Saliva
3.1.1.1 Drainage
3.1.1.2 Spitting
3.1.1.3 Ejector (Saliva Aspiration)
3.1.1.4 Syringe Collection 3.1.1.5 Cotton
3.1.2 Methods for Obtaining Total Stimulated Saliva
3.1.2.1 Mechanical Stimulation Techniques
3.1.2.2 Chemical Stimulation Techniques
3.1.2.3 Stimulation with Pharmacological Substance
3.1.2.4 Electrostimulation
3.1.2.5 Low-Power Laser Stimulation
3.1.2.6 Acupuncture
3.1.3 Methods for Collection of Partial Saliva
3.1.4 Saliva Collection Techniques in Animals
3.2 Advantages and Disadvantages of Using Saliva
3.2.1 Advantages
3.2.2 Disadvantages
References Chapter 2: Saliva in Ingestive Behavior Research: Association with Oral Sensory Perception and Food Intake
2.1 Introduction
2.2 Oral Food Perception
2.2.1 Mechanisms of Basic Taste, Aroma and Oral Tactile Perception
2.2.1.1 Taste
2.2.1.2 Food Aroma Perception
2.2.1.3 Food Texture (Tactile) Perception
2.2.2 How Oral Food Perception Influences Food Acceptance and Choices
2.3 Saliva Composition and Food Sensory Perception
2.3.1 Saliva and Basic Tastes
2.3.2 Saliva and Tactile Sensations
2.3.2.1 The Role of Saliva in Astringency Development Chapter 4: Methodology Assays for the Salivary Biomarkers' Identification and Measurement
4.1 The Concept of Biomarker and the Potential of Saliva as a Diagnostic Fluid
4.2 Methodology Assays
4.2.1 Spectrophotometric Assays
4.2.1.1 Ultraviolet and Visible (UV-Vis) Absorption Spectroscopy
4.2.1.2 Atomic Spectrophotometry
4.2.1.3 Near Infrared Spectrophotometry
4.2.1.4 Flow Injection Spectrophotometric Analysis
4.2.2 Immunoassays (IAs)
4.2.2.1 Enzyme-Linked Immunoassays (EIAs)
4.2.2.2 AlphaLisa
4.2.2.3 Chemiluminescence Immunoassays (CLIA)

Summary: "Saliva Protection and Transmissible Diseases provides a review of saliva protection, raising debate on micro-organisms potentially transmissible in saliva, and also considering the evidence on diseases that may be transmitted by kissing. Saliva is a complex body fluid essential to health, especially mastication, swallowing and speech, and hyposalivation can lead to dysfunction and even infection. More serious pathogens, such as herpes viruses and papillomaviruses can be conveyed by kissing, as can potentially lethal micro-organisms present in some saliva, such as meningococci, fungal organisms and Ebola viruses.Stipulates the defensive roles of saliva, an important topic not previously reviewed in-depth in literature. Provides awareness that saliva also transmits infectious agents that can produce serious or even lethal diseases. Gives understanding that kissing may be an at-risk practice"-- Provided by publisher.

Summary: "This book provides the first comprehensive overview of the emerging field of interdisciplinary salivary bioscience. It serves as a foundational reference guide to the collection, analysis, and interpretation of salivary data, as well as its myriad applications in medicine, surveillance and public health. The ease and non-invasive nature of saliva collection makes it highly useful in diverse fields such as pediatrics, dentistry, neuroscience, psychology, animal welfare and precision medicine. This book introduces students and scientists alike to the vast potential of salivary bioscience in both research and practice." -- Resource home page

Contents:
Intro
Preface
Acknowledgements
Contents
Editors and Section Editors
Part I: What Is Salivary Bioscience, Why Is It Important, and How Do We Study It?
Chapter 1: Foundations of Interdisciplinary Salivary Bioscience: An Introduction
References
Chapter 2: Salivary Gland Anatomy and Physiology
2.1 Basic Anatomy of the Oral Cavity
2.2 Salivary Gland Anatomy
2.3 Saliva Composition
2.4 Functions of Saliva
2.5 Salivary Flow
2.6 Neural Regulation of Salivary Glands
2.7 Summary
References 3.3.1 Cold Chain Management and Additives
3.3.2 Prioritizing Analyte Testing
3.4 Concluding Comments
References
Chapter 4: Analytical Strategies and Tactics in Salivary Bioscience
4.1 Introduction
4.2 Power Analysis with Salivary Biomeasure Data
4.3 Early Processing of Salivary Biomeasure Data: Unique Challenges and Solutions
4.3.1 Examining Data Parameters Related to In-Laboratory Saliva Processing Procedures
4.3.2 Examining and Addressing Missing, Unreliable, or Invalid Values
4.3.3 Approaches for Addressing Unreliable, Invalid, and Missing Data 4.3.4 Examining the Distribution of the Data
4.3.5 Computing Composites and Indicators of Individual Differences
4.3.5.1 Within-Individual Analyte Change
4.4 Advanced Statistical Analysis of Salivary Biomeasure Data
4.4.1 Conceptualizing Biomeasures Within a Mediation Framework
4.4.2 Modeling Coordination Among Multiple Analytes in Cross-Sectional Studies
4.4.3 Modeling Individual Biomeasure Response Trajectories Using Multilevel Modeling
4.4.4 Additional Applications of Multilevel Modeling
4.4.4.1 Modeling Multiple Biomeasure Trajectories with Multilevel Modeling 4.4.4.2 Modeling Biomeasure Trajectories from Multiple Individuals with Multilevel Modeling
4.4.5 Isolating Trait, State, and Error Components of Salivary Biomeasure Data Using Latent Variable Modeling
4.5 Conclusion
References
Part II: Physiology and Development Research and Applications
Chapter 5: Salivary Bioscience, Human Stress and the Hypothalamic-Pituitary-Adrenal Axis
5.1 History of Salivary Bioscience in Stress Psychoneuroendocrinology
5.2 Current Status of Knowledge in Psychoneuroendocrinology
5.2.1 Stress Reactivity Studies Chapter 3: Saliva Collection, Handling, Transport, and Storage: Special Considerations and Best Practices for Interdisciplinar...
3.1 Saliva Collection Considerations Related to Research Design
3.1.1 Environmental Factors
3.1.2 Biologically Relevant Factors
3.2 Data Collection Methods
3.2.1 Adults and Older Children
3.2.2 Adult and Older Children
3.2.3 Small Children and Infants
3.2.4 Geriatric and Special Populations
3.2.5 Nonhuman Animals
3.2.6 Practical (Everyday) Sources of Variability
3.3 Sample Handling, Transport, and Storage

Summary: This clinically oriented book provides a comprehensive update on the biology, diagnosis, and treatment of salivary gland cancer. Detailed information is presented on molecular characterization and radiological staging, and a series of treatment-related chapters describe the different surgical approaches to major and minor salivary gland cancer, including reconstructive surgery techniques, and the roles of radiotherapy and heavy ion therapy. Rehabilitation, follow-up, and the management of metastatic disease are also fully discussed. The aim is to equip the reader with the knowledge required to deliver appropriate tailored treatment in each patient, based on tumor characteristics and other pertinent factors. An additional feature is the inclusion of information on advocacy groups and their perspectives. All of the chapters are written by leading specialists in the field. In presenting the most recent advances and innovations in diagnosis and therapy and relating them to individualized treatment, this book will appeal to a wide audience including otorhinolaryngologists, head and neck surgeons, maxillofacial surgeons, radiation oncologists, and other clinicians.

Summary: This book provides a comprehensive update on the latest information and knowledge which emerged from translational and basic science research endeavors, targeting the regeneration of salivary glands. The coverage includes salivary gland growth and development, stem cell therapy, bioengineering of salivary glands, and perspectives on and practical approaches to restoration of secretory function. More specifically, among the individual topics addressed are the various types of stem cell of value for cell replacement therapy, technological advances with respect to 3D printing, gene therapy, organ culture of salivary glands, and surgical aspects of the feasibility and practicality of transplantation. Readers will find helpful practical guidance on functional restorations of damaged salivary glands and stimulating insights into potential future directions in salivary gland regeneration research. The authors are all acknowledged experts from a range of academic and clinical backgrounds. Accordingly, the book will be of interest not only to clinicians, such as general dental practitioners, oral medicine specialists, and surgeons who manage dry mouth patients, but also to biomedical engineers, stem cell researchers, and transplant surgeons.

Contents:
Updates on Salivary Gland Development: Salivary Gland Development
Systems Analysis of Salivary Gland Development and Disease
The Roles of Mucins in Salivary Gland Development and Regeneration. Glandular Damage and Cell Replacement Therapy: Salivary Gland Resident Stem Cells
Adult Stem Cells with Special Emphasis on Mesenchymal Stem Cells
Cellular and Nuclear Reprogramming of Mesenchymal Stem Cells. Bioengineering of Salivary Glands: Current Cell Models for Bioengineering Salivary Glands
3D Organ Culture and Matrix Biology
Clinical Application of 3D Printing Technology in Craniofacial Plastic Surgery and Salivary Gland Regeneration
Functional Salivary Gland Regeneration by Organ Replacement Therapy
Therapeutic Considerations for Functional Salivary Gland Restorations: Regulation of Salivary Secretion
Gene Therapy in Experimental and Clinical Trials
Surgical Approaches to Functional Restoration of Saliva Secretion.

Contents:
Classification of salivary gland neoplasms / Bradley, P.J
Frequency and histopathology by site, major pathologies, symptoms and signs of
Salivary gland neoplasms / Bradley, P.J
Molecular pathology and biomarkers / Ha, P.K, Stenman, G
Evaluation : imaging studies / Kontzialis, M., Aygun, N., Glastonbury, C.M
Evaluation : fine needle aspiration cytology, ultrasound-guided core biopsy and
Open biopsy techniques / Howlett, D., Triantafyllou, A
Nerve monitoring / Guntinas-Lichius, O., Eisele, D.W
Surgery for benign salivary neoplasms / Gillespie, M.B., Iro, H
Recurrent benign salivary gland neoplasms / Witt, R.L., Nicolai, P
Prognostic scoring for malignant salivary gland neoplasms / Vander Poorten V., Guntinas-Lichius, O
Surgery for primary malignant parotid neoplasms / Deschler D.G., Eisele, D.W
Metastatic cancer to the parotid / Clark, J., Wang, S
Surgery for malignant submandibular gland neoplasms / Silver, N.L., Chinn, S.B., Bradley, P.J., Weber, R.S
Surgery for malignant sublingual and minor salivary gland neoplasms / Bradley, P.J., Ferris, R.L
Facial reconstruction and rehabilitation / Guntinas-Lichius, O., Genther, D.J., Byrne, P.J
Management of regional metastases of malignant salivary gland neoplasms / Medina, J., Zbären, P., Bradley, P.J
Indications for salivary gland radiotherapy / Thomson, D.J., Slevin, N.J., Mendenhall, W.M
Chemotherapy and targeted therapy / Sen, M., Prestwich, R
Management of inoperable malignant neoplasms / Kiess, A.P., Quon, H
Management of recurrent malignant salivary neoplasms / Richmon, J.D., Quon, H
Salivary gland neoplasms in children and adolescents / Bradley, P.J., Eisele, D.W
Distant metastases and palliative care / Glazer, T.A., Shuman, A.G
Quality of life after salivary gland surgery / Wax, M.K., Talmi, Y.P
Salivary gland neoplasms: future perspectives / Eisele, D.W., Bradley, P.J.

Contents:
Surgical Anatomy, Embryology, and Physiology of the Salivary Glands / John D Langdon
Diagnostic Imaging of Salivary Gland Pathology / J Michael McCoy, Pradeep K Jacob
Infections of the Salivary Glands
Cysts and Cyst-Like Lesions of the Salivary Glands
Sialolithiasis
Systemic Diseases Affecting the Salivary Glands
Salivary Gland Pathology in Children and Adolescents
Classification, Grading, and Staging of Salivary Gland Tumors / J Michael McCoy, John Sauk
The Molecular Biology of Benign and Malignant Salivary Gland Tumors / Randy Todd
Tumors of the Parotid Gland
Tumors of the Submandibular and Sublingual Glands
Tumors of the Minor Salivary Glands
Radiation Therapy for Salivary Gland Malignancies / Joseph R Kelley, Max Ofori
Systemic Therapy for Salivary Gland Cancer / Janakiraman Subramanian, Lara Kujtan
Non-salivary Tumors of the Salivary Glands
Trauma and Injuries to the Salivary Glands
Miscellaneous Pathologic Processes of the Salivary Glands
Complications of Salivary Gland Surgery / Michael D Turner
Innovations in Salivary Gland Surgery / Mark McGurk, Katherine George.

Contents:
Luminex® multiplex bead suspension arrays for the detection and serotyping of Salmonella spp / Sherry A. Dunbar [and 4 others]
Quantitative proteomic identification of host factors involved in the Salmonella typhimurium infection cycle / Dora Kaloyanova [and 3 others]
Determination of antimicrobial resistance in Salmonella spp / Belgode N. Harish and Godfred A. Menezes
Red-mediated recombineering of Salmonella enterica genomes / Frederik Czarniak and Michael Hensel
A method to introduce an internal tag sequence into a Salmonella chromosomal gene / Weidong Zhao and Stéphane Méresse
Generation and use of site-directed chromosomal cyaA' translational fusions in Salmonella enterica / Francisco Ramos-Morales [and 3 others]
Detection of antimicrobial (poly)peptides with acid urea polyacrylamide gel electrophoresis followed by Western immunoblot / Edith Porter [and 3 others]
Detecting non-typhoid Salmonella in humans by enzyme-linked immunosorbent assays (ELISAs) : practical and epidemiological aspects / Katrin G. Kuhn [and 3 others]
Study of the Stn protein in Salmonella; a regulator of membrane composition and integrity / Masayuki Nakano [and 4 others]
Development of a bacterial nanoparticle vaccine / Carlos Gamazo [and 4 others]
Direct attachment of nanparticle cargo to Salmonella typhimurium membranes designed for combination bacteriotherapy against tumors / Robert Kazmierczak [and 3 others]
Applications of microscopy in Salmonella research / Layla M. Malt [and 3 others]
Live cell imaging of intracellular Salmonella enterica / Alexander Kehl and Michael Hensel
In vitro modeling of gallbladder-associated Salmonella spp. colonization / Geoffrey Gonzalez-Escobedo and John S. Gunn
Salmonella phages and prophages : genomics, taxonomy, and applied aspects / Andrea I. Moreno Switt [and 6 others].

Summary: This book comprehensively covers application of salvage therapy in reuccurrent prostate cancer. Chapters focus on specific issues associated with a range of surgical and oncological management techniques and strategies including hormone therapy, lymphnode dissection, robotic prostatectomy and salvage reirradiation after locoregional failure. Learning objectives, and definitions of keywords are provided to aid the reader develop a thorough understanding of the topic and reinforce the key points covered in each chapter. Salvage Therapy for Prostate Cancer provides a detailed practically applicable guide on how salvage therapy can be utilised in the treatment of prostate cancer. It represents a valuable resource for trainee and practicing urologists, oncologists, and specialist nurses.

Contents:
Systematic Review of Open, Laparoscopic and Robotic Salvage Radical Prostatectomy
Salvage Prostatectomy for Radio-recurrent Prostate Cancer
Salvage Robot-Assisted Radical Prostatectomy for Recurrent Localized Prostate Cancer after Radiation Therapy- Pre-operative Assessment, the contribution of Robotics and Outcomes
Disease Recurrence after Radical Prostatectomy
Salvage Therapy in Prostate Cancer- Predictors of Recurrence
The Role of MRI in Recurrent Prostate Cancer
Clinical Staging/Diagnostic Imaging
Imaging for Salvage Therapy in Recurrent Prostate Cancer
The Role of PET in Salvage Therapy for Prostate Cancer
Salvage Radiotherapy
Salvage Cryotherapy in Prostate Cancer
Salvage Treatment after Focal Therapy
Salvage Re-Irradiation after Locoregional Failure with Primary Radiotherapy for Prostate Cancer
Salvage Brachytherapy- Outcomes from Low and High dose Brachytherapy in Prostate Cancer
Salvage Brachytherapy after Primary Brachytherapy in Recurrent Prostate Cancer
Focal Salvage Therapy for Prostate Cancer Recurrence after Primary Radiotherapy
Salvage Lymph Node Dissection
Salvage Re-irradiation Therapy after Loco-regional Failure for Radiotherapy
Role of Metastasectomy in Prostate Cancer Patients following Primary Treatment
Incontinence of Urine after the Treatment of Prostate Cancer
Erectile Dysfunction in Salvage Prostate Cancer Therapies.

Summary: This is the first book on the genome of Salvia miltiorrhiza, summarizing the research advances in the molecular mapping, whole genome sequencing, chloroplast and mitochondria genomes, epigenetics, transcriptomics and functional genomics of this emerging model plant with great economic and medicinal value. It also describes its distribution, taxonomy and morphology and provides useful information on its cultivation and breeding. Further, it highlights the biosynthetic pathways of tanshinones and phenolic acids - two main classes of bioactive components produced in this plant species - and reviews and discusses the technology of hairy root induction, tissue culture and genetic transformation of S. miltiorrhiza. The book is a valuable resource for students, teachers and researchers in academia and industry interested in medicinal plants and pharmacy.

Contents:
Intro; Preface to the Series; Preface; Contents; Contributors; 1 Salvia miltiorrhiza: An Economically and Academically Important Medicinal Plant; Abstract; 1.1 Introduction; 1.2 Taxonomy; 1.3 Distribution; 1.4 Morphology; 1.5 Propagation; 1.6 Growth Requirements; 1.7 Chemical Constituents; 1.8 Medicinal Significance; 1.9 Academic Significance; 1.10 Conclusion; Acknowledgements; References; 2 Salvia miltiorrhiza Resources, Cultivation, and Breeding; Abstract; 2.1 Introduction; 2.2 Danshen Resources; 2.3 Danshen Distribution and Cultivation; 2.3.1 Wild and Cultivated Distribution 2.3.2 Cultivation Procedures2.3.3 Cultivation-Related Research Findings; 2.4 Danshen Breeding; 2.4.1 System and Bulk Selection; 2.4.2 Cross-breeding; 2.4.3 Polyploidy Breeding; 2.4.4 Space Mutation; 2.5 Perspectives; Acknowledgements; References; 3 Molecular Maps and Mapping of Genes and QTLs of Salvia miltiorrhiza; Abstract; 3.1 Introduction; 3.2 Molecular Linkage Map Construction; 3.2.1 Map Strategy and Mapping Populations; 3.2.2 F1 Genotyping, Data Analysis and Map Construction Method; 3.2.3 Genetic Linkage Map Construction of S. miltiorrhiza 3.2.3.1 The First Linkage Genetic Map and Another Map Based on Integration of Multiple Markers3.2.3.2 The Genomic SSR Linkage Genetic Map; 3.2.3.3 The High-Density Linkage Genetic Map; 3.3 Quantitative Trait Loci Analysis of Important Agronomic Traits in S. miltiorrhiza; 3.3.1 Quantitative Trait Loci (QTL) Mapping Method; 3.3.2 QTL Analysis for Phenolic Acid Content; 3.3.3 QTL Analysis for Root Yield; 3.4 Discussion; Acknowledgements; References; 4 The Genome of Salvia miltiorrhiza; Abstract; 4.1 Introduction; 4.2 The Sequencing and Assembly of S. miltiorrhiza Genome 4.2.1 Sequencing of the S. miltiorrhiza 99-3 Genome (Xu et al. 2016a)4.2.2 Genome Assembly of the S. miltiorrhiza; 4.2.3 Genome Annotation and Repeat Element Analysis; 4.2.4 Genome Family Evolution of S. miltiorrhiza; 4.2.5 Gene Clusters Related to Tanshinone Biosynthesis; 4.3 The Chloroplast Genome of S. miltiorrhiza; 4.4 The Full-Length Transcriptome Based on S. miltiorrhiza Genome; 4.4.1 Full-Length Transcriptome Analysis; 4.4.2 Identification of Alternatively Spliced Isoforms Using Full-Length Transcriptome Data; 4.5 Conclusion; Acknowledgements; References 5 The Chloroplast and Mitochondrial Genomes of Salvia miltiorrhizaAbstract; 5.1 Introduction; 5.2 Transcriptome of S. miltiorrhiza Chloroplasts; 5.3 Methylation of S. miltiorrhiza Plastome; 5.4 Basic Information for S. miltiorrhiza Mitochondrial Genome; 5.5 RNA Editing of S. miltiorrhiza Mitogenome; 5.6 Conclusion and Perspectives; Acknowledgements; References; 6 Salvia miltiorrhiza Epigenetics; Abstract; 6.1 Introduction; 6.2 miRNAs in S. miltiorrhiza; 6.2.1 miRNAs and Development of S. miltiorrhiza; 6.2.2 miRNAs Involved in Signal Transduction

Summary: This second edition of Samii's Essentials in Neurosurgery contains revised and updated versions of chapters from the first edition plus contributions on new topics written by leading neurosurgeons who were trained by Professor Madjid Samii in Hannover, Germany. Almost all fields of neurosurgery are covered. The authors follow the traditional principles of Samii's philosophy in the diagnosis and management of various neurosurgical pathologies, while presenting their own personal experiences. The extensively illustrated texts document clearly how cutting-edge technology in neurosurgery is being applied in new approaches and techniques. This book will greatly assist neurosurgeons, ENT surgeons, neuroradiologists, neurologists, and neurophysiotherapists in their everyday practice.

Contents:
The Virtual Operating Field: How Image Guidance Became Integral to Microneurosurgery
Potential and Limitations of Chronic High-Fr Deep-Brain Stimulation in Parkinson's Disease
Proliferation Behaviour of Meningiomas
Neurotransplantation and the Restoration of Motor Behavior in Parkinson's Disease
Preservation and Restitution of Auditory Function in Neurofibromatosis Type 2
Restoration of Locomotion in Post-traumatic Paraplegics: The Neurosurgeon's Personal View
Spinal Robotics
Endoscope-Assisted Microsurgery
Intraoperative Brain Mapping
Endoscopy and Thermodiskoplasty: A Minimally Invasive Surgical Treatment for Lumbar Pain
Considerations for Experimental Neuromodulation Following Grafting of the Spinal Cord to Skeletal Muscles for Clinical Application
Preoperative Visualization of the Facial Nerve Using Diffusion Tensor Imaging Fibre Tracking in Patients with Large Vestibular Schwannomas
Olfactory Groove Meningiomas: Pitfalls and Surgical Technique
Preservation of the Olfactory Tract in Bifrontal Craniotomy
Treatment of Meningiomas Involving the Optic Nerve Sheath
Surgical Management of Tuberculum Sellae Meningiomas
Sphenoid Wing Meningiomas
Chordomas and Chondrosarcomas
Petroclival Meningiomas Diagnosis, Treatment, and Results
Retrosigmoid Approach to the Posterior and Middle Fossa
The Surgical Management of Trigeminal Schwannomas
Facial Nerve Schwannomas
Vestibular Schwannoma: Current State of the Art
Functional Microsurgery of Vestibular Schwannomas
Surgery of Large and Giant Residual/Recurrent Vestibular Schwannomas
Arachnoid Cysts of the Posterior Fossa
Facial and Cochlear Nerve Function After Surgery of Cerebellopontine Angle Meningiomas
Jugular Foramen Tumors: Diagnosis and Management Endoscopic Transnasal Surgery for Clival Chordoma
Surgery of Cerebellopontine Angle Epidermoids
Approaches to the Orbit: A 360-Degree View
Pituitary Surgery Beyond the Sella
Tumors of the Craniocervical Junction: Overview and Update
Diagnosis and Treatment of Adult Hydrocephalus
Primary Tethered Cord Syndrome
Peripheral Nerve Entrapment Syndromes of the Lower Extremity
Hypoglossal-Facial Nerve Anastomosis
Facial Pain: Diagnosis and Therapy
Epilepsy Surgery
Bypass and Vascular Reconstruction for Anterior Circulation Aneurysms
Bypass and Vascular Reconstruction for Posterior Circulation Aneurysms
Full-Endoscopic Lumbar and Cervical Surgery for Disc Herniation
Syringomyelia and Syringobulbia
Total Lumbar Facet Replacement: Indication, Technique, and 3- and 4-Year Results
Mini-open Transforaminal Lumbar Interbody Fusion for Degenerative Diseases.

