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Books

  • Digital
    John T. Gorczyca, editors.
    Summary: Utilizing detailed case presentations from experts in the field, this book presents common clinical scenarios involving patients who have sustained displaced femoral neck fractures, discussing the injury mechanism, early treatment, potential treatment options, risks and complications involved. The style of presentation, the ease of readability, the use of appropriate and relevant cases to highlight the learning points, and the discussion of the decision-making process are all unique features of the book's approach. Using this tailored process, the each topic is reviewed and the rationale for what appears to be the optimal treatment - hemiarthroplasty or total hip replacement, for example -- is provided to the reader, emphasizing that the ultimate decision requires the combination of science and judgment, both of which are continually evolving. Additional chapters present ongoing controversies in the management of these challenging fractures, as well as complications such as aseptic necrosis, symptomatic hardware and nonunions. Portable and concise, orthopedic and trauma surgeons, residents and fellows alike will find Displaced Femoral Neck Fractures a practical and user-friendly resource.

    Contents:
    Displaced Femoral Neck Fractures in Young Healthy Patients: The Evaluation
    Displaced Femoral Neck Fractures in Young Healthy Patients: The Science
    Displaced Femoral Neck Fractures in Young Healthy Patients: The Technique
    Treatment of Displaced Femoral Neck Fractures with Hemiarthroplasty
    Treatment of Displaced Femoral Neck Fractures with Total Hip Arthroplasty
    How to Sort Out the Controversies in Displaced Femoral Neck Fractures
    Complications with Displaced Femoral Neck Fractures: Aseptic Necrosis
    Complications with Displaced Femoral Neck Fractures: Symptomatic Hardware
    Complications with Displaced Femoral Neck Fractures: Nonunion.
    Digital Access Springer 2022
  • Digital/Print
    Hans Steiner, Whitney Daniels, Christina Stadler, Michael Kelly.
    Summary: Disruptive behavior is extremely common. This book discusses state of the art studies of taxonomy, epidemiology, etiology, and treatment, along with forensic implications. Each chapter concludes with a series of clinical cases. Resources are provided for clinicians, researchers, teacher, primary care physicians, criminologists, forensic experts and interested lay people.

    Contents:
    Introduction to disruptive behavior disorders
    Taxonomy, classification, & diagnosis of disruptive behavior disorders
    Epidemiology of disruptive behavior disorders
    Etiology of disruptive behavior disorders
    Comprehensive and integrated treatment
    Disruptive behavior : forensic implications.
    Digital Access Oxford 2017
    Print Access Request
    Location
    Version
    Call Number
    Items
    Books: General Collection (Downstairs)
    RC454 .S75 2017
    1
  • Digital
    Jody Ranck, editor.
    Contents:
    Chapter 1: Introduction to Digital Health
    Chapter 2: Overview of the Digital Health Ecosystem
    Chapter 3: Diabetes and the Telcare Solution (Jonathan Javitt, Telcare)
    Chapter 4: Cooperation in Aging Services Technologies
    Chapter 5: The Quantified Self, Wearables, and the Tracking Revolution
    Chapter 6: Beyond Silos to Data Analytics for Population Health: Case Study of HealthBank and Citizen Coops for Health Data Transactions
    Chapter 7: Healthcare Lessons From the Telecommunications Sector (Sven Schuchardt, Detecon)
    Chapter 8: Smart Healthy Cities: Public-Private Partnerships, a Case From Telefonica in Brazil [Jody Ranck, Katia Galvane (Telefonica), Washington Tavares (ISPM)]
    Chapter 9: Smart Digital Health Policies (Ticia Gerber, HL7)
    Chapter 10: Cooperation for Building Secure Standards for Health Data (Cem Senturk, Detecon)
    Chapter 11: Peer to Peer Platforms for Physicians in Underserved Areas: A Human Rights Approach to Social Media in Medicine: The Case of Tabeeb (Osama Alshaykh).
    Digital Access Springer 2016
  • Digital
    Rade B. Vukmir.
    Summary: This book explores a rapidly growing area of discussion in the health care industry, disruptive behavior in medical providers. The presence of disruptive behavior adversely impacts the providers of all disciplines: paraprofessional personnel, nurses, physicians and administrators. But more importantly, there may be a greater detrimental effect on quality and patient safety. This has led to mandated regulatory requirements that assist healthcare institutions in developing programs to address the problem. The book presents an evidence-based analysis of the disruptive provider behavior that defines the incidence, demographics, and profile of the behavior; discusses the specialties and work locations predisposed, as well as the interface with residents and nurses. The importance of patient safety, economic, and legal issues are addressed by a comprehensive, management strategy to effect positive, sustainable culture change in healthcare.

    Contents:
    Introduction
    Scope of the Problem
    Organizational Approach
    Maturation of the Analysis
    Profile of the Behavior
    Location at Risk
    Specialty at Risk
    Physicians in Training
    Etiology
    Nursing Interface
    Patient Safety
    Policy and Guidelines
    Economic Issues
    Legal Interface
    Regulatory Interventions
    Strategies for Improvement
    Educational Process
    Management's Responsibility
    Conclusion
    Appendix: Situational Analysis and Approach: Case Scenarios.
    Digital Access Springer 2016
  • Digital
    Xue Han, Yuanyuan Wu, Jie Zheng.
    Summary: The book addresses the prevalent digital transformation and focuses on its significant disruption in healthcare. In light of the distinctive characteristics and evolution of the Chinese healthcare industry, private multi-sided platform (MSP) companies emerge to offer novel values and explore the industry value chain. Drawing on the management and economics literature of MSPs, this book examines the selected Chinese MSPs and compares them with the counterpart MSPs in the U.S. This analysis highlights how the unfolding healthcare disruption is valuable for both scholars and practitioners to understand the trends and to take effective actions. "Disruptive Innovation through Digital Transformation: Multi-Sided Platforms of E-Health in China" provides readers in the developing and developed countries with insights on how to approach the current multi-sided platform and to resolve the current problems to better serve customers and patients in the healthcare market.

    Contents:
    Intro
    Acknowledgements
    About This Book
    Contents
    List of Figures
    List of Tables
    1 Demands for Healthcare Industry Changes Provide the Soil for Digital Transformation
    1.1 Problems in the Healthcare Industry and the Impact of Digital Transformation
    1.2 The Transformation Scenario in E-Health
    1.3 Distinctive Chinese Healthcare Evolution Surpassing Typical Digital Transformation Developments
    1.4 Overview of the Book
    1.4.1 Starting Point
    1.4.2 Theoretical Approach
    1.4.3 Research Methodologies
    1.4.4 Research Route
    1.5 Structure of the Book 2 Digital Transformation, Multi-sided Platforms, and Analytical Framework
    2.1 Transformation by Business Model Innovation
    2.1.1 Disruption in Initially Serving the New Market: The Ignored Low-End Market or Non-existing Market
    2.1.2 Disruption in Serving Complementary Markets
    2.1.3 Disruption in Integrating and Serving the Whole Value Chain
    2.2 Multi-sided Platforms (MSPs)
    2.2.1 Characteristics of MSPs
    2.2.2 The Importance of MSP Governance
    2.2.3 Two-Stage Management of MSPs
    2.2.4 Solving Chicken-and-Egg Problems
    2.3 Analysis Model Suggested 3 Distinctive Characteristics of the Chinese Healthcare Industry
    3.1 Ongoing Reforms in the Chinese Healthcare System
    3.2 The Current E-Health Ecosystem in China
    3.2.1 Key Players in the Chinese E-Health Ecosystem
    3.2.2 Dominant Players in the Chinese E-Health Ecosystem
    3.2.3 Interactions Between Players in the E-Health Ecosystem
    3.3 Distinctive Characteristics of the Chinese Healthcare System
    3.3.1 The Huge Medical Demands and Significant Imbalances
    3.3.2 The Improving Medical Insurance System and Higher Percentage of Out-of-Pocket Payment 3.3.3 High Concentration of Visits in Comprehensive Hospitals
    3.3.4 Ongoing Reform on the Multi-site License of Certified Physicians
    3.3.5 Pressures of Career Advancement for Physicians
    3.4 Great Opportunities for E-Health and MSP to Disrupt the Traditional Chinese Healthcare Market
    4 Emerging E-Health MSPs in China
    4.1 www.chunyuyisheng.com
    4.1.1 The Involved Sides
    4.1.2 Services and Advantages
    4.1.3 The Chicken-Egg Solution
    4.1.4 Cooperation-Competition with Other Practitioners
    4.2 www.dxy.cn
    4.2.1 The Involved Sides
    4.2.2 Services and Advantages 4.2.3 The Chicken-Egg Solution
    4.2.4 Cooperation-Competition with Other Practitioners
    4.3 www.xingren.com
    4.3.1 The Involved Sides
    4.3.2 Services and Advantages
    4.3.3 The Chicken-Egg Solution
    4.3.4 Cooperation-Competition with Other Practitioners
    4.4 www.guahao.com
    4.4.1 The Involved Sides
    4.4.2 Services and Advantages
    4.4.3 The Chicken-Egg Solution
    4.4.4 Cooperation-Competition with Other Practitioners
    4.5 www.manyoubang.com (Manyoubang)
    4.5.1 The Involved Sides
    4.5.2 Services and Advantages
    4.5.3 The Chicken-Egg Solution
    Digital Access Springer 2020
  • Digital
    edited by Ross C. Brownson, Graham A. Colditz, Enola K. Proctor.
    Contents:
    The promise and challenges of dissemination and implementation research / Graham A. Colditz and Karen M. Emmons
    Terminology for dissemination and implementation research / Borsika A. Rabin and Ross C. Brownson
    Historical roots of dissemination and implementation science / James W. Dearing, Kerk F. Kee, and Tai-Quan Peng
    Ethical issues in dissemination and implementation research / James M. Dubois and Beth Prusaczyk
    The conceptual basis for dissemination and implementation research: lessons from existing models and frameworks / Rachel G. Tabak, David A. Chambers, Mary Hook, and Ross C. Brownson
    The role of economic evaluation in dissemination and implementation research / Ramesh Raghavan
    Designing for dissemination in chronic disease prevention and management / Neville Owen, Ana Goode, Takemi Sugiyama, Mohammad Javad Koohsari, Genevieve Healy, Brianna Fjeldsoe, and Elizabeth Eakin
    The role of organizational processes in dissemination and implementation research
    Gregory A. Aarons, Joanna C. Moullin, and Mark G. Ehrhart
    Systems thinking and dissemination and implementation research / Barbara L. Riley, Cameron D. Willis, Bev Holmes, Diane T. Finegood, Allan Best, and Jessie-Lee D. McIsaac
    Systems science methods in dissemination and implementation research / Douglas A. Luke, Alexandra B. Morshed, Virginia R. McKay, and Todd B. Combs
    Participatory approaches for study design and analysis in dissemination and implementation research / Meredith Minkler, Alicia L. Salvatore, and Charlotte Chang
    Enhancing dissemination through marketing and distribution systems: a vision for public health / Joseph T. Steensma, Matthew W. Kreuter, Christopher M. Casey, and Jay M. Bernhardt
    Design and analysis in dissemination and implementation research / John Landsverk, C. Hendricks Brown, Justin D. Smith, Patricia Chamberlain, Geoffrey M. Curran, Lawrence Palinkas, Mitsunori Ogihara, Sara Czaja, Jeremy D. Goldhaber-Fiebert, Wouter Vermeer, Lisa Saldana, Jennifer A. Rolls Reutz, and Sarah McCue Horwitz
    Measurement issues in dissemination and implementation research / Cara C. Lewis, Enola K. Proctor, and Ross C. Brownson
    Implementation strategies / Joann E. Kirchner, Thomas J. Waltz, Byron J. Powell, Jeffrey L. Smith, and Enola K. Proctor
    Fidelity and its relationship to implementation effectiveness, adaptation, and dissemination / Jennifer D. Allen, Rachel C. Shelton, Karen M. Emmons, and Laura A. Linnan
    Adaptation in dissemination and implementation science / Ana A. Baumann, Leopoldo J. Cabassa, and Shannon Wiltsey Stirman
    Furthering dissemination and implementation research: the need for more attention to external validity / Lawrence W. Green and Mona Nasser
    Evaluation approaches for dissemination and implementation research / Bridget Gaglio and Russell E. Glasgow
    Mixed methods evaluation in dissemination and implementation science / Lawrence A. Palinkas and Brittany Rhoades Cooper
    Dissemination and implementation research in community and public health settings / Cynthia A. Vinson, Katherine A. Stamatakis, and Jon F. Kerner
    Dissemination and implementation in social service settings / J. Curtis McMillen and Danielle R. Adams
    Implementation science in health care / Alison B. Hamilton and Brian S. Mittman
    Health dissemination and implementation within schools / Rebekka M. Lee and Steven L. Gortmaker
    Dissemination and implementation research in worksites / Peggy A. Hannon and Jeffrey R. Harris
    Policy dissemination research / Jonathan Purtle, Elizabeth A. Dodson, and Ross C. Brownson
    Dissemination and implementation research among racial/ethnic minority and other vulnerable populations / Antronette (Toni) Yancey, Beth A. Glenn, Chandra L. Ford, and Lashawnta Bell-Lewis
    Dissemination and implementation research in a global context / Rebecca Lobb, Shoba Ramanadhan, and Laura Murray
    Future issues in dissemination and implementation research / Ross C. Brownson, Graham A. Colditz, and Enola K. Proctor.
    Digital Access Oxford 2018
  • Digital
    Michael C. Klein.
    Summary: "How often do you hear a doctor saying doctors need to be more accountable, Medicare needs more support and family medicine deserves more respect? Dissident Doctor bristles with refreshingly frank criticisms from inside the health sector, and its author is not just any doctor but a distinguished scientific researcher, veteran medical administrator, Professor Emeritus, recipient of the Order of Canada and lifelong gadfly. In Dissident Doctor, Michael C. Klein intersperses fascinating tales of individual cases with formative elements of his personal life. As the son of American left-wing activists, he grew up singing folk songs about justice and racial equality; as a young doctor his refusal to serve as a military physician during the Vietnam War prompted his immigration to Canada. His early experience working with midwives in Ethiopia-delivering babies using techniques for natural pain relief and without routine episiotomy-were formative, leading him to question many standard but unjustified procedures in Western maternity care. He made many unconventional decisions as a result of his focus on humane medicine, transitioning from a specialization in pediatrics and newborn care to become a family physician, and embracing midwifery before it was approved in Canada. Klein's determination in the face of great opposition, the strength of his convictions, and his humility and sense of humour drive this powerful story of a life and career dedicated to his patients and his principles."-- Provided by publisher.
  • Digital
    Jeffrey N. Lawton, editor and author.
    Contents:
    1. Teatment of metaphyseal distal radius fractures with a volar locking plate
    2. Volar plate/hook pin for volar lunate facet fragment
    3. Volar locking plate + dorsal-ulnar plate
    4. Volar locking plate and radial styloid plating
    5. Volar locking plate for intra-articular distal radius fracture
    6. Dorsal plate fixation for distal radius fractures
    7. Fragment-specific internal fixation of distal radius fractures
    8. Volar ulnar fixation
    9. Fractures of the radial column
    10. Distal radius fracture: Kapandji (intrafocal) pinning technique
    11. Bridge plating for distal radius fractures
    12. External fixation and percutaneous pinning for distal radius fractures
    13. Ulnar styloid fracture with distal radioulnar joint instability
    14. Distal radius fractures with ulnar head and neck fractures
    15. DRUJ dislocations/ Galeazzi fracture
    16. Distal radius fractures: a clinical casebook
    17. Loss of fixation in distal radius fractures
    18. Distal radius fracture complicated by carpal tunnel syndrome
    19. Complications of distal radus fracture: EPL rupture
    Index.
    Digital Access Springer 2016
  • Digital
    Leiv M. Hove, Tommy Lindau, Per Hølmer, editors.
    Summary: Distal radial fractures are still puzzling us 200 years after Colles' classic description. Despite the advent of various new imaging techniques, including 3D CT, the availability of diagnostic adjuncts such as arthroscopy, and treatment options that include more than 30 different volar locking plates, the rate of unsatisfactorytreatment resultsremains very high. Furthermore, while we are aware of more associated injuries, such as carpal ligament tears and injuries to the radioulnar ligament (TFCC), there is still intense debate on the relevance of these injuries. This textbook aims to provide the reader with a complete understanding of distal radius fractures, their inherent problems, and how to manage them successfully. It is written by widely published experts from a part of the globe where distal radius fractures are very common, especially during the winter months. Clear guidance is provided on diagnostic imaging, classification, and assessment of fracture instability. The complete spectrum of operative and nonoperative treatment options are then clearly explained with the aid of step-by-step illustrations. Extensive information is also provided on complications and their treatment. Both students and experienced practitioners will find this book to be an enlightening, practice-oriented reference on the management of these challenging fractures.

    Contents:
    Distal Radius Fractures: What Is the Problem?
    A Historical Review of the Distal Radius Fracture
    Anatomy of the Wrist
    Biomechanics and Kinematics of the Wrist
    Epidemiology
    Distal Radius Fractures and Osteoporosis
    Outcome Assessment After Distal Radius Fractures
    Medicolegal Aspects of Distal Radius Fractures
    Imaging
    Classification Distal Radius Fractures
    How to Assess Fracture Instability
    Pharmacologic Treatment of Distal Radial Fractures
    Flow Chart for Treatment: A Standardized Treatment Program as an Aid in Primary Treatment of Distal Radius Fractures
    The Clinical Dilemma: Nonoperative or Operative Treatment
    Clinical Diagnosis, Closed Reduction, and Plaster
    Closed Re-reduction: Is It an Alternative
    Closed Reduction and External Fixation of Unstable Distal Radius Fractures
    Closed Reduction and Percutaneous Pinning
    Closed Reduction and Intramedullary Fixation of Distal Radius Fractures
    Closed Reduction and External Fixation or Open Reduction and Volar Internal Fixation: The Clinical Dilemma
    Combined External Fixation and Internal Fixation
    Open Reduction and Volar Plating: Surgical Guide
    When Fixed-Angle Volar Plates Are Not Enough: Alternative Fixation Methods in Problem Fractures
    Die-Punch Fractures: Open and Arthroscopy-Assisted Fixation
    Arthroscopy in Distal Radius Fractures
    Associated Injuries in Distal Radius Fractures
    Radial Styloid Fractures and Associated Carpal Injuries
    Acute Injuries Around the Distal Ulna
    Bone Substitutes, Grafts and Cement
    The Elderly Osteoporotic Patient
    Rehabilitation
    Complications: An Overview
    Nerve Entrapments and Nerve Injuries in Distal Radius Fractures
    Tendon Complications of Distal Radial Fractures
    Complex Regional Pain Syndrome
    Compartment Syndrome of the Forearm
    Extra-articular Malunion of the Radius; Osteotomy of the Radius
    Ulnar Shortening Osteotomy After Distal Radius Fracture
    Intra-articular Malunion
    Distal Radius Fractures and Secondary Carpal Dysfunction
    Secondary Osteoarthrosis: Partial or Total Arthrodesis Versus Wrist Arthroplasty
    Secondary DRU Joint Problems Instability, Nonunion Styloid, and Ulnocarpal Abutment
    Salvage Procedures to the DRU Joint
    Wrist Denervation
    Associated Fractures of the Distal Ulna
    Galeazzi's Fracture and Essex-Lopresti Injuries: Dislocation Fractures of the Forearm
    Distal Radius Fractures in Children.
    Digital Access Springer 2014
  • Digital
    edited by Jesse Jupiter, Michael Chammas, editor-in-chief: Geert Alexander Buijze.
    Summary: Edited and authored by leading international experts, Distal Radius Fractures: Evidence-Based Management provides a state-of-the-art overview of diagnosis and management based on today's best practices. Each chapter focuses on one key issue, offering a challenging case and then questioning the reader in an engaging fashion to provide the best available evidence on each topic. Practical and easy to read, this innovative text is a useful resource for all residents, physicians and surgeons who manage fractures. Combines current best practices with the knowledge and experience of a global team of expert contributing authors, with a focus on practical use in applying the evidence. Covers need-to-know topics such as anatomy and biomechanics, diagnostic management, acute fracture management, management of pediatric and elderly fractures, and more. Includes valuable case scenarios, technical tips and tricks, and pearls and pitfalls. Features high-quality illustrations including CT scans, x-rays, and clinical photographs. Consolidates the latest evidence on distal radius fractures into one convenient resource. Enhanced eBook version included with purchase, which allows you to access all of the text, figures, and references from the book on a variety of devices.