Contents:
Coma, head trauma, and spinal cord injury / Galen V. Henderson and Matthew B. Bevers
Epilepsy / Rani A. Sarkis and Barbara Dworetzky
Dizziness / Gregory T. Whitman and Robert W. Baloh
Back and neck pain / Allan H. Ropper
Sleep disorders / Milena Pavlova
Cancer neurology / Eudocia Quant Lee and Patrick Y. Wen
Multiple sclerosis and related disorders / Maria K. Houtchens and James M. Stankiewicz
Autoimmune disorders / Ivana Vodopivec and Henrikas Vaitkevicius
Neuromuscular junction disorders and myopathies / Anthony A. Amato and Mohammed Kian Salajegheh
Motor neuronopathies and peripheral neuropathies / Mohammed Kian Salajegheh and Anthony A. Amato
Chronic pain / Daniel D. Vardeh
Headache and facial pain / Paul B. Rizzoli and Elizabeth Loder
Stroke and cerebrovascular disorders / Henrikas Vaitkevicius and Steven K. Feske
Movement disorders / Jordan D. Paulson and Lewis R. Sudarsky
Behavioral and cognitive neurology / Seth A. Gale and Kirk Daffner
Management of neurologic disorders in resource-limited settings / Aaron L. Berkowitz
Neuroophthalmology / Robert M. Mallery and Sashank Prasad
Toxic and metabolic disorders / Shamik Bhattacharyya and Martin A. Samuels
Infectious diseases / Jennifer Lyons and Tracey A. Cho.

Summary: "The physical exam can either determine disease or confirm good health. When a patient presents to her physician with a set of symptoms, the physical exam and patient history can identify the cause and serve as a guide for subsequent diagnostic testing. It is a key building block in the practice of medicine, yet students and residents have difficulty determining what information is relevant and how it applies to the patient"--Provided by publisher.

Contents:
Introduction
The interview
The history
The case record
General apperance
The vital signs
Integument
Lymph nodes
The head
The eye
The ear
The nose
The oropharynx
The neck
The breast
The chest
The heart
Arteries
Veins
The abdomen
Male genitalia
Female genitalia
The rectum
The extremities
The musculoskeletal system
The neurologic examination
Clinical reasoning
Some bedside laboratory tricks
Annotated bibliography.

Summary: The purpose of this book is to define and demonstrate how a multidisciplinary team can be organized, integrated, and utilized in the care of sarcoma patients. Real world experiences related by multiple sarcoma specialists working as members of a multidisciplinary team along with specific case examples highlighting sarcomas of bone and soft tissue in children and adults are presented in a framework geared toward practicing oncologists and surgeons in order to foster the creation and development of care teams for sarcoma patients. It is explained how a truly multidisciplinary approach, with "one stop shopping," offers better standardization and delivery of care, streamlines patient education, facilitates discussions and decision making, and provides comprehensive support throughout the treatment process. All aspects of treatment are covered, from first-line treatments for different tumor types through to salvage therapy and the development of novel investigational agents. This book will be of benefit to all members of the medical community who have a role to play in the care of these complex patients, including therapists, nurses, mid-level practitioners, primary care doctors, and subspecialists.

Summary: This book aims to compile an expert text on the multidisciplinary approach to treating sarcoma at a sarcoma centre. Separate chapters and sections highlight the specialist diagnostic and therapeutic approaches employed in treating bone and soft tissue sarcoma. This comprehensive book covers sarcoma and its management across specialties. It brings together the experience of the editor at a major centre for sarcoma management in Australia along with chapter contributions from various experts on the topic. The real-life, pragmatic approach is a distillation of the evidence and intends to make much of what is written translatable. This book serves as a reference for managing this tumour type and as an indispensable guide for daily use across the spectrum of providers.

Contents:
Introduction to sarcomas- Biology and behavior of sarcomas
The role and benefits of multidisciplinary-based sarcoma treatment centres
The investigation of sarcomas
The histopathological examination of sarcomas
The role of chemotherapy in management of sarcomas
The role of radiotherapy in management of sarcomas
The role of surgery in management of sarcomas
Plastic and reconstructive surgery in management of sarcomas
The management of metastatic sarcoma
The principles of management of sarcoma for adolescent and young adults
Quality of life after surgery for extremity sarcoma.

Contents:
Intro
Contents
1: Epidemiology of Bone and Soft Tissue Sarcomas
1.1 Introduction
1.2 Descriptive Epidemiology
1.2.1 Osteosarcoma
1.2.2 Ewing Sarcoma
1.2.3 Rhabdomyosarcoma (RMS)
1.2.4 Non-rhabdomyosarcoma Soft Tissue Sarcoma (NRSTS)
1.3 Environmental (Non-genetic) Risk Factors
1.3.1 Osteosarcoma
1.3.1.1 Growth and Development
1.3.1.2 Exogenous Exposures
1.3.2 Ewing Sarcoma
1.3.3 RMS
1.3.4 NRSTS
1.4 Germline Genetic Risk Factors
1.4.1 Osteosarcoma
1.4.2 Ewing Sarcoma
1.4.3 RMS
1.4.4 NRSTS
1.5 Conclusion 2.3.1 Pathology
2.3.2 Biology
2.4 Non-rhabdomyosarcoma Soft Tissue Sarcomas
2.4.1 Alveolar Soft Part Sarcoma
2.4.1.1 Pathology
2.4.1.2 Biology
2.4.2 Clear Cell Sarcoma of Soft Tissue
2.4.2.1 Pathology
2.4.2.2 Biology
2.4.3 Desmoid Tumor
2.4.3.1 Pathology
2.4.3.2 Biology
2.4.4 Desmoplastic Small Round Cell Tumor
2.4.4.1 Pathology
2.4.4.2 Biology
2.4.5 Malignant Peripheral Nerve Sheath Tumor
2.4.5.1 Pathology
2.4.5.2 Biology
2.4.6 Synovial Sarcoma
2.4.6.1 Pathology
2.4.6.2 Biology
2.4.7 Malignant Rhabdoid Tumor 2.4.7.1 Pathology
2.4.7.2 Biology
2.4.8 NTRK-Fusion Sarcomas
2.4.8.1 Pathology
2.4.8.2 Biology
References
3: Staging and Imaging of Sarcoma
3.1 Staging of RMS and NRSTS
3.2 Staging of Nonrhabdomyosarcomatous Soft Tissue Tumors (NRSTS)
3.3 Staging of Bone Sarcomas
3.4 Imaging and Staging Procedures
References
4: Multi-institutional Trials for Patients with Rhabdomyosarcoma: Lessons from North American Studies from 1967 Through 1997
4.1 Introduction
4.2 The First 30 Years, 1970-2000
4.2.1 The IRS Era, 1972-1997
References 5: Treatment of Rhabdomyosarcoma
5.1 Introduction
5.2 Initial Evaluation
5.3 Treatment Assignment
5.4 Treatment
5.4.1 North American Perspective
5.4.2 European Perspective
5.5 Future Directions
References
6: Current Approaches to Therapy: Soft Tissue Sarcomas Other than Rhabdomyosarcoma in Children and Adolescents
6.1 Introduction
6.2 Local Therapy
6.2.1 Surgery
6.2.2 Radiotherapy
6.3 Conventional Chemotherapy
6.4 Specific Therapy for Diseases
6.4.1 Synovial Sarcoma 6.4.2 Other "Adult-Type" Sarcomas (Fibrosarcoma, Liposarcoma, Mesenchymal Chondrosarcoma, PECOMA, Leiomyosarcoma, Epithelioid Sarcoma, Clear Cell Sarcoma, Angiosarcoma, Undifferentiated Sarcoma).

Summary: "Maintaining adequate muscle mass is crucial to healthy aging. Numerous diseases as well as deterioration of motor nerves and muscle repair mechanisms cause risks to developing sarcopenia. Sedentary lifestyles coupled with excess caloric intake among senior citizens compound the problem by creating a condition of limited muscle strength overwhelmed with body weight. This book presents biochemical, nutritional, and metabolic implications related to sarcopenia. It provides information on mechanisms regulating age-related loss of muscle mass and function as well as nutritional anti-aging strategies to fight against atrophy and support healthy aging"-- Provided by publisher.

Contents:
Definitions of sarcopenia / Heike Bischoff-Ferrari and Bess Dawson-Hughes
Models of accelerated sarcopenia / Andrew S. Layne, Lisa M. Roberts and Thomas W. Buford
Sarcopenia in physical frailty / Maturin Tabue-Teguo, Emanuele Marzetti, Riccardo Calvani, Bruno Vellas, Matteo Cesari
The role of imaging techniques in the diagnosis of sarcopenia / Thiago Gonzalez Barbosa-Silva and Carla Prado
Nutrient sensing and mTORC1 regulation in sarcopenia / Ted G. Graber and Blake B. Rasmussen
Different adaptation of ubiquitin-proteasome and lysosome-autophagy signaling in sarcopenic muscle / Kunihiro Sakuma, Hidetaka Wakabayashi
Myokines in aging muscle / Katie Brown, Aaron Persinger, and Melissa Puppa
The contribution of satellite cells to skeletal muscle aging / Christopher Fry
Muscle stem cell microenvironment in sarcopenia / Neia Naldaiz-Gastesi and Ander Izeta
Sarcopenia and oxidative stress : from the bench to therapeutical strategies / Coralie Arc-Chagnaud, Allan F. Pagano, Thomas Brioche
Muscle protein turnover and sarcopenia in the elderly : the effects of nutrition / Paolo Tessari
The relationship between muscle mitochondrial turnover and sarcopenia / Heather N. Carter, Nashwa Cheema and David A. Hood
Skeletal muscle fat infiltration with aging : an important factor of sarcopenia / Allan F. Pagano, Coralie Arc-Chagnaud, Thomas Brioche, Angèle Chopard, Guillaume Py
Nutritional modulation of mitochondrial-associated death signaling in sarcopenia / Stephen E. Alway
Beneficial effects and limitations of strategies (nutritional or other) to limit muscle wasting due to normal aging / Dominique Meynial-Denis
Declines in whole muscle function with aging : the role of age-related alterations in contractile properties of single skeletal muscle fibres / Nicole Mazara and Geoffrey A. Power
Sarcopenic dysphagia, presbyphagia and rehabilitation nutrition / Hidetaka Wakabayashi and Kunihiro Sakuma
Wasting and cachexia in chronic kidney disease / Giacomo Garibotto, Daniela Picciotto, Daniela Verzola
Sarcopenia and Parkinson's disease : molecular mechanisms and clinical management / Manlio Vinciguerra
Sarcopenic obesity in the elderly / Michael Tieland, Inez Trouwborst, Amely Verreijen, Robert Memelink and Peter J.M. Weijs
Sum up and future research / Dominique Meynial-Denis.

Summary: This book offers a concise and updated guide for all readers (physicians and non-physicians) interested in gaining a comprehensive and precise understanding of sarcopenia. Over the last several years, sarcopenia has increasingly developed from being a concept known only in research settings to one that is commonly explored in journals and scientific meetings for various disciplines, such as geriatrics, rheumatology and rehabilitation medicine. Thus, all domains of sarcopenia, from molecular aspects to clinical management, represent highly active areas of research and clinical practice for health professionals in a variety of fields, including geriatric medicine, nutrition, and epidemiology. Despite being a relatively new concept in medicine, sarcopenia is increasingly being recognized as an important determinant of other health conditions, including mortality and disability. This book, written by experts from around the globe, covers several core aspects of sarcopenia management, from molecular mechanisms to genetics, epidemiology, diagnosis and finally treatment, including the clinical impact of sarcopenia as a risk factor, the known genetic and molecular aspects that can aid in predicting sarcopenia, and selected treatment and therapy concepts, including indications for nutrition and physical exercise. Sharing data from the latest studies, it will be of considerable interest not only for geriatricians, but also for a wide range of other readers.

Contents:
Chapter 1) Epidemiology of Sarcopenia
Chapter 2) Definitions of Sarcopenia Across the World
Chapter 3) Consequences of Sarcopenia in Older People: The Epidemiological Evidence
Chapter 4) Emerging Markers for Sarcopenia
Chapter 5) Screening for Sarcopenia
Chapter 6) Radiological Evaluation of Muscle Mass
Chapter 7) Physical Performance and Muscle Strength Tests: Pros and Cons
Chapter 8) Is Sarcopenia a Condition, a Disorder, a Disease, or a True Geriatric Syndrome?
Chapter 9) Sarcopenia in Other Settings: Primary Care, Cardiovascular Disease, Surgery
Chapter 10) Acute Sarcopenia: Definition and Actual Issues
Chapter 11) Sarcopenic Obesity
Chapter 12) The Role of Physical Activity in Sarcopenia
Chapter 13) Nutritional Approaches for Sarcopenia
Chapter 14) The Future of Drugs in Sarcopenia
Chapter 15) Sarcopenia and Covid-19: A New Entity?.

Summary: SARS reference is a medical textbook that provides a comprehensive and up-to-date overview of severe acute respiratory syndrome (SARS).

Summary: Satellite remote sensing presents an amazing opportunity to inform biodiversity conservation by inexpensively gathering repeated monitoring information for vast areas of the Earth. However, these observations first need processing and interpretation if they are to inform conservation action. Through a series of case studies, this book presents detailed examples of the application of satellite remote sensing, covering both aquatic and terrestrial ecosystems, to conservation. The authors describe how collaboration between the remote sensing and conservation communities makes satellite data functional for operational conservation, and provide concrete examples of the lessons learned in addition to the scientific details. The editors, one at NASA and the other at a conservation NGO, have brought together leading researchers in conservation remote sensing to share their experiences from project development through to application, and emphasise the human side of these projects.

Contents:
A brief introduction to conservation and conservation remote sensing / Graeme M. Buchanan and Allison K. Leidner
Introduction to remote sensing for conservation practitioners / Andreas Brink, Cindy Schmidt and Zoltan Szantoi
Satellite remote sensing for the conservation of East Asia's coastal wetlands / Nicholas J. Murray
Global forest maps in support of conservation monitoring / Samuel Jantz, Lilian Pintea, Janet Nackoney and Matthew C. Hansen
Wildfire monitoring with satellite remote sensing in support to conservation / Ilaria Palumbo, Abdoulkarim Samna, Marco Clerici, and Antoine Royer
Ecosystem Functioning Observations for assessing conservation in the Doñana National Park, Spain / Paula Escribano and Nestor Fernandez
Predicting mule deer harvest in real-time: Integrating satellite remote-sensing measures of forage quality and climate in Idaho, United States / Mark Hebblewhite, Mark Hurley, Paul Lukacs and Josh Nowak
Lessons learned from WhaleWatch: a tool using satellite data to provide near real-time predictions of whale occurrence / Helen Bailey, Elliott Hazen, Bruce Mate, Steven J. Bograd, Ladd Irvine, Daniel M. Palacios, Karin A. Forney, Evan Howell, Aimee Hoover, Lynn DeWitt, Jessica Wingfield and Monica DeAngelis
The evolution of remote sensing applications vital to effective biodiversity conservation and sustainable development / Karyn Tabor and Jennifer Hewson
Operational concervation remote sensing: common themes, lessons learned, and future prospects / Allison K. Leidner and Graeme M. Buchanan.

Summary: "The Savvy Ally: A Guide for Becoming a Skilled LGBTQ+ Advocate is an enjoyable, humorous, encouraging, easy to understand guidebook for being an ally to LGBTQ+ communities"-- Provided by publisher. "Bursting with passion and humor, The Savvy Ally: A Guide for Becoming a Skilled LGBTQ+ Advocate is a treasure trove for allies to the LGBTQ+ communities. This fully revised second edition includes: the most current information on identities and LGBTQ+ language; tips for respectfully sharing, gathering, and using pronouns; LGBTQ+ etiquette, including common language bloopers to avoid; tools for navigating difficult conversations; best practices for creating LGBTQ+ inclusive spaces; appropriate actions to take after messing up; techniques for self-care and sustainable allyship. The Savvy Ally is a vital resource for teachers, mental health professionals, healthcare providers, college professors, faith leaders, family members, and friends who want to support and advocate for the LGBTQ+ people in their lives and help make the world a safer, more inclusive place. This informative, encouraging, and easy-to-understand guidebook will jump-start even the most tentative ally"--Back cover

Contents:
Getting started
Part I: Becoming knowledgeable allies
Caution: identities being defined!
Coming out as LGBTQ+
Orientations, identities, behaviors--oh my!
Part II: Building skills for having respectful conversations
Pronouns: sharing, gathering, and using
LGBTQ+ etiquette tips, common bloopers, and outdated terms
Gaydar and other problematic assumptions
Good talk: the art of having useful conversations
Part III: Taking action to create more inclusive spaces. Straight pride parades and special snowflakes: addressing common questions
Duct tape patch-up jobs and big fixes
Creating LGBTQ+ inclusive spaces in different settings
Taking it to the streets
Now what? Questions from allies in the real world
Part IV: Allying responsibly
Messing up properly
Backlash against allies
Sustainability

Summary: "We spend so much of our lives talking to each other, but how often are we simply running on automatic, relying on old habits and hoping for the best? Are we able to truly hear others and speak our mind in a clear and kind way, without needing to get defensive or go on the attack? In this groundbreaking synthesis of mindfulness, somatics, and nonviolent communication, Oren Jay Sofer offers simply yet powerful practices to develop healthy, effective, and satisfying ways of communicating. The techniques in "Say what you mean" will help you to: Feel confidnet during conversation ; Stay focused on what really matters in an interaction ; Listen for the authentic concerns behind someone's words ; Reduce anxiety before before and during difficult conversations ; Find nourishment in day-to-day interactions

Contents:
The first step: lead with presence. The center of our lives
The power of mindfulness
Relational awareness
The second step: Come from curiosity and care. The blame game
Where are you coming from?
Don't let the call drop
The third step: Focus on what matters. Getting down to what matters
Emotional agility
Enhancing empathy and inner resilience
How to raise an issue without starting a fight
If you want something, ask for it
Bringing it all together. The flow of dialogue
Running the rapids
Conclusion: charting your course.

Contents:
SBA type questions: Antenatal care.- Maternal medical disorders
Fetal medicine
Labour and delivery.- Postpartum issues.- Early Pregnancy care.- Gynaecological problems.- Subfertility and endocrinology.- Sexual and reproductive health.- Gynaecological oncology.- Urogynecology and pelvic floor problems.- Core surgical skills and postoperative care.- Surgical procedures
Clinical governance Single best answers and explanations: Antenatal care.- Maternal medical disorders
Fetal medicine
Labour and delivery.- Postpartum issues.- Early Pregnancy care.- Gynaecological problems.- Subfertility and endocrinology.- Sexual and reproductive health.- Gynaecological oncology.- Urogynecology and pelvic floor problems.- Core surgical skills and postoperative care.- Surgical procedures
Clinical governance .

Summary: "The Part 1 or written MCQ paper is often seen as a poor relation to the more intense clinical and viva preparation needed for the Part 2 exam. The belief is that most candidates usually pass the part 1 without too many difficulties. Occasionally a candidate will have to re sit if they fall a bit short of the pass mark but next time it should be plain sailing getting through"-- Provided by publisher.

Summary: "SCAI Interventional Cardiology Board Review provides a concise overview of the field of interventional cardiology in order to serve as board exam preparation for those in training and those who need to recertify. It is written specifically for this audience and can also serve as a basis for in-depth training by nurses, technicians, physician extenders and general cardiologists. Coverage will include all topics included on the exam and chapters will be written by authors who are also"--Provided by publisher

Contents:
I: Basic science and pharmacology
Arterial disease
atherosclerosis
Restenosis
Platelet
inhibitor agents
Anticoagulant and fibrinolytic agents for NSTE-ACS, PCI, and STEMI
Vasoactive and antiarrhythmic drugs in the catheterization laboratory
II: Fundamentals of interventions
Fundamentals of X-ray imaging, radiation safety, and contrast media
Coronary hemodynamics: pressure and flow
Intravascular ultrasound, optical coherence tomography, and near-infrared spectroscopy
Vulnerable plaque imaging
Hemodynamics for interventional cardiologists
Coronary angiography for PCI
Introduction to statistics in clinical research for interventional cardiology
III: Equipment
Equipment selection for coronary interventions
Niche devices: atherectomy, cutting and scoring balloons, and laser
IV: Stable and acute coronary syndrome PCI
Coronary stents
^Elective percutaneous coronary intervention for stable coronary artery disease and silent myocardial ischemia
Acute coronary syndromes
STEMI intervention: emphasis on guidelines
High-risk percutaneous coronary intervention, cardiogenic shock, and acute mechanical circulatory support devices
V: Higher-risk PCI and complex angiographic subsets
Multivessel percutaneous coronary interventions
Bifurcation lesions and intervention
Small vessel and diffuse disease
Left mainstem intervention
Bypass graft intervention and embolic protection
Complications of coronary intervention
Chronic total occlusion percutaneous coronary intervention
VI: Vascular access and hemostasis
Vascular access: radial and femoral approaches
Vascular access site management (Closure devices and complications)
VII: Women, prevention, and guidelines
Women and percutaneous interventions
Primary and secondary coronary prevention
^PCI guidelines for interventional cardiology boards
VIII: Peripheral vascular disease and interventions
Thoracic aortic, abdominal aortic, and lower extremity interventions
Carotid and cerebrovascular/acute stroke intervention
Atherosclerotic renal artery disease
Deep venous thrombosis
IX: Structural heart disease and interventions
Imaging for structural heart disease
Atrial septal defect and patent foramen ovale
Left atrial appendage closure
Mitral valvuloplasty and percutaneous mitral valve repair
Transcatheter Aortic Valve Replacement
Hypertrophic cardiomyopathy
Paravalvular leaks
Pericardial disease interventions
Interventional procedures in adult congenital heart disease

Summary: "From one of the most influential scientists of our time, a dazzling exploration of the hidden laws that govern the life cycle of everything from plants and animals to the cities we live in. The former head of the Sante Fe Institute, visionary physicist Geoffrey West is a pioneer in the field of complexity science, the science of emergent systems and networks. The term "complexity" can be misleading, however, because what makes West's discoveries so beautiful is that he has found an underlying simplicity that unites the seemingly complex and diverse phenomena of living systems, including our bodies, our cities and our businesses. Fascinated by issues of aging and mortality, West applied the rigor of a physicist to the biological question of why we live as long as we do and no longer. The result was astonishing, and changed science, creating a new understanding of energy use and metabolism: West found that despite the riotous diversity in the sizes of mammals, they are all, to a large degree, scaled versions of each other. If you know the size of a mammal, you can use scaling laws to learn everything from how much food it eats per day, what its heart-rate is, how long it will take to mature, its lifespan, and so on. Furthermore, the efficiency of the mammal's circulatory systems scales up precisely based on weight: if you compare a mouse, a human and an elephant on a logarithmic graph, you find with every doubling of average weight, a species gets 25% more efficient--and lives 25% longer. This speaks to everything from how long we can expect to live to how many hours of sleep we need. Fundamentally, he has proven, the issue has to do with the fractal geometry of the networks that supply energy and remove waste from the organism's body"-- Provided by publisher.

Contents:
The big picture
The measure of all things: an introduction to scaling
The simplicity, unity, and complexity of life
The fourth dimension of life: growth, aging, and death
From the Anthropocene to the Urbanocene: a planet dominated by cities
Prelude to a science of cities
Toward a science of cities
Consequences and predictions: from mobility and the pace of life to social connectivity, diversity, metabolism, and growth
Toward a science of companies
The vision of a grand unified theory of sustainability.