    Contents:
    Principles of evidence-based management of distal radius fractures
    Epidemiology of distal radius fractures
    Surgical anatomy of the distal radius
    Biomechanics of distal radius fractures
    Radiographic parameters of distal radius fractures
    Advanced imaging in distal radius fractures
    Closed reduction and immobilization of displaced distal radius fractures
    Surgical versus conservative interventions for displaced distal radius fractures
    Predictors of instability and secondary displacement after conservatively managed distal radius fractures
    Minimally invasive plate osteosynthesis of distal radius fractures
    Volar, dorsal, and/or radial plating
    Comminuted articular distal radius fractures
    Extra-articular distal radius fractures with metaphyseal comminution
    Bone graft (substitutes) in distal radius fractures
    Arthroscopic-assisted treatment of distal radius fractures
    Simultaneous fractures of the distal radius and scaphoid
    Galeazzi fracture dislocations
    Diagnosis and treatment of an Essex-Lopresti injury
    Acute distal radioulnar joint instability
    Distal ulnar fractures concomitant with distal radius fractures
    Persistent ulnar-sided wrist pain after distal radius fracture
    Association between radiological and patient-reported outcomes
    Rehabilitation protocols after distal radius fracture
    Complex regional pain syndrome in distal radius fractures
    Pediatric distal radius fractures
    Pediatric forearm fractures
    Distal radius fracture fixation in the elderly
    Prevention of distal radius fractures
    Diagnosing the malunited distal radius
    Treatment of the extraarticular malunited distal radius
    Treatment of the intraarticular malunited distal radius
    Three-dimensional planning and surgical guidance of malunion correction
    Nonunion of distal radius fractures
    Tendon ruptures after distal radius fracture
    Chronic DRUJ instability after distal radius fractures
    Posttraumatic DRUJ arthritis
    Posttraumatic radiocarpal arthritis
    Wrist contracture after distal radius fractures.
    Digital Access
    Provider
    Version
    ScienceDirect
    ClinicalKey
  • Digital
    editor-in-chief, Francisco del Piñal ; co-editors, Max Haerle, Hermann Krimmer.
    Summary: "Hand and wrist fractures account for millions of emergency room visits annually. The extraordinary importance of these structures in activities of daily living necessitates great surgical competence in repairing fractures so as to preserve the vast range of motion and utility of this functional anatomic unit. The management theory and techniques for these fractures have seen dramatic changes in the last few decades. This new volume brings together all currently established operative techniques for distal radius fractures, explained in detail and highly illustrated, step by step, with a wealth of brilliant figures and diagrams. Key Features: Comprehensive coverage of all types of injury as well as all the evidence-based therapeutic surgical options. State-of-the-art management of carpal instability, anterior and dorsal rim fractures, radiocarpal dislocation, malunion, and much more. Includes coverage of ligamentous injuries. Contributions by numerous world-renowned surgeons This book is essential for all surgeons in training in orthopaedic surgery and in plastic surgery and highly useful to experienced surgeons"-- Provided by publisher.

    Contents:
    Anatomy of the Fracture / Simon MacLean, Gregory Bain
    Radiology of the Fractured Radius / Mark Ross, Patrick Groarke
    Patient-Accident-Fracture Classification of Acute Distal Radius Fractures in Adults / Guillaume Herzberg, Thais Galissard, Marion Burnier
    Distal Radius Fracture: The Evidence / Tracy Webber, Tamara D. Rozental
    Orthopaedic Treatment: When? / David Warwick, Oliver Townsend
    Mini Approaches / Gustavo Mantovani Ruggiero
    Spanning Plates / Mitchell G. Eichhorn, Scott G. Edwards
    Arthroscopic Management / Yukio Abe
    Anterior Rim Fractures / Jorge L. Orbay, Gabriel Pertierra
    Dorsal Rim Distal Radius Fractures with Radiocarpal Fracture-Dislocation / Rohit Garg, Jesse Jupiter
    Multiplanar Fixation in Severe Articular Fractures / Peter C. Rhee, Alexander Y. Shin
    Management of Wrist Open Fractures and Bone Defects / Rames Mattar Junior, Emygdio Jose Leomil de Paula, Luciano Ruiz Torres, Tiago Guedes da Motta Mattar, Gustavo Bersani Silva
    Radiocarpal Dislocation / Mark Henry
    Common Errors of Volar Plate Fixation / Robert J. Medoff, James M. Saucedo
    Distal Ulna Fractures / Christopher Klifto, David Ruch
    Distal Radioulnar Joint Instability Associated with Distal Radius Fractures / Shohei Omokawa, Takamasa Shimizu, Kenji Kawamura, Tadanobu Onishi
    Distal Radius Fracture in the Elderly / Rohit Arora, Markus Gabl
    Extra-articular Malunion / Karl-Josef Prommersberger
    Arthroscopic-Guided Osteotomy for Intra-articular Malunion / Francisco del Piñal
    Newer Technologies on Managing Distal Radius Fractures / Ladislav Nagy
    Distal Radius in Children and Growth Disturbances / Alexandria L. Case, Joshua M. Abzug
    Open Surgery for Chronic Scapholunate Injury / Dirck Ananos, Marc Garcia-Elias
    Arthroscopic Scapholunate Repair / Max Haerle, Christophe Mathoulin
    Treatment of Lunotriquetral Injuries / Benjamin F. Plucknette, Haroon M. Hussain, Lee Osterman
    Arthroscopic Management of Perilunate Dislocation and Fracture Dislocation / Jae Woo Shim, Jong-Pil Kim, Min Jong Park
    Radiocarpal Pain and Stiffness / Christoph Pezzei, Stefan Quadlbauer
    Ulnar Pain and Pronosupination Losses / Riccardo Luchetti, Andrea Atzei
    Chronic Distal Radioulnar Joint Instability / Michael C. K. Mak, Pak-Cheong Ho
    Digital Access
    Provider
    Version
    Thieme-Connect
    Thieme MedOne Plastic Surgery
  • Digital
    Peter J. Papadakos, Stephen Bertman, editors.
    Summary: Examining-room computers require doctors to record detailed data about their patients, yet reduce the time clinicians can spend listening attentively to the very people they are trying to help. This book presents original essays by distinguished experts in their fields, addressing such critical problems and making an urgent case for reform, because while electronic technology has revolutionized the practice of medicine, it also poses a unique challenge to health care. Smartphones in the hands of doctors and nurses have become dangerously seductive devices that can endanger their patients. Distracted Doctoring is written for anesthesiologists and surgeons, as well as general practitioners, nurses, and health care administrators and students. Chapters include Electronic Challenges to Patient Safety and Care; Distraction, Disengagement, and the Purpose of Medicine; and Managing Distractions through Advocacy, Education, and Change.

    Contents:
    Introduction : the problem of distracted doctoring / Peter J. Papadakos and Stephen Bertman
    Medicine enters the computer age / Lekshmi Santhosh and Raman Khanna
    Electronic challenges to patient safety and care / Stephen Bertman
    Addiction to technology and speed / Stephen Bertman
    Note to my doctor : lessons from fifty years of distracted driving research / Paul Atchley
    Distraction, disengagement, and the purpose of medicine / David Loxterkamp
    Taking time to truly listen to our patients / Deepthiman Gowda
    When it comes to the physician-patient-computer relationship, the "eyes" have it / Richard Frankel
    Impact of EMRs on communication within the doctor-patient relationship / Wei Wei Lee and Maria Lolita Alkureishi
    Physician dissatisfaction, stress, and burnout, and their impact on patient care / Alan H. Rosenstein
    Distractions in the operating room / Michelle A. Feil
    Risk reduction and vigilance in anesthesia / Roy G. Soto, Mallika Thampy, and Sara Neves
    Managing distractions through advocacy, education, and change / Donna A. Ford
    Electronic devices as potential sources of biological contamination / Roy H. Constantine
    Digital distraction and legal risk / James E. Szalados
    Electronic etiquette : a curriculum for health professionals / Peter J. Papadakos
    Mindful practitioners, mindful teams, and mindful organizations : attending to the core tasks of medicine / Ronald M. Epstein
    Afterword : "Physician, Heal Thyself, and Make Haste, Slowly."
    Digital Access Springer 2017
  • Digital
    Jenara Nerenberg.
    Summary: "A paradigm-shifting study of neurodivergent women-those with ADHD, autism, and other sensory processing differences-exploring why these traits are overlooked in women and how society benefits from allowing their unique strengths to flourish As a successful, Harvard- and Berkeley-educated writer, entrepreneur, and devoted mother, Jenara Nerenberg was shocked to discover that her "symptoms" that were only ever labeled as anxiety were considered autistic and ADHD. Being a journalist, she dove into the research and uncovered neurodiversity-a framework that moves away from pathologizing "abnormal" versus "normal" brains and instead recognizes the vast diversity of our mental makeups. Divergent Mind is a long-overdue, much-needed answer for women who have a deep sense that they are "different." Sharing real stories from women with ADHD, autism, synesthesia, misophonia, and more, Nerenberg explores how these brain variances present differently in women and dispels widely held misconceptions. She also offers a path forward, describing practical changes in how we can communicate, design our surroundings, and better support divergent minds. When we allow our wide variety of brain makeups to flourish, we create a better tomorrow for us all"-- Provided by publisher.
    Digital Access 2020
    Limited to 1 simultaneous userSUNet ID login required
  • Digital
    Dana A. Telem, Colin A. Martin, editors.
    Summary: This book comprehensively covers diversity, equity and inclusion (DEI) in the context of daily surgical practice. Through real-life illustrative case scenarios and experiences, this book explores DEI and its impact on academic surgery, career development, and clinical practice. Each chapter highlights a commonly encountered scenario and features extensive guidance on how to address each challenge secondary to both implicit explicit biases as well as detailing how to implement best practices. Diversity, Equity and Inclusion provides a detailed guide to the best practices and challenges associated with implementing DEI in day to day surgical practice and is a valuable resource for all surgical practitioners looking for a guide on how to successfully implement DEI strategies into daily clinical practice.

    Contents:
    Setting the Stage: What is Diversity, Equity and Inclusion?
    Best Practices in Recruitment and Retention
    Advancement and Leadership Development
    Mentorship and Sponsorship
    Research track and focus
    Selecting one's scope of practice
    Selecting one's type of practice
    Alternative Paths
    Patient Bias and the Surgeon
    Gender and Surgery
    Race/Ethnicity and Surgery
    Sexual Identity and Surgery
    Physical or Intellectual Disability and Surgery. .
    Digital Access Springer 2021
  • Digital
    Marcus L. Martin, Sheryl L. Heron, Lisa Moreno-Walton, editors ; Anna Walker Jones, managing editor.
    Contents:
    Defining Diversity in Quality Care
    Racial/Ethnic Healthcare Disparities and Inequities: Historical Perspectives
    Educating Medical Professionals to Deliver Quality Health Care to Diverse Patient Populations
    Culturally Competent Faculty
    Culturally Sensitive Care: A Review of Models & Educational Methods
    Interpreter Services
    The Patient-Physician Clinical Encounter
    Spiritual Care Services in Emergency Medicine
    Lesbian, Gay, or Bisexual (LGB): Caring with Quality and Compassion
    Culturally Competent Care of the Transgender Patient
    Looking Past Labels: Effective Care of the Psychiatric Patient
    Disability and Access
    Racial and Ethnic Disparities in the Emergency Department: A Public Health Perspective
    Vulnerable Populations: The Homeless and Incarcerated
    Vulnerable Populations: The Elderly
    Vulnerable Populations: Children
    Religio-cultural Consideration When Providing Healthcare to American Muslims
    Disparities and Diversity in Biomedical Research
    Cultural Competency Case Studies: Transitional Introduction
    Case 1: African-American Infant and Family
    Case 2: Cambodian Refugee
    Case 3: Sickle Cell Crisis
    Case 4: Mongolian Spots
    Case 5: Death Disclosure
    Case 6: Coin Rubbing
    Case 7: Toxic Ingestion
    Case 8: Adolescent Indian Male Sikh
    Case 9: Intimate Partner Violence in the Gay Community
    Case 10: West Indian/Caribbean
    Case 11: American Indian
    Case 12: Spiritualism in the Latino Community
    Case 13: Islamic Patient
    Case 14: Pediatric Pain.
    Digital Access Springer 2016
  • Digital
    Steve H. Koh, Gabriela G. Mejia, Hilary M. Gould, editors.
    Summary: This book presents an extensive collection of high-yield case vignettes with recommendations for a comprehensive approach to cultural psychiatry. Culture is defined from an anthropological perspective, with an emphasis on aspects of culture beyond race, ethnicity, and other traditional demographic categories. The goal of this book is to offer clinical applications of cultural psychiatry via examination of special populations, systems, and settings. With ever-changing geopolitical environments, institutional structures, and sociodynamics, attention and consideration of context is paramount. Theoretical models and specific frameworks for evaluating cultural influence on the manifestation, development, and treatment response of mental health illnesses are presented. The chapters are organized to showcase different ways in which culture plays into everyday clinical practice. Emphasis is placed on the full sum of the care delivery transaction within a larger context, including public and community systems of care. Real-world case examples are discussed in each chapter to help contextualize the dynamic nature that culture plays in practice across inpatient and outpatient settings. Each case presents with relevant academic and historical background and practical operational advice for psychiatrists providing care within these respective communities. The authors address diverse clinical cases related to refugee and asylum seekers, military service members, survivors of human trafficking, incarcerated populations, and more. Training recommendations and best practices are outlined including psychopharmacology, psychosocial treatments, and cultural adaptations to evidence based treatments. Diversity in Action: Case Studies in Cultural Psychiatry is a useful resource for all psychiatrists, psychologists, general practitioners, social workers, nurses, administrators, public policy officials, and all medical professionals working with a culturally diverse subset of patients seeking mental health.

    Contents:
    Introduction
    Survivors of Torture
    Survivors of Human Trafficking
    Survivors of Combat Trauma
    Co-Occurring Disorders
    Telepsychiatry to Rural Populations
    Religion, Spirituality, and Mental Health
    Biculturalism: the case of two North American neighbors
    Correctional Psychiatry
    Shifting Gears: Cultural Assimilation into Primary Care
    Psychiatric Care in Residential Care Environments.
    Digital Access Springer 2022
  • Digital
    Pierre-Marie Bosc, Jean-Michel Sourisseau, Philippe Bonnal, Pierre Gasselin, Élodie Valette, Jean-François Bélières, editors.
    Summary: In contemporary times where farming models are challenged through deep transformations of agricultural organizations and markets, this books proposes a new visit of the diversity of family forms of production to explore their current transformations all over the world. By adopting a comprehensive perspective it allows bringing together several dimensions often studied separately: linkages with markets, territorial development, labour mobility through migrations and livelihood strategies, farms? autonomy, and food security, as well as the many ways of collective action and the role of public policies. The book relies on 18 case studies in the five continents. All were driven with a single and original methodological framework, inspired by the Sustainable Rural Livelihoods. The SRL initial framework was reshaped and adapted to allow each author to fine-tune "what makes family," to understand family labour adaptations to their environment, and to align them with territorial dynamics and public policies in each national situation. Co-written by a network of researchers, this book deepens scientific knowledge on family farming around the world, and at the same time it contributes to test and improve a methodological framework adapted to analyse and of observe rural dynamics. It is dedicated to researchers, teachers and students, agronomists, economists, geographers, sociologists and historians but also experts and practitioners in agricultural and rural development. More widely, NGOs and any citizen willing to understand the family farming's issues in different social contexts, should also find interest in reading it.

    Contents:
    Foreword
    Introduction
    Non-Market rationales, an?archaism? worth revisiting
    Introduction
    Family farming in Polish Podlasie: anachronism or overlooked potential?
    Urban and peri-urban agriculture: dairy farms in Cairo, Egypt
    Integration into international markets of family cotton farms in Mali
    The fragility of the sedentarization of a pastoral Fula population in Benin
    Local anchoring and migration as two faces of the same coin
    Introduction
    Diversified multi-localized family farming in Nicaragua
    The iony moment and the Indian farmers of Ecuador
    Agriculture in southern Mozambique: an activity based on migrations for work
    At the limits of family agriculture: family business forms of production?
    Introduction
    Between firms and family business farms: small transitory family plantations in Indonesia
    Family farming in Brazil, modernized and integrated
    Agricultural family enterprises, territories and politics in Argentina
    Diversification of activities between strategies of survival and accumulation
    Introduction
    Family farming confronted by drought and liberalization in Senegal
    Long-term accumulation strategies and family farms in Cameroon
    The uncertain market integration of family farms in Madagascar
    Organization of family in between a collective asset and the limitations of individual strategies
    Introduction
    From the big to the small family in Burkina Faso: disrupted generations and statuses
    A family and its system of pastoral farming without borders, between Niger, Chad and Nigeria
    Beyond family farming: determining political and territorial issues
    Introduction
    Fragmentation of irrigated family farms in southern India
    On the roof of the world, the pastoralists of the Tibetan plateau confronted by change
    Family agriculture in contemporary Kanak society
    Conclusion: Methodological and conceptual contributions
    References
    List of authors.
    Digital Access Springer 2018
  • Digital
    Diane L. Dixon.
    Summary: "This book is about the lived experiences on the executive path of 12 racially and ethnically diverse hospital and health system CEOs. It is based on interviews. It seeks to learn from the collective wisdom of all the executives to provide a unique glimpse, from their perspectives, into what it takes to navigate the challenges and opportunities of the executive path to the C-suite"-- Provided by publisher.

    Contents:
    Backgrounds Are the Foundation
    Reflections on Race and Ethnicity
    Positive Personal Qualities
    The Power of Relationships
    The Essential Role of Sponsorship
    The Executive Path : A Journey, Not a Ladder
    Maximizing Career Mobility
    When the Going Gets Tough
    Leadership Makes the Difference
    Discerning What Matters Most
    Closing Thoughts for the Journey.
  • Digital
    editors, Michael W. Mulholland, Erika Adams Newman.
    Summary: "The surgical treatment of human disease is inherently complex. Patients present with symptoms or disabilities that may relate to a variety of underlying causes. In evaluating those symptoms, modern medicine provides multiple diagnostic modalities that may be applied but in proper sequence and economically. Once a diagnosis is secured, treatment recommendations may include both surgical and nonsurgical therapies. In turn, when operative treatment is recommended, a variety of approaches--open, laparoscopic, robotic--are available, each with its particular efficacy, risk, and cost. In addition, surgical patients are inherently variable. Each patient has a unique set of comorbidities and an individual biological milieu. Each requires personalized treatment. These are the complexities that surgeons confront every day, and for which creativity and diversity of thought are essential. Exciting new research demonstrates that problems characterized by complexity and high variability are best solved by teams intentionally constructed to maximize diversity. The premise of The Diversity Promise: Success in Academic Surgery and Medicine Through Diversity, Equity, and Inclusion is that demonstrable advantages come from the intentional mixture of talented people in a stimulating environment. Maximizing performance depends upon teamwork but teams constructed and enabled in a specific way. To be truly impactful, team members must be both talented and diverse. People have differing life experiences based upon age, race, gender, religious belief, and myriad other factors. These experiences, in turn, produce differing perspectives that create a strong competitive advantage for diverse teams."-- From preface.

    Contents:
    Building an open and inclusive enironment for faculty
    Attracting talented medical students
    Developing talent in surgery residents.
    Digital Access
    Provider
    Version
    Ovid
    LWW Health Library
  • Print
    Karen Speerstra, Herbert Anderson ; foreword by Ira Byock, MD.
    Summary: "The Divine Art of Dying" explores the unique moment when seriously ill people choose to turn toward death. Combining personal stories with solid research on palliative and hospice care, it provides a well-integrated look at the spiritual dimensions of living fully when death is near. Filled with insights from the world's great wisdom traditions along with references from literature, movies, and current culture, it helps identify the life decisions the dying one and his or her loved ones must make, and what their caregivers can expect.
    Print Access Request
    Location
    Version
    Call Number
    Items
    Books: General Collection (Downstairs)
    BL504 .S66 2014
    1
  • Digital
    Olaf Rusoke-Dierich.
    Summary: "This book is the very first to cover the decompression theory in detail. It gives many information on all topics of the diving medicine, and is richly and uniquely illustrated. It offers a good guideline of high quality practice in diving medicine. The author provides a very structured and easy to understand book, by covering all aspects of the diving medicine, such as equipment, physiology, and related issues as gas intoxications, venomous animals or damages that can occur in the diving practice. Relevant physiological and anatomical illustrations enlight even complex topics. The Diving medicine book will appeal to health experts like doctors and nurses, but also to diving schools and teachers"-- Provided by publisher.
    Digital Access Springer 2018
  • Digital
    by Elissa P. Benedek, Samantha A. Huettner.
    Summary: This book explores the impact of divorce on adolescents and young adults, drawing on anecdotes from the authors' own medical and law practices to illustrate how parents' decision-making can powerfully impact their children's well-being before, during, and after a divorce -- even into adulthood.

    Contents:
    Cover; Half Title; Title Page; Copyright; Contents; Acknowledgments;
    Chapter 1 It's A Different World Now;
    Chapter 2 The Decision to Divorce: Putting Children First;
    Chapter 3 How to Tell Your Children About Your Divorce;
    Chapter 4 Minimizing the Effects of the Legal Process on Your Children;
    Chapter 5 Impact of Divorce on Children;
    Chapter 6 Impact of Divorce on Parenting;
    Chapter 7 Parenting Time and Related Issues;
    Chapter 8 Special Parenting Issues;
    Chapter 9 Parenting Techniques to Build Your Child's Self-Esteem;
    Chapter 10 Discipline as Guide and Teacher
    Chapter 11 Making Use of Others' Support;
    Chapter 12 Danger Signals: When Is Professional Help Needed?;
    Chapter 13 Adjusting to Life in a Stepfamily;
    Chapter 14 Questions and Answers;
    Chapter 15 Additional Resources and Helpful Organizations for Divorced Parents; Index; Back Cover
  • Digital
    S. B. Bhattacharyya.
    Summary: This book is a do-it-yourself guide for clinicians who wish to set up and run a telemedicine facility of their own. The contents are largely based on the understanding and experience gained by the author as a practising physician, management post-graduate (capstone thesis was on telemedicine) and as a business architect for digital health systems over more than thirty years. Full of management techniques, tricks and tips written in an easy-to-follow manner, this book provides sufficient information to clinicians looking to leverage telemedicine to augment their range of service offerings that would lead to increased levels of patient satisfaction. Various aspects related to definitions, technology, infrastructure, methodologies and legal issues for setting up and running telemedicine services have been dealt with to sufficient depths for the readers to help grasp the issues involved. Sections on privacy, confidentiality and data integrity have been provided to help allay the many concerns the readers might have in those regards. Additionally, financial evaluations based on realistic-enough figures have been used to demonstrate that telemedicine is a viable option financially. Although meant primarily for medical doctors, any care provider including institutional will be able to use the contents to plan, design, set up and run telemedicine services that they feel would benefit those who receive their care.

    Contents:
    Telemedicine
    Telemedicine Services
    Infrastructural Requirements
    Technological Requirements
    All Services
    Overview & General Principles
    Teleconsultation
    Telemonitoring
    Remote Care
    Management Aspects
    Legal Aspects.
    Digital Access Springer 2017
  • Digital
    A. Tucker Gleason, Bradley W. Kesser.
    Summary: "Get a quick, expert overview of dizziness and vertigo from childhood through old age with this concise, practical resource. Drs. Bradley W. Kesser and Tucker Gleason have assembled a leading team of experts to address timely clinical topics of interest to otolarynologists and other health care providers who see patients with these common problems. Covers key topics such as the clinical exam and diagnostic techniques, assessment and differential diagnosis in the pediatric population, dizziness and vertigo in the adolescent and the elderly, evaluation of dizziness in the litigating patient, vHIT, positional vertigo in all age groups, vestibular neuritis, migraine-associated vertigo, Meniere's disease, medication-related dizziness in the older adult, and more. Includes information on dizziness demographics and population health, as well as development of the vestibular system and balance function. Consolidates today's available information and experience in this important area into one convenient resource"--Publisher's description.

    Contents:
    Section 1: Introduction to dizziness. Dizziness demographics and population health
    Clinical examination of the dizzy patient in the context of contemporary diagnostic techniques
    Section 2: Pediatric. Development of the vestibular system and balance function: differential diagnosis in the pediatric population
    Assessment techniques for vestibular evaluation in pediatric patients
    The predominant forms of vertigo in children and their associated findings on balance function testing
    Section 3: Adolescent and adult. Dizziness and vertigo in the adolescent
    Evaluation of dizziness in the litigating patient
    vHIT
    Positional vertigo: as occurs across all age groups
    Vestibular neuritis
    Migraine-associated vertigo
    Superior canal dehiscence
    Meniere's disease: a challenging and relentless disorder
    Uncommon causes of disequilibrium in the adult
    Section 4: Elderly. Baroreflexes
    Vertebrobasilar infarcts and ischemia
    Dizziness in the elderly
    Medication-related dizziness in the older adult
    Vestibular rehabilitation of older adults with dizziness.
    Digital Access ClinicalKey 2018
  • Digital
    Hiroyoshi Ariga, Sanae M.M. Iguchi-Ariga, editors.
    Summary: This book reviews the functions and roles of DJ-1 in various oxidative stress-related diseases and applications of DJ-1 and its binding compounds to the diseases. The DJ-1 gene was first found to be a novel oncogene in 1997 and later, in 2003, also found to be a causative gene for a familial form of Parkinson's disease (PD), park7. The DJ-1 gene is therefore the first gene discovered that is known to cause cancer and neurodenegerative diseases, including PD. The research field has expanded as the research has developed. Thus this volume begins with a general introduction of DJ-1, and explains the history and research development to understand the following chapters. Those chapters present the roles of DJ-1 in various oxidative stress-related diseases such as neurodegenerative diseases, as well as cancer, diabetes, and fertility. Moreover, several chapters present evidence that DJ-1 is useful for therapeutic strategies against these diseases. The reader will discover that DJ-1 is a promising protein both for basic cell biology and for the mechanism and therapy for oxidative stress-related diseases. .

    Contents:
    Introduction/overview
    Structural biology of the DJ-1 superfamily
    Expression of DJ-1 in patients with neurodegenerative diseases
    DJ-1 as an oncogene and its clinical significance
    Role of DJ-1 in fertilization
    Anti-oxidative stress function of DJ-1
    Transcriptional regulation of DJ-1
    Regulation of signal transduction by DJ-1
    Protein repair by DJ-1 from glycation by glyoxal and methylglyoxal
    DJ-1 as a biomarker of Parkinson's disease
    Roles of DJ-1 in diabetes mellitus
    Therapeutic activities of DJ-1 and its binding compounds against neurodegenerative diseases
    DJ-1 as an oncogene and promising target for cancer chemotherapy.
    Digital Access Springer 2017
  • Digital
    Stefan Jurga, Jan Barciszewski, editors.
    Summary: This book reviews the chemical, regulatory, and physiological mechanisms of protein arginine and lysine methyltransferases, as well as nucleic acid methylations and methylating enzymes. Protein and nucleic acid methylation play key and diverse roles in cellular signalling and regulating macromolecular cell functions. Protein arginine and lysine methyltransferases are the predominant enzymes that catalyse S-adenosylmethionine (SAM)-dependent methylation of protein substrates. These enzymes catalyse a nucleophilic substitution of a methyl group to an arginine or lysine side chain nitrogen (N) atom. Cells also have additional protein methyltransferases, which target other amino acids in peptidyl side chains or N-termini and C-termini, such as glutamate, glutamine, and histidine. All these protein methyltransferases use a similar mechanism. In contrast, nucleic acids (DNA and RNA) are substrates for methylating enzymes, which employ various chemical mechanisms to methylate nucleosides at nitrogen (N), oxygen (O), and carbon (C) atoms. This book illustrates how, thanks to there ability to expand their repertoire of functions to the modified substrates, protein and nucleic acid methylation processes play a key role in cells.

    Contents:
    Chapter 1. Establishment, Erasure and Synthetic Reprogramming of DNA Methylation in Mammalian Cells.- Chapter 2. Origin and Mechanisms of DNA Methylation Dynamics in Cancers.- Chapter 3. CpG Islands Methylation Alterations in Cancer: Functionally Intriguing Security Locks, Useful Early Tumor Biomarkers.- Chapter 4. Histone and DNA Methylome in Neurodegenerative, Neuropsychiatric and Neurodevelopmental Disorders.- Chapter 5. DNA Methylation in Neuronal Development and Disease.- Chapter 6. Functional Implications of Dynamic DNA Methylation for the Developing, Aging and Diseased Brain.- Chapter 7. The Methylome of Bipolar Disorder: Evidence from Human and Animal Studies.- Chapter 8. DNA Methylation in Multiple Sclerosis.- Chapter 9. Early Life Stress and DNA Methylation.- Chapter 10. Regulation of 5-hydroxymethylcytosine Distribution by the TET Enzymes.- Chapter 11. Epigenetic Alterations: The Relation Between Occupational Exposure and Biological Effects in Humans.- Chapter 12. DNA Methylation: Biological Implications and Modulation of its Aberrant Dysregulation.- Chapter 13. Functions and Dynamics of Methylation in Eukaryotic mRNA.- Chapter 14. The Role of mRNA m6A in Regulation of Gene Expression.- Chapter 15. G9a and G9a-like Histone Methyltransferases and Their Effect on Cell Phenotype, Embryonic Development, and Human Disease.- Chapter 16. Biomolecular Recognition of Methylated Histones.- Chapter 17. The Role of Protein Lysine Methylation in the Regulation of Protein Function
    Looking Beyond the Histone Code.- Chapter 18. Secondary Structures of Histone H3 Proteins with Unmethylated and Methylated Lysine-4 and -9 Resiudes; Characterization Using Circular Dichroism Spectroscopy.- Chapter 19. Asymmetric Dimethylation on Arginine (ADMA) of Histones in Development, Differentiation and Disease.- Chapter 20. A Switch for Transcriptional Activation and Repression: Histone Arginine Methylation.- Chapter 21. Aberrant Epigenomic Regulatory Networks in Multiple Myeloma and Strategies for their Targeted Reversal.- Chapter 22. Metabolic Deregulations Affecting Chromatin Architecture: One-carbon Metabolism and Krebs Cycle Impact Histone Methylation.- Chapter 23. Histone Methylome of the Human Parasite Schistosoma Mansoni.
    Digital Access Springer 2019
  • Digital
    Atsushi Kaneda, Yu-ichi Tsukada, editors.
    Contents:
    DNA and histone methylation in epigenetics
    Part II: DNA methylation and cancer
    Part III: DNA and histone methylation-related events underlying cancer
    Part IV: DNA and histone methylation in particular types of cancer
    Part V: DNA and histone modifications in diagnosis and therapy of cancer
    Part VI: Future directions.
    Digital Access Springer 2017
  • Digital
    Vadim V. Demidov.
    Summary: This is the first book portraying to a wide readership many fields of DNA in the world of materials altogether in a single volume. The book provides underlying concepts and state-of-art developments in the emerging fields of DNA electronics, structural DNA nanotechnology, DNA computing and DNA data storage, DNA machines and nanorobots. Future possibilities of innovative DNA-based technologies, such as DNA cryptography, DNA identity tags, DNA nanostructures in biosensing and nanomedicine, as well as DNA-based nanoelectronics are all covered, too. This book is valuable for university students studying engineering and technology; biotech, nanotech, and medical device R & D managers, practitioners and investors; and IP analysts who would like to extend their background in advanced DNA technologies. It is nicely illustrated, which makes it very readable, and it conveys science and principles in a lively language to appeal to a broad audience, from professionals and academics to students and lay readers. Advance Praise for DNA Beyond Genes: "Most students of DNA, and lay readers as well, are interested in the absolutely essential role it plays in biology. However, the properties which make DNA the carrier of genetic information also make it an extraordinary material that can be used as the backbone for a wide variety of nanoengineering applications - these range from information storage and computation to molecular machines and devices to artfully designed logos and symbols. The perfect self-recognition of DNA sequences makes it an ideal building block to synthesize more and more elaborate constructions and imaginative scientists have probably only just scratched the surface of what can eventually be created. Here for the first time in this wonderful book Vadim Demidov explores the full range of the non-biological applications of DNA." Charles R. Cantor Professor Emeritus of Biomedical Engineering, Boston University Member of the USA National Academy of Sciences.

    Contents:
    Introduction: DNA basics (a primer on DNA)
    Hiding and storing messages and data in DNA
    DNA as a nanoscale building material
    DNA machines and nanobots
    DNA-based nanoelectronics
    Concluding remarks.
    Digital Access Springer 2020
  • Digital
    Seok-Yong Choi, Hyunju Ro, Hankuil Yi.
    Summary: This book offers step-by-step instruction on DNA cloning, defined as moving genes around plasmids, mutating genes, or mining new genes. The aim is to provide those new to the field with reliable and up-to-date practical guidance while at the same time conveying the scope for creativity. After a brief synopsis of the history of cloning, the fundamentals and prerequisites are explained, covering, for example, software, vectors commonly used in the lab, appropriate choice of restriction endonucleases, the preparation of agarose gels, competent cells, and LB agar plates, and procedures to be followed upon receipt of new plasmids. The remainder of the book is devoted to the clear description of methods and individual steps in cloning. Guidance is provided on the cut and paste method, DNA sequencing, direct sequencing, primer design, PCR-based gene insertion and deletion, epitope tag insertion, the use of RACE technology, BAC recombineering, and much, much more. Sources of error and a variety of techniques that make life considerably easier when cloning are also examined in detail.

    Contents:
    Part I. What is cloning?
    Chapter 1.1 Definition of cloning
    Chapter 1.2 Discovering a new gene
    Chapter 1.3 Cloning in the past
    Chapter 1.4 Cloning in the present
    Part II. A prerequisite for cloning
    Chapter 2.1 Software useful for cloning design
    Chapter 2.2 Vector, plasmid, construct and the Kozak consensus sequence
    Chapter 2.3 Multiple cloning sites (MCS)
    Chapter 2.4 Restriction endonucleases and star activity
    Chapter 2.5 Agarose gel electrophoresis
    Chapter 2.6 Pouring LB agar plates
    Chapter 2.7 Competent cells
    Chapter 2.8 The conversion of DNA mass into molar concentration
    Chapter 2.9 Upon receiving new plasmids
    Chapter 2.10 cDNA library
    Part III. The first step in cloning
    Chapter 3.1 Cut & paste
    Chapter 3.2 DNA sequencing and direct sequencing
    Chapter 3.3 PCR and nested PCR
    Chapter 3.4 Fill-in (Full & Partial)
    Chapter 3.5 Compatible cohesive ends
    Chapter 3.6 Methylation
    Chapter 3.7 Three-piece ligation
    Chapter 3.8 Site-directed mutagenesis
    Chapter 3.9 Structure of plant transformation vectors
    Chapter 3.10 Transformation of R. radiobacter
    Part IV. The next step of cloning
    Chapter 4.1 How to insert a DNA fragment into a gene
    Chapter 4.2 How to delete an internal region of a gene
    Chapter 4.3 How to insert an epitope tag into a gene
    Chapter 4.4 Translational fusion vs. transcriptional fusion
    Part V. The last steps of cloning
    Chapter 5.1 Method for cloning similar genes in different species
    Chapter 5.2 RACE (rapid amplification of cDNA ends)
    Chapter 5.3 BAC recombineering
    Chapter 5.4 Old trick: partial digestion
    Chapter 5.5 Modification of a vector
    Chapter 5.6 When you notice a frame shift mutation upon cloning
    Chapter 5.7 Reality of cloning: an extremely unlucky case
    Part VI. Methods that make your cloning life easier
    Chapter 6.1 TA cloning and production of a T-vector
    Chapter 6.2 TOPO TA cloning
    Chapter 6.3 Gateway cloning
    Chapter 6.4 Golden Gate Assembly for a modular cloning
    Chapter 6.5 In-Fusion Sequence and Ligation-Independent Cloning (In-Fusion SLIC)
    Chapter 6.6 T4 DNA Polymerase Sequence-and Ligation-Independent Cloning (T4 DNA Pol SLIC)
    Chapter 6.7 Non-template PCR cloning
    Part VII. Advice to cloners
    Chapter 7.1 When cloning is not going well
    Chapter 7.2 Keep your cloning data organized
    Appendix 1. Further readings
    Appendix 2. Abbreviations
    Appendix 3. Index.
    Digital Access Springer 2019
  • Digital
    edited by Svein Valla and Rahmi Lale.
    Contents:
    1. BioBrick assembly standards and techniques and associated software tools / Gunvor Røkke, Eirin Korvald, Jarle Pahr, Ove Øyås and Rahmi Lale
    2. Plasmid construction by SLIC or sequence and ligation- independent cloning / Ryan E. Hill and Julian J. Eaton-Rye
    3. Quick and clean cloning / Frank Thieme and Sylvestre Marillonnet
    4. Hierarchical ligation-independent assembly of PCR fragments / Jonathan L. Schmid-Burgk, Zhen Xie, and Yaakov Benenson
    5. USER-derived cloning methods and their primer design / Bo Salomonsen, Uffe H. Mortensen, and Barbara A. Halkier
    6. Application of the restriction-free (RF) cloning for multicomponents assembly / Yoav Peleg and Tamar Unger
    7. A single-tube assembly of DNA using the transfer-PCR (TPCR) platform / Ariel Erijman, Julia M. Shifman, and Yoav Peleg
    8. Circular polymerase extension cloning / Jiayuan Quan and Jingdong Tian
    9. Golden gate cloning / Carola Engler and Sylvestre Marillonnet
    10. Design and construction of multigenic constructs for plant biotechnology using the goldenbraid cloning strategy / Alejandro Sarrion-Perdigones, Jorge Palaci, Antonio Granell and Diego Orzaez
    11. FX cloning : a simple and robust high-throughput cloning method for protein expression / Eric R. Geertsma
    12. Minimum GC-rich sequences for overlap extension PCR and primer annealing / Mikiko Nakamura, Ayako Suzuki, Hisashi Hoshida and Rinji Akada
    13. Simple cloning and DNA assembly in Escherichia coli by prolonged overlap extension PCR / Chun You and Y.-H. Percival Zhang
    14. Combinatorial assembly of clone libraries using site-specific recombination / Vanessa E. Wall, Leslie A. Garvey, Jennifer L. Mehalko, Lauren V. Procter and Dominic Esposito
    15. Application of In-Fusion [trademark] cloning for the parallel construction of E. coli expression vectors / Louise E. Bird, Heather Rada, John Flanagan, Jonathan M. Diprose, Robert J.C. Gilbert and Raymond J. Owens
    16. Seamless ligation cloning extract (SLiCE) cloning method / Yongwei Zhang, Uwe Werling, and Winfried Edelmann
    17. j5 DNA assembly design automation / Nathan J. Hillson
    18. FastPCR software for PCR, in silico PCR, and oligonucleotide assembly and analysis / Ruslan Kalendar, David Lee, and Alan H. Schulman.
    Digital Access Springer 2014
  • Digital/Print
    edited by Jac A. Nickoloff and Merl F. Hoekstra.
    Contents:
    v. 1. DNA repair in prokaryotes and lower eukaryotes
    v. 2. DNA repair in higher eukaryotes
    v. 3. Advances from phage to humans.
    Digital Access
    Provider
    Version
    Springer
    Springer
    Print Access
    Location
    Version
    Call Number
    Items
    Stored offsite. Please request print.
    QH467 .D15
    1
    Books: General Collection (Downstairs)
    QH467 .D15
    2
  • Digital
    Hirak Ranjan Dash, Pankaj Shrivastava, Braja Kishore Mohapatra, Surajit Das, editors.
    Summary: This book describes the basics and various applications of DNA fingerprinting, including in actual case studies. The book is divided in four modules; Module 1: Basics of DNA Fingerprinting, Module 2: Applications of DNA Fingerprinting, Module 3: DNA Fingerprinting: Case Studies, and Module 4: Future of DNA Fingerprinting. Each module consists of 4 to 5 chapters, written by reputed researchers, academics and forensic scientists from around the globe. The respective chapters cover e.g. related fields, the tools and techniques used, various genotyping kits, real-world case studies, ancient DNA and wild life forensics, molecular diagnosis of human diseases, legal aspects, microbial forensics and the economics of the DNA fingerprinting technique. The book offers a practical guide for professionals, graduate and post-graduate students in the fields of Forensic Science, Medicine, Genetics, Anthropology, Microbiology, and Zoology. It also serves as a useful reference resource, summarizing major technological advances in the field of DNA fingerprinting, the problems faced in this field of science and possible new solutions to these problems. Presently, DNA fingerprinting is utilized in solving the majority of criminal cases; as such, the book is also helpful for investigating agencies, as it includes representative case studies.

    Contents:
    Module 1_ Basics of DNA Fingerprinting: Chapter 1. DNA Fingerprinting technique: Discovery, Advancements and Milestones
    Chapter 2. Genetic Basis of DNA Fingerprinting in Humans
    Chapter 3. Comparative Account of the DNA Fingerprinting Techniques: RFLP, STR Typing and NGS
    Module 2_ DNA Fingerprinting: Tools and Techniques:
    Chapter 4. Techniques involved in DNA Fingerprinting: Isolation, Quantification, PCR, Genotyping and Analysis
    Chapter 5. STR Typing and available Kits
    Chapter 6. In-silico techniques for analysis of genetic variation among individuals
    Chapter 7. Statistical tools and techniques in interpretation of DNA sequencing results
    Chapter 8. DNA fingerprinting with homologous multilocus probes and search for DNA markers
    Module 3_ Applications of Genetic Fingerprinting:
    Chapter 9. Analysis of Ancient DNA
    Chapter 10. Wild Life Forensics
    Chapter 11. Molecular Diagnosis of Human Genetic Diseases: Application of Genetic Fingerprinting
    Chapter 12. Precautions and Recommendations for DNA fingerprinting for forensic applications
    Chapter 13. Legal aspects of DNA fingerprinting
    Module 4_ DNA Fingerprinting: Case Studies: Chapter 14. Autosomal DNA Typing: Case Studies
    Chapter 15. Y-chromosome testing and case studies
    Chapter 16. Mitochondrial DNA typing with case studies
    Chapter 17. X-chromosome Analysis and Case Studies
    Chapter 18 SNP analysis and Case Studies.
    Digital Access Springer 2018
  • Digital/Print
    Albert Jeltsch, Renata Z. Jurkowska, editors.
    Contents:
    Mechanisms and biological roles of DNA methyltransferases and DNA methylation: from past achievements to future challenges / Renata Z. Jurkowska, Albert Jeltsch
    DNA and RNA pyrimidine nucleobase alkylation at the carbon-5 position / Yuri Motorin, Salifu Seidu-Larry, Mark Helm
    Bacterial DNA methylation and methylomes / Josep Casadesús
    Domain structure of the Dnmt1, Dnmt3a, and Dnmt3b DNA methyltransferases / Shoji Tajima, Isao Suetake, Kohei Takeshita, Atsushi Nakagawa, Hironobu Kimura
    Enzymology of mammalian DNA methyltransferases / Renata Z. Jurkowska, Albert Jeltsch
    Genetic studies on mammalian DNA methyltransferases / Jiameng Dan, Taiping Chen
    The role of DNA methylation in cancer / Ranjani Lakshminarasimhan, Gangning Liang
    Structure and mechanism of plant DNA methyltransferases / Jiamu Du
    DNA methylation and gene regulation in honeybees: from genome-wide analyses to obligatory epialleles / Laura Wedd, Ryszard Maleszka
    N6-methyladenine: a conserved and dynamic DNA mark / Zach Klapholz O'Brown, Eric Lieberman Greer
    Pathways of DNA demethylation / Wendy Dean
    Structure and function of TET enzymes / Xiaotong Yin, Yanhui Xu
    Proteins that read DNA methylation / Takashi Shimbo, Paul A. Wade
    DNA base flipping: a general mechanism for writing, reading, and erasing DNA modifications / Samuel Hong, Xiaodong Cheng
    Current and emerging technologies for the analysis of the genome-wide and locus-specific DNA methylation patterns / J̲örg Tost
    DNA methyltransferase inhibitors: development and applications / Marie Lopez, Ludovic Halby, Paola B. Arimondo
    Rewriting DNA methylation signatures at will: the curable genome within reach? / Sabine Stolzenburg, Désirée Goubert, Marianne G. Rots
    Engineering and directed evolution of DNA methyltransferases / Paola Laurino, Liat Rockah-Shmuel, Dan S. Tawfik
    DNA labeling using DNA methyltransferases / MiglėTomkuvienė, Edita Kriukienė, Saulius Klimaašuskas.
    Digital Access Springer 2016
  • Digital
    edited by Timothy W. Bredy.
    Summary: Begins with an historical overview of the early discoveries surrounding DNA methylation in the mammalian brain and then explores the evidence supporting a role for this epigenetic mechanism in controlling gene expression programs across the lifespan in both normal and diseased states. Chapters describe new directions and technological advances, and provide an overview of what the future holds for this exciting new field. This book is ideal for medical, graduate and advanced undergraduate students, but is also a great resource for researchers who need a broad introduction to the dynamic nature of DNA that sheds light on evolving concepts of gene-environment interaction and their effects on adaptation and neuropsychiatric disease.