Summary: In this guide, Harnish and his co-authors share practical tools and techniques to help entrepreneurs grow an industry -- dominating business without it killing them -- and actually have fun. Many growth company leaders reach a point where they actually dread adding another customer, employee, or location. It feels like they are just adding more weight to an ever-heavier anchor they are dragging through the sand. To make matters worse, the increased revenues have not turned into more profitability, so at some point they wonder if the journey is worth the effort. This book focuses on the four major decisions every company must get right: People, Strategy, Execution and Cash. The book includes a series of One-Page tools including the One-Page Strategic Plan and the Rockefeller Habits Execution Checklist, which more than 40,000 firms around the globe have used to scale their companies successfully.

Contents:
The overview: People, strategy, execution, cash
The barriers: Leadership, infrastructure, and marketing
The leaders: The FACe and the PACe of the company
The team: Attracting and hiring
The managers (coaches): Keeping and growing (educating) the team
The core: Values, purpose, and competencies
The 7 strata of strategy: The framework for dominating your industry
The one-page strategic plan: The tool for strategic planning
The priority: Focus, finish lines, and fun
The data: Powering prediction
The meeting rhythm: The heartbeat of the organization
The cash: Accelerating cash flow
The accounting: Driving profitability
The power of one: 7 key financial levers
Next steps: 5 things to do now.

Contents:
Scaphoid Anatomy
Non-operative Management of Non-displaced Acute Scaphoid Fracture
Acute Scaphoid Fracture Management: Dorsal Approach
Acute Scaphoid Fractures: Volar Approach
Arthroscopic-Assisted Management of Acute Scaphoid Fractures
Treatment of Acute Pediatric Scaphoid Waist Fractures
Scaphoid Nonunion: Surgical Fixation Without Bone Graft
Scaphoid Non-union Open Treatment with Distal Radius Bone Graft via Mini Dorsal Approach
Scaphoid Nonunion: Surgical Fixation with Local Non-vascularized Bone Graft (Open)
Scaphoid Non-Union Treated with Iliac Crest Structural Autograft
The Hybrid Russe Graft for the Treatment of Scaphoid Nonunion
Arthroscopic Grafting and Scapholunate Pinning for Scaphoid Proximal Pole Nonunion
1,2 ICSRA for the Management of Proximal Pole Scaphoid Nonunion
Dorsal Capsular-Based Vascularized Distal Radius Graft for Scaphoid Nonunion
Scaphoid Nonunion: Surgical Fixation with Vascularized Bone Grafts-Volar Pedicle
Scaphoid Nonunion: Surgical Fixation with Vascularized Bone Graft-Free Medial Femoral Condyle Graft
Pediatric Scaphoid Nonunion
Partial Scaphoidectomy for Unsalvageable Scaphoid Nonunion
Reconstruction of the Unsalvageable Proximal Pole in Scaphoid Nonunions Utilizing Rib Osteochondral Autograft
Recalcitrant Proximal Pole Scaphoid Nonunion
Unsalvageable Scaphoid Nonunion: Implant Arthroplasty
Scaphoid Nonunion Advanced Collapse: Denervation
Scaphoid Nonunion Advanced Collapse: Arthroscopic Debridement/Radial Styloidectomy
Scaphoid Nonunion Advanced Collapse: Capitolunate Arthrodesis
Scaphoid Nonunion Advanced Collapse: Scaphoid Excision and 4-Corner Arthrodesis
PRC for Scaphoid Nonunion Advanced Collapse Wrist
Index.

Contents:
1. A historical perspective on scar management
2. The global impact of scars
3. Medical conditions associated with scarring and fibrosis
4. Scars and scar management: ethical considerations
5. Scar histopathology and morphologic classification
6. The cellular and molecular basis of scarring: the paradigm of hypertrophic scarring after thermal injury
7. The biomechanics of scar formation
8. An approach to scar mitigation
9. Optimizing wound healing and scar formation
10. Medical managment of scars
11. Neurobiology of scars: managing pain and itch
12. Surgical scar revision
13. Lasers and light devices in scar management
14. Laser-assisted delivery of therapeutic agents
15. Fat grafting for scar treatment
16. Multimodal scar management
17. Atrophic scar management
18. Scar management in skin of color
19. Rehabilitative burn scar management
20. Scar camouflage
21. Medical tattooing
22. A pediatric perspective
23. A perspective from military medicine
24. Recovery and reintegration after burn injury
25. Integrating scar management into clinical practice
26. Scar treatment, restoration, and prevention- beyond the horizon?
27. Fetal wound healing
28. Clinical scar research: quantitative and qualitative assessment of hypertrophic burn scars.

Summary: "This textbook is intended to be used in courses on medical microbiology or infectious diseases for medical students, allied health professionals, graduate students, or advanced undergraduates. Because the purpose of this book is to develop a conceptual framework for understanding infection, it highlights certain agents and diseases of special biological or clinical importance and does not attempt to describe the microbial world in an exhaustive fashion"-- Provided by publisher.

Contents:
Hemolymphatic Tissue. Embryonic and Fetal Hematopoiesis / Kelli L Boyd, Brad Bolon
Stem Cell Biology / Dori L Borjesson, Jed A Overmann
Structure of the Bone Marrow / Nicole I Stacy, John W Harvey
The Hematopoietic System / Bruce D Car, Davis M Seelig
Vasculogenesis and Endothelial Cell Production / Jong Hyuk Kim
Cluster of Differentiation (CD) Antigens / Melinda J Wilkerson, Nora L Springer
Major Histocompatibility Complex Antigens / Paul R Hess
Lymphocyte Biology and Functions / Ian Tizard
Structure and Function of Primary and Secondary Lymphoid Tissue / Cleverson D Souza, Meredeth McEntire, VE Ted Valli, Robert M Jacobs
Hematotoxicity. Design and Methods of Nonclinical Hematotoxicity Studies / William J Reagan, Armando R Irizarry Rovira
Interpretation of Hematologic Data in Nonclinical Studies / Jeffrey McCartney
Nonclinical Evaluation of Compound-Related Cytopenias / Laurie G O'Rourke
Nonclinical Evaluation of Compound-Related Alterations in Hemostasis / F Poitout-Belissent
Preclinical Evaluation of Immunotoxicity / Kristin L Henson
Blood and Bone Marrow Toxicity Induced by Drugs, Heavy Metals, Chemicals, and Toxic Plants / Douglas J Weiss
Acute Myelotoxicity and Myelitis in Domestic and Laboratory Animals / Adam D Aulbach, Douglas J Weiss
Chronic Inflammation and Secondary Myelofibrosis in Domestic and Laboratory Animals / Adam D Aulbach, Douglas J Weiss
Infectious Injury to Bone Marrow / K Jane Wardrop
Erythrocytes. Erythropoiesis / Christine Swardson Olver
Erythrocyte Structure and Function / Christine Swardson Olver
Erythrocyte Biochemistry / John W Harvey
Erythrokinetics and Erythrocyte Destruction / Andrea Pires Dos Santos, John A Christian
Reticulocyte and Heinz Body Staining and Enumeration / Harold Tvedten, Andreas Moritz
Erythrocyte Morphology / Anne M Barger
Classification and Laboratory Evaluation of Anemia / Harold Tvedten
Erythrocytosis / John F Randolph, Mark E Peterson, Erica Behling-Kelly
Iron and Copper Deficiencies, and Disorders of Iron Metabolism / Lauren B Radakovich, Christine Swardson Olver
The Porphyrias-Disorders of Defective Heme Synthesis / Andrea A Bohn
Hereditary Erythroenzymopathies / Urs Giger
Erythrocyte Membrane Defects / Mutsumi Inaba, Joanne B Messick
Congenital Dyserythropoiesis / Douglas J Weiss
Anemia Associated with Oxidative Injury / Erica Behling-Kelly, Ashleigh Newman
Anemia Caused by Rickettsia, Mycoplasma, and Protozoa / Susan Fielder, Robin W Allison, James H Meinkoth
Anemia Associated with Bacterial and Viral Infections / George M Barrington, Debra C Sellon
Immune-Mediated Anemia in the Dog / Jillian M Haines, Andrew Mackin, Michael J Day
Immune-Mediated Anemia in the Cat / Ashleigh Newman, Tracy Stokol
Immune-Mediated Anemia in Ruminants and Horses / Jenifer R Gold
Precursor-Targeted Immune-Mediated Anemia and Pure Red Cell Aplasia in Dogs and Cats / Cynthia A Lucidi
Anemia of Inflammatory, Neoplastic, Renal, and Endocrine Diseases / Agata K Grzelak, Michael M Fry
Aplastic Anemia / Jennifer L Brazzell, Douglas J Weiss
Leukocytes. Granulopoiesis / M Judith Radin, Maxey L Wellman
Neutrophil Structure and Biochemistry / Claire B Andreasen
Neutrophil Function and Response / Dana N Levine, Claire B Andreasen
Neutrophil Function Disorders / Stefano Comazzi, Luca Aresu, Douglas J Weiss
Clinical Evaluation of Neutrophil Function / Stefano Comazzi
Eosinophils and Their Disorders / Karen M Young, Elizabeth A Layne
Basophils, Mast Cells, and Their Disorders / Brandy C Kastl, Lisa M Pohlman
Monocytes, Macrophages, and Dendritic Cell Production / Cleverson D Souza, Douglas J Weiss
Monocytes and Macrophages and Their Disorders / Cleverson D Souza, Meaghan V Eren
Lymphocyte Ontogeny and Lymphopoiesis / Amy L Warren, Robin M Yates
Structure, Function, and Disorders of Lymphoid Tissue / Amy L Warren, Robin M Yates
Systemic Lupus Erythematosus / Luc Chabanne
Feline Immunodeficiency Virus / Margaret J Hosie, Hans Lutz
T Cell, Immunoglobulin, and Complement Immunodeficiency Disorders / Peter J Felsburg
Severe Combined Immunodeficiencies / Steven E Suter
Lymphadenopathy Not Caused by Lymphoma / Harold Tvedten
Hematologic Neoplasia. Cell-Cycle Control in Hematopoietic Cells / Jaime F Modiano, Catherine A St Hill
Epidemiology of Hematopoietic Neoplasia / Michelle G Ritt
Genetics of Hematopoietic Neoplasia / Diana Giannuzzi, Jaime F Modiano, Matthew Breen
Transforming Retroviruses / Mary Jo Burkhard
Cytochemical Staining and Immunocytochemistry / Rose E Raskin, Kelly Santangelo, Klaudia Polak
Determination of Clonality / Yuko Goto-Koshino, Hajime Tsujimoto
Immunophenotyping / Austin K Viall
Flow Cytometry in Hematologic Neoplasia / Jaime L Tarigo, Davis M Seelig, Anne C Avery
Classification and General Features of Lymphoma and Leukemia / Barbara C Rütgen, Jennifer Bouschor
Myeloproliferative Neoplasms / Eric J Fish
Myelodysplastic Syndromes / Douglas J Weiss, Rance K Sellon
Acute Myeloid Leukemia / Tracy Stokol
B-Cell Tumors / Luca Aresu, Stefano Comazzi, Laura Marconato, Francesco Bertoni
Plasma Cell Tumors / Antonella Borgatti
Hodgkin and Hodgkin-Like Lymphoma / Daniel A Heinrich, Erin N Burton
T-Cell Tumors / Nariman Deravi, Stefan Keller, Dorothee Bienzle
Mast Cell Neoplasia / Melinda S Camus
Histiocytic Proliferative Diseases of Dogs and Cats / Peter F Moore
Platelets. Thrombopoiesis / Mary K Boudreaux, Pete W Christopherson
Platelet Structure / Mary K Boudreaux, Pete W Christopherson
Platelet Signal Transduction and Activation Response / Pete W Christopherson, Mary K Boudreaux
Platelet Kinetics and Laboratory Evaluation of Thrombocytopenia / Adi Wasserkrug-Naor
Evaluation of Platelet Function / Pete W Christopherson, Marjory B Brooks
Immune Thrombocytopenia / Dana N LeVine, Marjory B Brooks
Nonimmune-Mediated Thrombocytopenia / Julie Allen
Thrombocytosis and Essential Thrombocythemia / Julie Allen, Tracy Stokol
von Willebrand Disease / Marjory B Brooks, James L Catalfamo
Inherited Platelet Disorders / Mary K Boudreaux, Pete W Christopherson
Acquired Platelet Dysfunction / Benjamin M Brainard
Treatment of Disorders of Platelet Number and Function / Mary Beth Callan
Hemostasis. Overview of Hemostasis / Maureen A McMichael
Laboratory Testing of Coagulation Disorders / Marjory B Brooks
Acquired Coagulopathies / Marjory B Brooks, Armelle De Laforcade
Hereditary Coagulopathies / Marjory B Brooks
Thrombotic Disorders / Erica Behling-Kelly, Robert Goggs
Disseminated Intravascular Coagulation / Tracy Stokol
Vascular Diseases / Sean P McDonough
Treatment of Hemostatic Defects / Robert Goggs, Alex M Lynch
Avian Hemostasis / Karen E Russell, J Jill Heatley
Transfusion Medicine. Erythrocyte Antigens and Blood Groups / Marie-Claude Blais, Maria Cecilia T Penedo
Granulocyte and Platelet Antigens / Jennifer S Thomas
Principles of Canine and Feline Blood Collection, Processing, and Storage / Anthony C G Abrams-Ogg, Shauna L Blois
Red Blood Cell Transfusion in the Dog and Cat / Mary Beth Callan
Transfusion of Plasma Products / Marjory B Brooks
Platelet and Granulocyte Transfusion / Anthony C G Abrams-Ogg, Shauna L Blois
Blood Transfusion in Large Animals / Margaret C Mudge
Blood Transfusion in Exotic Species / Anneliese Strunk, Anke C Stöhr
Transfusion Reactions / Nicole M Weinstein
Cellular Therapy / Steven E Suter, Steven Dow
Clinical Use of Hematopoietic Growth Factors / Steven E Suter
Clinical Blood Typing and Crossmatching / K Jane Wardrop
Species-Specific Hematology. Hematology of Dogs / Maggie R McCourt, Theresa E Rizzi
Hematology of Cats / Deanna M W Schaefer
Hematology of Equids / Kathleen P Freeman, Alison J Farr, Annalisa Barrelet
Hematology of Bovids / R Darren Wood
Hematology of Sheep and Goats / Jason Stayt
Hematology of Pigs / Catherine E Thorn, Andrew S Bowman, David Eckersall
Hematology of Rodentia / Amy L MacNeill
Hematology of Mustelids / Stacy Clothier, Cathy Johnson-Delaney
Hematology of Cavies / Samantha J M Evans, Kurt L Zimmerman
Hematology of Lagomorphs / Francisco O Conrado
Hematology of Laboratory Animals / Karyn E Enos, David M Moore
Hematology of Camelids / Susan J Tornquist
Hematology of Cervids / Bridget C Garner
Hematology of Paenungulata / Emma H Hooijberg
Hematology of Marine Mammals / Nicole I Stacy, Hendrik H Nollens
Hematology of Galliformes / Julie Piccione, Jessica Hokamp
Hematology of Psittacines / Diana Schwartz, Hugues Beaufrère
Hematology of Anseriformes / Jessica Hokamp, Julie Piccione
Hematology of Raptors / Jennifer Johns
Hematology of Ratites / Phillip Clark
Hematology of Elasmobranchs / Jill E Arnold, Alexa Delaune
Hematology of Salmonids / Jere Stern
Hematology of Ictaluridae / Patricia Gaunt
Hematology of Cyprinidae / Ilze K Berzins, Alexander E Primus
Hematology of Lizards, Crocodilians, and Tuatara / Charlotte Hollinger, Jean A Paré
Hematology of Serpentes / Laura J Black, Marjorie Bercier
Hematology of Testudines / Jennifer D Steinberg, Stephen J Divers
Hematology of Amphibians / Perry Bain, Kendal E Harr
Hematology of Invertebrates / Jill E Arnold
Quality Management and Laboratory Techniques. Quality Management of Hematology Techniques / Martina Stirn, Kathleen P Freeman
Total Error and Proficiency Testing / Sten Westgard, Kathleen P Freeman
Quantitative Diagnostic Test Validation / Bente Flatland
Reference Intervals and Decision Limits / Kristen R Friedrichs, Asger Lundorff Jensen, Mads Kjelgaard-Hansen
Bone Marrow Evaluation / Natali B Bauer, Kendal E Harr
Flow Cytometry / Unity Jeffery
Testing for Immune-Mediated Hematologic Disease / K Jane Wardrop, Melinda J Wilkerson, Cinzia Mastroril Electrophoresis and Acute-Phase Proteins / Alessia Giordano
Molecular Diagnostic Techniques / Robert J Ossiboff
Genetic Evaluation of Inherited Hematologic Diseases / Noa Safra, Danika Bannasch
SECTION 10 GLOSSARY
INDEX

Contents:
General principles of psychopharmacological treatment
Diagnosis and classification
Antidepressants
Antipsychotic drugs
Mood stabilizers
Antianxiety agents
Hypnotics
Stimulants and other fast-acting drugs
Augmentation strategies for treatment-resistant disorders
Emergency department treatment
Pharmacotherapy for substance use disorders
Pharmacotherapy in special situations
Laboratory-guided pharmacotherapy.

Summary: This thoroughly updated 4th Edition of this highly regarded text continues to provide the latest therapeutic and surgical information on nail disease and disorders. It expands and updates all areas of onychology, including the newest in diagnostic techniques for nail diseases, a segment of dermatology that not only proves more difficult than cutaneous disorders but also is an exciting and innovative area on the frontier of skin research. Scher and Daniel's Nails: Diagnosis, Surgery, Therapy provides an update of therapeutic advances to help the resident, practitioner, and related healthcare provider (podiatrist, nurse, primary care physician, and all involved in nail care). A major section is devoted to nail surgery and nail pathology, both of which have been behind compared to other aspects of dermatology. There is also extensive information on the billion dollar nail cosmetics industry, which will bring this text to the attention of all nail technicians (several hundred thousand in the US alone) as well as to cosmeticians and manufacturers.

Contents:
SECTION ONE
SIGNS AND SYMPTOMS- Nail Signs and Symptoms
SECTION TWO
THE NORMAL NAIL- Historic Aspects of Nail Disease
Structure and Function of the Nail Unit
SECTION THREE
DIAGNOSTIC TECHNIQUES
An Approach to Initial Examination of the Nail
Subungual Exostosis, Nail Disease and Radiologic Considerations
Histopathology
SECTION FOUR
THE ABNORMAL NAIL- Pigmentation Abnormalities
Brittle Nails
Simple Onycholysis
Simple Chronic Paronychia
Dermatological Diseases
Onychomycosis
Podiatric Approach to Onychomycosis
Nonfungal Infections and Acute Paronychia
Nails in Systemic Disease
Systemic Drugs
Tumors of the Nail Apparatus
Occupational Nail Disorders
Disorders of the Nail Unit due to Podiatric Biomechanical Considerations
Nail Cosmetics: The Benefits and Pitfalls
Pediatric Diseases
Nails In Older Individuals
SECTION FIVE
THERAPEUTIC TECHNIQUES
Basic and Advanced Nail Surgery (Part 1: Principles and Techniques)
Basic and Advanced Nail Surgery (Part 2: Indications and Complications)
Glossary.

Summary: "The 9th Edition brings you fully up to date in the field, with coverage of new diagnostic tools, new information on drug-induced liver injury and cytopathology, and many new high-quality illustrations. Throughout the text, you'll find technical tips, diagnostic clues, and pearls that reflect the extensive experience and insight of the late Dr. Peter Scheuer and internationally renowned author Dr. Jay Lefkowitch, making this new edition your standard bench-side guide to today's liver biopsy diagnosis"--Publisher's description.

Contents:
General principles of biopsy assessment
Laboratory techniques
The normal liver
Assessment and differential diagnosis of pathological features
Biliary disease
Acute viral hepatitis
Steatosis, steatohepatitis and related conditions
Drugs and toxins
Chronic hepatitis
Cirrhosis
Neoplasms and nodules
Vascular disorders
Childhood liver disease and metabolic disorders
Disturbances of copper and iron metabolism
The liver in systemic disease and pregnancy
The liver in organ transplantation
Electron microscopy and other techniques.

Contents:
Overview: Clinical Fundamentals of Hepatology. History Taking and Physical Examination for the Patient with Liver Disease / Esperance A Schaefer, Lawrence S Friedman
Laboratory Tests, Noninvasive Markers of Fibrosis, Liver Biopsy, and Laparoscopy / Michael P Curry, Lennox J Jeffers
Noninvasive and Invasive Imaging of the Liver and Biliary Tract / Koushik K Das, Matthew A Morgan, Gregory G Ginsberg
General Considerations. Physioanatomic Considerations / Ian R Wanless
Bilirubin Metabolism and Jaundice / Allan W Wolkoff, Paul D Berk
Hepatic Histopathology / Zachary D Goodman
Mechanisms of Liver Injury / Harmeet Malhi, Gregory J Gores
Hepatic Manifestations of Systemic Disorders / Stuart C Gordon, Humberto C Gonzalez
The Liver in Pregnancy / Nancy Reau, Yannick Bacq
Consequences of Liver Disease. Hepatic Fibrosis / Scott L Friedman
Preoperative Evaluation of the Patient with Liver Disease / Patrick S Kamath, Mark T Keegan
Management of Portal Hypertension / Guadalupe Garcia-Tsao, Juan G Abraldes
Renal Complications of Liver Disease and the Hepatorenal Syndrome / Xingxing S Cheng, W Ray Kim
Pulmonary Manifestations of Liver Disease / Michael B Fallon, Anil Seetharam
Ascites and Spontaneous Bacterial Peritonitis / Vicente Arroyo, Javier Fernández
Hepatic Encephalopathy / Chathur Acharya, Jasmohan S Bajaj
Acute Liver Failure / Robert J Fontana, Khurram Bari
Acute-on-Chronic Liver Failure / Florence Wong
Malnutrition and Liver Disease / Craig McClain, Irina Kirpich, Laura Smart
Cholestatic Disorders. Primary Sclerosing Cholangitis / John M Vierling
Primary Biliary Cholangitis / Cynthia Levy, Andres F Carrion, Marlyn J Mayo
Autoimmune Hepatitis / Gideon M Hirschfield, Gwilym J Webb
Viral Hepatitis. Hepatitis A and E / Kenneth E Sherman, Shyam Kottilil
Hepatitis B and D / Marc G Ghany, Naveen Gara
Hepatitis C / Michael W Fried, Jama M Darling, Stanley M Lemon
Alcohol- and Drug-induced Liver Disease. Alcoholic Liver Disease / Mack C Mitchell, Gyongyi Szabo
Drug-induced Hepatotoxicity / Dominique Larrey, Jose Ursic-Bedoya, Lucy Meunier
Mechanisms of Drug-induced Liver Injury / Paul B Watkins, Merrie Mosedale
Genetic and Metabolic Disease. Wilson Disease / Michael L Schilsky, Aftab Ala
Hemochromatosis and Iron Storage Disorders / Kris V Kowdley, Priya Handa
Alpha-1 Antitrypsin Deficiency / David H Perlmutter
Nonalcoholic Fatty Liver Disease / Curtis K Argo, Zachary H Henry, Stephen H Caldwell
Vascular Diseases of the Liver. Vascular Liver Disease / Dominique-Charles Valla
The Liver in Circulatory Failure / Santiago J Munoz, Hanisha R Manickavasagan, Idean Amirjazil
Benign and Malignant Tumors; Cystic Disorders. Benign Tumors, Nodules, and Cystic Diseases of the Liver / Julien Calderaro, Jessica Zucman-Rossi
Hepatocellular Carcinoma / Maddie Kubiliun, Jorge A Marrero
Surgical Options in Liver Cancers / Garrett R Roll, John Paul Roberts
Infectious and Granulomatous Disease. Amoebic and Pyogenic Liver Abscesses / Marco A Olivera-Martínez, David Kershenobich
Parasitic Diseases / Michael A Dunn
Granulomas of the Liver / James H Lewis
Elements of Liver Transplantation. Selection of Candidates and Timing of Liver Transplantation / Meaghan Phipps, Alyson N Fox, Robert S Brown
Immunosuppression: The Global Picture / Caroline C Jadlowiec, Timucin Taner, Russell H Wiesner
The First Six Months Following Liver Transplantation / K Rajender Reddy, Manuel Mendizabal
Long-term Management of the Liver Transplant Patient / Timothy M McCashland
The Liver Transplant Procedure / Bijan Eghtesad, Koji Hashimoto, John Fung
Recurrent Disease Following Liver Transplantation / Haripriya Maddur, Josh Levitsky
The Role of Retransplantation / Peter L Abt, Kim M Olthoff
Controversies in Liver Transplantation / James F Trotter.