    Contents:
    Preface
    History and modern view on DNA modifications in the brain / B.F. Vanyushin and V.V. Ashapkin
    Approaches to detecting DNA base modification in the brain / X. Li and W. Wei
    Active DNA demethylation in neurodevelopment / Y. Kang, Z. Wang and P. Jin
    TET and 5hmC in neurodevelopment and the adult brain / M. Fasolino, S.A. Welsh and Z. Zhou
    Beyond mCG : DNA methylation in noncanonical sequence context / E.A. Mukamel and R. Lister
    DNA modifications and memory / J.J. Day
    Measuring CpG methylation by SMRT sequencing / Y. Suzuki, J. Korlach and S. Morishita
    Epigenetic modifications of DNA and drug addiction / J. Feng and E.J. Nestler
    What does the future hold for the study of nucleic acid modifications in the brain? / P.R. Marshall and T.W. Bredy.
    Digital Access ScienceDirect 2017
  • Digital
    edited by Benoit P. Leblanc and Sebastien Rodrigue.
    Contents:
    Electrophoretic mobility shift assay using radiolabeled DNA probes
    In vitro DNase i footprinting
    Determining the architecture of a protein-DNA complex by combining FeBABE cleavage analyses, 3-D printed structures, and the ICM molsoft program
    In cellulo DNA analysis: LMPCR footprinting
    Southwestern blotting assay
    Single-molecule approaches for the characterization of riboswitch folding mechanisms
    Probing of nascent riboswitch transcripts
    Functional studies of DNA-protein interactions using fret techniques
    Precise identification of genome-wide transcription start sites in bacteria by 5'-rapid amplification of cDNA ends (5'-RACE)
    Analysis of DNA supercoiling induced by DNA-protein interactions
    Precise identification of DNA-binding proteins genomic location by exonuclease coupled chromatin immunoprecipitation (ChIP-exo)
    The cruciform DNA mobility shift assay: A tool to study proteins that recognize bent DNA
    Individual and sequential chromatin immunoprecipitation protocols
    Chromatin endogenous cleavage (ChEC) as a method to quantify protein interaction with genomic DNA in saccharomyces cerevisiae
    Selection and validation of spacer sequences for CRISPR-Cas9 genome editing and transcription regulation in bacteria
    Detection of short-range DNA interactions in mammalian cells using high-resolution circular chromosome conformation capture coupled to deep sequencing
    Global mapping of open chromatin regulatory elements by formaldehyde-assisted isolation of regulatory elements followed by sequencing (FAIRE-seq)
    Aggregate and heatmap representations of genome-wide localization data using VAP, a versatile aggregate profiler
    Circular dichroism for the analysis of protein-DNA interactions
    Quantitative investigation of protein-nucleic acid interactions by biosensor surface plasmon resonance
    Identification of nucleic acid high affinity binding sequences of proteins by SELEX.
    Digital Access Springer 2015
  • Print
    edited by Errol C. Friedberg and Philip C. Hanawalt.
    Print Access Request
    Location
    Version
    Call Number
    Items
    Stored offsite. Please request print.
    QH467 .D16
    3
  • Digital
    Chikako Nishigori, Kaoru Sugasawa, editors.
    Summary: This book focuses on the clinical aspects of DNA repair disorders. Nucleotide excision repair is an important pathway for humans, as it is involved in biologically fundamental functions. This work presents clinical features together with the pathogenesis of DNA repair disorders such as Xertoderma Pigmentosum (XP). Studies on animal models are included as well. Clinical feature characteristics of each clinical subtype of XP are depicted according to the genotype, giving accurate and detailed information about the clinical features in terms of gene alterations, change of protein structure, and dysfunction in some of the repair pathways. This book is unique in that it provides detailed information on clinical features from more than 100 patients with XP-A, which is characterized by very severe manifestation of skin photosensitivity and neurological dysfunction. It will give readers important knowledge for understanding the concept and molecular mechanisms of DNA repair disorders. It also describes how to treat and care for patients with XP based on vast experience in clinical practice. DNA Repair Disorders will be a useful resource not only for physicians and basic scientists who are interested in and/or take care of patients with DNA repair disorders, but also dermatologists, neurologists, and researchers in the field of radiation biology and photobiology.

    Contents:
    1. Molecular mechanisms of DNA damage recognition for global genomic nucleotide excision repair: a defense system against UV-induced skin cancer
    2. Disorders with deficiency in TC-NER: molecular pathogenesis of Cockayne Syndrome and UV-sensitive syndrome
    3. Neurological symptoms of xeroderma pigmentosum
    4. Hearing impairment in xeroderma pigmentosum: animal models and human studies
    5. Epidemiological study of xeroderma pigmentosum in Japan: genotype-phenotype relationship
    6. Prenatal diagnosis of xeroderma pigmentosum
    7. Neurological disorders and chanllenging intervention in xeroderma pigmentosum and Cockayne syndrome
    8. Xeroderma pigmentosum in the UK
    9. Cockayne syndrome: clinical aspects
    10. Trichothiodystrophy
    11. Rothmund-Thomson syndrome
    12. Translesion DNA synthesis
    13. Ataxia-telangiectasia and Nijmegen breakage syndrome
    14. Management of xeroderma pigmentosum.
    Digital Access Springer 2018
  • Digital
    edited by Hisao Masai, Marco Foiani.
    Summary: This book reviews the latest trends and future directions of DNA replication research. The contents reflect upon the principles that have been established through the genetic and enzymatic studies of bacterial, viral, and cellular replication during the past decades. The book begins with a historical overview of the studies on eukaryotic DNA replication by Professor Thomas Kelly, a pioneer of the field. The following chapters include genome-wide studies of replication origins and initiation factor binding, as well as the timing of DNA replications, mechanisms of initiation, DNA chain elongation and termination of DNA replication, the structural basis of functions of protein complexes responsible for execution of DNA replication, cell cycle-dependent regulation of DNA replication, the nature of replication stress and cells? strategy to deal with the stress, and finally how all these phenomena are interconnected to genome instability and development of various diseases. By reviewing the existing concepts ranging from the old principles to the newest ideas, the book gives readers an opportunity to learn how the classical replication principles are now being modified and new concepts are being generated to explain how genome DNA replication is achieved with such high adaptability and plasticity. With the development of new methods including cryoelectron microscopy analyses of huge protein complexes, single molecular analyses of initiation and elongation of DNA replication, and total reconstitution of eukaryotic DNA replication with purified factors, the field is enjoying one of its most exciting moments, and this highly timely book conveys that excitement to all interested readers.

    Contents:
    Preface
    Biography
    Chapter1. Historical Perspective of Eukaryotic DNA Replication
    Chapter2. Regulation of replication origins
    Chapter3. Molecular mechanism for chromatin regulation during MCM loading in mammalian cells
    Chapter4. Initiation of DNA replication at the chromosomal origin of E. coli, oriC
    Chapter5. Initiation of DNA replication in the archaea
    Chapter6. Mechanism of lagging strand DNA replication in eukaryotes
    Chapter7. Functions of multiple clamp and clamp-loader complexes in eukaryotic DNA replication
    Chapter8. Termination of eukaryotic replication forks
    Chapter9. Structure of the MCM2-7 double hexamer and its implications for the mechanistic functions of the Mcm2-7 complex
    Chapter10. Architecture of The Saccharomyces cerevisiae Replisome
    Chapter11. Replication domains: genome compartmentalization into functional replication units
    Chapter12. Rif1-dependent regulation of genome replication in mammals
    Chapter13. G-quadruplexes and DNA replication origins
    Chapter14. Interaction of Rif1 protein with G-quadruplex in control of chromosome transactions
    Chapter15. Chromatin replication and histone dynamics
    Chapter16. The temporal regulation of S phase proteins during G1
    Chapter17. Roles of SUMO in replication initiation, progression, and termination
    Chapter18. The multiple roles of ubiquitylation in regulating challenged DNA replication
    Chapter19. Regulation of mammalian DNA replication via the ubiquitin-proteasome system
    Chapter20. Coordinating replication with transcription
    Chapter21. Fragility extraordinaire: Unsolved mysteries of chromosome fragile sites
    Chapter22. Cyclin E deregulation and genomic instability
    Chapter23. Replication through repetitive DNA elements and their role in human diseases.
    Digital Access Springer 2017
  • Digital
    edited by Brandt F. Eichman.
    Contents:
    Eukaryotic DNA replication with purified budding yeast proteins / Viktor Posse, Erik Johansson, and John F.X. Diffley
    Monitoring the replication of structured DNA through heritable epigenetic change / Guillaume Guilbaud and Julian E. Sale
    Visualizing replication fork encounters with DNA interstrand crosslinks / Ryan C. James, Marina A. Bellani, Jing Zhang, Jing Huang, Althaf Shaik, Durga Pokharel, Himabindu Gali, Julia Gichimu, Arun K. Thazhathveetil, and Michael M. Seidman
    Single-molecule imaging of replication fork conflicts at genomic DNA G4 structures in human cells / Wei Ting C. Lee, Dipika Gupta, and Eli Rothenberg
    Studying the DNA damage response in embryonic systems / Elena Lo Furno, Bénédicte Recolin, Siem van der Laan, Antoine Aze, and Domenico Maiorano
    Analysis of repair of replication-born double-strand breaks by sister chromatid recombination in yeast / Belén Gómez-González, Pedro Ortega, and Andrés Aguilera
    Determining the kinetics of break-induced replication (BIR) by the assay for monitoring BIR elongation rate (AMBER) / Liping Liu, Neal Sugawara, Anna Malkova, and James E. Haber
    Genomic mapping of DNA-repair reaction intermediates in living cells with engineered DNA structure-trap proteins / Jingjing Liu, Qian Mei, Sadeieh Nimer, Devon M. Fitzgerald, and Susan M. Rosenberg
    A mapping platform for mitotic crossover by single-cell multi-omics / Peter Chovanec and Yi Yin
    Characterization of DNA-PK-bound end fragments using GLASS-ChIP / Rajashree A. Deshpande and Tanya T. Paull
    Light activation and deactivation of Cas9 for DNA repair studies / Roger S. Zou and Taekjip Ha
    A detection method for the capture of genomic signatures : From disease diagnosis to genome editing / Orléna Benamozig, Lou Baudrier, and Pierre Billon
    A method to sequence genomic sites of mitotic DNA synthesis in mammalian cells / Jonathan Mailler, Laura Padayachy, and Thanos D. Halazonetis
    Loop-seq : A high-throughput technique to measure the mesoscale mechanical properties of DNA / Aakash Basu
    Characterization of the telomerase modulating activities of yeast DNA helicases / David G. Nickens and Matthew L. Bochman
    Single-molecule studies of yeast Rad51 paralogs / Upasana Roy, Youngho Kwon, Patrick Sung, and Eric C. Greene
    Synthesis and polymerase bypass studies of DNA-peptide and DNA-protein conjugates / Suresh S. Pujari and Natalia Tretyakova
    An efficient chemical screening method for structure-based inhibitors to nucleic acid enzymes targeting the DNA repair-replication interface and SARS CoV-2 / Davide Moiani, Todd M. Link, Chris A. Brosey, Panagiotis Katsonis, Oliver Lichtarge, Youngchang Kim, Andrzej Joachimiak, Zhijun Ma, In-Kwon Kim, Zamal Ahmed, Darin E. Jones, Susan E. Tsutakawa, and John A. Tainer.
    Digital Access ScienceDirect 2021
  • Digital
    edited by Jungsan Sohn.
    Contents:
    Intercellular communication in the innate immune system through the cGAS-STING pathway / Ramya Nandakumar, Samuel Joseph Windross, and Søren R. Paludan
    Analysis of human cGAS activity and structure / Wen Zhou, Aaron T. Whiteley, and Philip J. Kranzusch
    Chemical synthesis, purification, and characterization of 3′-5′-linked canonical cyclic dinucleotides (CDNs) / Changhao Wang, Min Hao, Qianqian Qi, Yashao Chen, and Jörg S. Hartig
    An SPR-based analysis of cGAS substrate KD and steady-state KM values / Erik C. Ralph and Justin Hall
    A pyrophosphatase-coupled assay to monitor the NTase activity of cGAS / Richard Hooy and Jungsan Sohn
    Tracking the polymerization of DNA sensors and inflammasomes using FRET / Zachary Mazanek and Jungsan Sohn
    Monitoring gasdermin pore formation in vitro / Shiyu Xia, Jianbin Ruan, and Hao Wu
    Measuring TREX1 and TREX2 exonuclease activities / Wayne O. Hemphill and Fred W. Perrino
    Kinetics of DNA-protein association and dissociation by stopped-flow spectroscopy / Johannes Rudolph and Karolin Luger
    Characterization of DNA bound cyclic GMP-AMP synthase using atomic force microscopy imaging / Alexander Lushnikov, Richard Hooy, Jungsan Sohn, and Alexey Krasnoslobodtsev
    Preparation of filamentous proteins for electron microscopy visualization and reconstruction / Mariusz Matyszewski and Jungsan Sohn
    Cryo-EM studies of NAIP-NLRC4 inflammasomes / Nicole Haloupek, Patricia Grob, Jeannette Tenthorey, Russell E. Vance, and Eva Nogales
    An integrative protocol for the structure determination of the mouse ASC-PYD filament / Adam Mazur, Petr Broz, and Sebastian Hiller
    Protein interactions of the inflammasome adapter ASC by solution NMR / Pedro Diaz-Parga and Eva de Alba
    Tracking DNA sensor and inflammasome complexes in cells using confocal microscopy / Brendan Antiochos
    Assessment of inflammasome and type I IFN responses to DNA viruses and DNA PAMPS / Guido Massaccesi and Michael A. Chattergoon
    Biochemical and microscopic analysis of inflammasome complex formation / Patrycja Swacha, Nelson O. Gekara, and Saskia F. Erttmann
    Comet and micronucleus assays for analyzing DNA damage and genome integrity / Hui Jiang, Swarupa Panda, and Nelson O. Gekara
    Workflows and considerations for investigating protein interactions of viral DNA sensors / Timothy R. Howard, Bokai Song, and Ileana M. Cristea
    TUBE and UbiCRest assays for elucidating polyubiquitin modifications in protein complexes / Swarupa Panda, Hui Jiang, and Nelson O. Gekara.
    Digital Access ScienceDirect 2019
  • Digital
    Hiromi Nishida, Taku Oshima, editors.
    Summary: This book comprehensively discusses our current understanding of the role and biological mechanisms of horizontal transfer of genetic elements in the environment, which has been important in the evolution of prokaryotes (archaea and bacteria). Horizontal transfer of genetic elements generates variations of prokaryotes and their genomes. Comparative studies of genomes revealed that it frequently occurred during archaeal and bacterial evolution. The book introduces a variety of studies related to horizontal gene transfer, gene silencing, plasmids, phages, transposons, and the emergence of microbes that degrade man-made xenobiotics and have antimicrobial resistance. Written by leading researchers in DNA traffic, the book is a valuable guide to horizontal transfer for both young scientists and experts in the field. -- Provided by publisher.

    Contents:
    Functions of Archaeal Nucleoid Proteins: Archaeal Silencers are Still Missing / Maruyama, Hugo (et al.)
    Acquired and Innate Immunity in Prokaryotes Define Their Evolutionary Story / Ito, Toshihiro (et al.)
    RNA-Mediated Crosstalk Between Bacterial Core Genome and Foreign Genetic Elements / Miyakoshi, Masatoshi
    Bacteria-Virus Interactions / Yoshida, Takashi (et al.)
    Plasmids and Their Hosts / Shintani, Masaki (et al.)
    Overlooked Broad-Host-Range Vector Particles in the Environment / Chiura, Hiroshi X.
    Bacterial Transposable Elements and IS-Excision Enhancer (IEE) / Kusumoto, Masahiro (et al.)
    Mobile Genetic Elements Involved in the Evolution of Bacteria that Degrade Recalcitrant Xenobiotic Compounds / Nagata, Yuji (et al.)
    DNA Traffic in the Environment and Antimicrobial Resistance / Hooton, Steven P. (et al.)
    Digital Access Springer 2019
  • Digital
    edited by Monica Rinaldi, Daniela Fioretti, Sandra Iurescia.
    Contents:
    Blueprint for DNA vaccine design / Sandra Iurescia, Daniela Fioretti, and Monica Rinaldi
    Enhancement of plasmid-mediated transgene expression / Daniela Fioretti, Sandra Iurescia, and Monica Rinaldi
    Strategies for improving DNA vaccine performance/ Sandra Iurescia, Daniela Fioretti, and Monica Rinaldi
    Enhancement of DNA vaccine efficacy by intracellular targeting strategies / Elisabete Borges Freitas ... [et al.]
    Progresses in DNA-based heterologous prime-boost immunization strategies / Ronald J. Jackson, David B. Boyle, and Charani Ranasinghe
    Development of antibiotic-free selection system for safer DNA vaccination / Jeremy M. Luke, Aaron E. Carnes, and James A. Williams
    Electroporation-based DNA delivery technology : methods for gene electrotransfer to skin / Anita Gothelf and Julie Gehl
    DNA vaccination in skin enhanced by electroporation / Kate E. Broderick, Amir S. Khan, and Niranjan Y. Sardesai
    Intradermal vaccination by DNA tattooing / Joost H. van den Berg ... [et al.]
    Microneedle applications for DNA vaccine delivery to the skin / Hae-yong Seok ... [et al.]
    Multivalent DNA-based vectors for DNA vaccine delivery / Young Hoon Roh ... [et al.]
    Superparamagnetic nanoparticle delivery of DNA vaccine / Fatin Nawwab Al-Deen ... [et al.]
    Plasmid fermentation process for DNA immunization applications / Aaron E. Carnes and James A. Williams
    Pharmaceutical grade large-scale plasmid DNA manufacturing process / Marco Schmeer and Martin Schleef
    Protective and therapeutic DNA vaccination against allergic diseases / Almedina Isakovic ... [et al.]
    Immunotherapy for Alzheimer's disease : DNA- and protein-based epitope vaccines / Hayk Davtyan, Irina Petrushina, and Anahit Ghochikyan
    Tetravalent DNA vaccine product as a vaccine candidate against Dengue / Kevin R. Porter, Nimfa Teneza-Mora, and Kanakatte Raviprakash
    DNA vaccination as a treatment for chronic kidney disease / Yuan Min Wang and Stephen I. Alexander.
    Digital Access Springer 2014
  • Digital
    Katherine Moran, Rosanne Burson, Dianne Conrad.
    Summary: "The Doctor of Nursing Practice Project: A Framework for Success, Third Edition provides the foundation for the scholarly process enabling DNP students to work through their project in a more effective, efficient manner. The Third Edition is intended for practical application and remains focused on the scholarly project. In addition, it specifically outlines how the project has been used to prepare clinical scholars for practice, a focus seen nationally. A new chapter on health policy highlights the DNP core competencies that are used to advocate for healthcare policy change. This chapter covers how policy impacts practice, how the DNP nurse is the leader of the profession, their role as it relates to advocacy, the connection of the DNP project and health policy and concludes with an action plan. Coverage of the scholarly project tools and exemplars which highlight the variety of work by DNP nurses are also found throughout the text. Key Features Updated historical perspectives Overview of project variability Coverage of project sustainability and measures of impact New chapter on health policy Navigate 2 Essentials Package which will feature digital versions of the project tools"--Provided by publisher.

    Contents:
    Machine generated contents note: Section I The Doctor of Nursing Practice Degree Chapter 1 Setting the Stage for the doctor of Nursing Practice Project Chapter 2 Defining the Doctor of Nursing Practice: Current Trends Chapter 3 Scholarship in Practice Chapter 4 Health Care Policy and Advocacy Section II The DNP Project Chapter 5 The Phenomenon of Interest Chapter 6 Developing the DNP Project Chapter 7 Aligning Design, Method, and Evaluation with the Clinical Question Chapter 8 Interprofessional and Intraprofessional Collaboration in the DNP Project Chapter 9 The DNP Project Team Chapter 10 Creating and Developing the Project Plan Chapter 11 Driving the Practicum to Impact the DNP Project Chapter 12 The Proposal Chapter 13 The DNP Project Toolbox Chapter 14 Project Implementation Section III Doctor of Nursing Practice Outcomes Chapter 15 Disseminating the Results Chapter 16 The Rest of the Story
    Evaluating the Doctor of Nursing Practice.
    Digital Access R2Library 2020
    Limited to 1 simultaneous user
  • Digital
    [edited by] Katherine J Moran, Rosanne Burson, Dianne Conrad.
    Summary: "The Doctor of Nursing Practice Project : A Framework for Success, Fourth Edition guides students and faculty in the DNP project process. With a primary focus on delivering key information on planning, implementing, and evaluating a project, the text also emphasizes the impact that DNP-prepared nurses and well-developed DNP projects have in shaping the future of nursing"-- Provided by publisher.

    Contents:
    Setting the Stage for the Doctor of Nursing Practice Project
    Defining the Doctor of Nursing Practice : Historical and Current Trends
    Scholarship in Practice
    Population Health and Health Care Policy
    The Phenomenon of Interest : Leading to Problem Identification
    Validating the Problem and Conceptualizing the Project Plan
    Aligning Design, Method, and Evaluation with the Clinical Question
    The DNP Project Team : Preparing for Project Implementation
    The Proposal
    Leading Implementation Through Collaboration
    Driving the Practicum to Attain Competency and Leverage Impact through the DNP Project
    Evaluating the Doctor of Nursing Practice Project From Data to Knowledge : Disseminating the Results
    The Value and Impact of Practice Doctorate Scholarship.
    Digital Access R2Library 2024
    Limited to 1 simultaneous user
  • Digital
    Janice P. Nimura.
    Summary: Elizabeth Blackwell believed from an early age that she was destined for a mission beyond the scope of "ordinary" womanhood. Though the world at first recoiled at the notion of a woman studying medicine, her intelligence and intensity ultimately won her the acceptance of the male medical establishment. In 1849, she became the first woman in America to receive an M.D. She was soon joined in her iconic achievement by her younger sister, Emily, who was actually the more brilliant physician. Exploring the sisters' allies, enemies, and enduring partnership, Janice P. Nimura presents a story of trial and triumph. Together, the Blackwells founded the New York Infirmary for Indigent Women and Children, the first hospital staffed entirely by women. Both sisters were tenacious and visionary, but their convictions did not always align with the emergence of women's rights - or with each other. From Bristol, Paris, and Edinburgh to the rising cities of antebellum America, this richly researched new biography celebrates two complicated pioneers who exploded the limits of possibility for women medicine. As Elizabeth herself predicted, "a hundred years hence, women will not be what they are now"--From dust jacket.

    Contents:
    Prologue
    Bristol
    New York
    Cincinnati
    Betweenity
    Admission
    Blockley almshouse
    Diploma
    Paris
    Setback
    London
    Practice
    Admission, again
    Edinburgh
    New faces
    Infirmary
    Recognition
    War
    College
    Divergence
    Coda.
    Digital Access 2021
    Limited to 1 simultaneous userSUNet ID login required
  • Print
    Greta Jones.
    Summary: "This is the first full-length study of doctor migration from Ireland covering roughly a century of the export of Irish medical graduates to other parts of the world. From 1860 around forty percent of Ireland's medical graduates left to pursue careers elsewhere. The book examines the factors which drove emigration, the shifting destinations of the emigrants and the effect of migration both upon them and the Ireland they left behind. This was the migration of a part of the Irish middle class, small in terms of Irish emigration as a whole, but important in the global history of medical migration. At the end of the twentieth century doctor migration as a whole has increased and become a significant part of the medical experience. The book is a contribution to the growing literature on the global history of doctor movements across the world"-- Provided by publisher.
  • Print
    edited by David K.C. Cooper.
    Summary: The medical profession is rich in those who have made names for themselves outside of medicine. The fields of literature, exploration, business, sport, entertainment, and beyond abound with doctors whose interests lie outside medicine. This book, largely written by members of the medical profession, examines the efforts of doctors in non-medical fields. The doctors discussed here are those who are, or were, well-known to the public for their contributions to their non-medical fields of choice. In many cases, the public may have been unaware that a subject was medically qualified. This book provides wide-ranging and comprehensive biographical sketches of forty-two doctors who are best known to the public for their contributions to fields outside of medicine.--Back cover.
    Print Access Request
    Location
    Version
    Call Number
    Items
    Books: History - LC Classification (Downstairs)
    R134 .D63 2014
    1
  • Print
    Contents:
    v. 1. Chemical substances A-D
    v. 2. Chemical substances E-O
    v. 3. Chemical substances P-Z
    v. 4. Biological exposure indices
    v. 5. Physical agents.
    Print
    Location
    Version
    Call Number
    Items
    Reference (Upstairs)
    RA1229 .D626 2001
    9
  • Digital
    Christina Strube, Heinz Mehlhorn, editors.
    Summary: This book presents the latest information on canine parasites with zoonotic potential, to help avoid human infections. Compiled by international specialists, it covers protozoa, ectoparasites and helminth species of clinical importance in dogs, as well as the state of the art in diagnosis, preventive measures and potentially necessary treatment schemes. Dogs are commonly kept in families around the world and can predispose their human companions to disease. Updating and deepening insights from other specialist literature, the book is intended for practitioners and scientists alike. It also offers practical guidance for veterinary and human physicians and highlights unexplored research areas, making it a valuable resource for students and educated non-experts with an interest in parasitology, infectiology and zoonotic pet diseases.

    Contents:
    Chapter 1: Introduction
    Chapter 2: The zoonotic dog roundworm Toxocaracanis, a worldwide burden of public health
    Chapter 3: Canine leishmaniasis
    Chapter 4: The Challenges with Canine Giardia
    Chapter 5: Dogs and their role in the eco-epidemiology of Chagas disease
    Chapter 6: Echinococcus species - tiny tapeworms
    Chapter 7: An update on the status of hydatidosis/echinococcosis in domestic animals, wildlife and humans in Australia
    Chapter 8: Dipylidiumcaninum
    Chapter 9: Ancylostoma caninum and other canine hookworms
    Chapter 10: Strongyloidiasis
    really a zoonosis?
    Chapter 11: Dirofilaria spp. Do they get under your skin (or into your heart)?
    Chapter 12: Guinea worm infection in dogs: a case of reverse zoonosis that impedes Dracunculusmedinensiseradication
    Chapter 13: Ticks, dogs and humans - an endangered community
    Chapter 14: Trematodes attacking dogs and humans.
    Digital Access Springer 2021
  • Print
    Philip C. Hébert.
    Summary: "The third edition of Doing Right: A Practical Guide to Ethics for Medical Trainees and Physicians is a practical guide to analyzing and resolving the ethical dilemmas medical practitioners face on a day-to-day basis. Drawing extensively on real-life scenarios, this book takes a case-based approach to provide students and practitioners with the advice and skills they need to help their patients and overcome ethical challenges in the field. Fully revised to include up-to-date coverage of such important topics as patient-practitioner relationships in the digital age and advances in reproductive medicine and reproductive technologies, this third edition of Doing Right will provide readers with the most up-to-date guidebook to medical ethics available."--Publisher's website.

    Contents:
    Ethics matters : doing ethically sound medicine
    The almost revolution : autonomy and patient-based care
    No man an island : confidentiality and trust
    The power to heal : truth and deception in clinical practice
    The power to choose : due care and informed consent
    The waning and waxing self : capacity and incapacity in medical care
    Helping and not harming : beneficence and non-maleficence
    Conduct becoming : medical professionalism and managing error
    Beyond the patient : doing justice to justice
    Labour pains : ethics and new life
    A dark wood : end-of-life decisions
    Questions of culture, genetics, and science.
    Print Access Request
    Location
    Version
    Call Number
    Items
    Books: General Collection (Downstairs)
    R724 .H39 2014
    1
  • Digital
    Meerambika Mahapatro.
    Summary: This book discusses health care issues related to domestic violence, using extensive case studies from India. By discussing the global literature, legal systems, methodological challenges of gathering information on domestic violence, and health systems issues, along with learnings from case studies, it fills a significant gap in the literature between health care policy and practice vis-à-vis victims of domestic violence. It therefore enables a systemic and systematic response to incidents of domestic violence. Policy instructions, court verdicts, government interventions, community-based direct interventions and related case discussions in the book help in the understanding and management of cases. Though the book uses case studies from India, it addresses globally relevant issues for health care professionals. In view of the paucity of application of systematic evidence-based knowledge, the holistic perspective presented in the book is important to prevent domestic violence, protect women's rights, and promote healthcare and wellbeing of women and children facing domestic violence. Medical professionals are expected to intervene in instances of injuries related to domestic violence--a responsibility that they are currently unable to fulfill due to lack of training in recognizing abuse and lack of tools for intervention. This book improves hands-on-knowledge by providing information on where to refer victims for assistance and timely intervention. Comprehensive yet lucid, this book is useful for academics, policy makers, non-government organizations and women's rights groups in helping victims during and after a violent episode and also in improving reporting and referral services.
    Digital Access Springer 2018
  • Print
    Parveen Ali, Julie McGarry, editors.
    Summary: This book is taking a broad health focused approach towards Domestic Violence and Abuse (DVA). It is now well established that DVA exerts a significant and detrimental impact on the health and wellbeing of those who experience abuse. Universally healthcare professionals encounter individuals and families where DVA is or has taken place. This book is beneficial to a range of health care professionals through an exploration of theories and classifications of DVA, consideration of DVA in different contexts and consideration of the core issues surrounding working with individuals and families where DVAhas been identified. It provides a much needed evidence based addition to the existing texts in this field in terms of the inclusion of real life scenarios, reflective exercises and pointers for further practice development. This book is a key point of reference for professionals working within a broad range of health care environments.

    Contents:
    Foreword
    About the authors
    Acknowledgments
    1. DVA/IPV understanding and setting the context for the book (set out the DVA occurs everywhere in healthcare settings)
    2. Why is DVA/IPV a health issue? ? global and UK policy context
    3. The impact of DVA/IPV on health ? explore long/short term physical and mental health. The concept of health as multi-faceted
    4. Clinical settings where DVA/IPV may be encountered
    5. The response of healthcare professionals to DVA/IPV ? barriers and opportunities to effective identification and management (perhaps include the screening debate)
    6. DVA and hard to reach groups
    7. DVA and children
    8. DVA and older populations
    9. Working with other agencies
    10. Reflection and future learning .
    Digital Access Springer 2020
  • Print
    edited by Kristopher P. Croome, Paolo Muiesan, C. Burcin Taner.
    Summary: This book presents the first comprehensive review of all facets of liver transplantation using DCD donors. Each of the 19 chapters are written by leading experts in the field, representing some of the most experienced DCD liver transplant programs in the world. Several topics have overlapping coverage in different chapters, providing the reader with the perspective of multiple experts on crucial topics. Chapters also highlight the steps towards building a DCD liver transplant program, the importance of donor and recipient selection, as well as state-of-the-art developments and future directions in the utilization of these organs. Donation after Circulatory Death (DCD) Liver Transplantation serves as a valuable resource for all those involved in liver transplantation using DCD donors.

    Contents:
    The History of DCD Liver Transplant
    Ethics and Law of DCD Transplant
    Donor Procurement Operation in Donation after Circulatory Death Donors
    Predicting the likelihood a DCD donor will expire
    Warm Ischemia time
    Ischemia Reperfusion Injury and therapeutic strategy in Donation after Circulatory Death (DCD) liver transplantation
    Donor Selection in DCD liver transplantation
    Thrombolytic Therapy in Liver Transplantation Using Grafts from Donation After Circulatory Death Donors
    Recipient Selection in DCD-Liver Transplantation
    Outcomes in DCD liver transplantation
    Non-biliary Complications Associated with liver grafts from Donation After circulatory Death donors
    Ischemic Cholangiopathy
    Hypothermic machine perfusion in liver transplantation using grafts from donation after circulatory death donors
    Normothermic Regional Perfusion
    Ex Vivo Normothermic Machine Perfusion
    Liver Transplantation From Uncontrolled DCD Donors
    Developing a DCD Liver Transplant Program
    Anesthesia for DCD Liver Transplantation
    DCD Liver Transplant: The OPO Perspective.
    Digital Access Springer 2020
  • Digital
    edited by Marco Diana, Gaetano Di Chiara and Pier Franco Spano.
    Summary: Progress in Brain Research is a well-established international series examining major areas of basic and clinical research within neuroscience, as well as emerging and promising subfields. This volume, concentrates on state-of-the-art of dopamine research: from basic science to clinical applications. It covers topics including thalamostriatal synapses as a substrate for dopamine action; the multilingual nature of dopamine neurons; ethanol-mechanisms along the mesolimbic dopamine system, and much more. Progress in Brain Research is the most acclaimed and accomplished series in neuroscience, firmly established as an extensive documentation of the advances in contemporary brain research. The volumes, some of which are derived from important international symposia, contain authoritative reviews and original articles by invited specialists. The rigorous editing of the volumes assures that they will appeal to all laboratory and clinical brain research workers in the various disciplines: neuroanatomy, neurophysiology, neuropharmacology, neuroendocrinology, neuropathology, basic neurology, biological psychiatry, and the behavioral sciences.The most acclaimed and accomplished series in neuroscienceThis volume looks at dopamine researchin the light of the newest scholarly discoveries and insights.
    Digital Access ScienceDirect 2014
  • Digital
    Jin-Xia Zhu, editor.
    Summary: Dopamine is widely present in the central and peripheral nervous systems, as well as in non-nervous systems. Parkinson's disease is well recognized as a dopaminergic neurodegenerative disorder, and affected patients often show early signs of gastrointestinal disorders at initial stages of the disease. Apart from the changes that occur in emotion, movement behaviors, learning and memory, metabolism etc., dopamine has also been demonstrated to play very crucial roles in the functional regulation of peripheral organs such as the heart, blood vessels, kidneys, and gut. Most recently, dopamine function in the gut has received enormous attention. Not only does dopamine regulate gut motility, ion transport, and mucosal barrier, but it is becoming more pertinent that more than 60% of dopamine in the body stems from the gut, which has not yet been properly addressed and substantially explored. Therefore, this book will discuss the brain-gut axis by providing novel and significant insight into the essence of gut-derived dopamine in mammals. It aims to inspire further research on dopaminergic regulation of gut function and disease genesis.

    Contents:
    1 Introduction
    2 Synthesis and Metabolism of Gut Dopamine
    3 Dopamine Receptors in the Gastrointestinal Tract
    4 Dopamine and Gastrointestinal Mucosa Function
    5 Dopamine and Gastrointestinal Mobility
    6 Dopamine in the Pancreas.
    Digital Access Springer 2021
  • Print
    Anna Lembke, M.D.
    Summary: We are living in a time of unprecedented access to high-reward, high-dopamine stimuli: drugs, food, news, gambling, shopping, gaming, texting, sexting. The smartphone is the modern-day hypodermic needle, delivering digital dopamine 24/7 for a wired generation. Lembke explores new scientific discoveries that explain why the relentless pursuit of pleasure leads to pain-- and what to do about it. She illustrates how finding contentment and connectedness means keeping dopamine in check. The secret to finding balance is combining the science of desire with the wisdom of recovery. -- adapted from jacket

    Contents:
    Introduction: The problem
    The pursuit of pleasure. Our masturbation machines ; Running from pain ; The pleasure-pain balance
    Self-binding. Dopamine fasting ; Science, time, and meaning ; A broken balance?
    The pursuit of pain. Pressing on the pain side ; Radical honesty ; Prosocial shame
    Conclusion: Lessons of the balance.
    Print
    Location
    Version
    Call Number
    Items
    Books: General Collection (Downstairs)
    BF515 .L46 2021
    1
  • Digital
    edited by Mario Tiberi.
    Contents:
    Genetic and epigenetic methods for analysis of the dopamine D2 receptor gene / Laura M. Fiori , Mireille Daigle , and Paul R. Albert
    Characterization of D1 dopamine receptor posttranscriptional regulation / Eldo V. Kuzhikandathil
    Computational approaches in the structure-function studies of dopamine receptors / Mayako Michino and Lei Shi
    Cell-free protein synthesis and purification of the dopamine D2 receptor / Dipannita Basu ... [et al.]
    Wnt ligand binding to and regulation of dopamine D2 receptors / Sehyoun Yoon , Mi-Hyun Choi , and Ja-Hyun Baik
    Regulation of pre- and postsynaptic protein phosphorylation by dopamine D2 receptors / Alessandra Bonito-Oliva, Giada Spigolon, and Gilberto Fisone
    Study of dopamine D1 receptor regulation by G protein-coupled receptor kinases using whole-cell phosphorylation and cross-linking methods / Keyvan Sedaghat ... [et al.]
    Ubiquitination of dopamine receptor studied by sequential double immunoprecipitation / Kamila Skieterska, Pieter Rondou, and Kathleen Van Craenenbroeck
    Dopamine receptors in the subthalamic nucleus : identification and localization of D5 receptors / Lionel Froux ... [et al.]
    MALDI mass spectrometry imaging of dopamine and PET D1 and D2 receptor ligands in rodent brain tissues / Richard J. A. Goodwin, Mohammadreza Shariatgorji, and Per E. Andren
    Positron emission tomography imaging of dopaminergic receptors in rats / Boguslaw Szczupak and Abraham Martín
    Transactivation of receptor tyrosine kinases by dopamine receptors / Jeff S. Kruk ... [et al.]
    Dopamine receptors in human embryonic stem cell differentiation / Glenn S. Belinsky ... [et al.]
    Calcium and phospholipase Cβ signaling through dopamine receptors / Lani S. Chun, R. Benjamin Free, and David R. Sibley
    Intracellular trafficking assays for dopamine D2-like receptors / Chengchun Min, Mei Zheng, and Kyeong-Man Kim
    Study of crosstalk between dopamine receptors and ion channels / Ping Su, Albert H. C. Wong, and Fang Liu
    Study of dopamine receptor and dopamine transporter networks in mice / Victor Gorgievski, Eleni T. Tzavara, and Bruno Giros
    Optogenetic regulation of dopamine receptor-expressing neurons / T. Chase Francis and Mary Kay Lobo
    Characterization of D3 dopamine receptor agonist-dependent tolerance property / Samantha R. Cote and Eldo V. Kuzhikandathil
    Dopamine D1 and D2 receptors in chronic mild stress : analysis of dynamic receptor changes in an animal model of depression using in situ hybridization and autoradiography / Dariusz Zurawek ... [et al.].
    Digital Access Springer 2015
  • Digital
    Michael Hofbeck, Karl-Heinz Deeg, Thomas Rupprecht.
    Contents:
    1. The normal examination
    2. Atrial septal defects
    3. Ventricular septal defect
    4. Atrioventricular septal defect
    5. Patent ductus arteriosus
    6. Aortopulmonary window
    7. Pulmonary stenosis
    8. Pulmonary atresia with intact ventricular septum (PAiVS)
    9. Tricuspid atresia
    10. Ebsteins anomaly
    11. Tetralogy of Fallot
    12. Pulmonary atresia and ventricular septal defect
    13. Truncus arteriosus
    14. Double outlet right ventricle
    15. Transposition of the great arteries
    16. Functionally univentricular heart
    17. Anomalous pulmonary venous connections
    18. Anomalies of left ventricular inflow and mitral valve
    19. Aortic stenosis, regurgitation and anomalies of the left ventricular outflow tract
    20. Hypoplastic left heart syndrome
    21. Coarctation of the aorta
    22. Interruption of the aortic arch
    23. Vascular rings and anomalies of the aortic arch vessels
    24. Echocardiographic differential diagnosis of cyanotic infants
    25. Echocardiography for the neonatologist.
    Digital Access Springer 2017
  • Digital
    Karl-Heinz Deeg, Thomas Rupprecht, Michael Hofbeck ; with contributions by Doris Franke, Michael Riccabona, Heiko Dudwiesus.
    Summary: This book covers the full range of current applications of Doppler sonography in infancy and childhood, describing the variety of potential findings with the aid of a wealth of images. After an introductory chapter on the physical and technical basis of Doppler sonography, applications of cerebral Doppler sonography in infancy and of transcranial Doppler sonography in childhood are addressed, with numerous examples of imaging appearances. The major part of the book is devoted to Doppler sonography of the brain, face and neck and of the abdomen, covering normal abdominal vessels, liver, spleen, pancreas, and mesenteric and renal circulation. Imaging of the ovaries and testes is also presented, encompassing the differential diagnosis of acute scrotum and other space-occupying lesions of the testis. The book closes by considering Doppler sonography of soft tissue and vascular malformations, and the influence of congenital heart malformations on flow parameters in peripheral arteries. Doppler Sonography in Infancy and Childhood will be an invaluable reference for pediatricians, neonatologists, pediatric sonographers, and pediatric and general radiologists.