Summary: This book covers all details for a successful control and elimination strategy against propagation of deadly liver and intestinal flukes of the genus Schistosoma in China. Cancer due to schistosomiasis is still common in subtropical countries and affords hundred thousands of human and animal deaths per year. Expert authors play close attention to the biology and morphologic aspects of Schistosoma species as well as the history and status quo of schistosomiasis epidemiology. In a unique way, the present work illustrates the need to involve strategic measurements, and to control both adult worms and larval parasite stages. With a special focus on Jiangxi Province, the authors present an effective management plan, ranging from intermediate host snail control to diagnostic tools, medical aid, as well as public health education. This approach from China can be used as blueprint in other countries hit by the same worm infections. The contents of this book will thus be meaningful for academics and practitioners in the fields of parasitology, public health, as well as human and veterinary medicine.

Contents:
Schistosomes: Trematode Worms That Endanger Still Today Millions of Humans and Animals
The History and Experiences of Schistosomiasis Control in China
Epidemic Characteristics of Schistosomiasis in Jiangxi Province
The Course of Schistosomiasis Control in Jiangxi
Experiences and Cases on Schistosomiasis Control Research
Eliminating Plan and Challenges
Epilogue.

Summary: "Schizophrenia: Recent Advances in Diagnosis and Treatment is a major addition to the literature, offering practical, comprehensive coverage of diagnosis and treatment options, genetic issues, neuroimaging, long-term management of schizophrenia, and future directions and predictions of how clinical care of schizophrenia will change. The book is divided into five sections. Section 1 summarizes the present state of knowledge about the diagnosis and treatment of schizophrenia. This includes recent changes in the DSM 5 categorization of schizophrenia and its implications for treatment. Section 2 considers recent discoveries into its pathoetiology, including the status of biological markers, genetics and neuroimaging as they relate to diagnosis and potential novel therapeutic approaches. Section 3 explores the optimization of present therapeutic approaches; novel treatments; and management of the substantial risks associated with both the illness and its present therapies. Section 4 discusses progress in the long-term management of schizophrenia, focusing on biological and psychotherapeutic strategies to improve functioning and facilitate recovery. Section 5 considers future directions and predictions of how diagnosis and treatment of schizophrenia will change. An invaluable addition to the field, Schizophrenia: Recent Advances in Diagnosis and Treatment is a definitive resource that will be of great interest to all clinicians caring for patients with schizophrenia."--Publisher's website.

Summary: By 2050, the number of people aged sixty years and older with schizophrenia is expected to double and affect about 10 million people worldwide. Psychoses are among the most common experiences in later life, with a lifetime risk of 23 percent. As a result, there is a looming crisis in mental health care. Schizophrenia and Psychoses in Later Life is the first major multidisciplinary reference on these important disorders. The book provides guidelines for clinical care, research and policy that are consistent with the emerging paradigmatic changes occurring with respect to schizophrenia in later life. This book features multidisciplinary contributions from experts in the fields of biological psychiatry, social psychiatry, sociology, anthropology, social work, psychology, and neuropsychology that will help professionals to integrate services and attain the best outcomes. The text will guide psychiatrists, psychologists, gerontologists, policymakers, and social scientists in creating innovative new programs to help this underserved and growing population.

Summary: The Scholarly Communications Cookbook features 84 recipes that can help you establish programs, teach concepts, conduct outreach, and use scholarly communications technologies in your library. The book is divided into 4 thorough sections. Recipes can be used by those new to scholarly communications, early-career librarians, and more experienced professionals looking for fresh ideas for their institution.

Contents:
Part 1: Foundations
1. The history and future of school mental health
2. Who are the school mental health professionals?
Part II. School mental health interventions
3. Engaging adolescents in secondary schools
4. Supporting students following school crises: From the acute aftermath through recovery
5. Enhancing attention and organization in adolescents
6. Managing disruptive behavior
7. Regulating emotions
8. Emotion regulation and social functioning in adolescence: Conceptualization and treatment
9. Working with adolescents with autism spectrum disorder
10. Addressing adolescent drug abuse
11. Managing chronic health concerns
Part III. Special topics
12. Screening and progress monitoring in secondadry schools
13. Classroom-based services for adolescents with mental health needs
14. Consultation and collaboration to increase integrity in school mental health
15. Mental health promotion with aboriginal youth: Lessons learned from the uniting our nations program.

Summary: Significant shifts in community violence have created a need for greater awareness of character development and violence prevention in schools. Since the first edition (2008), public concern generated by high-profile shootings and other violence in schools has only increased. Now more than ever, effective strategies for preventing violence, treating victims, and assessing at-risk children are needed. This new edition, an update of contemporary issues of school violence, is a compendium of theory, research, and applied models that addresses violence and critical ingredients in prevention interventions in schools. The book uniquely addresses psychiatric input on neurobiology of trauma and victimization of children who experience school violence. Authored by clinicians, counselors, educators, researchers, and other professionals, the volume covers new approaches to primary prevention in schools and new contributors including a school superintendent, school safety officer, and specialists who treat relationship and dating violence. New topics include guidelines for school personnel that address exploitation of teenagers due to sex trafficking, and perspectives of parents whose children were victims of abuse and violence in schools. Among the topics explored: Developmental Issues in the Prevention of Aggression and Violence in School Updated Perspectives on Linking School Bullying and Related Youth Violence Research to Effective Prevention Strategies The Role of School District Superintendent in School Violence and Prevention: Softening Schools While Hardening Buildings Role of Law Enforcement in School Violence Prevention Through Positive Intervention and Relationship-Building Empowering Children to Prevent Violence School Violence and Primary Prevention is a critical and timely resource for school, medical, and mental health professionals working with children. It is also useful for students in public health, education, social work, psychology, and counseling-focused education. Dr. Miller has again made a major contribution on a most pressing issue of our time: school violence. The book covers the landscape of this psychosocial problem including cultural, developmental, intergenerational, racial, and gender aspects as well as approaches and solutions." -James J. Clark, Provost & EVP, Florida State University.

Contents:
Part I: Conceptualizing School Violence
1. School-Related Violence: Definition, Scope, and Prevention Goals
2. The Neurobiology of Violence and Victimization: Etiology, Biological Substrates, Clinical Implications, and Preventive Strategies
3. Developmental Issues in the Prevention of Aggression and Violence in School
4. Urban School Violence: Responding with Culture and Protective Factors Among Youth of Color
5. Gendered Harassment in Adolescence
6. Intergenerational Experiences of Bullying, Violence, Support and Survival Skills in Schools
Part II: Factors and Forms of School Violence
7. Updated Perspectives on Linking School Bullying and Related Youth Violence Research to Effective Prevention Strategies
8. School-related Violence During the COVID-19 Pandemic
9. Sexual Exploitation, Abuse and Trafficking of School-Aged Children
10. Relationship and Dating Violence in School-aged Adolescents
11. School Shootings and Clinical Management: Directions Toward Prevention
12. Boundary Violations, Harassment, Abuse, and Exploitation in the School Setting
13. Harassment, Abuse and Violence on the College Campus
Part III: Key Personnel in Addressing Violence in Schools
14. The Role of School District Superintendent in School Violence and Prevention: Softening Schools While Hardening Buildings
15. Role of Law Enforcement in School Violence Prevention Through Positive Intervention and Relationship-Building
16. Toward Understanding Classroom Socialization: Teacher Roles in Peer Victimization
17. The Psychiatrists Role After a School Shooting: The Emergency Room and Beyond
18. Preventing Violence Through Coordinated Responses to Classroom Disruption
Part IV: Prevention Interventions for School-Related Violence
19. Public Health Approach to Gun Violence Prevention in Connecticuts Youth
20. Trauma-Informed Care as a Framework to Reduce Trauma and Violence in Schools
21. Bullying as a Form of Abuse: Conceptualization and Prevention
22. Mindfulness Strategies for Primary Prevention
23. Equipping Students Minds with a Cognitive Training Program for Preventing School Violence
24. Character Education Update: Building a Buffer Against School Violence
25. Building Empathy, Step-by-Step: Prevention Intervention to Promote School Health
26. Preventing Compassion Fatigue Among Educators: An Educator Resiliency Study During the COVID-19 Pandemic
27. Utilizing Effective Bullying Prevention Programs
28. Empowering Children to Prevent Violence
29. School Violence: Lessons Learned and New Directions.

Summary: "Pharmacotherapy Casebook: A Patient-Focused Approach uses 150+ cases to help you build the clinical decision-making skills required to identify and resolve commonly encountered medication therapy problems encountered in daily practice. Providing a consistent, practical approach, this authoritative guide delivers everything you need to master patient communication, care plan development, and documenting interventions. Case chapters are organized into system sections that correspond to those of the companion textbook. The case-based approach makes this an ideal resource for PharmD, Nurse Practitioner, and other allied health courses" --Publisher's site.

Contents:
Principles of Patient-Focused Therapy
Cardiovascular Disorders
Respiratory Disorders
Gastrointestinal Disorders
Renal Disorders
Neurologic Disorders
Psychiatric Disorders
Endocrinologic Disorders
Gynecologic and Obstetric Disorders
Urologic Disorders
Immunologic Disorders
Bone and Joint Disorders
Eyes, Ears, Nose, and Throat Disorders
Dermatologic Disorders
Hematologic Disorders
Infectious Diseases
Oncologic Disorders
Nutrition and Nutritional Disorders
Complementary and Alternative Therapies (Level III).

Summary: This book is a fresh and readable account of the Covid-19 pandemic and how scientists and medical doctors are helping governments to manage the crisis. The book contains interviews and exchanges with dozens of scientists, doctors, experts, government representatives, and journalists. Why do some of the most scientifically advanced countries have the highest Covid-19 mortality? During the pandemic, the research community has been at the heart of and actor in global scandal. Why has science failed? With the help of numerous testimonies from China, France, the UK and the USA in particular, the book provides an insider view on this major crisis. Although the governments of these countries based their Covid-19 strategy on science, scientists failed to have a decisive influence on decision-makers except in China which created genuine time bombs. The accelerated development of vaccines does not erase past months' errors. The crisis led to the development of science politics at an unprecedented rate. More worryingly, experts themselves acknowledge that they did not rise to the challenge. Covid-19 also highlighted the weakness of democratic regimes and the power of technocapitalism. Countries pulled down their blinds, locked their doors, and promoted national approaches rather than international cooperation. The author proposes to set up an international framework on health risk to co-construct decision-making. He advocates political distancing in order to put the basics first: develop science, fight ignorance.

Contents:
A Microscopic Killer
COVID-19 Diary
Geopolitics of the Coronavirus
Political Distancing.

Summary: The main focus of this book is providing evidence on and interpreting the risks associated with heated tobacco products (HTPs) in terms of their health effects and social effects; in addition, the author introduces a harm reduction theory related to HTPs and electronic cigarettes. The book also addresses the history of these products, their marketing strategies, and policy implications. These products are new and the accompanying health risks have yet to be determined. However, since Japan accounts for more than 80% of the world's market for IQOS, the most popular heated tobacco product, researchers around the globe will be very interested in the outcomes. Written by a leading researcher in the field of tobacco control, Science and Practice for Heated Tobacco Products offers a valuable, unique resource for researchers in the fields of epidemiology, public health, social sciences, addiction, and tobacco research. Since tobacco is associated with a host of diseases including cancers, cardiovascular diseases, diabetes mellitus, and respiratory illnesses, researchers and healthcare workers whose work involves these diseases will find this book both thought provoking and insightful.

Contents:
1 Introduction
2 Tobacco Products in Japan including a History of Heated Tobacco Products
3 The JASTIS project: product use status in Japan
4 Marketing Strategy for Tobacco Products in Japan
5 Substances in Novel Tobacco Products
6 Health effect
7 Social Effect
8 Interpretation of Risks of Novel Tobacco Products, including Harm Reduction Theory
9 Suggestions for Practice regarding Novel Tobacco Product Use Patterns
10 Policy implication including interference in tobacco control measures with new tobacco products
11 Conclusions.

Summary: This book provides a clear and comprehensive guide to the clinical prescription of lithium that draws upon evidence-based knowledge of its mechanisms of action. The book is divided into two parts, on the science of lithium and the practice of lithium therapy. The former covers aspects such as the properties of the lithium ion, pharmacokinetics and pharmacodynamics, impact on neurotransmission, and gene expression modulation. The section on practice includes discussion of variability in response to lithium, use of lithium in the treatment of bipolar disorders, its value in suicide prevention, administration during pregnancy and in the pediatric age group, and side effects. Lithium is arguably the only true mood stabilizer, and its multifaceted effects across many clinical domains have given rise to a resurgence of interest in recent years, fuelled by both researchers and clinicians. Nevertheless, its use remains constrained by exaggerated concerns about potential side-effects. In reality, lithium is a simple molecule that is relatively straightforward to administer and monitor and has potentially profound benefits at a fraction of the cost of contemporary agents. This book dispels the many myths and concerns that surround its use and will be of interest for clinicians and researchers worldwide.

Contents:
Section I: Science of Lithium: The Ion : Lithium
Pharmacokinetics and pharmacodynamics of lithium
Lithium : neurotransmission and cellular mechanisms pathways underlying neuroprogression in bipolar disorder
Lithium on gene expression modulation
Neuroimaging and lithium
Conclusion: overview of potential mechanisms of action of lithium in bipolar disorder
Section II: Practice of Lithium Therapy
Introduction of lithium in Medicine and Psychiatry
Lithium Response variability
Lithium Response variability: Pharmacogenomics studies
Lithium Response variability: Biomarkers
Lithium in acute and maintenance treatment of bipolar disorders
Lithium and suicide prevention
Lithium in Bipolar disorders international guidelines
Lithium and pregnancy
Lithium in children and adolescents
Short and mid-term side effects of lithium
Lithium, kidneys, renal failure
Lithium intoxication
Discontinuation and re-use of lithium
Conclusion : overview of indications and monitoring of lithium in bipolar disorders.

Summary: This updated volume provides the current knowledge on the diagnosis, treatment, management, and prevention of pressure ulcers. Chapters on the early detection of pressure ulcers, negative pressure therapy, pressure ulcers in pediatric patients, adjunctive therapies, surgical management of pressure ulcers, and innovation in pressure ulcer research and practice are included. This second edition aims to be the primary reference for pressure ulcers from diagnosis and prevention to management and treatment options. The book is relevant to dermatology clinicians, vascular surgeons, and dermatology nurses.

Contents:
The potential of biomarkers in the early detection of pressure ulcers
The critical characteristics of a good wheelchair cushion
Epidemiology of pressure ulcers
Nutrition and pressure ulcers
Health related quality of life (HRQOL) implications for people with pressure ulcers
Incontinence-associated dermatitis (IAD) and pressure ulcers : an overview
Microclimate ; rediscovering an old concept in the aetiology of pressure ulcers
Skin care
Pressure ulcers in pediatric patients
Pressure ulcers after epidural anaesthesia
Advanced dressings in pressure ulcers
Adjunctive therpaies in pressure ulcers
Negitive pressure would therapy in the management of pressure ulcers
Surgical management of pressure ulcers
The Stop Pressure Ulcer Day and other initiatives by EPUAP
Innovation in pressure ulcers prevention and treatment.

Summary: This volume in the AAPS Advances series covers various quality, safety and clinical aspects of drug development that are relevant to new and/or generic drugs containing a complex mixture of molecules. Specific topics discussed include: raw materials sourcing; manufacturing controls; characterization; identification of critical product quality components and attributes; identification of impurities, particularly as they bear on toxicity and immunogenicity; clinical trial study design considerations, and the regulatory science applications to development of such complex mixtures. Complex mixtures are challenging to characterize and analyze using standard methods. Further challenges extend throughout the product development cycle from raw material control to clinical study design. The regulatory landscape is rapidly changing as new types of complex mixtures are introduced into clinical trials and to the market (e.g., traditional Chinese medicines and medical marijuana products), while older products are facing generic competition for the first time (e.g., enoxaparin). The future outlook for complex generic drug products, as opposed to the more commonly developed targeted single agent drug products is not clear. The risks pertaining to lack of a full understanding of raw material control, process and controls in manufacture, as well as characterization of a complex mixture were seen vividly during the heparin crisis of 2008. As such powerful lessons have been learned about the regulatory science specific to complex products. The Science and Regulations of Naturally Derived Complex Drugs addresses the interests among industry, academics, and government on the issues surrounding the future development of mixtures for medicinal use.

Contents:
Evolving Challenges in Developing Naturally-Derived Complex Mixtures into Drugs: U.S. Experience and Perspective
Regulatory Landscapes for Approval of Naturally-derived Complex Mixture Drugs
Complex Natural Product Heparin: Biosynthesis, Biology and Application via Synthetic Heparins
Traditional Chinese Medicine Herbal Drugs: From Heritage to Future Developments
Analytics on Farm-Dust Extract for Development of Novel Strategies to Prevent Asthma and Allergic Disease
Analytical Tools for Physicochemical Characterization and Fingerprinting
NMR in the Characterization of Complex Mixture Drugs
Mass Spectrometry in the Characterization of Complex Drugs
Scientific Considerations in the Approval of Complex Generi
Raw Materials Production and Manufacturing Process Control Strategies
Heparin Contamination and Issues Related to Raw Materials and Controls
Pharmacology and Toxicology Concerns of Impurities
Immunogenicity risks for Naturally Derived Complex Drugs
Development of Plant-Derived Mixtures as Botanical Drugs: Clinical Considerations
A Totality-of-Evidence Approach to Ensuring Therapeutic Consistency of Naturally Derived Complex Mixtures
Economic Considerations for Complex Mixture Drugs
Drug Discovery from Complex Mixtures: Serendipity, Screening and Characterization
Integrated Approach for Characterization of Highly Heterogeneous Drugs.

Summary: This book offers a timely review of modern technologies for health, with a special emphasis on wireless and wearable technologies, GIS tools and machine learning methods for managing the impacts of pandemics. It describes new strategies for forecasting evolution of pandemics, optimizing contract tracing, and for detection and diagnosis of diseases, among others. Written by researchers and professionals with different backgrounds, this book offers a extensive information and a source of inspiration for physiologists, engineers, IT scientists and policy makers in the health and technology sector.

Contents:
Introduction
Pandemics Behavior of One Year in Six Most Affected Countries using Polynomial Generated SIR Model
Digital contact tracing for COVID 19: a missed opportunity or an expensive mess
A Re-configurable Software-Hardware CNN Framework for Automatic Detection of Respiratory Symptoms
A Comprehensive Telemedicine Service in Hong Kong Provided Through a Mobile Application
Adapting to live in the global pandemic era: Case studies
Towards QR code health systems amid COVID-19 - Lessons learnt from other QR code digital technologies
Optimal testing strategies for infectious diseases.

Contents:
The generic model of cognitive behavioral therapy / Scott H. Waltman and Leslie Sokol
Treatment-relevant assessment in cognitive-behavioral therapy / Katerina Rnic and David J.A. Dozois
Learning principles in CBT / Michelle L. Davis, Sara M. Witcraft, Scarlett O. Baird and Jasper A.J. Smits
Cognitive processes in CBT / Eni S. Becker and Janna N. Vrijsen
Emotion regulation in cognitive-behavioral therapy / Andre J. Plate and Amelia Aldao
Combined treatment with CBT and psychopharmacology / Josie Lee, Bridget A. Hearon and Michael W. Otto
Acceptance and commitment therapy and the cognitive behavioral tradition / Frederick Chin and Steven C. Hayes
Mindfulness-based cognitive behavioral treatments / Lizabeth Roemer, Natalie Arbid, Jennifer H. Martinez and Susan M. Orsillo
Global to local / Anushka Patel and Devon Hinton
Cognitive-behavioral therapy in older adults / Elizabeth C. Conti, Cynthia Kraus-Schulman and Melinda A. Stanley
Cognitive-behavioral therapy for children and adolescents / Danielle Cornacchio, Amanda L. Sanchez, Tommy Chou and Jonathan S. Comer
Behavioral activation treatments for depression / Leanne Quigley and Keith S. Dobson
Posttraumatic stress disorder / Richard A. Bryant
Eating disorders / Zafra Cooper and Riccardo D. Grave
Transdiagnostic treatment for anxiety disorders / Laren R. Conklin and Hannah Boettcher
Cognitive behavioral therapy for sleep disorders / Caitlin E. Gasperetti, Michael R. Dolsen and Allison G. Harvey
Cognitive behavioral therapy for somafom disorders and / Maria Kleinstäuber and Winfried Rief
Dialectical behavior therapy / Anita Lungu and Marsha M. Linehan
Cognitive bias modification / Jennie M. Kuckertz and Nader Amir
Cognitive training in schizophrenia / Kristen M. Haut, Vijay A. Mittal, Stewart A. Shankman and Christine I. Hooker
Internet-based cognitive behavior therapy / Gerhard Andersson, Per Carlbring and Heather D. Hadjustavropoulos
Virtual reality and other realities / Cristina Botella, Rosa M. Baños, Azucena García-Palacios and Soledad Quero.

Summary: "Consciousness concerns awareness and how we experience the world. How does awareness, a feature of the mental world, arise from the physical brain? Is a dog conscious, or a jellyfish, and what explains the difference? How is consciousness related to psychological processes such as perception and cognition? The Science of Consciousness covers the psychology, philosophy, and neuroscience of consciousness. Written for introductory courses in psychology and philosophy, this text examines consciousness with a special emphasis on current neuroscience research as well as comparisons of normal and damaged brains. The full range of normal and altered states of consciousness, including sleep and dreams, hypnotic and meditative states, anesthesia, and drug-induced states, as well as parapsychological phenomena and their importance for the science of consciousness is covered, as well as the 'higher' states and how we can attain them. Throughout the text attempts to relate consciousness to the brain."-- Provided by publisher.

Summary: "The Science of Paediatrics, MRCPCH Mastercourse, provides essential background preparation for the MRCPCH Theory and Science examination. It contains an up-to-date review of the application of science to everyday paediatric clinical practice, whether it is interpreting clinical signs or investigations, prescribing drugs or identifying best management. Although this understanding is essential in order to make informed clinical decisions, it is difficult to obtain as it is not usually covered in clinical textbooks"-- publisher's description.

Contents:
Front Matter. Copyright. Foreword. Preface. List of Contributors. 1. The role of science and research in paediatrics
2. Epidemiology and public health
3. History and examination
4. Normal child development
5. Developmental problems and the child with special needs
6.Paediatric emergencies and critical care
7. Accidents and poisoning
8. Child protection
9. Genetics
10. Perinatal medicine
11. Neonatal medicine
12. Growth and puberty
13. Nutrition
14. Gastroenterology
15. Infection and immunity
16. Allergy
17. Respiratory medicine
18. Cardiology
19. Nephrology
20. Genital disorders
21. Hepatology
22. Oncology
23. Haematology
24. Child and adolescent mental health
25. Dermatology
26. Diabetes and endocrinology
27. Musculoskeletal disorders
28. Neurology
29. Metabolic medicine
30. Ophthalmology
31. Hearing and balance
32. Adolescent medicine
33. Global child health
34. Palliative medicine
35. Ethics
36. Pharmacology and therapeutics
37. Clinical research
38. Statistics
39. Evidence-based paediatrics
40. Quality improvement and the clinician.