    Contents:
    Physical and technicalbasics of Doppler sonography
    Cerebral Doppler sonography in infancy
    Transcranial cerebral Doppler sonography in childhood
    Dopplersonography of the thyroid and of the soft tissue of face and neck
    Doppler sonography of normal abdominal vessels
    Doppler sonography of the liver
    Doppler sonography of the spleen
    Doppler sonography of the pancreas
    Doppler sonography of the mesenteric circulation and bowel
    Renal Doppler sonography
    Dopplersonography of the adrenal gland
    Doppler sonography of the testes
    Doppler sonography of the ovaries
    Doppler sonography of soft tissue and vascular malformations
    Influence of congenital heart malformations on flow parameters in peripheral arteries.
    Digital Access Springer 2015
  • Digital
    Bogdan Czerniak.
    Contents:
    General considerations
    Clinical considerations and imaging of bone tumors / Colleen M. Costelloe and John E. Madewell
    Molecular biology of bone tumors
    Benign osteoblastic tumors
    Osteosarcoma
    Benign cartilage lesions
    Malignant cartilage tumors
    Fibroosseous lesions
    Fibrous and fibrohistiocytic lesions
    Giant-cell lesions
    Ewing's sarcoma and related entities
    Hematopoietic tumors / April Ewton
    Vascular lesions
    Neurogenous tumors and neurofibromatosis affecting bone / Gregory N. Fuller
    Cystic lesions
    Miscellaneous mesenchymal tumors
    Adamantinoma of long bone
    Chordoma and related lesions
    Metastic tumors in bone / John D. Reith
    Synovial lesions
    Sclerosing bone lesions
    Tumor-induced osteomalacia and rickets
    Reactive and metabolic conditions simulating neoplasms of bone
    Precancerous conditions.
    Digital Access ClinicalKey 2016
  • Digital
    Jablonski, Stanley.
    Digital Access
    Provider
    Version
    ClinicalKey Nursing
    ClinicalKey
  • Print
    Dorland, W. A. Newman.
    Print Access
    Location
    Version
    Call Number
    Items
    Reference (Upstairs)
    R121 .D73
    2
    Retired Reference (Downstairs)
    R121 .D73
    9
  • Digital
    Victor R. Alekseev, Bernadette Pinel-Alloul, editors.
    Summary: This is the second volume on dormancy in aquatic organisms. The book is divided into three parts whereby the first part is devoted to several groups of aquatic organisms which are under-studied in terms of the dormancys role in the life cycle. The second part looks at the use of dormancy phenomena in science and potential human applications. Furthermore, part 3 comprises of examples of using modeling in relation to dormancy phenomenon and it opens with a theoretical analysis of studies of biological information, including seasonal information. This work can be used as a text book for students as well as a manual for science and practice purposes in ecology, aquaculture, nature protection and space researches with regards to creating ecological life supporting systems and discovering extraterrestrial life on other planets with harsh environmental conditions.

    Contents:
    PART I: Strategies and mechanisms of diapause in aquatic invertebrates
    1. Professor Oscar Ravera: long life in science
    2. Introduction to dormancy in aquatic invertebrates: mechanism of induction and termination, hormonal and molecular-genetic basis
    3. Dormancy in freshwater tardigrades
    4. Fish: diapause, dormancy, aestivation, and delay in gonad development
    5. Cysts and resting eggs from marine zooplankton. Dimension of the phenomenon, physiology of rest, ecological and biogeographic implications
    PART II: The role of diapause in science and human uses
    6. Studying on dormancy in space conditions
    7. Resistance of dormant eggs of cladocera to anthropogenic pollutants
    8. Mechanisms facilitating dispersal of dormant eggs in a planktonic crustacean
    9. Seasonal diphenism in daphnia from temperate environments: Organismal traits and molecular regulation
    10. The role of chemical interactions in embryonic diapause induction in zooplankton
    11. Aquatic invertebrate dormancy and medicine
    PART III: Dormancy, biological information and modelling
    12. Biological information and dormancy in aquatic population modeling
    13. Biological information, dormancy and individual based modeling of daphnia population dynamics
    14. The role of biotic and abiotic interactions in summer diapause in cyclopoids: Conceptual model and field validation in southern Quebec boreal lakes
    15. The model of dynamics of population number of the plankton
    16. Use of simulation to analyze parasite impacts on Volga delta Brachionus calyciflorus pallas rotifer dynamics: Abundance, reproduction and transition to diapause.
    Digital Access Springer 2019
  • Digital
    John Scott Baird.
    Summary: This book chronicles the life and accomplishments of Dorothy Hansine Andersen, a pioneering American pathologist and pediatrician who was the first person to define, diagnose, and treat cystic fibrosis. Divided into three parts, the book begins by detailing Anderson's early life, including being orphaned as an adolescent, her college career, and her laborious start in the medical field. Part II then examines Andersen's role in defining the new disease cystic fibrosis of the pancreas and her career of active engagement in various clinical pursuits and research, both in pathology and pediatrics. Chapters in this section also discuss the numerous attempts made by others to minimize Andersen's work through gender bias and the Matilda Effect. The book concludes by reviewing the foundations laid for CF, Andersen's legacy, and her terminal illness. Featuring an engaging narrative style, Dorothy Hansine Andersen is a historically relevant, invaluable text for anyone interested in the life of Dorothy Anderson and the nascence of cystic fibrosis diagnoses.

    Contents:
    Part I: Life before Babies Hospital
    Chapter 1: A beginning
    Chapter 2: Orphaned
    Chapter 3: College and medical school
    Chapter 4: False start
    Chapter 5: A reboot
    Part II: Babies Hospital during the McIntosh Era
    Chapter 6: Historical perspectives
    Chapter 7: Synergy
    Chapter 8: Andy's abandoned farm
    Chapter 9: Scoring the first goal
    Chapter 10: CF firsts
    Chapter 11: To Dr. Andersen who has pulled me through many a tough year
    Chapter 12: McIntosh, pediatric pathology, and Columbia University.-Chapter 13: CF sweat and the Matilda Effect
    Chapter 14: Glycogen storage diseases
    Chapter 15: Celiac disease
    Chapter 16: Randomized, controlled trials
    Chapter 17: Babies Hospital siblings
    Chapter 18: A last decade of CF research
    Chapter 19: Pediatric heart diseases
    Part III: Beyond Babies Hospital and the McIntosh Era
    Chapter 20: Time to enjoy the view
    Chapter 21: A foundation and a club for CF
    Chapter 22: The end of an era
    Chapter 23: Cancer.
    Digital Access Springer 2022
  • Digital
    clinical editor, Margaret Harvey, PhD, MSN, MAT, CNE, Chamberlain College of Nursing, Indianapolis Campus President.
    Summary: Calculate correct dosages with safety and confidence, with the easy-to-follow nursing expertise of Dosage Calculations Made Incredibly Easy! 5th edition. This fully illustrated guide offers the complete how-to on calculating dosages for all drug forms and administration routes, with numerous practice exercises and seasoned guidance on interpreting drug orders accurately. Understand class materials more fully, get ready for the NCLEX or certification exam, or refresh your calculation skills with this enjoyable text.

    Contents:
    Fractions / Carol Lee Cherry
    Decimals and percentages / MaryAnn Edelman
    Ratios, fractions, proportions, and solving for X / Carol Lee Cherry
    Dimensional analysis / MaryAnn Edelman
    Metric system / Lisa Benson
    Alternative measurement systems / Lisa Benson
    Drug orders / Donna Blair
    Administration records / Donna Blair
    Preventing drug errors / Nancy J. Cichra
    Calculating oral drug dosages / Nancy J. Cichra
    Calculating topical and rectal drug dosages / Jacqueline Sue Inman
    Calculating parenteral injections / Jacqueline Sue Inman
    Calculating IV infusions / DeLaina A. McCane
    Calculating pediatric dosages / Sarah Wallace
    Calculating obstetric drug dosages / Cheryl L. DeGraw
    Calculating critical care dosages / DeLaina A. McCane.
    Digital Access Ovid 2016
  • Digital
    edited by Rakesh K. Tekade.
    Summary: Dosage Form Design Parameters, Volume II, examines the history and current state of the field within the pharmaceutical sciences, presenting key developments. Content includes drug development issues, the scale up of formulations, regulatory issues, intellectual property, solid state properties and polymorphism. Written by experts in the field, this volume in the Advances in Pharmaceutical Product Development and Research series deepens our understanding of dosage form design parameters. Chapters delve into a particular aspect of this fundamental field, covering principles, methodologies and the technologies employed by pharmaceutical scientists. In addition, the book contains a comprehensive examination suitable for researchers and advanced students working in pharmaceuticals, cosmetics, biotechnology and related industries.

    Contents:
    Front-matter
    Copyright
    Dedication
    List of Contributors
    About the Editor
    Levels of Solid State Properties: Role of Different Levels During Pharmaceutical Product Development
    Basics of Crystallization Process Applied in Drug Exploration
    Role of Amorphous State in Drug Delivery
    Particulate Level Properties and its Implications on Product Performance and Processing
    Bulk Level Properties and its Role in Formulation Development and Processing
    Concepts of Hypothesis Testing and Types of Errors
    Experimental Design and Analysis of Variance
    Basic Concept and Application of Sampling Procedures
    Statistical Techniques in Pharmaceutical Product Development
    Drug–Excipient Interaction and Incompatibilities
    Documentation Protocol in Product Development Including Clinical Records
    Correlation Between In Vitro and In Vivo Screens: Special Emphasis on High Throughput Screening and High Throughput Pharmacokinetic Analysis
    Sterilization of Pharmaceuticals: Technology, Equipment, and Validation
    Package Development of Pharmaceutical Products: Aspects of Packaging Materials Used for Pharmaceutical Products
    Package Types for Different Dosage Forms
    Food and Drug Laws Affecting Pharmaceutical Product Design, Development, and Commercial Manufacturing
    Guiding Principles for Human and Animal Research During Pharmaceutical Product Development
    Applications of Computers in Pharmaceutical Product Formulation
    Patents and Other Intellectual Property Rights in Drug Delivery
    Computer-Aided Prediction of Pharmacokinetic (ADMET) Properties
    Ethics and Legal Protection of Uses of Computer Applications in Pharmaceutical Research
    Index
    Digital Access ScienceDirect 2018
  • Digital
    A-Yong Yu, editor.
    Summary: This book introduces the principle, main parameters, acquisition mode and operation procedure of Optical Quality Analysis System II (OQAS II) based on double-pass technology. OQAS II is increasingly used in the diagnosis and assessment of ocular diseases, especially for cataract. In this book, the clinical practice of OQAS II in the field of refractive cataract surgery is emphasized, including the preoperative/postoperative evaluation of visual quality, the timing of cataract surgery, the prediction of the visual quality after cataract surgery and doctor-patient communication. We hope the book provides a reference for the clinical application of the OQAS II in the field of cataract and helps to form the worldwide standard specification to a certain extent.

    Contents:
    Visual quality in the age of refractive cataract surgery
    Analysis of objective visual quality based on Double-pass technology
    Clinical significance of the main parameters of Double-pass Optical Quality Analysis System
    Acquisition mode and operation procedure of Double-pass Optical Quality Analysis System
    Clinical application of objective evaluation of tear film optical quality
    Objective classification of cataract
    Timing of cataract surgery
    Prediction of the visual quality after cataract surgery
    Doctor-patient Communication
    Comparison of cataract treatment methods
    Optimal treatment timing for posterior capsule opacification. .
    Digital Access Springer 2021
  • Digital
    Hildegard Wittlinger, Dieter Wittlinger, Andreas Wittlinger, Maria Wittlinger.
    Contents:
    Anatomy and physiology of the circulation of the blood
    Anatomy of lymph vessels and lymph nodes
    Physiology of the lymphatic system, lymph, and interstitium
    Lymphedema
    Equilibrium and balance as the aim of the massage
    Indications and contraindications for manual lymph drainage
    Effect of manual lymph drainage on the smooth muscles of blood vessels and lymphangions
    Diagnostic examination and edema measurement
    Massage techniques
    Treatments of the individual parts of the body
    Special techniques
    Treatment model for secondary lymphedema
    Complementary treatments
    Historical background.
  • Print
    John F. Strauss.
    Summary: "This compelling biography traces the life and times of pediatrician Wilhelm Strauss from his childhood in Prague and his late Hapsburg monarchy medical education in Vienna, to his practice of social medicine in Wiener Neustadt during the Julius Tandler era. It continues with the painful disruptions of the 'Anschluss' and his forced exile in Baghdad, and concludes unexpectedly in New York State, USA. Reproduced in the book are valuable documents in Strauss' own words describing the state of pediatric medicine at the beginning of the First Austrian Republic"-- back cover.
    Print Access Request
    Location
    Version
    Call Number
    Items
  • Digital
    Fiona Subotsky.
    Summary: Exploring how medicine and psychiatry are portrayed in gothic literature, this engaging book illustrates how Stoker's famous work was influenced by nineteenth-century attitudes to disease and medicine and reveals many previously unknown links. Extracts from many sensational stories of the time are presented, and the role of doctors and their appearance and contribution to gothic fiction is investigated. The book covers topics such as asylums, their purpose, practice and patients, deadly diseases echoing the symptoms of vampirism, and the otherworldly allure of the undead. Dracula for Doctors is an entertaining and informative examination of how Victorian medical knowledge and culture informed Stoker's gothic masterpiece. This book suggests that Stoker, who had many medical connections, was able to link lurid stories of operations and asylums with fictional horror and suspense. Fans of gothic literature, as well as those of medical history and the supernatural, will find this an enjoyable read.

    Contents:
    Body and mind
    Medico-gothic
    Stoker medical circles
    Asylum doctors
    The gothic asylum
    Renfield, the pet lunatic
    The other patients
    Diagnosing Dracula
    Dread, disease and the asylum
    Occult blood
    Holes in the skull
    Dead, alive or undead
    Therapeutic armamentarium
    Compelling eyes
    Beastliness
    Vivisection or animal torture?
    Demons and doctors
    Scientists and the supernatural
    And Dracula for dentists
    Sex and death.
    Digital Access Cambridge 2019
  • Digital
    Kenneth J. Tennessen.
    Summary: "This monograph is the first of its kind devoted entirely to the dragonfly nymphs of North America north of Mexico, the focus being accurate identification of the 330 species of Anisoptera that occur in the region. Nymphal external morphology is described and illustrated in detail, and all terms needed to navigate the dichotomous keys are defined. Species are tabulated with references that provide the most detailed, accurate descriptions for each; species that are inadequately described are so indicated. The key separating the seven families in the region contains several new characters. The families are then covered separately: Aeshnidae (13 genera), Gomphidae (17 genera), Petaluridae (2 genera), Cordulegastridae (2 genera), Macromiidae (2 genera), Corduliidae (7 genera), and Libellulidae (29 genera). Each family is further characterized, followed by a generic key. A drawing of the habitus and diagnostic details for each genus are provided, along with additional diagnostic remarks and notes on habitat and life cycle; for each genus, a map shows its geographic distribution in North America. Full-grown nymphs of all known species of each genus are keyed and diagnosed; characters that apply to earlier instars are noted. Morphological variation in character states was analyzed in order to assess the reliability of previously utilized characters and to discover new characters. Most of the characters used to distinguish all levels of taxa are illustrated; a total of 702 figures, comprising 1,800 original drawings, along with selected photographs where necessary for clarity, accompany the keys. Measurements of total length, head width, and other variables for each species are provided in tables. Difficulties with past keys and descriptions, including errors, omissions and other shortcomings, are addressed. The importance of nymph characters in helping solve generic and specific distinctions and their role in phylogenetic studies is emphasized. Methods for collecting, rearing, and preserving dragonfly nymphs and exuviae are presented. The final chapter discusses research opportunities on North American Anisoptera nymphs, including taxonomic needs, studies on structure and function, life history and microhabitat, water quality indices and conservation efforts. The habitus drawings of all genera are arranged according to family in five plates (Appendix I); although the book is intended as a lab manual, these plates conveniently allow for comparison based on nymph shape making field identification to genus possible in many cases. Appendix II contains a brief history of dragonfly nymph studies in North America. A glossary and an index to scientific names are included."

    Contents:
    Intro; Dedication; Preface; References; Contents; Part I: Preliminary Material;
    1: Introduction; References;
    2: Nymph Anatomy and Instar Determination; 2.1 The Head; 2.2 The Thorax; 2.3 The Abdomen; 2.4 External Morphological Outgrowths; 2.4.1 Determining Gender; 2.5 Growth; 2.5.1 Determining Instar; References;
    3: Using the Keys; 3.1 Specimen Preparation; References;
    4: List of Species Treated; 4.1 Odonata Diversity in the Americas; 4.2 The Anisoptera Fauna of North America; 4.3 State and Province Abbreviations; 4.4 Species List with Nymph References; References 12.3 Cannaphila Kirby, 188912.4 Celithemis Hagen, 1861; 12.5 Crocothemis Brauer, 1868; 12.6 Dythemis Hagen, 1861; 12.7 Erythemis Hagen, 1861; 12.8 Erythrodiplax Brauer, 1868; 12.9 Idiataphe Cowley, 1934; 12.10 Ladona Needham, 1897; 12.11 Leucorrhinia Brittinger, 1850; 12.12 Libellula Linnaeus, 1758; 12.13 Macrodiplax Brauer, 1868; 12.14 Macrothemis Hagen, 1868; 12.15 Miathyria Kirby, 1889; 12.16 Micrathyria Kirby, 1889; 12.17 Nannothemis Brauer, 1868; 12.18 Orthemis Hagen, 1861; 12.19 Pachydiplax Brauer, 1868; 12.20 Paltothemis Karsch, 1890; 12.21 Pantala Hagen, 1861
    7: Gomphidae7.1 Aphylla Selys, 1854; 7.2 Arigomphus Needham, 1897; 7.3 Dromogomphus Selys, 1854; 7.4 Erpetogomphus Selys, 1858; 7.5 Gomphurus Needham, 1901; 7.6 Hagenius Selys, 1854; 7.7 Hylogomphus Needham, Westfall and May, 2000; 7.8 Lanthus Needham, 1897; 7.9 Octogomphus Selys, 1873; 7.10 Ophiogomphus Selys, 1854; 7.11 Phanogomphus Carle, 1986; 7.12 Phyllocycla Calvert, 1948; 7.13 Phyllogomphoides Belle, 1970; 7.14 Progomphus Selys, 1854; 7.15 Stenogomphurus Carle, 1996; 7.16 Stylogomphus Fraser, 1897; 7.17 Stylurus Needham, 1897; References;
    8: Petaluridae 8.1 Tachopteryx Uhler in Selys, 18598.2 Tanypteryx Kennedy, 1917; References;
    9: Cordulegastridae; 9.1 Cordulegaster Leach, 1815; 9.2 Zoraena Kirby, 1890; References;
    10: Macromiidae; 10.1 Didymops Rambur, 1842; 10.2 Macromia Rambur, 1842; References;
    11: Corduliidae; 11.1 Cordulia Leach, 1815; 11.2 Dorocordulia Needham, 1901; 11.3 Epitheca Charpentier, 1840; 11.4 Helocordulia Needham, 1901; 11.5 Neurocordulia Selys, 1871; 11.6 Somatochlora Selys, 1871; 11.7 Williamsonia Davis, 1913; References;
    12: Libellulidae; 12.1 Brachymesia Kirby, 1889; 12.2 Brechmorhoga Kirby, 1894 Part II: Systematic
    s5: Key to the Families; 5.1 Key to Anisoptera Families of North America, F-0 to F-5; 5.1.1 Family Diagnoses; References;
    6: Aeshnidae; 6.1 Aeshna Fabricius, 1775; 6.2 Anax Leach, 1815; 6.3 Hemianax Selys, 1883; 6.4 Basiaeschna Selys, 1883; 6.5 Boyeria McLachlan, 1896; 6.6 Coryphaeschna Williamson, 1903; 6.7 Epiaeschna Hagen, 1877; 6.8 Gomphaeschna Selys, 1871; 6.9 Gynacantha Rambur, 1842; 6.10 Nasiaeschna Selys, 1900; 6.11 Oplonaeschna Selys, 1883; 6.12 Remartinia Navás, 1911; 6.13 Rhionaeschna Förster, 1909; 6.14 Triacanthagyna Selys, 1883; References
    Digital Access Springer 2019
  • Digital
    [edited by] Jan Odom-Forren.
    Contents:
    Sect. I: The postanesthesia care unit
    Sect. II: Physiologic considerations in the PACU
    Sect. III: Concepts in anesthetic agents
    Sect. IV: Nursing care in the PACU
    Sect. V: Special considerations.
    Digital Access R2Library 2018
    Limited to 2 simultaneous users
  • Digital
    [edited by] Jan Odom-Forren.
    Summary: "Drain's PeriAnesthesia Nursing: A Critical Care Approach, 8th Edition provides comprehensive clinical content tailored specifically for perianesthesia nurses. An easy-to-use format with five distinct sections -- covering the PACU, anatomy and physiology, pharmacology, nursing care, and special considerations -- means you get the equivalent of five books in one. Nursing and pharmacologic interventions are integrated with in-depth coverage of pathophysiology, and updated content includes the latest standards and current issues affecting perianesthesia nursing practice. Focusing on research, documentation, and psychosocial considerations, this is the one book that can take you all the way from being a novice nurse in the PACU to preparing for CPAN®or CAPA® certification! Five separate sections provide comprehensive coverage, including the PACU, anatomy and physiology, pharmacology, nursing care, and special considerations. Coverage of current policies and issues affecting perianesthesia nursing practice includes patient safety, infection control, managed care implications, pain management, and bioterrorism. Comprehensive information on the various types of anesthetic agents familiarizes you with what will be used in the PACU. Special Considerations section details the care of patients with conditions such as malignant hyperthermia, substance abuse, sickle cell anemia, and cardiac arrest"-- Publisher's description.

    Contents:
    Section I: The postanesthesia care unit. Space planning and basic equipment systems
    Perianesthesia nursing as a specialty
    Management and policies
    Crisis resource management in the PACU
    Infection prevention and control in the PACU
    The changing health care system and its implications for the PACU
    Patient safety and legal issues in the PACU
    Ethics in perianesthesia nursing
    Evidence-based practice and research
    Section II: Physiologic considerations in the PACU. The nervous system
    The cardiovascular system
    The respiratory system
    The renal system
    Fluids and electrolytes
    The endocrine system
    The hepatobiliary and gastrointestinal system
    The integumentary system
    The immune system
    Section III: Concepts in anesthetic agents. Basic principles of pharmacology
    Inhalation anesthesia
    Nonopioid intravenous anesthetics
    Opioid intravenous anesthetics
    Neuromuscular blocking agents
    Local anesthetics
    Regional anesthesia
    Section IV: Nursing care in the PACU. Transition from the operating room to the PACU
    Assessment and monitoring of the perianesthesia patient
    Patient education and care of the perianesthesia patient
    Postanesthesia care complications
    Assessment and management of the airway
    Pain management
    Care of the ear, nose, throat, neck, and maxillofacial surgical patient
    Care of the ophthalmic surgical patient
    Care of the thoracic surgical patient
    Care of the cardiac surgical patient
    Care of the vascular surgical patient
    Care of the orthopedic surgical patient
    Care of the neurosurgical and neurointerventional patient
    Care of the thyroid and parathyroid surgical patient
    Care of the gastrointestinal, abdominal, and anorectal surgical patient
    Care of the genitourinary surgical patient
    Care of the obstetric and gynecologic surgical patient
    Care of the breast surgical patient
    Care of the plastic and reconstructive surgical patient
    Care of the patient undergoing bariatric surgery
    Care of the ambulatory surgical patient
    Care of the laser/laparoscopic surgical patient
    Section V: Special considerations. Care of the patient with chronic disorders
    Care of the pediatric patient
    Care of the older patient
    Care of the pregnant patient
    Care of the patient with substance use disorder
    Care of the patient with thermal imbalance
    Care of the shock trauma patient
    Care of the intensive care unit patient in the PACU
    Bioterrorism and its impact on the PACU
    Cardiopulmonary resuscitation in the PACU
    International perspectives on perienesthesia nursing and competence.
    Digital Access ClinicalKey Nursing 2024
  • Digital
    Benjamin Ehrlich.
    Summary: This work contains the first English translation of the lost dream diary of Santiago Ramón y Cajal (1852-1934), the Nobel Prize-winning "father of modern neuroscience."

    Contents:
    Part 1. The founder of modern neuroscience. Cajal's legacy ; Cajal and psychology ; Cajal and dream research ; Cajal and Freudianism in Spain ; Comparing the lives of Cajal and Freud ; The effects of hypnosis and suggestion ; On the divergence of psychology and neuroanatomy ; Cajal's psyche and his readings of Freud
    "The Father of Modern Neuroscience" and his father
    The dream diary's strange fate
    Part 2. The dream diary of Santiago Ramón y Cajal. The dreams of Cajal.
    Digital Access Oxford 2016
  • Digital
    Tomoaki Shirao, Yuko Sekino, editors.
    Summary: This book is the first comprehensive review of drebrin, which plays pivotal roles in various cellular events, via forming unique actin cytoskeletons, including synapse formation and in synaptic function. Particularly the loss of drebrin from dendritic spines is used as a marker of dementia in neurological disorders such as Alzheimer's disease. Since drebrin was first identified by our group in 1985, many studies of drebrin have been done in various fields, including not only molecular biology, biophysics, cell biology, neuroscience, clinical studies, spermatogenesis, immunology, and cancer metastasis, but others as well. The structure of this book facilitates the understanding of the whole picture of studies on drebrin. The volume begins with a general introduction to drebrin, and then the chapters in the second part provide the basic knowledge for further understanding. The third part examines its function in the nervous system, and the fourth part discusses its function in the non-nervous system. This work will appeal to researchers who are interested in cytoskeletal dynamics at membrane-cytoskeletal interface as well as the number of them who use drebrin as a tool, such as a marker of synaptic function or a disease marker. This volume is kept as concise as possible in order to be understood by readers in diverse scientific disciplines"--Publisher's description.

    Contents:
    History of drebrin discovery as an general introduction. General introduction to drebrin / Tomoaki Shirao, Yuko Sekino
    Basic information about drebrin. Molecular cloning of drebrin: progress and perspectives / Nobuhiko Kojima
    Biochemistry of drebrin and its binding to actin filaments / Ryoki Ishikawa
    Phosphorylation of drebrin and its role in neuritogenesis / Phillip R. Gordon-Weeks
    Remodeling of actin filaments by drebrin a and its implications / Elena E. Grintsevich
    Cell shape change by drebrin / Kensuke Hayashi
    Drebrin in nervous system. Localization of drebrin: light microscopy study / Tomoaki Shirao, Noriko Koganezawa, Hiroyuki Yamazaki, Kenji Hanamura, Kazuyuki Imamura
    Making of a synapse: recurrent roles of drebrin a at excitatory synapses throughout life / Chiye Aoki, Ang D. Sherpa
    Drebrin in neuronal migration and axonal growth / Kenji Hanamura
    Drebrin and spine formation / Hideto Takahashi, Yusuke Naito
    Role of drebrin in synaptic plasticity / Yuko Sekino, Noriko Koganezawa, Toshiyuki Mizui, Tomoaki Shirao
    Drebrin in Alzheimer's disease / Yuta Ishizuka, Kenji Hanamura
    Drebrins and connexins: a biomedical perspective / Irina V. Majoul, Justus S. Ernesti, Eugenia V. Butkevich, Rainer Duden
    Homer, spikar, and other drebrin-binding proteins in the brain / Hiroyuki Yamazaki, Tomoaki
    Role of drebrin at the immunological synapse / Vera Rocha-Perugini, Mónica Gordon-Alonso, Francisco Sánchez-Madrid
    Drebrin regulation of calcium signaling in immune cells / Jonathan Pabon, Man Kit Law, Avery August
    Drebrin and spermatogenesis / Haiqi Chen, Michelle W.M. Li, C. Yan Cheng
    Drebrin at junctional plaques / Wiebke K. Ludwig-Peitsch
    Juxtanuclear drebrin-enriched zone / Wiebke K. Ludwig-Peitsch
    Drebrin in renal glomeruli / Wiebke K. Ludwig-Peitsch.
    Digital Access Springer 2017
  • Digital
    Pink, Daniel H.
    Summary: In today's fast-paced world, it's tough to find the time to read. But with Joosr guides, you can get the key insights from bestselling non-fiction titles in less than 20 minutes. Whether you want to gain knowledge on the go or find the books you'll love, Joosr's brief and accessible eBook summaries fit into your life. Find out more at joosr.com. Rewarding good performance and punishing the not so good is so ingrained in our approach to management that it's hard to conceive of an alternative. But there is a better way to motivate-one that taps into our human nature and lets us thrive. For.
    Digital Access eBook Comp Acad 2015
  • Digital
    Guenter B. Risse.
    Contents:
    1. Domain of contagion and confinement
    2. Framing "loathsome" diseases
    3. Tides of inertia and neglect
    4. Location: Not in my backyard
    5. Banished: sojourns of the damned
    6. Belle of California's Molokai
    7. Wary minders: custodians and caregivers
    8. Hope for cures: nature or science
    9. Modern isolation: humanizing castaways.
  • Digital
    Guy Echalier, Norbert Perrimon, Stephanie E. Mohr.
    Contents:
    1. Composition of the body fluid of Drosophilia and the design of culture media for drosophilia cells
    2. Primary cell cultures of Drosophilia embryonic cells
    3. Continuous Drosophilia cell lines established in vitro
    4. Cells or tissues in course of differentiation
    5. Hormonal control of development of insects: implications in organ or cell cultures of Drosophilia
    6. Directed genetic methods for establishing continuous cell lines
    7. Organ culture methods for the Drosophilia wing imaginal disc
    8. Functional genomics screens in Drosophilia cells
    9. CRISPR-based perturbation of gene function in Drosophilia cells
    10. Compendium of Drosophilia cell line resources and plasmid vectors at the Drosopilia Genome Resource Center
    Index.
    Digital Access ScienceDirect 2018
  • Digital
    Wu-Min Deng, editor.
    Summary: This volume provides a series of review articles that capture the advances in using the fruit fly, Drosophila melanogaster, model system to address a wide range of cancer-related topics. Articles in this book provide case studies that shed light on the intricate cellular and molecular mechanisms underlying tumor formation and progression. Readers will discover the beauty of the fly models genetic simplicity and the vast arsenal of powerful genetic tools enabling its efficient and adaptable use. This model organism has provided a unique opportunity to address questions regarding cancer initiation and development that would be extremely challenging in other model systems. This book provides a useful resource for a researcher who wishes to learn about and apply the Drosophila model to tackle fundamental questions in cancer biology, and to find new ways to fight against this devastating disease.
    Digital Access Springer 2019
  • Digital
    Masamitsu Yamaguchi, editor.
    Contents:
    1. Drosophila as a model organism
    2. Adult intestine aging model
    3. Alzheimer's Disease model system using Drosophilia
    4. Parkinson's Disease Model
    5. Repeat Expansion Disease Models
    6. Amyotrophic lateral sclerosis model
    7. Drosophila charcot-marie-tooth disease models
    8. Drosophila as a model to gain insight into the role of IncRNAs in neurological disorders
    9. Muscular dystrophy model
    10. Drosophila as a cancer model
    11. From Drosophila blood cells to human leukemia
    12. Diseases associated with mutation of replication and repair proteins
    13. Drosophila models to investigate insulin action and mechanisms underlying human diabetes mellitus
    14. Metabolomics: state-of-the -art technologies and applications on Drosophila melanogaster
    15. Humanized flies and resources for cross-species study
    16. Design for flies + of mice and men: design approaches to Drosophila melanogaster.
    Digital Access Springer 2018
  • Digital
    edited by Diana P. Bratu, Gerard P. McNeil.
    Contents:
    Drosophila melanogaster oogenesis : an overview / John M. McLaughlin and Diana P. Bratu
    Basic techniques in Drosophila ovary preparation / Letitia Thompson, Kristen Randolph, and Amanda Norvell
    Mosaic analysis in the Drosophila melanogaster ovary / Thomas Rubin and Jean-René Huynh
    Genetic mosaic analysis of stem cell lineages in the Drosophila ovary / Kaitlin M. Laws and Daniela Drummond-Barbosa
    Culturing Drosophila egg chambers and investigating developmental processes through live imaging / Lathiena Manning and Michelle Starz-Gaiano
    Border cell migration : a model system for live imaging and genetic analysis of collective cell movement / Mohit Prasad [and four others]
    Visualizing microtubule networks during Drosophila oogenesis using fixed and live Imaging / Kevin Legent, Nicolas Tissot, and Antoine Guichet
    Visualization of actin cytoskeletal dynamics in fixed and live Drosophila egg chambers / Christopher M. Groen and Tina L. Tootle
    Single-molecule RNA in situ hybridization (smFISH) and immunofluorescence (IF) in the Drosophila egg chamber / Livia V. Bayer [and three others]
    Fluorescent in situ hybridization of nuclear bodies in Drosophila melanogaster ovaries / Zehra F. Nizami, Ji-Long Liu, and Joseph G. Gall
    Ultrastructural analysis of Drosophila ovaries by electron microscopy / Thomas R. Hurd [and seven others]
    Immuno-electron microscopy and electron microscopic in situ hybridization for visualizing piRNA biogenesis bodies in Drosophila ovaries / Shinsuke Shibata [and six others]
    Visualizing cytoophidia expression in Drosophila follicle cells via immunohistochemistry / Ömür Y. Tastan and Ji-Long Liu
    Detection of cell death and phagocytosis in the Drosophila ovary / Tracy L. Meehan [and three others]
    Analysis of cell cycle switches in Drosophila oogenesis / Dongyu Jia , Yi-Chun Huang , and Wu-Min Deng
    Global run-on sequencing (GRO-seq) library preparation from Drosophila ovaries / Nikolay V. Rozhkov
    Bioinformatics analysis to identify RNA-protein interactions in oogenesis / Ravinder Singh.
    Digital Access Springer 2015
  • Digital
    edited by Joost J.L.M. Bierens.
    Summary: Since the first edition of the Handbook on Drowning in 2005, many epidemiological data have confirmed the burden of drowning in several parts of the world. Studies have increased the understanding of effective drowning prevention strategies, rescue techniques, and treatment options. Much has been learned about submersion and immersion hypothermia, SCUBA-diving injuries, the life-saving preparations of water-related disasters and how to deal with forensic investigations. In this updated second edition, experts from around the world provide a complete overview of current research data, consensus statements and expert opinions. The book Drowning provides evidence-based practical information and has a unique informative value for various groups with tasks, duties and responsibilities in this domain. In addition, the book may be an inspiration for future networks and research initiatives.

    Contents:
    Introduction
    History
    The Epidemiology of Drowning
    The Prevention of Drowning
    Rescue Organisational Aspects: Planning, Training and Preparation.- Rescue Techniques
    Resuscitation
    Hospital Treatment
    Brain Resuscitation in the Drowning Victim
    Immersion Hypothermia
    Water-related Disasters
    Breath-hold, SCUBA and Hose Diving
    Investigation of Drowning Accidents
    Important Websites.
    Digital Access Springer 2014
  • Print
    Print Access Request
    Location
    Version
    Call Number
    Items
    Books: General Collection (Downstairs)
    RC563 .D794
    1
  • Print
    edited by Jasbir M. Singh, Lyle Miller, Harbans Lal.
    Contents:
    v. 1. Experimental pharmacology
    v. 2. Clinical and socio-legal aspects
    v. 3. Neurobiology and influences on behaviour
    v. 4. New aspects of analytical and clinical toxicology.
    Print Access Request
    Location
    Version
    Call Number
    Items
    Stored offsite. Please request print.
    L566 .D78
    4
  • Digital
    Michel Burnier, editor.
    Summary: "This book provides a critical and comprehensive review of the methodologies available for measuring drug adherence in clinical practice, including those relying on emerging technologies. The authors discuss the risk factors of non-adherence and shed light on how to identify patients at risk of poor adherence. Drug therapies in chronic diseases rely heavily on the patient's adherence, since drugs that are not taken are ineffective and leave the patient at high risk of developing clinical complications. Given the absence of new drugs for the treatment of hypertension, drug adherence is particularly important in these patients to improve blood pressure control. The book further investigates a new aspect, namely the importance of drug adherence in clinical trials and studies and draws attention to the limits of developing drugs without significant information on drug adherence. Several chapters are dedicated to the importance of adherence in specific forms of hypertension, such as resistant hypertension, dyslipidemia and hypertension associated with cardiovascular risk. As experts confronted with drug adherence in their daily practice, the authors analyse the real effectiveness of several interventions aimed at improving drug adherence and put particular emphasis on the importance of an interdisciplinary approach involving nurses and pharmacists. The volume also includes a careful analysis of the health and economic impact of poor adherence. The book is aimed at physicians, pharmacists, students and all health professionals dealing not only with hypertension or dyslipidemia, but also with chronic asymptomatic diseases such as diabetes, HIV or chronic respiratory diseases."-- Provided by publisher.
    Digital Access Springer 2018
  • Digital
    by Brian A. Baldo, Nghia H. Pham.
    Summary: The second edition of this book spans the broad range of modern therapeutic drugs, from small molecules to biologic recombinant proteins. It offers a comprehensive review of the classification and description of different drug-induced systemic and cutaneous hypersensitivities; an up-to-date coverage of individual culprit drugs in each group of therapeutics; the diagnosis and mechanisms of reactions; and important structure-activity relationships. New content expands to two areas of drug allergy that have recently experienced explosive growth: biological therapies and new targeted chemotherapies. Other new and expanded chapters address antimicrobials; drugs used in anesthesia and surgery; opioids; non-targeted anti-cancer drugs; vaccines; and newly understood reaction mechanisms. This new edition includes photographs of a wide variety of cutaneous manifestations that will be of use to other clinicians as well as allergists and dermatologists. In addition to its wide clinical emphasis, the book's mechanistic and structure-activity detail will provide valuable background for researchers and investigators in universities, medical research institutes, drug companies, and regulatory agencies. The second edition of Drug Allergy is an essential reference for practitioners across the medical disciplines from specialist clinicians, surgeons, GPs, residents, and medical students to nurses, pharmacists, dentists, and those taking undergraduate and graduate courses in the biomedical sciences.

    Contents:
    Ch. 1. Adverse reactions to drugs and drug allergy
    Ch. 2. Classification and descriptions of allergic reactions to drugs
    Ch. 3. Mechanisms of hypersensitivity
    Ch. 4. Diagnosis of allergic reactions to drugs
    Ch. 5. Beta-Lactam antibiotics
    Ch. 6. Other antimicrobial drugs
    Ch. 7. Drugs and other agents used in anesthesia and surgery
    Ch. 8. Opioid analgesic drugs
    Ch. 9. Nonsteroidal anti-inflammatory drugs
    Ch. 10. Contrast media
    Ch. 11. Corticosteroids
    Ch. 12. Proton pump inhibitors
    Ch. 13. Targeted drugs for cancer therapy. Approved monoclonal antibodies
    Ch. 14. Non-targeted drugs for cancer therapy
    Ch. 15. Other approved therapeutic monoclonal antibodies
    Ch. 16. Other biologics
    Ch. 17. Vaccines.
    Digital Access Springer 2021
  • Digital
    David A. Khan, Aleena Banerji.
    Contents:
    Chapter 1. Epidemiology of drug allergy
    Chapter 2. Economic impact of drug allergy
    Chapter 3. Drug allergy: definitions and phenotypes
    Chapter 4. Immune mechanisms of drug allergy
    Chapter 5. Pharmacogenomics of drug allergy
    Chapter 6. Cutaneous reactions to drugs
    Chapter 7. Basics of skin testing and drug challenges
    Chapter 8. In vitro and in vivo tests for drug hypersensitivity reactions
    Chapter 9. Drug desensitization
    Chapter 10. Penicillins
    Chapter 11. Cephalsporin allergy
    Chapter 12. Macrolide allergy
    Chapter 13. Quinolone allergy
    Chapter 14. Sulfonamide drug allergy
    Chapter 15. Other antibiotic allergy
    Chapter 16. Multiple drug intolerance syndrome
    Chapter 17. Aspirin-exacerbated respiratory disease
    Chapter 18. Other NSAIDs reactions
    Chapter 19. Chemotherapy allergy
    Chapter 20. Hypersensitivity reactions to monoclonal antibodies
    Chapter 21. Perioperative allergy
    Chapter 22. Adverse reactions to contrast media
    Chapter 23. Corticosteroids
    Index.
    Digital Access ScienceDirect 2018
  • Digital
    [edited by] Adriana Tiziani.
    Summary: This text can be used in conjunction with Havard's Nursing Guide to Drugs 9th edition as part of the suite of resources for undergraduate and Diploma of nursing students. Each case starts with an introduction, where the presenting condition and symptoms are outlined and as the case progresses, more details of the patient's condition, tests, medications and other considerations are provided. All cases come together with a conclusion where the patient outcomes are highlighted, followed by a discussion of the key considerations for the case. Multiple Choice Questions are integrated throughout and rationales are provided for all answers. This is perfect for use during exam preparation or as a study tool, providing an engaging approach to learning and revision.

    Contents:
    Case studies
    General adult. Diabetes ; Epilepsy ; Gastrointestinal bleed ; Anticoagulation
    General paediatric. Managing acute asthma ; Management of a child with gastroenteritis ; Management of a neonate with bacterial meningitis ; Management of a child with a urinary tract infection (UTI)
    Aged care. Medication administration for the older person within a residential aged care facility ; Medication administration for the older person in the community ; Medication and the older person with dementia ; Medication administration for the older person admitted to the acute care environment
    Palliative care. Managing complex pain using opioids and adjuvant medications ; Managing breathlessness and associated anxiety ; Polypharmacy and end of life issues ; Symptom management at end of life
    Midwifery. Induction of labour and group B streptococcus (GBS) ; Elective lower segment caesarean section (LSCS) ; Threatened preterm labour and urinary tract infections (UTIs) ; Iron deficiency anaemia.
    Digital Access ClinicalKey Nursing 2016
  • Digital
    Bernardo Cortese, editor.
    Summary: This book provides a comprehensive, up-to-date summary of drug-coated balloon (DCB) technology and the role of DCBs in the treatment of coronary and peripheral arterial disease. In addition to clear explanation of how DCBs work, readers will find an enlightening analysis of the mistakes and successes of the past decade and the emergence of the latest delivery systems, which combine a more deliverable device with much improved drug delivery to the vessel wall. The full range of current applications of DCBs are reviewed in detail, drawing on the latest scientific evidence. Due attention is paid to newer devices, with provision of technical insights and documentation of the available clinical data. Ongoing research projects, remaining technical challenges, likely future directions, and reimbursement issues are also carefully considered. This book will be a useful tool for any interventional cardiologist, interventional radiologist, or vascular surgeon who wishes to acquire a deep knowledge of this technology and its application in both coronary and peripheral interventions.