Summary: "Introduces all of the essential cell biology and developmental biology background for the study of stem cells. This book gives you all the important information you need to become a stem cell scientist. It covers the characterization of cells, genetic techniques for modifying cells and organisms, tissue culture technology, transplantation immunology, properties of pluripotent and tissue specific stem cells and, in particular, the relevant aspects of mammalian developmental biology. It dispels many misconceptions about stem cells, especially that they can be miracle cells that can cure all ills. The book puts emphasis on stem cell behavior in its biological context and on how to study it. Throughout, the approach is simple, direct, and logical, and evidence is given to support conclusions. Stem cell biology has huge potential for advancing therapies for many distressing and recalcitrant diseases, and its potential will be realized most quickly when as many people as possible have a good grounding in the science of stem cells. Content focused on the basic science underpinning stem cell biology Covers techniques of studying cell properties and cell lineage in vivo and in vitro Explains the basics of embryonic development and cell differentiation, as well as the essential cell biology processes of signaling, gene expression, and cell division Includes instructor resources such as further reading and figures for downloading Offers an online supplement summarizing current clinical applications of stem cells Written by a prominent leader in the field, The Science of Stem Cells is an ideal course book for advanced undergraduates or graduate students studying stem cell biology, regenerative medicine, tissue engineering, and other topics of science and biology."-- Provided by publisher.

Contents:
Chapter 1. Uncertainty in clinical medicine
Chapter 2. The logic of medicine
Chapter 3. Probability: uncertainty quantified
Chapter 4. Decision making: making choices
Chapter 5. Solving unstructured problems
Chapter 6. Therapeutic decision making
Chapter 7. Evidence-based medicine
Chapter 8. Improving the quality of care
Chapter 9. Common fallacies
Chapter 10. Putting this book into practice
Appendix 1. More on probability curves
Appendix 2. More on likelihood ratios
Appendix 3. The minimum Bayes factor and likelihood ratios.

Summary: This book outlines, from a surgeon's standpoint, how physicians and mid-level providers working at wound care centres can expeditiously and effectively manage wounds. It comprehensively addresses the concept of wound healing, from the healing process to debridement concepts, and various antiseptics and local antibiotics used in dressing materials to facilitate healing. The book also discusses the latest inventions and treatment options that have revolutionized wound healing, such as: oxygen therapy, ozone therapy, hyperbaric oxygen therapy, electric therapy and ultrasonic wound therapy. In closing, it examines the latest regenerative therapies based on stem cell therapy, cellular therapy and gene therapy. Given its scope, the book offers a valuable resource for medical students and physicians dealing with wound management, as well as a reference guide for nurses in primary and tertiary wound care settings.

Contents:
Chapter 1. Introduction
Chapter 2. Pathophysiology of wound healing
Chapter 3. Debridement
Chapter 4. Antiseptics and local antibiotics. Chapter 5. Absorbent dressings (simple gauze and others). Chapter 6. Moisturizing dressings
Chapter 7. Other types of dressings
Chapter 8. Other modalities of treatment
Chapter 9. Growth factors and hormones
Chapter 10. Regenerative therapy
Chapter 11. Offloading, footwear and immobilization
Chapter 12. Management of hypertrophic scar
Chapter 13. Different types of wounds.

Contents:
A review of classic physiological systems
Systems integration : psychoneuroimmunology
The stress system
The relaxation system : theoretical construct
The relaxation system : therapeutic modalities
Energy medicine : cutting-edge modalities
Energy medicine : focus on non-thermal electromagnetic therapies
Energy medicine : focus on lasers
The four pillars and two guideposts for the healing professions
The pineal gland : energy transducer
Soul medicine : crossing the boundary
Human epigenetics in health and disease
History and philosophy of naturopathic medicine
Wellbeing
Assessing the toxic load and detoxification strategies
Precision nutrition
The landscape of integrative medicine in America with a shift to prevention and health promotion
Whole person caring
Energy medicine : focus on lasers.

Contents:
v. 1, Analytical aspects.

Contents:
v.1 - Renal disorders infections and calculi. v.2 - Urogenital tract, oncology and the urological armamentarium.

Summary: In the modern era, zoos and aquariums fight species extinction, educate communities, and advance learning of animal behaviour. This book features first person stories and scientific reviews to explore ground breaking projects run by these institutions. Large-scale conservation initiatives that benefit multiple species are detailed in the first section, including critical habitat protection, evidence-based techniques to grow animal populations and the design of community education projects. The second section documents how zoos use science to improve the health and welfare of animals in captivity and make difficult management decisions. The section on saving species includes personal tales of efforts to preserve wild populations through rehabilitation, captive breeding, reintroduction, and public outreach. The concluding section details scientific discoveries about animals that would have been impossible without the support of zoos and aquariums. The book is for animal scientists, zoo professionals, educators and researchers worldwide, as well as students of zookeeping and conservation.

Contents:
v. 1. Studies in cellular physiology
v. 2. Radical dietary treatment of vasular and metabolic disorders.

Summary: The ability to write clearly is critical to any scientific career. The Scientist's Guide to Writing provides practical advice to help scientists become more effective writers so that their ideas have the greatest possible impact. Drawing on his own experience as a scientist, graduate adviser, and editor, Stephen Heard emphasizes that the goal of all scientific writing should be absolute clarity; that good writing takes deliberate practice; and that what many scientists need are not long lists of prescriptive rules but rather direct engagement with their behaviors and attitudes when they write. He combines advice on such topics as how to generate and maintain writing momentum with practical tips on structuring a scientific paper, revising a first draft, handling citations, responding to peer reviews, managing coauthorships, and more. In an accessible, informal tone, The Scientist's Guide to Writing explains essential techniques that students, postdoctoral researchers, and early-career scientists need to write more clearly, efficiently, and easily. Emphasizes writing as a process, not just a productEncourages habits that improve motivation and productivityExplains the structure of the scientific paper and the function of each partProvides detailed guidance on submission, review, revision, and publicationAddresses issues related to coauthorship, English as a second language, and more.

Contents:
Frontmatter
Contents
Preface
Part I. What Writing Is
1. On Bacon, Hobbes, and Newton, and the Selfishness of Writing Well
2. Genius, Craft, and What This Book Is About
Part II. Behavior
3. Reading
4. Managing Your Writing Behavior
5. Getting Started
6. Momentum
Part III. Content and Structure
7. Finding and Telling Your Story
8. The Canonical Structure of the Scientific Paper
9. Front Matter and Abstract
10. The Introduction Section
11. The Methods Section
12. The Results Section
13. The Discussion Section
14. Back Matter
15. Citations
16. Deviations from the IMRaD Canon
Part IV. Style
17. Paragraphs
18. Sentences
19. Words
20. Brevity
Part V. Revision
21. Self- Revision
22. Friendly Review
23. Formal Review
24. Revision and the "Response to Reviews"
Part VI. Some Loose Threads
25. The Diversity of Writing Forms
26. Managing Coauthorships
27. Writing in English for Non- Native Speakers
Part VII. Final Thoughts
28. On Whimsy, Jokes, and Beauty: Can Scientific Writing Be Enjoyed?
Acknowledgements
References
Permanent URLs
Index.

Summary: This book offers a concise but comprehensive overview of scleritis, with up-to-date information on all aspects, including diagnosis and treatment. Fundamental features of the pathogenesis of scleral inflammation are first discussed as a basis for understanding the therapeutic strategies. Detailed descriptions are then provided of clinical manifestations, the complications that can arise during the course of the disease process, and the best way to manage them. An individual chapter is devoted to infectious scleritis and its management, this being an uncommon but serious condition that may result not only in loss of vision but also in loss of the globe itself. The diagnostic approach to and various management options for scleritis are then discussed extensively, with coverage of local and systemic therapy and new strategies, including biologics. Apart from the potential impact on vision, inflammation of the sclera carries a risk of association with systemic diseases, some of which can prove fatal if not promptly recognized and managed. This book is designed to allow ophthalmologists to easily identify the condition and the signs indicative of a more severe problem. It will thereby assist in safe and effective management, and help in preserving vision and life.

Contents:
General Considerations on Anatomy and Pathogenesis of Scleral Inflammation
Classification and Clinical Presentations
Associated Systemic Diseases
Infectious Scleritis
Diagnostic Approach to Scleritis
Complications and their Management
Management with Non-Steroidal Anti-Inflammatory Agents
Management with Steroids: Local and Systemic
Management with Immunosuppressive Therapy and Biologics.

Summary: Comprised of the authoritative work of international experts, this fully-updated second edition of Scleroderma builds upon the well-regarded approach in the first edition to provide integrated, concise, and up-to-date synthesis of current concepts of pathogenesis and modern approaches to management of systemic sclerosis (scleroderma). With a multidisciplinary approach to comprehensive care, this book is easily accessible for health care professionals in many fields. The new edition includes extensive updated material based on major developments in the field, with new chapters on personalized medicine, cancer complications, global perspectives on scleroderma, and more. It presents a succinct and thoughtful synthesis of current pathomechanistic concepts, providing a valuable reference tool for basic and translational investigators working in the field. Scleroderma: From Pathogenesis to Comprehensive Management serves as an essential, all-inclusive resource for rheumatologists, pulmonologists, cardiologists, gastroenterologists, nephrologists and all those involved in the care of scleroderma patients.

Contents:
Section I. Introduction
Historical Perspective of Scleroderma
Section II. Epidemiology, Genetics and Classification
Epidemiology, Environmental and Infectious Risk Factors
Genetic Factors
Disease Subsets in Clinical Practice
Evolving Concepts of Diagnosis and Classification
Overlap Syndromes
Juvenile Localized and Systemic Scleroderma
Morphea (Localized Scleroderma)
Scleroderma Mimics
Systems Biology Approaches to Understanding the Pathogenesis of Systemic Sclerosis
Section III: The Biological Basis of Systemic Sclerosis
Introduction: The Etiopathogenesis of Systemic Sclerosis: An Integrated Overview
Pathology of Systemic Sclerosis
Inflammation and Immunity
Autoantibodies as Markers and Possible Mediators of Scleroderma Pathogenesis
The Clinical Aspects of Autoantibodies
Mechanisms of Vascular Disease
Biomarkers in Systemic Sclerosis
Pathophysiology of Fibrosis in Systemic Sclerosis
Overview of Animal Models
Section IV. Cardiovascular Manifestations and Management
Raynaud's Phenomenon, Digital Ulcers, and Nailfold Capillaroscopy
Renal Crisis and Other Renal Manifestations of Scleroderma
Cardiac Involvement
Section V. Pulmonary Manifestations and Management
Overview of Lung Involvement: Diagnosis, Differential Diagnosis, and Monitoring
Clinical Assessment of Lung Disease
Treatment of Interstitial Lung Disease
Pathogenesis of Pulmonary Arterial Hypertension
Clinical Assessment of Pulmonary Hypertension
The Management of Pulmonary Arterial Hypertension in the Setting of Systemic Sclerosis
Section VI. Gastrointestinal Manifestations and Management
Overview of Gastrointestinal Tract Involvement
Upper Gastrointestinal Tract: Manifestations of Systemic Sclerosis
Small and Large Intestinal Involvement and Nutritional Issues
Section VII. Skin, Musculoskeletal and Other Complications
Calcinosis
Evaluation and Management of Skin Disease
Assessment and Management of Progressive Skin Involvement in Diffuse Scleroderma
Skeletal Muscle Involvement
Tendons, Joints, and Bone
Cancer in Systemic Sclerosis
Overlooked Manifestations
Pregnancy
Section VIII: Management and Outcome Assessment
Introduction to Section VIII: Management and Outcome Assessment
Immunomodulatory, Immunoablative, and Biologic Therapies
Investigative Approaches to Drug Therapy
Drug Development and Regulatory Considerations for SSc Therapies
Physical and Occupational Therapy
Psychosocial Issues and Care for Patients with Systemic Sclerosis
Clinical Trial Design in Systemic Sclerosis
Measuring Disease Activity and Outcomes in Clinical Trials
Innovative Approaches to Clinical Trials in Systemic Sclerosis
Molecular Stratification by Gene Expression as a Paradigm for Precision Medicine in Systemic Sclerosis
Section IX. Case Studies: Approach to Complex Clinical Problems
Managing the Ischemic Finger in Scleroderma
Scleroderma Renal Crisis
Rapid Diffuse Skin Disease with Progressive Joint Contractures
Management of the Scleroderma Patient with Pulmonary Arterial Hypertension Failing Initial Therapy
Pseudo-obstruction with Malabsorption and Malnutrition
Progressive Interstitial Lung Disease Non-Response to Cyclophosphamide
Coping with the Disfigurement of Scleroderma: Facial, Skin, and Hand Changes
Managing Complicated Digital Ulcers .

Contents:
1. Anatomy
2. Adverse Sequelae and Complications of Venous Hypertension
3. Pathophysiology of Varicose Veins
4. Pathophysiology of Telangiectasias
5. Noninvasive Examination of the Patient Before Sclerotherapy
6. Use of Compression Therapy
7. Mechanism of Action of Sclerotherapy
8. Complications and Adverse Sequelae of Sclerotherapy
10. Role of Surgery in the Treatment of Varicose Veins
11. Intravascular Approaches to the Treatment of Varicose Veins : Radiofrequency, Lasers and More
12. Clinical Methods for Sclerotherapy of Telangiectasias
13. Treatment of Leg Telangiectasias with Laser and High-Intensity Pulsed Light
14. Venoactive Drugs.

Summary: This newly released publication is an updated scope of practice statement and 17 revised standards for the clinical and administrative professional practice of ambulatory care registered nurses (RNs). The standards promote effective clinical and administrative management of increasingly complex ambulatory care RN roles and responsibilities in a changing health care environment.The 10th edition of the Scope and Standards of Practice for Professional Ambulatory Care Nursing contains some significant revisions from previous versions. In addition to the revised scope of practice, this publication contains 17 standards. The first six standards address the phases of the nursing process; the last 11 standards address professional performance.These changes offer clarification and specificity for the distinct domains of clinical and administrative nursing practice in ambulatory care settings. -- Provided by Publisher.

Contents:
Scope and standards revision task force
Overview of the AAACN standards 10th edition
Scope of practice for professional ambulatory care nursing
Standards of Practice for Professional Ambulatory Care Nursing. Standards of professional clinical practice
Standards of nursing organizational and professional performance.

Summary: "The Scope and Standards of Practice for Professional Ambulatory Care Nursing promotes effective clinical and administrative management of increasingly complex ambulatory care RN roles and responsibilities in a changing health care environment. The 9th Edition contains significant revisions from previous versions, including an updated Scope of Practice statement, as well as updates for the 16 standards of professional ambulatory care nursing practice. The scope of practice statement addresses the definition and unique characteristics of ambulatory care nursing, the conceptual framework, its history over the past 30 years, the diverse types of ambulatory care settings, the roles of ambulatory care RNs, the trends and issues in ambulatory care and future directions. The standards specify the competencies needed for professional clinical and administrative practice. The first six standards address the six phases of the nursing process; the last ten standards address Professional Performance. Each standard contains three sections: 1. A statement of the standard addressed. 2. Measurement criteria that may be used for demonstrating competency for meeting the standard. 3. Additional standard statements and measurement criteria for nurseexecutives, administrators, and managers. These changes offer clarification and specificity for the distinct domains of clinical and administrative nursing practice in ambulatory care settings. Use this resource to guide ambulatory care nursing role descriptions and competencies; improve or create policies, procedures, and standards; train and orient staff; create clinical, telehealth, and administrative job descriptions; stimulate participation in research and evidence-based practice; guide ethical practice and patient advocacy; and guide performance improvement initiatives in clinical and organizational environments."--Publisher's description.

Summary: "To better reflect its new and expanded content, the name of the 4th edition of Operative Anatomy has been changed to Essential Operative Techniques and Anatomy. In this latest edition, the text's focus on clinically relevant surgical anatomy will still remain, but it is now organized by anatomical regions rather than by procedures. Then to further ensure its relevance as a valuable reference tool, the number of chapters has been expanded to 134 and the color art program has also been increased significantly. Written for surgical residents, this book provides an up-to-date, easy-to-use reference for nearly all procedures with which they will face in their residency. Providing a blend of both surgical anatomy and a surgical atlas, this edition covers all Essential Common procedures from the SCORE curriculum as well as many of the Essential Uncommon procedures such as urgent operations seen in general surgery practice. FEATURES: Covers all Essential Common procedures in SCORE curriculum, Significantly expanded chapter on thoracoscopic surgery of the esophagus, Significantly expanded chapter on laparoscopic colon resection, New chapters on cutaneous infections, I & D, excision, STSG, ligation, stripping, saphenous vein, loop ileostomy/closure, operations for small bowel obstruction (including laparoscopic), and pediatric umbilical hernia repair"--Provided by publisher.

Contents:
1.Introduction: Scottish medicine and literary culture, 1726-1832 / Megan J. Coyer and David E. Shuttleton
2. 'Nothing is so soon forgot as pain': reading agony in Adam Smith's The theory of moral sentiments / Craig Franson --3. The origins of a modern medical ethics in enlightenment Scotland: Cheyne, Gregory and Cullen as practitioners of sensibility / Wayne Wild
4. The demise of the preformed embryo: Edinburgh, Leiden, and the physician-poet Mark Akenside's contribution to re-establishing epigenetic embryology / Robin Dix
5. Benjamin Rush, Edinburgh medicine and the rise of physician autobiography / Catherine Jones
6. The construction of Robert Fergusson's illness and death / Rhona Brown
7. 'Groaning under the miseries of a diseased nervous system': Robert Burns and melancholy / Allan Beveridge
8. Phrenological controversy and the medical imagination: 'A modern pythagorean' in Blackwood's Edinburgh Magazine / Megan J. Coyer
9. Blood and the revenant in Walter Scott's The Fair Maid of Perth / Katherine Inglis
10. Magic, mind control, and the body electric: "Materia Medica" in Sir Walter Scott's library at Abbotsford / Lindsay Levy
11. An Account of ... William Cullen: John Thomson and the making of a medical biography / David E. Shuttleton
12. Transatlantic irritability: Brunonian sociology, America and mass culture in the nineteenth century / Gavin Budge
Index.

Contents:
The Development of PGD
Elements of Informed Consent for Preimplantation Genetic Diagnosis
Follicular Recruitment & Oocyte Recovery in Assisted Reproduction
Biomarker-based Flow-Cytometric Semen Analysis for Male Infertility Diagnostics and Clinical Decision Making in ART
Comparison of Methods for Assessment of Sperm DNA Damage (Fragmentation) and Implications for the Assisted Reproductive Technologies
Tweaking ICSI for a PGD program
Comprehensive Chromosomal Screening from Polar Body Biopsy to Blastocyst Trophectoderm Sampling: Evidence and Considerations
Polar Body Diagnosis
An Alternative and Addition to Preimplantation Diagnosis
Efficiency of Polar Body Biopsy for Aneuploidy Screening by DNA Microarray for Single Embryo Transfer
Prediction of Embryo Viability by Morphokinetic Evaluation to Facilitate Single Transfer
Comparison of PCR Techniques for Embryo Screening and Single Embryo Transfer
Array CGH and Partial Genome Sequencing for Rapidly Karyotyping IVF Blastocysts Before Transfer
Single Embryo Transfers Enabled by aCGH
Current and Future Methodologies
SNP array, qPCR, and next-generation sequencing based comprehensive chromosome screening
Expanding PGD Applications to Non-traditional Genetic and Non-Genetic Conditions
Should molecular cytogenetic techniques be applied to facilitate single embryo transfer in egg donation cases? Assessment of frequency and distribution of embryo aneuploidy after anonymous donor oocyte IVF
Selecting the Single Embryo for Transfer in Mitochondrial Disorders
Single Embryo Transfer: The Significance of the Embryo Transfer Technique
The Vitrification Component: An Integral Part of a Successful eSET Program
A Review of Luteal Support Protocols for Single Embryo Transfers
Fresh and Frozen
Cost effectiveness of single embryo transfers relative to higher embryo transfer policies in clinical practice: A population based analysis
The Quebec experience
One plus one equals two at once: Presenting cumulative pregnancy rates as the ideal outcome in elective SET programs
Single Embryo Transfer in a State-Sponsored IVF Context: Current Experience from Israel
Single Embryo Transfer: the Quebec Experience
Regulatory Aspects of Embryo Testing: An American View
Regulatory Challenges in Assisted Reproduction: A European Perspective
Preimplantation Genetic Screening: Ethics & Policy
Crossing Rubicons: Assisted Reproductive Therapies and Remaining Human.

Summary: The Scrub's Bible represents an entry level guide to understanding the human eye, its basic anatomy, and physiology. It includes details on the fundamentals of the two most common areas of ophthalmic surgery: cataract and corneal/refractive surgery.

Contents:
1. Introduction
2. The Evolution of Eye Surgery
3. The Advent of Ambulatory Eye Surgery
4. The Eye and its Anatomical Considerations
5. How We See
6. Contemplating Cataract Surgery
7. How the Patient Gets From the Front Door of the ASC to Your OR Suite
8. Decorum in the OR
9. Infection Control
10. Setting Up Your OR Suite
11. The Phaco Machine
12. Setting Up the Phaco Machine
13. Trouble-Shooting the Phaco Machine
14. Cataract Surgery: More Than One Way to Skin a Cat
15. Femto Laser Assisted Cataract Surgery (FLACS)
16. Performing Phaco
17. Determining Lens Power and Design: Lens Implants and Implantation
18. Glaucoma Treatment as an Adjunct to Cataract Surgery
19. Complications Encountered, Instruments at the Ready: Here is a List of "What Ifs" and "What to Do's"
20. The Surgical Tray for Cataract Surgery (Example)
21. Surgeon Specific Instruments
22. Self-Assessment Test Cataract Surgery
23. Surgical Checklist
24. Secondary IOLs
25. Corneal Surgery. The Cornea: How it Works
26. Corneal Transplantation: Penetrating Keratoplasty
27. Corneal Transplantation: Keratoprosthesis
28. Corneal Transplantation: Endothelial Keratoplasty/DSAEK
29. Corneal transplantation: Endothelial Keratoplasty/DMEK
30. Pterygium Surgery
31. Band Keratopathy Removal
32. Complications Encountered, Instruments at the Ready: Here is a list of "What ifs" and "What to dos
33. Surgical Tray Penetrating Keratoplasty
34. Surgical Tray Keratoprosthesis
35. Surgical Tray DSAEK
36. Surgical Tray DMEK
37. Surgical Tray Pterygium
38. Self Assessment Test Corneal Surgery.

Summary: This is a user-friendly, hands-on guide to literature searching, which is an essential skill for all involved in health care research and development, researchers, and students from all disciplines.

Contents:
Introduction
Where to Start
Clinical Information: Sources
Searching the Internet
Formulating Searchable Questions
Building a Search Strategy
Free Text and Thesaurus searching
Searching HealthCare Databases
Refining Search Results
Saving Citations
Citation Pearl Searching
Quality Improvement and Value: Sources
Patient Information: Sources
Critical Appraisal
Glossary of Terms
Appendix 1: Ten Tips for Effective Searching
Appendix 2: Teaching Resources
Record your Favourite Resources.

Summary: "Searching the Grey Literature is for librarians interested in learning more about grey literature. This book will help you tackle your search successfully, from start to finish. All types of librarians will find the content of this book useful, particularly those in health or social science"-- Provided by publisher.

Contents:
What is grey literature?
The value of grey literature
Databases for grey literature
Searching for dissertations/thesis
Searching for unpublished clinical trials
Repositories for grey lit
Conference proceedings, papers and posters for grey literature
Grey literature search checklists & other similar sources
Google for grey literature
Developing a grey literature search plan
Grey literature : keeping current with emerging trends and suggested learning tools.

Contents:
--sv. 2-5. [without special title].--s
v. 6. Disertace Purkyňových žáků.--s
v. 7. České práce fysiologické a morfologické.--s
v. 8. Úvahy a pracé přírodovědné.--s
v. 9. Věda, výchova, společnost, studie a úvahy.--s
v. 10. Slavistické pracé.--s
v. 11. Básně a překlady.--s
v. 12. Fysiologie lidské mluvy a menší fysiologickě pracé.--s
v. 13. Autobiografické stati. Bibliographia.

Summary: The engrossing memoir of a plastic and reconstructive surgeon involved in groundbreaking and life-changing procedures Through his work in plastic and reconstructive surgery, Dr. Donald Laub changed the lives of thousands of people who had been shunned by society. Dr. Laub's influence fostered the development of three key areas in the surgical profession: pioneering and influencing international humanitarian medical missions in the developing world, being at the forefront of gender affirmation surgery for transgender people since 1968, and the education and training of over 50 plastic and reconstructive surgeons. His unstinting efforts to surgically correct cleft palates gave new lives to thousands of children in developing countries. As one of the original surgeons to perform gender affirmation surgery, Laub not only continually improved on his methods, but he also became a tireless advocate for the rights of transgender people. His non-profit foundation (Interplast, now called ReSurge International) has sent thousands of multidisciplinary teams to perform transformative and reconstructive surgery in the developing world. Second Lives, Second Chances is more than just a memoir; it's a testament to how the determination of one person can bring others together to make a lasting difference in the world.

Contents:
Introduction to the Book
Objectives of secondary analysis of EHR data
Review of clinical database
Challenges and opportunities
Secondary Analysis of EHR Data Cookbook
Overview
Step 1: Formulate research question
Step 2: Data extraction and preprocessing
Step 3: Exploratory Analysis
Step 4: Data analysis
Step 5: Validation and sensitivity analysis
Missing Data
Noise vs. Outliers
Case Studies
Introduction
Predictive Modeling: outcome prediction (discrete)
Predictive Modeling: dose optimization (regression)
Pharmacovigilance (classification)
Comparative effectiveness: propensity score analysis
Comparative effectiveness: instrumental variable analysis
Decision and Cost Effectiveness Analysis: Hidden Markov models and Monte Carlo simulation
Time series analysis: Gaussian processes (ICP modelling)
Time series analysis: Bayesian inference (Motif discovery in numerical signals)
Time Series analysis: Optimization techniques for hyperparameter selection
Signal processing: analysis of waveform data
Signal processing: False alarm reduction.

Summary: This book offers an overview of the latest advances in the epidemiological, pathophysiological, diagnostic and therapeutic aspects of secondary hypertension, provided by a group of the most highly respected European experts in this field. It is common belief that secondary forms of hypertension are rare, although in 95% of patients the cause of high blood pressure is unknown - euphemistically referred to as "essential". There is increasing evidence from epidemiological studies that the prevalence of secondary hypertension is much higher than previously thought, accounting for 20%-25% of all hypertensive patients. There are additional, very good reasons for identifying those patients with secondary hypertension: firstly, they are exposed to a greater risk of suffering major cardiovascular events than patients with essential hypertension who have the same blood pressure level, and for this reason require particular care. Secondly, these patients can be relieved of a lifetime of pharmacological therapy or, at least, have a chance to be treated with more specific and effective medications. A high degree of clinical skill is required to recognize the often vague and subtle symptoms and signs that characterize patients with secondary hypertension, and clinicians need to fully comprehend the mechanisms responsible for the development and maintenance of high blood pressure. Shedding new light on a complex area of cardiovascular medicine, the book enables readers to better treat affected patients.

Contents:
Intro
Preface
Contents
Renal Parenchymal Disease
Introduction
Epidemiology
Pathophysiology of Hypertension in CKD
Hypertension as a Risk Factor for Kidney Function Loss in CKD
Special Conditions
Resistant Hypertension in CKD
Hypertension in Patients on Dialysis
Hypertension in Renal Transplant Patient
Antihypertensive Treatment and Target BP in CKD According to Recent Guidelines
Conclusion
References
Atherosclerotic Renovascular Disease
Introduction
Renal Artery Stenosis and Blood Pressure
Pathophysiological Mechanisms Clinical Significance of Renal Artery Stenosis
When and How to Search for Atherosclerotic Renal Artery Stenosis?
Treatment Issues
Conclusions
References
Fibromuscular Dysplasia: From a Rare Cause of Renovascular Hypertension to a More Frequent Systemic Arterial Disease
Introduction
Definition of FMD
Differential Diagnosis
Classification
Possible Manifestations
Stenosis
Dissections
Aneurysms
Arterial Tortuosity
Aetiological Factors
Genetics
Focus on Renal FMD
What Is the Prevalence of Renal FMD?
In the General Population? In Hypertensive Patients?
What Is the Profile of Patients with Renal FMD?
In Whom to Screen for Renal FMD?
What Is the Best Screening and Diagnostic Strategy?
What Are the Essential Steps to Consider in the Management/Work-Up of Renal FMD?
Has Smoking an Influence on FMD?
Which Medical Treatment in the Patient with FMD?
How to Assess Haemodynamic Significance of FMD-Related Renal Artery Stenosis?
Whom to Revascularize?
How to Revascularize?
Is FMD a Systemic Disease?
Which Usual Work-Up in Patients with Renal Artery FMD?
When to Look for Familial FMD? How to Prepare Pregnancy in a Patient with FMD?
Can FMD Affect the Heart?
Are There Specificities of FMD in Elderly Patients?
Are There Specificities of FMD in Children?
Is FMD a Progressive Disease?
Which Follow-Up in Patients with Renal Artery FMD?
Conclusion
References
Primary Aldosteronism
Introduction
Detection Rate and Screening Strategy
Diagnosis
Conditions for Testing
Exclusion of Primary Aldosteronism
Imaging
Subtyping of Primary Aldosteronism
Adrenal Vein Sampling
Alternative Strategy for Subtyping
Genetic Testing
Treatment

Contents:
Intro
Foreword
Acknowledgments
Contents
Introduction
Part I: General Theory of Secondary Hypertension
1: Summary of Secondary Hypertension
1.1 Screening for Secondary Hypertension
1.1.1 Prevalence of Secondary Hypertension
1.1.2 Preliminary Screening of Secondary Hypertension
1.1.3 Specialized Examination of Secondary Hypertension
1.1.4 Screening Process for Secondary Hypertension
1.2 Resistant Hypertension
1.2.1 Prevalence and Diagnostic Criteria of RH:
1.2.2 Precautions for the Diagnosis of RH and Pseudo RH 1.2.3 Screening of Secondary Hypertension in Patients with RH:
1.2.4 Management of RH
1.2.5 Recommended Hypertension Specialist Visit
1.2.6 Invasive Interventional Therapy
References
2: Clinical Manifestations of Secondary Hypertension: Medical History, Symptom Characteristics, and Signs
2.1 History Taking
2.2 Characteristics of Symptoms
2.3 Common Characteristics in Secondary Hypertension
2.4 Physical Examination
2.5 Relationship Between Secondary Hypertension and Age 2.6 Characteristics of Different Types of Secondary Hypertension History and Physical Examination
References
3: Significance of General Laboratory Examination in the Diagnosis of Secondary Hypertension
3.1 Routine Laboratory Blood Tests
3.1.1 Blood Routine
3.1.1.1 Red Blood Cells
3.1.1.2 White Blood Cells
3.1.1.3 Platelets
3.1.2 Serum Potassium
3.1.2.1 Hypokalemia (K+ 5.3 mmol/L)
3.1.3 Blood Glucose
3.1.4 Blood Lipids
3.1.5 Serum Uric Acid
3.1.6 Hypersensitive C-Reactive Protein (CRP) 3.1.7 Plasma Insulin Levels
3.1.8 Renal Function
3.1.9 Homocysteine (Hcy)
3.2 Urine Examination
3.2.1 Examination of General Traits
3.2.1.1 Urine Volume
3.2.1.2 Color and Transparency
3.2.1.3 Foam
3.2.1.4 Urine Specific Gravity (SG)
3.2.1.5 Urinary PH Value
3.2.2 Detection of Urinary Protein and Urinary Microalbumin
3.2.2.1 Proteinuria Standards (Table 3.4)
3.2.2.2 Clinical Significance of Proteinuria
3.2.3 Urine Red Blood Cells or Occult Blood
3.3 Hemorheology
3.3.1 Hemorheology and Hypertension 3.3.1.1 Hemorheological Characteristics of Obstructive Sleep Apnea Hypopnea Syndrome (OSAHS)
3.3.1.2 Hemorheological Characteristics of Pregnancy-Induced Hypertension Syndrome
3.3.1.3 Hemorheological Characteristics of Essential Hypertension
3.4 Ambulatory Blood Pressure and Exercise Blood Pressure
3.4.1 Ambulatory Blood Pressure
3.4.1.1 Application of ABPM in Renal Hypertension
3.4.1.2 ABPM and Primary Aldosteronism
3.4.1.3 ABPM and Pheochromocytoma
3.4.1.4 ABPM and Sleep apnea syndrome
3.4.1.5 ABPM in the Elderly
3.4.1.6 ABPM for Adolescents

Summary: Recent changes in the pattern of agricultural practices from use of hazardous pesticides to natural (organic) cultivation has brought into focus the use of agriculturally important microorganisms for carrying out analogous functions. The reputation of plant growth promoting rhizomicroorganisms (PGPRs) is due to their antagonistic mechanisms against most of the fungal and bacterial phytopathogens. The biocontrol potential of agriculturally important microorganisms is mostly attributed to their bioactive secondary metabolites. However, low shelf life of many potential agriculturally important microorganisms impairs their use in agriculture and adoption by farmers. The focal theme of this book is to highlight the potential of employing biosynthesized secondary metabolites (SMs) from agriculturally important microorganisms for management of notorious phytopathogens, as a substitute of the currently available whole organism formulations and also as alternatives to hazardous synthetic pesticides. Accordingly, we have incorporated a comprehensive rundown of sections which particularly examine the SMs synthesized, secreted and induced by various agriculturally important microorganisms and their applications in agriculture. Section 1 includes discussion on biosynthesized antimicrobial secondary metabolites from fungal biocontrol agents. This section will cover the various issues such as development of formulation of secondary metabolites, genomic basis of metabolic diversity, metabolomic profiling of fungal biocontrol agents, novel classes of antimicrobial peptides. The section 1 will also cover the role of these secondary metabolites in antagonist-host interaction and application of biosynthesized antimicrobial secondary metabolites for management of plant diseases. Section 2 will discuss the biosynthesized secondary metabolites from bacterial PGPRs, strain dependent effects on plant metabolome profile, bio-prospecting various isolates of bacterial PGPRs for potential secondary metabolites and non-target effects of PGPR on microbial community structure and functions. Section 3 encompasses synthesis of antimicrobial secondary metabolites from beneficial endophytes, bio-prospecting medicinal and aromatic hosts and effect of endophytic SMs on plants under biotic and biotic stress conditions.

Contents:
Bioactive secondary metabolites of basidiomycetes and its potential for agricultural plant growth promotion
Secondary metabolites of Metarhizium spp. and Verticillium spp. and their agricultural applications
Secondary Metabolites of nonpathogenic Fusarium spp.: Scope in agriculture
Non-mycorrhizal fungal spectum of root communities
Bioactive Volatile Secondary Metabolites of Trichoderma spp.: Future Perspectives
Phytopathogen biomass as inducer of antifungal compounds by Trichoderma asperellum under solid-state fermentation
Bioactive Secondary metabolites of Trichoderma spp. for efficient management of phytopathogens
Secondary metabolites of the plant growth promoting model rhizobacterium Bacillus velezensis FZB42 are involved in direct suppression of plant pathogens and in stimulation of plant induced systemic resistance
Pyrroloquinoline quinone (PQQ): Role in bacteria-plant interactions
Bacterial mechanisms promoting the tolerance against drought stress in plants
Bacillus spp. as plant growth promoting rhizobacteria
Secondary Metabolites from Cynobacteria: A potential source for plant growth promotion and disease management
Biological control of nematodes by Plant Growth Promoting Rhizobacteria: secondary metabolites involved and potential applications
A deeper insight into the symbiotic mechanism of Rhizobium spp. from the perspective of secondary metabolism
Metabolites of Plant Growth Promoting Rhizobacteria for the Management of Soil Borne Pathogenic Fungi in Crops
Exploiting of beneficial endophytic microorganisms in plant growth promotion and crop protection: Elucidation of some bioactive secondary metabolites involved in both effects
Bioprocessing of endophytes for production of high value biochemical
Synthesis and application of hydroxamic acid: A key secondary Metabolite of Piriformospora indica.

Summary: Open heart surgery has been in a continuous state of evolution since its earliest day. This book presents information on the management of secondary mitral valve regurgitation, one of most vexing problems to cardiologists, cardiac surgeons and patients. The treatment for primary mitral regurgitation is straightforward and has as its primary aim timely intervention to prevent left ventricular remodelling and left ventricular dysfunction. The management of secondary mitral regurgitation is more challenging as the mitral valve is not the primary cause of the disease. Furthermore, correcting mitral regurgitation without changing the left ventricular geometry is not guaranteed to be either beneficial or curative. Secondary Mitral Valve Regurgitation draws together contributions from a range of experienced cardiac surgeons, cardiologists, anesthetists and scientists to provide comprehensive and authoritative coverage on anatomy, hemodynamics, mechanism, echocardiographic assessment and treatment modalities. Many of the elusive details surrounding the best management of secondary mitral regurgitation are presented in a comprehensive manner so that this book will serve as an important primary source for readers wanting information on this important topic.

Summary: In the natural course of events, humans fall sick and die. The history of medicine bristles with attempts to find new and miraculous remedies, to work with and against nature to restore humans to health and well-being. In this book, Londa Schiebinger examines medicine and human experimentation in the Atlantic World, exploring the circulation of people, disease, plants, and knowledge between Europe, Africa, and the Americas. She traces the development of a colonial medical complex from the 1760s, when a robust experimental culture emerged in the British and French West Indies, to the early 1800s, when debates raged about banning the slave trade and, eventually, slavery itself. Massive mortality among enslaved Africans and European planters, soldiers, and sailors fueled the search for new healing techniques. Amerindian, African, and European knowledges competed to cure diseases emerging from the collision of peoples on newly established, often poorly supplied, plantations. But not all knowledge was equal. Highlighting the violence and fear endemic to colonial struggles, Schiebinger explores aspects of African medicine that were not put to the test, such as Obeah and vodou. This book analyzes how and why specific knowledges were blocked, discredited, or held secret.

Contents:
The rise of scientific medicine
Experiments with the Negro Dr's materia medica
Medical ethics
Exploitive experiments
The colonial crucible : debates over slavery
Conclusion : the circulation of knowledge.

Summary: "This thought-provoking, compact designer's guide helps you understand how maps are a part of our everyday thinking, how they organize data, and how they can reframe our point of view"-- Provided by publisher. "Maps aren't just geographic, they are also infographic and include all types of frameworks and diagrams. Any figure that sorts data visually and presents it spatially is a map. Maps are ways of organizing information and figuring out what's important. Even stories can be mapped! The Secret Language of Maps provides a simple framework to deconstruct existing maps and then shows you how to create your own. An embedded mystery story about a woman who investigates the disappearance of an old high school friend illustrates how to use different maps to make sense of all types of information. Colorful illustrations bring the story to life and demonstrate how the fictional character's collection of data, properly organized and "mapped," leads her to solve the mystery of her friend's disappearance. You'll learn how to gather data, organize it, and present it to an audience. You'll also learn how to view the many maps that swirl around our daily lives with a critical eye, aware of the forces that are in play for every creator." -- Publisher's description

Contents:
Part 1. The investigation. What is a map?
Looks matter / Craft deconstruction
Mind the message / Bias deconstruction
The D word / Data deconstruction
Part 2. The expose. How to make a map?
Knead the dough / Data exploration
Agendas are for everyone / Bias exploration
Shape shift / Craft exploration
Explain all day
Endnotes
Acknowledgments
Index.

Summary: "A sure grasp of cross-sectional anatomy is essential for accurate radiologic interpretation, and Sectional Anatomy by MRI and CT, 5th Edition, provides exactly the information needed in a highly illustrated, quick-reference format. New coverage of the cervical spine, brain, and thumb, as well as new on/off labels in the eBook version make this title an essential diagnostic tool for both residents and practicing radiologists." -- Elsevier website

Contents:
CT of the brain
MRI of the brain
CT of the thorax
MRI of the heart
MRI of the pectoral girdle and chest wall
MRI of the shoulder
MR arthrography of the shoulder
MRI of the arm
MRI of the elbow
MRI of the forearm
MRI of the wrist
MRI of the hand
MRI of the cervical spine
MRI of the thoracic spine
MRI of the lumbar spine
CT of the abdomen
MRI of the abdomen
MRI of the hip
MR arthrography of the hip
MRI of the thigh
MRI of the knee
MRI of the leg
MRI of the ankle
MRI of the foot
CT of the male pelvis
CT of the female pelvis
MRI of the male pelvis
MRI of the female pelvis.

Contents:
Sedation in dentistry: a historic perspective
Pain and anxiety in dentistry
Introduction to sedation
The spectrum of pain and anxiety control
Physical and psychological evaluation
Monitoring during sedation
Nondrug techniques : iatrosedation and hypnosis
Oral sedation
Rectal sedation
Sublingual, transdermal, and intranasal sedation
Intramuscular sedation
Inhalation sedation : historical perspective
Inhalation sedation : rationale
Pharmacology, anatomy, and physiology
Inhalation sedation equipment
Inhalation sedation : techniques of administration
Inhalation sedation : complications
Contemporary issues surrounding nitrous oxide
Practical considerations
Teaching inhalation sedation : history and present guidelines
Intravenous sedation : historical perspective
Intravenous moderate sedation : rationale
Armamentarium
Anatomy for venipuncture
Venipuncture technique
Pharmacology
Intravenous moderate sedation : techniques of administration
Intravenous sedation : complications
Practical considerations
Guidelines for teaching
Fundamentals of general anesthesia
Armamentarium, drugs, and techniques
Preparation for emergencies
Emergency drugs and equipment
Management of emergencies
The pediatric patient
The geriatric patient
The medically compromised patient
The physically compromised patient
Neurologic illnesses and other conditions
Medicolegal considerations
The controversial development of anesthesiology in dentistry.

Summary: This book provides a comprehensive overview on sedation and analgesia for the pediatric intensivist. Divided into two primary sections, the text presents a framework on how to care for patients who need sedation, analgesia, and neuromuscular blockade inside the pediatric ICU (PICU), and how to manage procedural sedation in an outpatient setting. The first section focuses on sedation and analgesia for the critically ill child, with an emphasis on analgesics, sedatives, neuromuscular blockade, tolerance and withdrawal, and the PICU environment. The second section centers around procedural sedation, detailing patient selection, pre-sedation assessment, how to choose a sedation regimen, available agents, and nursing considerations. Written by experts in the field, Sedation and Analgesia for the Pediatric Intensivist: A Clinical Guide is a valuable resource for the pediatric intensivist in caring for their patients both inside and outside the PICU.

Contents:
Intro
Foreword
Preface
Contents
Contributors
Part I: Sedation and Analgesia for the Critically Ill Child
Chapter 1: Introduction to Sedation and Analgesia
Brief History of Pediatric Sedation and Analgesia
Goal of Sedation and Analgesia in the Critically Ill Child
Physiology of Pain
Complexities of Sedation and Analgesia in the Critically Ill Child
References
Chapter 2: Safety and Monitoring During Pediatric ICU Sedation
Assessment Tools
Pain Assessment
Self-Report Tools and Surrogate Reporting
Observational Tools Agitation and Sedation Assessment
Objective Monitoring Tools
Processed EEG
Conventional EEG
Conclusions
References
Chapter 3: Analgesic Use in the Pediatric Intensive Care Unit
Specific Agents
References
Chapter 4: Regional Analgesia and Its Role in the PICU
Introduction
History
Safety and Risks of Regional Anesthesia
Benefits of Regional Anesthesia
Some Common Blocks
Central Neuraxial Blocks
Upper Extremity Blocks
Truncal Blocks
Lower Extremity Blocks
Conclusion
References
Part II: Sedative Agents Chapter 5: Sedative Agents (Benzodiazepines)
Overview of Benzodiazepines and Mechanism of Action
Pharmacokinetic and Pharmacodynamic Considerations
Adverse Reactions, Drug-Drug Interactions, and Monitoring Parameters
Benzodiazepine and Opioids
Breastfeeding/Pregnancy Considerations
Pregnancy Considerations
Breastfeeding Considerations
In Summary
References
Chapter 6: Alpha-Agonists in Pediatric Critical Care
Introduction
Pharmacology
Clinical Applications
Conclusion
References
Chapter 7: Barbiturates in the Pediatric ICU
Introduction Pharmacology
Clinical Applications
References
Part III: Anesthetic Agents
Chapter 8: Sedation and Analgesia for the Critically Ill Child: Ketamine
Introduction
Pharmacokinetics and Pharmacodynamics
Mechanism of Action
Dosing
Uses of Ketamine in the Pediatric Intensive Care Unit
Ketamine for Sedation
Ketamine for Acute Pain
Ketamine for Chronic Pain
Ketamine Side Effects
Conclusion
References
Chapter 9: Propofol for Sedation of the Critically Ill Child
Introduction
Pharmacology
Mechanism of Action
Pharmacokinetics
Pharmacodynamics Clinical Considerations for Use
Indications for Short-Term, Deep Sedation
Propofol "Drug Washout"
The Impact of Propofol on Sleep and Delirium in ICU Patients
Palliative Sedation
Propofol-Related Infusion Syndrome (PRIS)
Pathophysiology
Prevention and Treatment
Consideration in Special Populations
Mitochondrial and Metabolic Disorders
Conclusions
Bibliography
Chapter 10: Inhalational Agents: What Volatile Inhalational Agents Are and How to Use Them in the ICU Setting
Introduction
Principles of Inhalational Agents
Minimum Alveolar Concentration

Summary: The global population is increasing rapidly, and feeding the ever-increasing population poses a serious challenge for agriculturalists around the world. Seed is a basic and critical input in agriculture to ensure global food security. Roughly 90 percent of the crops grown all over the world are propagated by seed. However, seed can also harbour and spread pathogens, e.g. fungi, bacteria, nematodes, viruses etc., which cause devastating diseases. Seed-borne pathogens represent a major threat to crop establishment and yield. Hence, timely detection and diagnosis is a prerequisite for their effective management. The book "Seed-Borne Diseases of Agricultural Crops: Detection, Diagnosis & Management" addresses key issues related to seed-borne/transmitted diseases in various agricultural crops. Divided into 31 chapters, it offers a comprehensive compilation of papers concerning: the history of seed pathology, importance of seed-borne diseases, seed-borne diseases and quarantine, seed health testing and certification, detection and diagnosis of seed-borne diseases and their phytopathogens, host-parasite interactions during development of seed-borne diseases, diversity of seed-borne pathogens, seed-borne diseases in major agricultural crops, non-parasitic seed disorders, mechanisms of seed transmission and seed infection, storage fungi and mycotoxins, impact of seed-borne diseases on human and animal health, and management options for seed-borne diseases. We wish to thank all of the eminent researchers who contributed valuable chapters to our book, which will be immensely useful for students, researchers, academics, and all those involved in various agro-industries.

Contents:
Part 1. Impact of seed borne phytopathogens or seed borne diseases on agriculture and society
Chapter 1. Importance of Seed-borne Diseases of Agricultural Crops: Economic losses and Impact on Society
Chapter 2. Major Seed-borne Diseases of Agricultural Crops: International Trade of Agricultural Products and Role of Quarantine
Part II. History of seed pathology
Chapter 3. Contribution of Individuals and Organizations in the Development of Seed Pathology
Chapter 4. Ancient, Mid-time and Recent History of Seed Pathology
Part III. Diagnosis & detection of seed borne pathogens
Chapter 5. Diagnosis and detection of Seed borne fungal phytopathogens
Chapter 6. Detection of Seed and Propagating Material Borne Bacterial Diseases of Economically Important Crops
Chapter 7. Detection and diagnosis of seed-borne viruses and virus like pathogens
Chapter 8. Detection and diagnosis of seed borne and seed associated nematode
Part IV. Host
parasite interaction during the development of seed borne diseases
Chapter 9. Host-parasite Interaction During Development of Major Seed-borne Fungal Diseases
Chapter 10. Host-parasite interaction during development of major seed borne bacterial diseases
Chapter 11. Host-parasite interaction during development of major seed transmitted viral diseases
Chapter 12. Host-parasite interaction during development of major seed borne diseases caused by nematodes
Part V. Diversity of seed borne phytopathogens
Chapter 13. Diversity of seed borne fungal phytopathogens
Chapter 14. Diversity of seed borne bacterial phytopathogens
Chapter 15. Genetic diversity, transmission and understanding of seed-borne viruses and phytoplasma
Chapter 16. Diversity of Seed Borne and Seed Associated Nematodes
Part VI. Major Seed borne diseases in different agricultural crops
Chapter 17. Major Seed borne diseases in important cereals: Symptomatology, etiology & economic importance
Chapter 18. Major Seed born e diseases in important oilseeds: Symptomatology, etiology & economic importance
Chapter 19. Major Seed borne diseases in important pulses: Symptomatology, etiology & economic importance
Chapter 20. Major Seed borne diseases in important vegetables: Symptomatology, etiology & economic importance
Chapter 21. Major Seed borne diseases in important forage crops & fibre crops: Symptomatology, etiology & economic importance
Part VII. Seed borne diseases: Human and animal health
Chapter 22. Seed borne diseases: its impact on Human and animal health
Part VIII. Management of seed borne pathogens/diseases
Chapter 23. Use of Biological Control Agents in the Management of Seedborne Diseases
Chapter 24. Chemical Management of seed borne diseases: Achievements and future challenges
Chapter 25. Biotechnology: An intervention for the genetic resistance against seed borne phytopathogens
Chapter 26. Management of Seed borne diseases: An integrated approach
Part IX: Mechanism of seed transmission and seed infection
Chapter 27. Mechanism of Seed Transmission and Seed Infection in Major Agricultural Crops in India
Part X: Miscellaneous
Chapter 28. Seed Health Testing and Seed Certification
Chapter 29. Non-Parasitic Seed Disorders of Major Agricultural Crops
Chapter 30. Storage fungi and Mycotoxins
Chapter 31. Epidemiology of seed borne diseases.

Summary: This book focuses on the importance and roles of seed microbiomes in sustainable agriculture by exploring the diversity of microbes vectored on and within seeds of both cultivated and non-cultivated plants. It provides essential insights into how seeds can be adapted to enhance microbiome vectoring, how damaged seed microbiomes can be assembled again and how seed microbiomes can be conserved. Plant seeds carry not only embryos and nutrients to fuel early seedling growth, but also microbes that modulate development, soil nutrient acquisition, and defense against pathogens and other stressors. Many of these microbes (bacteria and fungi) become endophytic, entering into the tissues of plants, and typically exist within plants without inducing negative effects. Although they have been reported in all plants examined to date, the extent to which plants rely on seed vectored microbiomes to enhance seedling competitiveness and survival is largely unappreciated. How microbes function to increase the fitness of seedlings is also little understood. The book is a unique and important resource for researchers and students in microbial ecology and biotechnology. Further, it appeals to applied academic and industrial agriculturists interested in increasing crop health and yield.

Contents:
Intro; Prologue; What Are Endophytes?; A New Definition for Seeds: A Miniature 'Noah's Ark' for Plant Colonization; The Intention of This Book; Contents; Part I: Seed Endophytes: Introduction, and Methods for Assessment and Management;
1: Seed-Vectored Microbes: Their Roles in Improving Seedling Fitness and Competitor Plant Suppression; 1.1 The Seed Microbiome; 1.2 Adaptations of Seeds to Carry Symbiotic Microbes; 1.3 Roles of Seed-Vectored Microbes in Plant Seedlings; 1.4 What Happens to Seed-Vectored Microbes?; 1.5 Signal Molecules; 1.6 Endobiome Interference 1.7 Mode of Entry of Micrococcus luteus into Root Cells1.8 Intracellular Phases of Aureobasidium pullulans and Rhodotorula sp.; 1.9 Does Endobiome Interference Affect Plant-Plant Interactions?; 1.10 Potential Applications of Endobiome Interference to Control Invasive or Weedy Plant Species; 1.11 Conclusions; References;
2: Thinking About PPFM Bacteria as a Model of Seed Endophytes: Who Are They? Where Did They Come from? What Are They Doing for ... ; 2.1 Fooled by a Bacterium; 2.2 Recognizing the Significant Role of Bacteria in Plant Metabolism 2.3 Looking at Seed Endophytes Through a Pink-Pigmented Facultatively Methylotrophic Lens2.3.1 So Where Does This Relationship Come from?; 2.3.2 What Are They Doing for Seeds?; 2.3.3 What Are They Doing for the Plants?; 2.3.4 A Role for Seed Endophytes in Plant Improvement; 2.3.5 As an Aside: Endophytes Influence the Quality of Seeds as Food Items for Us; 2.4 Outstanding Questions; 2.5 Conclusions; References;
3: Seed Endophytes and Their Potential Applications; 3.1 Background; 3.2 Seed Endophytes; 3.3 Assessing Seed Endophytic Communities; 3.4 Roles of Seed-Borne Endophytes 3.4.1 Seed Endophytes and Plant Growth Enhancement3.4.2 Seed Endophytes Mitigating Heavy Metal Toxicity/Stress; 3.5 Mechanism of the Growth Promotion and Heavy Metal Stress Tolerance; 3.5.1 Heavy Metal Resistance Genes Conferring Metal Resistance; 3.6 Future Prospects; References;
4: Exploring Endophytic Communities of Plants: Methods for Assessing Diversity, Effects on Host Development and Potential Biot ... ; 4.1 Introduction; 4.1.1 What Are Endophytes?; 4.1.2 Challenges in the Study of Endophytes; 4.2 Isolation of Endophytic Microbes; 4.2.1 Media for Isolation of Fungal Endophytes 4.2.2 Media for Isolation of Bacterial Endophytes4.3 Identification of Endophytes; 4.3.1 Molecular Tools to Identify Endophytes; 4.3.2 Markers and Primers for Endophyte Identification; 4.4 Techniques to Evaluate Endophyte Distribution in Plants; 4.4.1 Hood and Shew Staining Protocol; 4.4.2 Fluorescent Probes for Localization of Bacterial and Fungal Endophytes; 4.4.3 ROS Staining to Study Bacterial Endophytes; 4.5 Endophyte Modulation of Seedling Development; 4.5.1 Examining Modulation of Seedling Development Where Endophytes Are Not Culturable

Summary: "By the end of the seventeenth century, explorers had circled the globe and mapped the heavens. Scientists had calculated the weight of the Earth, traced the paths of comets, and divined the secrets of the Milky Way. But at the dawn of the modern age, the deeper scientific riddle of all lay unsolved: Where do babies come from? Throughout most of human history, babies were surprises. People knew the basics: men and women had sex, and sometimes babies followed. But beyond that, the origins of life were a colossal mystery--a mystery that would take centuries of wild theories, misogynist blunders, and mistakes to solve. The author investigates the early scientists who sought answers. The author's investigation careens from theaters of anatomy, where spectators gawked at dissected bodies; to princes' private museums; to a seaside laboratory in Naples, Italy where a researcher peered into his microscope and first witnessed the union of sperm and egg. The author also introduces a Danish physician who began by studying sharks' teeth and ended by finding the secret of human eggs. Another researcher, who was a Catholic priest, outfitted male frogs in tiny boxer shorts to prove that semen had to touch eggs to fertilize them. This book presents our greatest scientists struggling--against their perceptions, their religious beliefs, and their deep-seated prejudices--to uncover the deepest mysteries of life"--Book cover.

Contents:
Prologue: England in the early 1630s
Peering Into the Body. Onward to glory ; Hidden in deep night ; Swallowing stones and drinking dew ; Unmoored in time ; "Double, double toil and trouble" ; Door A or door B?
The Search for the Egg. Missing : one universe (reward to finder) ; Sharks' teeth and cows' eggs ; The egg, at last ; A world in a drop of water ; "Animals of the semen"
Russian Dolls. Dolls within dolls ; The message in God's fine print ; Sea of troubles ; The rabbit woman of Godliman ; "All in pieces, all coherence gone" ; The cathedral that built itself ; A vase in silhouette
The Clockwork Topples and a New Theory Rises. Frogs in silk pants ; A drop of venom ; The craze of the century ; "I saw the dull yellow eye of the creature open" ; The nose of the Sphinx ; "The game is afoot" ; Caught!

Contents:
Intro; Foreword; Table of contents; Abstract; List of figures; List of tables; List of abbreviations; 1 Introduction; 1.1 Research context and problem statement; 1.2 Research objective; 1.3 Structure of the thesis; 2 Theoretical background; 2.1 Disruptive innovation concept; 2.1.1 Terminology and conceptualization of disruptive innovation; 2.1.2 The role of business models in disruptive innovation; 2.2 Business model concept; 2.2.1 Conceptualization of business models; 2.2.2 Business model as an activity system; 2.3 Business model innovation concept 2.3.1 Conceptualization and classification of business model innovation2.3.2 Business model innovation as a process vs. outcome; 2.3.3 Artifacts for business model innovation; 2.4 Synopsis and research question; 3 Design science research; 3.1 Overall research design; 3.1.1 Research paradigm; 3.1.2 Research method; 3.2 Exploratory research design; 3.2.1 Exploratory research method; 3.2.2 Sampling; 3.2.3 Data collection and preparation; 3.2.4 Data analysis; 4 Results and discussion of exploratory research; 4.1 Results; 4.1.1 Descriptive analysis; 4.1.2 Content analysis 4.1.2.1 Problem identification and objective of a solution4.1.2.2 Business model patterns for disruptive innovations; 4.2 Discussion; 4.2.1 Purpose and scope; 4.2.2 Justificatory knowledge; 4.2.3 Principles of form and function; 5 Prescriptive research design; 5.1 Design construction; 5.1.1 Design as a search process; 5.1.2 Design as an artifact; 5.2 Design evaluation; 5.2.1 Design evaluation method; 5.2.2 Sampling; 5.2.3 Data collection and preparation; 5.2.4 Data analysis; 5.2.5 Role of the researcher; 6 Results and discussion of prescriptive research; 6.1 Results 6.1.1 Design construction: low-resolution artifact6.1.2 Design evaluation; 6.1.3 Design (re)construction and communication; 6.2 Discussion; 6.2.1 Principles of implementation; 6.2.2 Testable propositions; 6.2.3 Constructs and expository instantiation; 6.2.4 Artifact mutability; 7 Conclusion; 7.1 Contribution; 7.1.1 Contribution to theory; 7.1.2 Contribution to practice; 7.1.3 Contribution to methodology; 7.2 Limitations; 7.3 Further research; 7.4 Concluding remarks; References; Appendices;
Appendix 1: Coding structure;
Appendix 2: Pattern matrix
Appendix 3: HMW brainstorming questions on problems organizations encounter when designing business models for disruption
Appendix 4: Decision matrix for ideation stage;
Appendix 5: Design Thinking evaluation workshop, Minutes;
Appendix 6: Elements of the Design Theory for BMI in the context of DI

Contents:
Chapter 1- Epidemiology of Seizures and Epilepsy in Cerebrovascular Disease
Chapter 2: Seizures in Ischemic Stroke
Chapter 3: Seizures in Intracerebral Hemorrhage
Chapter 4: Seizures in Subarachnoid Hemorrhage
Chapter 5: Seizures in subdural hematoma
Chapter 6: Seizures in Cerebral Cavernous Malformations
Chapter 7: Seizures in Arteriovenous Malformations
Chapter 8: Seizures in Cerebral Venous Sinus Thrombosis
Chapter 9: Pediatric Stroke and Seizures
Chapter 10: Medical Management of Seizures in Cerebrovascular Disorders.

Summary: Updated and expanded to provide the neurologic, intensive and critical care communities a comprehensive guide to common critical care illnesses and seizures, this third edition remains the premier resource on seizures in critical care. In addition to covering etiology, pathophysiology, diagnosis, differential diagnosis and treatment options, chapters feature the latest technologies and treatments and integrate current literature. This unique and specialized text offers neurologists, intensivists, neurosurgeons, trauma surgeons, epileptologists, electrophysiologists and residents in various specialties clarity on this challenging set of comorbidities.

Contents:
Part I. General section. Chapter 1: Status epilepticus - lessons and challenges from animal models ; Chapter 2: Impact of seizures on outcome ; Chapter 3: Diagnosing and monitoring seizures in the ICU: the role of continuous EEG for detection and management of seizures in critically ill patients, including the ictal-interictal continuum ; Chapter 4: Seizures and quantitative EEG ; Chapter 5: Spreading depolarizations and seizures in clinical subdural electrocorticographic recordings ; Chapter 6: Multimodality monitoring correlates of seizures ; Chapter 7: Management of critical care seizures ; Chapter 8: Management of status epilepticus in the inensive care unit.
Part II. Etiology-specific section. Chapter 9: Ischemic stroke, hyperperfusion syndrome, cerebral sinus thrombosis, and critical care seizures ; Chapter 10: Hemorrhagic stroke and critical care seizures ; Chapter 11: Traumatic brain injury and critical care seizures ; Chapter 12: Brain tumors and critical care seizures ; Chapter 13: Global hypoxia-ischemia and critical care seizures ; Chapter 14: Fulminant hepatic failure, multiorgan failure and endocrine crisis and critical care seizures ; Chapter 15: Organ transplant recipients and critical care seizures ; Chapter 16: Extreme hypertension, eclampsia, and critical care seizures ; Chapter 17: Infection or inflammation and critical care seizures ; Chapter 18: Electrolyte disturbances and critical care seizures ; Chapter 19: Alcohol-related seizures in the intensive care unit ; Chapter 20: Drug-induced seizures in critically ill patients ; Chapter 21 : Illicit drugs and toxins and critical care seizures ; Chapter 22: Seizures and status epilepticus in pediatric critical care.

Summary: Selected References in Trauma and Orthopaedics provides a selection of references from the Trauma and Orthopedic literature, aimed at the surgeon preparing for the Intercollegiate Specialty Board examination, and similar end-of training examinations in other countries. It is the perfect guide for examiners and trainers who are preparing their trainees for the examination, as well as providing a literature basis for their own practice. Selected References in Trauma and Orthopaedics presents the classical papers underlying current practice as well as recent publications which have brought about innovation, clarified pathology or demonstrated outcomes. The references are presented with a brief summary which allows the reader to access a literature review, with the use of online resources, with the key references already identified.

Contents:
Part I. Adult Elective Orthopaedics
Part II. Trauma
Part III. Children's Orthopaedics
Part IV. Hand and Upper Limb.

Summary: This book explains the basic concepts of Selective Decontamination of the Digestive tract (SDD) to help those involved in treating critically ill patients to improve outcomes and the quality of care. SDD has led to major changes in our understanding, the treatment and prevention of infections in critically ill patients over the past 40 years. It is the most studied intervention in intensive care medicine and is the subject of 73 randomized controlled trials, including over 15000 patients and 15 meta-analyses. SDD reduces morbidity and mortality, is cost-effective and safe as SDD does not increase antimicrobial resistance. Correct application of the SDD strategy enables ICU teams to control infections - even in ICUs with endemic antibiotic resistant microorganisms such as methicillin resistant S. aureus (MRSA). Describing the concept and application of SDD, and presenting case studies and microbiological flow charts, this practical guide will appeal to intensivists, critical care practitioners, junior doctors, microbiologists and ICU-nurses as well as infection control specialists and pharmacists.

Contents:
Part I. The basics
Introduction
Microorganisms
Defense
Infections
Infection control
Enteral and parenteral antimicrobials used in the SDD-policy
Part II. Clinical microbiology for the ICU team
Clinical microbiology: an overview
Surveillance versus diagnostic cultures
Sampling and microscopy
Inoculation and culturing
Naming of microorganisms
Antibiotic sensitivity testing
Availability of the clinical microbiological results for the intensivist
Part III. Therapeutics
Therapy of bacterial and fungal infections
Viral infections in the ICU
Inflammation and hyperinflammation
Part IV. Surveillance
Resistance
Outbreaks
Appendix
Appendix 1. General principles before implementing the SDD-strategy
Appendix 2. Selective decontamination of the digestive tract
Appendix 3. SDD in Methicillin-resistant S. aureus (MRSA)
Appendix 4. SDD in Multidrug-resistant Gram-negative bacteria (MDRGNB).

Contents:
1. The epidemiology of selenium and human cancer
2. Selenoproteins in tumorigenesis and cancer progression
3. Selenoproteins and metastasis
4. Selenium-dependent glutathione peroxidases during tumor development
5. Targeting the selenoprotein thioredoxin reductase 1 for anticancer therapy
6. The regulation of pathways of inflammation and resolution in immune cells and cancer stem cells by selenium
7. Selenium and breast cancer risk: focus on cellular and molecular mechanisms
8. Selenium and epigenetics in cancer: focus on DNA methylation
9. Selenium and cancer stem cells
10. Selenocompounds in cancer therapy: an overview.

Summary: Selenium plays a significant role in preventing certain types of cancer and cardiovascular diseases. The level of Selenium in the human body depends on its concentration in food. In turn, the content in vegetable crops is a function of the soil-plant system. There are many countries in the world with low Selenium content in the soil. The average daily human intake is thus limited through food chain. Analysis of Selenium status suggests that fortification of the soil substrate with Sodium Selenate, and foliar application to agricultural crops are both effective means of Selenium enrichment. Our intention for this publication is to present the possibilities of augmenting Selenium content by biofortification of soils and plants through differentiated nutrition. In the first part of the monograph, the results of Selenium supplementation in model vegetation experiments are presented. The next part of the monograph presents the results of foliar supplementation of Selenium in field conditions. This book is an outstanding reference source for plant breeders and researchers engaged in biofortification of horticulture crops. It is also beneficial to agricultural companies and other stakeholders.

Contents:
Introduction
The role of selenium in human nutrition
Methods for determination of selenium in foodstuffs
Selenium uptake by selected vegetable species after fortification of the growing substrate.-Selenium uptake by selected vegetable species after foliar application
Changes of selenium content in edibilities during the processing.

Contents:
Examining xCT-mediated selenium uptake and selenoprotein production capacity in cells / Namgyu Lee, Anne E. Carlisle, and Dohoon Kim
Methods for accurate and reproducible studies of pharmacological effects of selenium in cancer / Arun Kumar Selvam, Tímea Szekerczés, Sofia Björnstedt, Ali Razaghi, and Mikael Björnstedt
Using selenocysteine-specific reporters to screen for efficient tRNASec variants / Christina Z. Chung, Dieter Söll, and Natalie Krahn
Expressing recombinant selenoproteins using redefinition of a single UAG codon in an RF1-depleted E. coli host strain / Qing Cheng and Elias S.J. Arnér
Selenocysteine substitutions in thiyl radical enzymes / Juan Carlos Cáceres, Clara A. Bailey, Kenichi Yokoyama, and Brandon L. Greene
Expression of selenoproteins via genetic code expansion in mammalian cells / Jennifer C. Peeler and Eranthie Weerapana
Applying selenocysteine-mediated expressed protein ligation to prepare the membrane enzyme selenoprotein S / Rujin Cheng, Jun Liu, Vidyadhar Daithankar, and Sharon Rozovsky
Chemoproteomic interrogation of selenocysteine by low-pH isoTOP-ABPP / Daniel W. Bak and Eranthie Weerapana
SecMS analysis of selenoproteins with selenocysteine insertion sequence and beyond / Chenfang Si, Ye Cao, and Yaoyang Zhang
An accelerated and optimized algorithm of selenium-encoded isotopic signature targeted profiling for global selenoproteome analysis / Guogeng Jia, Jinjun Gao, Fan Yang, Tianyu Feng, and Chu Wang
Assay of selenol species in biological samples by the fluorescent probe Sel-green / Baoxin Zhang and Jianguo Fang
Identification of selenoprotein O substrates using a biotinylated ATP analog / Meghomukta Mukherjee and Anju Sreelatha
Application of alpha-methyl selenocysteine as a tool for the study of selenoproteins / Emma J. Ste. Marie and Robert J. Hondal
Modeling of selenocysteine-derived reactive intermediates utilizing a nano-sized molecular cavity as a protective cradle / Ryosuke Masuda and Kei Goto
Diselenide-selenoester ligation in the chemical synthesis of proteins / Max J. Bedding, Sameer S. Kulkarni, and Richard J. Payne.

Summary: This book is an open access under a CC BY license. The subject of this book relates to protein ligands with particular structural and complexation properties. They are composed of self-assembled molecules, capable of penetrating as a unit into proteins outside the binding site. The ribbon-like supramolecular system only permits the penetration of self-assembled molecules into the protein-body and formation of stable complexes. Supramolecular Congo red and similar compounds fit these requirements. Destabilized protein fragments enable the penetration of such ligands, with susceptibility to supramolecular ligand binding often associated with protein function. As a result, complexation modifies their functional effects. The activity of enzymes is inhibited by arresting them in the complexed state, but "naturally irreversible" complexation as in the case of immune complexation, is enhanced instead. This property offers many attractive possibilities of using supramolecular ligands as described in this book.

Contents:
Supramolecular systems as protein ligands
Supramolecular Congo Red as Specific Ligand of Antibodies Engaged in Immune Complex
Protein Conditioning for Binding Congo Red and Other Supramolecular Ligands
Metal Ions Introduced to Proteins by Supramolecular Ligands
Possible Mechanism of Amyloidogenesis of V Domains
Supramolecular Structures as Carrier Systems Enabling the Use of Metal Ions in Antibacterial Therapy
Congo Red Interactions with Single-Walled Carbon Nanotubes.

Summary: "An essential examination resource for anyone sitting their primary or maintenance of certification examinations in dermatology, pathology or dermatopathology, Self-Assessment in Dermatopathology uses histopathology as a catalyst for constructive and critical thinking and to trigger relevant clinical, genetic and syndromic associations. Concise explanations at the end of each chapter give short answers to each question and expand on each answer choice. Each chapter consists of an increasingly difficult selection of questions, allowing the reader to develop and self-test their knowledge. Tables relevant to the section covered have also been incorporated in the answer section. Using this practical approach, the reader will become familiar with the pathologic basis of clinically relevant dermatoses and cutaneous tumors. The question and answer format make this book the first resource of its kind. Thinking about information in a new way is the foundation of this book, making it an invaluable addition for any trainee"--Provided by publisher.

Contents:
Machine generated contents note:
1. General;
2. Genodermatoses and epidermal disorders;
3. Pigmentary disorders;
4. Tissue reaction patterns;
5. Disorders involving the dermis and, or subcutis;
6. Depositional diseases and cutaneous manifestations of systemic disease and depositional diseases;
7. Infections;
8. Tumors.

Summary: This practical study guide illustrates a variety of different scenarios of rheumatic disease in succinct question and answer format. It contains 120 complex cases with potentially unusual diagnoses designed to stimulate thought and further reading in this rapidly evolving specialty. The questions demonstrate both common and uncommon rheumatologic conditions that may be encountered on ward rounds or in clinic by using radiographs, pictures, and skin findings. Each case is based on a real-life diagnostic situation encountered by the author from his two decades of experience working in a busy consultative practice.Self Assessment in Rheumatology: An Essential Q & A Study Guide, Second Edition is an essential resource for students, postgraduate fellows, internists, and practicing physicians eager to learn more about rheumatology, test their fund of knowledge, or prepare for board examinations.

Contents:
Chapter 1. Assessment Questions 1-10
Chapter 2. Assessment Questions 11-20
Chapter 3. Assessment Questions 21-30
Chapter 4. Assessment Questions 31-40
Chapter 5. Assessment Questions 41-50
Chapter 6. Assessment Questions 51-60
Chapter 7. Assessment Questions 61-70.-Chapter 8. Assessment Questions 71-80
Chapter 9. Assessment Questions 81-90
Chapter 10. Assessment Questions 91-100
Chapter 11. Assessment Questions 101-110
Chapter 12. Assessment Questions 111-120.

Summary: "This comprehensive book describes the design, synthesis, mechanisms, characterization, fundamental properties, functions and development of self-healing smart materials and their composites with their allied applications. It covers cementitious concrete composites, bleeding composites, elastomers, tires, membranes, and composites in energy storage, coatings, shape-memory, aerospace and robotic applications. The 21 chapters are written by researchers from a variety of disciplines and backgrounds."-- Provided by publisher.

Contents:
Self-Healing Polymer Coatings / Facundo I Altuna, Cristina E Hoppe
Smart Phenolics for Self-Healing and Shape Memory Applications / Baris Kiskan, Yusuf Yagci
Self-Healable Elastomers / Mariajose Cova Sanchez, Daniela Belon Garcia, Mariano Martin Escobar, Marcela Mansilla
Self-Healable Tires / Norazlianie Sazali, Mohamad Azuwa Mohamed, Zul Adlan Mohd Hir
Self-Healing Bacterial Cementitious Composites / R Preetham, R Hari Krishna, MN Chandraprabha, R Sivaramakrishna
Self-Healable Solar Cells: Recent Insights and Challenges / Seyyed Alireza Hashemi, Seyyed Mojtaba Mousavi, Sonia Bahrani, Seeram Ramakrishna, Chin Wei Lai, Wei-Hung Chiang
Self-Healable Core-Shell Nanofibers / Sonia Bahrani, Seyyed Mojtaba Mousavi, Seyyed Alireza Hashemi, Chin Wei Lai, Wei-Hung Chiang
Intrinsic Self-Healing Materials / Angelita Cristiane Saul, Joao Henrique Zimnoch dos Santos
Self-Healable Catalysis / Bilge Cokuner Filiz
Self-Healing Materials in Corrosion Protection / Eiman Alibakhshi, Bahram Ramezanzadeh, Mohammad Mahdavian
Self-Healable Conductive Materials / M Ramesh, L Rajeshkumar, D Balaji, V Bhuvaneswari, S Sivalingam
Self-Healable Artificial Skin / Beg Younus Raza, Nishad Gokul Ram, Priyanka Singh
Self-Healing Smart Composites / Sithara Gopinath, Suresh Mathew, P Radhakrishnan Nair
Stimuli-Responsive Self-Healable Materials / G Jerald Maria Antony, S Raja, ST Aruna
Mechanically-Induced Self-Healable Materials / M Ramesh, L Rajeshkumar, R Saravanakumar
Self-Healing Materials in Robotics / Sunny Kumar
Self-Healing Materials in Aerospace Applications / M Harikrishna Kumar, C Moganapriya, A Moha Kumar, R Rajasekar, V K Gobinath
Bio-Inspired Self-Healable Materials / Archita Sharma, Shailendra Kumar Arya
Self-Healable Batteries / Seyyed Mojtaba Mousavi, Maryam Zarei, Seyyed Alireza Hashemi, Wei-Hung Chiang, Chin Wei Lai, Sonia Bahrani
Self-Healing in Bleeding Composites / Lutfur Rahman, Ata Ullah, Muhammad Bilal Yazdani, Muhammad Irfan, Waheed S Khan, Asma Rehman
Self-Healing Polymers / Muhammad Akram, Charles Oluwaseun Adetunji, Mohd Imran Ahamed, Adrish Sohail, Iram Ghaffar, Olugbenga Samuel Michael, Hina Anwar, Musa Abidemi Muhibi, Juliana Bunmi Adetunji, Umme Laila, Mathew Olaniyan.

Summary: "An injury to the brain can affect virtually any aspect of functioning and, at the deepest level, can alter sense of self or the essential qualities that define who we are. In recent years, there has been a growing body of research investigating changes to self in the context of brain injury. Developments in the cognitive and social neurosciences, psychotherapy and neurorehabilitation have together provided a rich perspective on self and identity reformation after brain injury. This book draws upon these theoretical perspectives and research findings to provide a comprehensive account of the impact of brain injury on self-identity. The second half of this book provides an in-depth review of clinical strategies for assessing changes in self-identity after brain injury, and of rehabilitation approaches for supporting individuals to maintain or re-establish a positive post-injury identity. The book emphasizes a shift in clinical orientation, from a traditional focus on alleviating impairments, to a focus on working collaboratively with people to support them to re-engage in valued activities and find meaning in their lives after brain injury. Self-Identity after Brain Injury is the first book dedicated to self-identity issues after brain injury which integrates theory and research, and also assessment and intervention strategies. It will be a key resource to support clinicians and researchers working in brain injury rehabilitation, and will be of great interest to researchers and students in clinical psychology, neuropsychology, and allied health disciplines"-- Provided by publisher.

Contents:
1. Overview of self-identity after brain injury
2. What is the self? Historical and contemporary accounts
3. Introduction to brain injury and consequences during childhood and adolescence
4. Psychological adjustment and self-identity changes after brain injury
5. Approaches for assessing changes to self after brain injury
6. Individual psychotherapy and neurorehabilitation approaches
7. Group and community-based interventions
8. Family and paediatric Interventions
9. Summary and future directions.

Contents:
v. 1, Body structure and function, nutrition and food management, basic pharmacology and drug therapy ; v. 2, Roles and responsibilities in nursing health ; v. 3, Medical and surgical nursing, mental illness ; v. 4, Mother and newborn, the well and sick child, communicable diseases.

Summary: Self-management is a term that was used as early as the 1960s when it was applied during the rehabilitation of chronically ill children. Subsequently, self-management was applied as formalized programs for a variety of populations and health issues. In reflecting on self-management, it is important to note that it would be difficult for individuals not to be aware of their specific health behaviors, which could include unhealthy behaviors. As self-management has evolved, essential skills identified include behavioral modeling, decision making, planning, social persuasion, locating, accessing and utilizing resources, assisting individuals to form partnerships with their health care providers and taking action. These are key skills that would benefit health professional educators, clinicians and patients. This book, consisting of three parts, provides insights into the aspects of self-management as it relates to its definition and application. It highlights how self-management can be applied to various long-term health conditions, for different populations or target groups and in different contexts. The text provides an overview of self-management and the rationale for its applications by illustrating its use in specific clinical conditions and in different sub-populations and target groups. Academics can use the book as a textbook when teaching postgraduate and undergraduate students about self-management as a technique to facilitate community reintegration for individuals living with long-term conditions. It can also be used by clinicians to enhance their management of individuals with long-term conditions. Furthermore, researchers can use the text to expand and support their research in this area.

Contents:
Part I: Understanding self-management
1. Overview of self-management
2. The case for self-management
Part II: The application of self-management in various conditions
3. Self-management and spinal cord injuries
4. Self-management in diabetes
5. Self-management and stroke
6. Self-management and low back pain
Part III: Using self-management across the lifespan and across settings
7. Self-management in youth
8. Self-management in chronic illness in the elderly
9. Community health workers as key contributors to self-management programs
10. Self-management in the workplace
11. Self-management in nutrition and exercise.

Summary: This book focuses on young people (12-25 years old) growing up with a chronic somatic condition and/or physical disability, facing different challenges during their transition to adulthood and to adult healthcare services. Becoming an adult often proves extra challenging for them, because the adaptive tasks related to living with a chronic condition can clash with developmental milestones. Finding a good balance and integrating these tasks in daily life is also referred to as self-management. This book addresses self-management and empowerment of young people with chronic conditions as well as the Positive Youth Development concept. It elaborates on theories and approaches and offers a complete overview of self-management interventions for young people with chronic conditions, emphasizing on the tasks of medical, emotion and role management. It also elaborates on the roles and tasks of professionals, as well as the patient-provider relationship; the shifting roles between young people and their parents and the role of peer support. This book is unique in its broad view on self-management, i.e. it goes beyond medical management and focuses on young people achieving their maximum potential and a good quality of life. Furthermore, the book employs a positive youth development approach, focusing on empowerment and growth rather than problems or issues. It offers an overview of the state-of-the-art and evidence concerning self-management support for young people with various chronic conditions. As such it is of benefit for all healthcare professionals working in care for young people, but also for researchers interested in this topic.

Contents:
Self-Management of Young People with Chronic Conditions: An Overview and Introduction / AnneLoes van Staa, Sander R. Hilberink, and Jane N. T. Sattoe
Positive Youth Development Approach to Support Life Skills of Young People with Chronic Conditions / Alison R. S. Manning, Jodie Neukirch Elliott, Samuel M. Brotkin, Gary Maslow, and McLean D. Pollock
The Development of Self-Management in Young People with Chronic Conditions: A Transitional Process / Jane N. T. Sattoe and AnneLoes van Staa
Exploring Components and Effects of Self-Management Interventions for Young People with Chronic Conditions / Marjolijn I. Bal, Jane N. T. Sattoe, Pepijn D. D. M. Roelofs, and AnneLoes van Staa
Self-Management Support for Young People with Chronic Conditions: Roles and Views of Professionals / Janet E. McDonagh
Transition to Adulthood: Shifting Roles Between Young People with Chronic Conditions and Their Parents / Karen L. Shaw, Gemma Heath, and Albert Farre
Peer Support for Young People with Chronic Conditions / Susan Kirk and Linda J. Milnes
Skills for Growing Up and Ready Steady Go: Practical Tools to Promote Life Skills in Youth with Chronic Conditions / Jane N. T. Sattoe, AnneLoes van Staa, Marij E. Roebroeck, and Sander R. Hilberink.

Contents:
Introduction / Juan M. Cabases and Rosalind Rabin
Data and Methods / Bas Janssen, Agota Szende, and Juan Manuel Ramos-Goni
Population Norms for the EQ-5D / Bas Janssen and Agota Szende
Cross-Country Analysis of EQ-5D Data / Agota Szende and Bas Janssen
Socio-demographic Indicators based on EQ-5D / Agota Szende and Bas Janssen
Annex 1: EQ-5D population norms - National surveys
Annex 2: EQ-5D population norms - Regional surveys
References
Index.

Summary: "Depression is one of the most common forms of psychological distress and can have devastating consequences for individuals and their loved ones. Decades of research have shown that there are many possible causes of depression, and one of those causes involves problems with self-regulation. Self-regulation involves setting and pursuing important personal goals - put simply, the process of trying to be the kind of person you want to be. Self-System Therapy for Depression: Therapist Guide provides a thorough description of Self-System Therapy (SST)-a motivational approach to treating depression that helps decrease feelings of disappointment and failure and increase feelings of pride and accomplishment, by improving the process of self-regulation. Clinical studies have shown that SST is effective in reducing depression and anxiety. The treatment program is structured within a 16-session plan, and strategies and techniques for each phase of treatment are presented in detail, along with case vignettes and examples. The core strategies of SST focus on identifying appropriate and reasonable personal goals and standards (including coping with perfectionistic standards), evaluating and improving the effectiveness of goal pursuit strategies, and adjusting goals in order to improve opportunities for positive emotions. The accompanying Client Workbook explains the basics of self-regulation in simple terms and provides worksheets to help illustrate and implement these strategies."-- Provided by publisher.

Contents:
Part I: Background for the Therapist
Chapter 1: Introduction to This Guide
Chapter 2: Theoretical Overview
Chapter 3: Is SST Right for My Client?
Chapter 4: Overview of SST Strategies
Part II: Therapy Phases and Strategies
Chapter 5: Orientation Phase (Sessions 1
4)
Chapter 6: Exploration Phase (Sessions 5
8)
Chapter 7: Adaptation Phase (Sessions 9
15)
Chapter 8: Termination and Relapse Prevention.

Summary: "Semen Analysis Benchtop Reference Guide is an illustrated guide to sperm morphology. The content includes specimen collection and macroscopic assessment, sperm count, and morphology assessment and classification systems. Also included are 50 images representing normal morphology, head defects, neck/midpiece defects, tail defects, and residual cytoplasm defects, as well as images of nonsperm cells, Pap-stained sperm, and equipment."-- Provided by publisher.

Summary: "The 2nd edition of this book was edited by David King and published in 2004. Since then there have been major advances in psychopharmacology in terms of new medications coming to the market, increased understanding of the mechanisms of drug action and new data on the efficacy, tolerability, safety and clinical effectiveness of a range of medications. Partly as a result, clinical guidelines for many psychiatric disorders have altered. As such, a new edition of this textbook was essential and we were delighted when the College approached us to edit the 3rd edition. This was a major endeavor that was only possible with the commitment and expertise of the authors"-- Provided by publisher.

Summary: A concise and up-to-date text on the mental health of older people, this second edition is fully updated to reflect changes in technology, competency-based training, guidelines, law and treatments. Each chapter sits alone as an informative, readable and helpful resource for a range of health care professionals. Together the chapters form an essential text that contributes to the rising standards in old age psychiatry. With practical guidelines on clinical management, this edition also includes new sections on topics such as palliative care and migrant health, all written by a global authorship, considering international perspectives. Targeted at qualified and trainee consultant psychiatrists, this text is also useful to other doctors, medical students and healthcare professionals who work with older people.

Summary: This monograph is about new perspectives in animal studies methodology, by using concepts and tools from the field of semiotics. It proposes a reflexion on current challenges and issues in the ethology field, and introduces different semiotics - biosemiotics, zoosemiotics - as potential methodological solutions. The chapters cover many aspects of ethology where semiotics can be a helpful hand: studies of language, culture, cognition or emotions, issues about complex, endangered or variable species. It explains why these points are difficult to study for actual ethology, why they still matter for researchers, biodiversity actors or wildlife programs, and how an interdisciplinary study with a semiotic point of view can help understand them. This book will appeal to a wide readership, from researchers and academics in living sciences as well as in linguistics fields, to other professionals - veterinarian, wildlife managers, zookeepers, and many others - who feel the need to better understand some aspects of animals they are working with. Students with animal focus should read this book as an introduction to interdisciplinary methodology, and a proposition to work differently with animals.

Contents:
Intro; Acknowledgements; Contents; About the Author; List of Figures; List of Tables;
Chapter 1: Introduction and Purpose; 1.1 Creation Process; 1.1.1 About the Subject; 1.1.2 About the Corpus; 1.1.3 About the Academic and Social Impact; 1.2 Why Use Semiotics in Animal Studies; 1.2.1 History of Semiotics; 1.2.2 History of Animal Studies; 1.3 Questions About Methodology; 1.3.1 Studying a Subject from Different Academic Fields; 1.3.2 Including New Corpus Categories; 1.3.3 Hypothesis, Biases and Ideologies; References;
Chapter 2: Debates and Controversies; 2.1 Existing Controversies 2.1.1 Language2.1.2 Consciousness; 2.1.3 Emotions; 2.2 The Perspective of Humanities; 2.2.1 What Is an Animal?; 2.2.2 What Are Language Sciences For?; 2.2.3 The Specific French Academic Tradition; 2.3 Author Position; 2.3.1 The "Lesser Evil" Position; 2.3.2 About the Particular Case of Definitions; References;
Chapter 3: Necessary and Problematic Definitions; 3.1 Necessary Definitions; 3.1.1 Emotion; 3.1.2 Consciousness; 3.1.3 Memory; 3.2 Problematic Definitions; 3.2.1 Language; 3.2.2 Emotions; 3.2.3 Intelligence; 3.2.4 Culture; References;
Chapter 4: Semiotic Tools and Concepts 4.1 How to Pick Semiotic Tools4.1.1 Relevance; 4.1.2 Peirce's Tools; 4.1.3 Intensity, Frequency, Context; 4.2 Semiotic Concepts; 4.2.1 Intentional, Conscious, Unconscious; 4.2.2 Jakobson's Functions of Language; 4.2.3 Eco's Semiotic Theory; 4.2.4 About the Case of Anthropomorphism; References;
Chapter 5: Intertheoricity: How to Build Bigger Models; 5.1 What Is Intertheoricity; 5.1.1 Academic Position About Interdisciplinarity; 5.1.2 Difficulties and Flaws of Interdisciplinarity; 5.1.3 Guillaume's Theory; 5.2 How Intertheoricity Allows for Bigger Models; 5.2.1 A Shared Methodology 5.2.2 Definitions: Harmonisation and Creation5.2.3 How Concepts "Communicate" with Each Other; 5.3 Why We Need Bigger Models; 5.3.1 More Complex Subjects; 5.3.2 Over-Specialised Researchers; 5.3.3 More Impact, Less Time; References;
Chapter 6: Strengths and Flaws of Ethological and Biological Methodology; 6.1 Strengths to Work with; 6.1.1 Ancient and Strong Field; 6.1.2 Evolutive Methodology; 6.1.3 Observation-Based Science; 6.2 Flaws to Counter; 6.2.1 Leaving or Not Leaving the Laboratory; 6.2.2 Observation Is Disruption; 6.2.3 How Ideology Can Be Rooted in Science; References
Chapter 7: Animal Studies, Animal Ethics7.1 Issues in Animal Studies; 7.1.1 Working with Living Beings; 7.1.2 Difficulty to Understand Stranger Minds; 7.1.3 Situation of Emergency; 7.2 Ethical Issues; 7.2.1 About Endangered Species; 7.2.2 About Complex Species; 7.2.3 About Pain in Animals; 7.3 Solutions of Semiotic Methodology; 7.3.1 On General Issues; 7.3.2 On Ethical Issues; References;
Chapter 8: Building Zoosemiotics; 8.1 Between Semiotics and Animal Studies; 8.1.1 Semiotics and Biosemiotics; 8.1.2 Biosemiotics and Zoosemiotics; 8.2 Progress Wanted, and Progress Needed; 8.2.1 Where We Are

Summary: This book describes a fully integrated approach to the management of elderly patients who are at risk of or suffer trauma, drawing on up-to-date knowledge from multiple specialties in recognition of the fact that the number and severity of comorbidities in this population requires expertise in many fields. Readers will find comprehensive and detailed coverage of the prevention of complications related to aging, geriatric care concepts, specific treatments in acute care, including fracture stabilization and diagnostic procedures, and the surgical management of different types of fracture and soft tissue trauma. Intensive care management of the geriatric patient is also extensively addressed. Information is provided on diverse aspects of the physiology of ageing, and the coverage is completed by discussion of fracture care service models and specific models of rehabilitation and aftercare designed to prevent further falls and adverse late outcomes. The authors are a group of renowned experts from each of the relevant fields, and the book will be a valuable asset for surgeons, intensivists, geriatricians, gerontologists, and rehabilitation specialists.

Contents:
Introduction Physiology of ageing
Prevention of complications related to ageing
Geriatric Care concepts in acute care
Fracture care service models
Specific treatments in acute care
Surgical management of major fractures
Intensive Care Management of the geriatric patient
Rehabilitation and outcomes.

Summary: This book offers comprehensive information on the new and rapidly evolving science of identifying and targeting senescent cells, and on the exciting prospect of new diagnostic and therapeutic opportunities for stopping, and even reversing, the progression of disease and the deterioration of the human body due to ageing. According to recent United Nations data, by 2050 one in six people worldwide will be older than age 65, with peaks rising to one in four people in Europe and North America. Remarkably, the number of persons aged 80 years or older is expected to triple, from 143 million in 2019 to 426 million in 2050. First documented in the 1960s, the concept of cellular senescence as an underlying cause of ageing has been established in the course of the last decade. Using genetically engineered mouse models, researchers have demonstrated that the selective elimination of senescent cells can block and even reverse a number of age-related dysfunctions and pathologies, promoting both better health and longer life in the elderly. These include cardiovascular diseases; neurological disorders; type 1 and type 2 diabetes; inflammatory diseases; fibrosis; geriatric syndromes; chronic diseases resulting in organ dysfunction; the integrity of the musculoskeletal system; and cancer. Some senolytic agents have already progressed into trials. These include UBX0101 for the treatment of osteoarthritis (now in phase II), a cocktail of dasatinib and quercetin for the management of idiopathic pulmonary fibrosis and chronic kidney disease, and ABT-263 in combination with senescence-inducing chemotherapies for the treatment of advanced solid tumours. In addition, the book discusses pathways to early phase clinical trials and translational approaches in medicine and ageing, highlighting new opportunities as well as current limitations, challenges and alternatives. Given its scope, it will benefit a broad audience of advanced educators, researchers, graduate students and practitioners.

Contents:
Part I: Origins and Development of Senotherapies
Chapter 1. Senolytic drug development
Chapter 2. Discovery of Senolytics and the pathway to early phase clinical trials
Part II: The Impact of Senotherapies: from Regeneration to Aging
Chapter 3. Interconnection between cellular senescence, regeneration and ageing in salamanders
Chapter 4. Senolytics target senescent cells and improve aging and age-related diseases
Chapter 5. Senotherapy of cancer
Part III: Understanding and Targeting the Senescent Surfaceome
Chapter 6. Targeted senolytic strategies based on the senescent surfaceome
Chapter 7. Senolysis and senostasis through the plasma membrane
Part IV: Novel Senescence-Associated Markers and Targets
Chapter 8. In situ detection of miRNAs in senescent cells in archival material
Chapter 9. Novel probes and carriers to target senescent cells
Chapter 10. Potential applications of aptamers for targeting senescent cells
Chapter 11. Mitochondria: potential targets for interventions to counteract senescence.

Summary: This book covers sensation in all major components of the pelvic region. The small pelvis is containing many different structures and viscera, and sensations elicited there are important for regulating a normal daily life and for warning that something is going wrong. The sensory system is driving in many aspects the motor activity, and precedes and guides the efferent functions. It is surprising that in the last 60 years the ratio between research and publications about sensory versus motor has gradually become less. There has been undoubtedly a rise in the number of publications written on pelvic sensation but in the same time the number of manuscripts on motor function have increased more. It is the hope that this compilation of most data available on sensation will be of interest for the reader, will incite to perform more research so that an important part of pelvic functional diagnosis and treatment modalities will use the whole of the mechanisms available. The book is intended for all interested in pelvic functions and the interactions between the different structures, specialists in urology, gastroenterology, sexuality, pain, pelvic floor function and dysfunction, paediatricians and geriatricians, neurologists, students and those in training . The reader will find interesting and challenging information, and suggestions for further research.

Contents:
Sensation
Bladder
Urehra
Pain
Pelvic floor
Diagnosis
Technical tests
Psychology
Kidneys
Bowel
Neuropathy
Bladder training.

Summary: "The Senses: A Comprehensive Reference, Second Edition, is a comprehensive reference work covering the range of topics that constitute current knowledge of the neural mechanisms underlying the different senses. This important work provides the most up-to-date, cutting-edge, comprehensive reference combining volumes on all major sensory modalities in one set. Offering 264 chapters from a distinguished team of international experts, The Senses lays out current knowledge on the anatomy, physiology, and molecular biology of sensory organs, in a collection of comprehensive chapters spanning 4 volumes. Topics covered include the perception, psychophysics, and higher order processing of sensory information, as well as disorders and new diagnostic and treatment methods. Written for a wide audience, this reference work provides students, scholars, medical doctors, as well as anyone interested in neuroscience, a comprehensive overview of the knowledge accumulated on the function of sense organs, sensory systems, and how the brain processes sensory input. As with the first edition, contributions from leading scholars from around the world will ensure The Senses offers a truly international portrait of sensory physiology. The set is the definitive reference on sensory neuroscience and provides the ultimate entry point into the review and original literature in Sensory Neuroscience enabling students and scientists to delve into the subject and deepen their knowledge."--publisher's web page, viewed September 10, 2020.