    Contents:
    1 The history of drug-coated balloons
    2 Previous mistakes and how to prevent them in the future
    3 Local drug delivery to prevent restenosis of coronary and peripheral arteries
    4 Technical insights on drug-coated balloons
    5 Potential clinical advantages of DCB in specific clinical settings
    6 The role of drug-coated balloons for the treatment of coronary in-stent restenosis
    7 The role of drug-coated balloons for the treatment of native coronary vessels
    8 The role of drug-coated balloons for the treatment of coronary bifurcations.-9 Dissection management with drug-coated balloons
    10 The role of drug-coated balloons on late lumen enlargement
    11 The role of drug-coated balloons for the treatment of peripheral in-stent restenosis
    12 The role of drug-coated balloons for the treatment of native SFA
    13 The role of drug-coated balloons for the treatment of native below-the-knee arteries
    14 The role of drug-coated balloons for the treatment of other peripheral vessels
    15 Drug-coated balloons: lessons from the real world
    16 Stent use after drug-coated balloons
    17 Drug coated balloons and antithrombotic treatment
    18 Cost/effectiveness and reimbursement policies with drug-coated balloons
    19 Newer devices-technical insights & preliminary scientific data
    20 Current technical challenges and the future of drug-coated balloons.
    Digital Access Springer 2019
  • Print
    Anna Lembke, MD.
    Contents:
    1. What is addiction, who's at risk, and how do people recover?
    2. Prescription drugs as the new gateway to addiction
    3. Pain is dangerous, difference is psychopathology : the role of illness narratives
    4. Big Pharma joins Big Medicine : co-opting medical science to promote pill-taking
    5. The drug-seeking patient : malingering versus the hijacked brain
    6. The professional patient : illness as identity and a right to be compensated
    7. The compassionate doctor, the narcissistic injury, and the primitive defense
    8. Pill mills and the Toyota-ization of medicine
    9. Addiction, the disease insurance companies still won't pay doctors to treat
    10. Stopping the cycle of compulsive prescribing.
    Print Access Request
    Location
    Version
    Call Number
    Items
    Books: General Collection (Downstairs)
    RM319 .L46 2016
    1
  • Digital
    edited by Binghe Wang, Longqin Hu, Teruna J. Siahaan.
    Contents:
    1. Factors that impact the developability of drug candidates
    2. Physiological, biochemical, and chemical barriers to oral drug delivery
    3. Physicochemical properties, formulation, and drug delivery
    4. Targeted bioavailability: a fresh look at pharmacokinetic and pharmacodynamic issues in drug discovery and development
    5. The role of transporters in drug delivery and excretion
    6. Intracellular delivery and disposition of small-molecular-weight drugs
    7. Cell culture models for drug transport studies
    8. Intellectural property and regulatory issues in drug delivery research
    9. Presystemic and first-pass metabolism
    10. Pulmonary drug delivery: pharmaceutical chemistry and aerosol technology
    11. Transdermal delivery of drugs using patches and patchless delivery systems
    12. Prodrug approaches to drug delivery
    13. Liposomes as drug delivery vehicles
    14. Nanoparticles as drug delivery vehicles
    15. Evoluation of controlled drug delivery systems
    16. Pathways for drug delivery to the central nervous system
    17. Metabolic activation and drug targeting
    18. Targeted delivery of drugs to the colon
    19. Receptor-mediated drug delivery
    20. Protein and peptide conjugates for targeting therapeutics and diagnostics to specific cells
    21. Drug delivery to the lymphatic system
    22. The development of cancer theranostics: a new emerging tool toward personalized medicine
    23. Intracellular delivery of proteins and peptides
    24. Vaccine delivery: current routes of administration and novel approaches
    25. Delivery of genes and oligonucleotides
    Index.
    Digital Access Wiley 2016
  • Digital
    edited by Chun Li, Mei Tian.
    Contents:
    Introduction to molecular imaging / Vikas Kundra
    PET/SPECT : instrumentation and imaging techniques / Yuan-Chuan Tai
    Photoacoustic tomography and its application in drug delivery and photothermal therapy / Liang Song Lihong Wang
    Raman microspectral imaging for label-free detection of nanoparticle-mediated cellular and sub-cellular drug delivery / Tatyana Chernenko ... [et al.]
    Anatomical and functional MRIi / Edward F. Jackson
    Quantitative imaging in drug delivery / Kooresh Shoghi
    PET imaging of small-molecular-weight drug pharmacokinetics / Stephen M. Moerlein and Zhude Tu
    Imaging peptides, proteins, and antibody delivery / F. L. Giesel and C. Kratochwil
    In vivo imaging and delivery of siRNA / Zdravka Medarova and Anna Moore
    Imaging cell therapy / Yijie Linag and Jeff W.M. Bulte
    Radiolabeled liposomes as drug delivery nano-theranostics / William T. Phillips ... [et al.]
    Polymeric micelles as imaging agents and drug delivery systems / Jun Zhao and Chun Li
    Perfluorocarbon nanoparticles: translating bench opportunities to the clinic / G.M. Lanza ... [et al.]
    Cancer theranostics with hollow gold nanospheres / Wei Lu and Chun Li
    Imaging pulmonary drug delivery / Stephen Newman
    In-vivo imaging for validation of oral dose performance / Fiona McInnes and Howard Stevens
    Role of large animal models in translational studies of imaging and targeted drug delivery / Rajesh K. Uthamanthil and Mei Tian
    Imaging transcatheter delivery to liver tumors / Adil AL-Nahhas, Meeran Naji, Imene Zerizer
    Direct visualization of therapeutic radionuclides distribution using nuclear medicine imaging: i-131 in metastatic thyroid carcinoma / Ho Young Lee ... [et al.]
    Imaging drug delivery to the cns using translational positron emission tomography studies / Chi-Ming Lee, Katarina Varns.
    Digital Access Wiley 2014
  • Digital
    Jayvadan K. Patel, Vijaykumar Sutariya, Jagat Rakesh Kanwar, Yashwant V. Pathak, editors.
    Summary: This book addresses the issues relating to a wide variety of ocular diseases from which millions of people suffer. Long-term challenges include visual impairment and ocular blindness. Certain ocular diseases are quite rare, whereas others, such as cataracts, age-related macular degeneration (AMD), and glaucoma, are very common, especially in the aging population. A rapid expansion of new technologies in ocular drug delivery and new drug candidates, including biologics, to treat these challenging diseases in the retina and posterior segments of the eye have recently emerged. These approaches are necessary because the eye has many unique barriers to drug delivery. Thus, this timely reference Drug Delivery for the Retina and Posterior Segment Disease compiles and analyzes recent advances in the research and development of drug delivery systems for retina and posterior segment diseases of the eye, with an emphasis on the use of implantable devices, iontophoresis as well as micro- and nanoparticles.

    Contents:
    Intro; Foreword; Preface; Contents; Contributors; Part I: Introduction and Basic Concept of Drug Delivery for Retina and Posterior Segment Disease;
    Chapter 1: Anatomy and Physiology of Retina and Posterior Segment of the Eye; Introduction; Sensory Retina; Foveal Cytoarchitecture; Synaptic Connectivity; Uveal Arterial Circulation; Development and Anatomy of the Central Retinal Artery; Barrier System of the Retina; Optic Disc and Cup; Laminar Organization of the Optic Disc; Prelaminar Part; Laminar Region; Postlaminar Region; Myelination of the Ganglionic Axons
    Chapter 3: Drug Delivery to Posterior Segment of the Eye: Conventional Delivery Strategies, Their Barriers, and RestrictionsIntroduction; Posterior Segment of the Eye; Drug Delivery Strategies for Posterior Eye, Their Barriers, and Restrictions; Topical Drug Application; Systemic Drug Delivery; Intravitreal Route; Periocular Route or Transscleral Diffusion; Transscleral Iontophoresis; Ocular Implants; References;
    Chapter 4: Penetration Routes to Retina and Posterior Segment; Introduction; Systemic Route; Topical Route; Periocular and Suprachoroidal Routes; Intraocular Routes; Conclusion Metabolic Activity of the RPE and the PhotoreceptorsModulatory and Protective Role of the RPE; Optic and Non-optic Retina; Physiologic Properties of the Photoreceptors; Retinal Pathways and Synaptic Integration; Pupillary Light Reflex and Circadian Rhythm; Conclusions; References;
    Chapter 2: Pharmacotherapy of Diabetic Macular Edema and Retinopathy; Introduction; Diabetic Retinopathy; Characteristics of Diagnosis; Treatments and Therapy; Diabetic Macular Edema; Characteristics of Diagnosis; Treatments and Therapy; Conclusion; Future Trends; References Specific Anti-VEGF DrugsOther Methods of Treatment; Routes of Drug Delivery; Conclusion; References; Part II: Nanotechnology Based Formulations for Retina and Posterior Segment Disease;
    Chapter 6: Liposomes for Retina and Posterior Segment Disease; Introduction; Liposomes; Drug Loading; Drug Delivery; Targeted Drug Delivery; Application in Ocular Drug Delivery; Role of Surface Charge and Vesicle Type in Liposome-Corneal Interaction; Passive Targeting Drug-Encapsulated Liposomes; Low Molecular Weight Chitosan-Coated Liposomes
    Digital Access Springer 2018
  • Digital
    Célia Luiza Petersen Vitello Kalil, Valéria Campos, editors.
    Summary: Skin accounts for approximately 15% of an adult's total body weight, with a surface of about 2m². It provides an entry and exit barrier to various substances, offers effective protection against harmful substances, microorganisms and ultraviolet radiation, and is also paramount in immunology and body homeostasis, preventing dehydration and loss of essential minerals. The topical route has a number of advantages over oral and parenteral routes: no first-pass metabolism, greater convenience resulting in better treatment compliance, lower side-effect frequency, and prompt dosing cessation if required. However, the stratum corneum allows penetration of only 1 to 5% of substances applied topically, making this application route much less efficient. Lipophilic and small molecules (up to 500 Da) can cross the stratum corneum, since keratinocytes are covered by a lipid matrix, while it is virtually impossible for hydrophilic and large drugs to cross intact, normal skin, which means that passive topical delivery is restricted. To address this, techniques have been developed aimed at optimizing drug skin penetration by means of chemical, mechanical and physical methods, such as adding permeating active agents and using occlusion, iontophoresis, microneedling, lasers and intense pulsed light, and it is now possible to deliver medication to different skin layers or transdermally to the systemic circulation. Drug delivery is a hot topic in dermatology, with a Pubmed search generating 203431 articles. Offering a detailed review of this emerging therapeutic option, including the various methods available, this unique book guides physicians and doctors in selecting the correct technologies, technique and products for each patient. .

    Contents:
    Chapter 1. Understanding Skin and Drug Delivery
    Chapter 2. How to Optimize Drug Delivery in Dermatology?
    Chapter 3. Dermatological Applications of Drug Delivery Systems
    Chapter 4. Drug Delivery-Associated Dermatological Technologies and Techniques
    Chapter 5. Microneedling and Drug Delivery
    Chapter 6. Intense Pulsed Light and Drug Delivery
    Chapter 7. Fractional Non-Ablative Laser and Drug Delivery
    Chapter 8. Ablative Fractional Lasers & Drug Delivery
    Chapter 9. Switched and Drug Delivery
    Chapter 10. Radiofrequency, Infra-red and Others Technologies for Drug Delivery
    Chapter 11. Drug Delivery in the Treatment of Alopecia
    Chapter 12. Digital Microneedling and Drug Delivery
    Chapter 13. Active Agents in Injectable Drug Delivery
    Chapter 14. Microinfusion of Drugs into the Skin (MMP®) & Drug Delivery
    Chapter 15. Protocols for Drug Delivery.
    Digital Access Springer 2021
  • Digital
    editor, Alejandro D. Ricart.
    Contents:
    Drug-delivery systems in cancer therapy / Alejandro D. Ricart
    Drug-delivery considerations in oncology / Alejandro D. Ricart
    Antibody-drug conjugates / Alejandro D. Ricart
    Fusion proteins / Samir Dalia & Salvador Bruno
    Polymer-drug conjugates / Núria Mulet-Margalef, Josep Maria Miquel & Jordi Rodon
    Drug protein-bound particles and polysaccharide-drug conjugates / Karina A. Peters, Matías Chacón & Alejandro D. Ricart
    Liposomal drug carriers / Daniel S. Lewi, Karina A. Peters & Pedro M. Polit.
    Digital Access Future Med 2014
  • Digital
    edited by Kewal K. Jain, Jan PharmaBiotech, Basel, Switzerland.
    Contents:
    Current Status and Future Prospects of Drug Delivery Systems
    A Method for Screening Mitochondrial Fusogenic Envelopes for use in Mitochondrial Drug Delivery
    Ultrasound-directed, Site-specific Gene Delivery
    Synthesis of Thermoresponsive Polymers for Drug Delivery
    Recombinant Stem Cells as Carriers for Cancer Gene Therapy
    Microfluidic-based Manufacture of siRNA-lipid Nanoparticles for Therapeutic Applications
    Microneedle-iontophoresis Combinations for Enhanced Transdermal Drug Delivery
    Polymer Nanoparticle-based Controlled Pulmonary Drug Delivery
    Antibody Labeling with Radioiodine and Radiometals
    Self Assembling Peptide -based Delivery of Therapeutics for Myocardial Infarction
    Applications of Chitosan Nanoparticles in Drug Delivery
    A Method for Evaluating Nanoparticle Transport through the Blood Brain Barrier in vitro
    Bacterial Systems for Gene Delivery to Systemic Tumours
    Synthesis of a Smart Nanovehicle for Targeting Liver
    Intranasal Delivery of Chitosan-siRNA Nanoparticle Formulation to the Brain
    Intrathecal Delivery of Analgesics.
    Digital Access Springer 2014
  • Digital
    editor, Anthony J Hickey, RTI International, Research Triangle Park, NC, USA ; consulting editors, Amit Misra, CSIR Central Drug Research Institute, Lucknow, India, P. Bernard Fourie, University of Pretoria, Pretoria, South Africa.
    Digital Access Wiley 2016
  • Digital
    Margareta Hammarlund-Udenaes, Elizabeth C.M. de Lange, Robert G. Thorne, editors.
    Summary: This book describes the different approaches for drug delivery to the brain with an emphasis on the physiology of the blood-brain barrier (BBB) and the governing principles and concepts for drug delivery across the BBB. It contains cutting-edge methods for studying drug delivery and administering drugs into the brain. The book also explores different approaches for predicting human brain concentrations as well as the influence of disease and drug industry perspectives. In addition to wide-ranging coverage of physiological concepts relevant to central nervous system (CNS) drug delivery, a detailed review of brain structure, function, blood supply and fluids is also provided. In each chapter, descriptions of future challenges and unresolved questions are combined with points for discussion. This unique combination of material makes this book a valuable resource for students and for established academic and industry scientists looking to learn about state-of-the-art drug delivery research. It is also a source for stimulating new ideas among experts already performing CNS drug delivery research or working in related areas. Margareta Hammarlund-Udenaes (Ph.D.) is a Professor in Pharmacokinetics and Pharmacodynamics (PK/PD) at Uppsala University and the Head of the Translational PK/PD Group. Her research is focused on studying pharmacokinetic aspects of BBB transport of drugs in relation to CNS effects, and it has led to the development of new concepts and methods within the BBB transport area, focusing on unbound drug relationships. Elizabeth C.M. de Lange (Ph.D.) is Head of the Target Site Equilibration Group at the Division of Pharmacology of the Leiden Academic Center for Drug Research (LACDR). Her research program focuses on the development of generally applicable predictive PK/PD models on CNS drugs using advanced in vivo animal models and mathematical modeling techniques, with a number of recent successes. Robert G. Thorne (Ph.D.) is an Assistant Professor in Pharmaceutical Sciences at the University of Wisconsin-Madison School of Pharmacy. He was previously a research scientist and faculty member in the Department of Physiology & Neuroscience at the New York University School of Medicine. His research focuses on diffusive and convective transport within the CNS and the development, refinement and optimization of strategies for delivering biologics into the brain.

    Contents:
    Part I. Physiology and basic principles for drug handling by the brain
    Part II. Pharmacokinetic concepts in brain drug delivery
    Part III. Industrial approaches for investigation of potential central nervous system drugs
    Part IV. Strategies for improved central nervous system drug delivery
    Part V. Brain drug delivery in disease conditions.
    Digital Access Springer 2014
  • Digital
    edited by Atta-ur-Rahman, FRS, Honorary Life Fellow, Kings College, University of Cambridge, UK and Muhammad Iqbal Choudhary, H.E.J. Research Institute of Chemistry, International Center for Chemical and Biological Sciences, University of Karachi, Pakistan.
    Digital Access ScienceDirect 2014
  • Digital
    Madhu Dikshit, editor.
    Springer Nature eBook.
    Summary: Over the years, India has attained a prominent global position in the manufacture of Generic Drugs. This success can be attributed to its synthetic organic chemistry and chemical engineering strengths, nurtured by the timely policies of the Government of India. However, breakthrough successes in New Drug Discovery have remained elusive, despite the brilliant and sustained efforts of many Indian researchers and Pharma establishments. The Indian National Science Academy thought it appropriate to document Indias New Drug Discovery Research (NDDR) journey to date. Gathering contributions from prominent researchers in the Indian Pharma Industry and Academia, this book highlights their efforts, achievements, and the status quo of Indian NDDR. .

    Contents:
    Chapter 1. Traditional Medical System (TMS) for Sustainable Healthcare in India
    Chapter 2. Modern Drug Discovery and Development for TB- The India Narrative
    Chapter 3. Indian Discovery Effort in the Quest of Novel Antibiotics
    Chapter 4. New Drug Discovery and Development in India to Counter Malaria
    Chapter 5. Modern Drug Discovery and Development in the area of Leishmaniasis
    Chapter 6. Modern Drug Discovery and Development: Diabetes and lifestyle disorders Part I Introduction to Diabetes and Prevalence in India
    Chapter 7. Modern Drug Discovery and Development: Diabetes and lifestyle disorder Part II Type 2 Diabetes Mellitus: Marketed drugs and mechanisms
    Chapter 8. Modern Drug Discovery and Development: Diabetes and lifestyle disorders Part III Anti-diabetes research in India: Contributions from industrial organizations
    Chapter 9. Modern Drug Discovery and Development: Diabetes and lifestyle disorders Part IV Indian Academia Tryst with Cardio-metabolic Drug Discovery and Development
    Chapter 10. Modern drug discovery and development in the area of Cancer: Indian context
    Chapter 11. Biopharmaceutical development in India: recommendations on collaboration and innovation to enable affordable healthcare
    Chapter 12. Regulatory requirements and Quality Standards in Indias Clinical Trials Journey
    Chapter 13. Indian Pharma Perspective: New Drug Discovery and Development- Indian Pharmaceutical Industry.
    Digital Access Springer 2021
  • Digital/Print
    Subash Chandra Gupta, Sahdeo Prasad, Bharat B. Aggarwal, editors.
    Summary: "Second comprehensive volume focuses on anti-inflammatory nutraceuticals and their role in prevention and therapy of various chronic diseases. Food and drug administration (FDA) approved drugs such as steroids, non-steroidal anti-inflammatory drugs (NSAIDS), statins and metformin have been shown to modulate inflammatory pathways, but their long-term intake has been associated with numerous side effects. Thus dietary agents which can modulate inflammatory pathways in humans, are likely to exhibit enormous potential. Leading experts describe the latest results of anti-inflammatory nutraceuticals and their role in prevention and therapy of various chronic diseases"--Publisher's description.

    Contents:
    Cinnamon and chronic diseases / Mitra Hariri, Reza Ghiasvand
    Silymarin and its role in chronic diseases / Neha, Amteshwar S. Jaggi, Nirmal Singh
    Eugenol and its role in chronic diseases / S. Fujisawa, Y. Murakami
    Catechins and its role in chronic diseases / Yohei Shirakami, Hiroyasu Sakai, Takahiro Kochi, Mitsuru Seishima, Masahito Shimizu
    Capsaicin and its role in chronic diseases / E. S. Fernandes, A. R. A. Cerqueira, A. G. Soares, Soraia K. P. Costa
    Diallyl sulfide and its role in chronic diseases prevention / Shankar Suman, Yogeshwer Shukla
    Lupeol and its role in chronic diseases / Fan-Shiu Tsai, Li-Wei Lin, Chi-Rei Wu
    Gingerol and its role in chronic diseases / Yasmin Anum Mohd Yusof
    Potential use of flavopiridol in treatment of chronic diseases / Thejal Srikumar, Jaya Padmanabhan
    Plumbagin and its role in chronic diseases / Pharkphoom Panichayupakaranant, Md Iftekhar Ahmad
    Anethole and its role in chronic diseases / Ana Clara Aprotosoaie, Irina-Iuliana Costache, Anca Miron
    The role of indirubins in inflammation and associated tumorigenesis / Xinlai Cheng, Karl-Heinz Merz
    CDDO and its role in chronic diseases / Bryan J. Mathis, Taixing Cui
    Evodiamine and its role in chronic diseases / Qunyou Tan, Jingqing Zhang
    Guggulsterone and its role in chronic diseases / Takanori Yamada, Ken Sugimoto
    Deguelin and its role in chronic diseases / Jonathan Boyd, Alice Han
    Quercetin and its role in chronic diseases / Ganiyu Oboh, Ayokunle O. Ademosun, Opeyemi B. Ogunsuyi
    Eucalyptol and its role in chronic diseases / Geun Hee Seol, Ka Young Kim
    Auraptene and its role in chronic diseases / Giuseppe Derosa, Pamela Maffioli, Amirhossein Sahebkar.
    Digital Access Springer 2016
  • Print
    Carmen, Andrew.
    Print
    Location
    Version
    Call Number
    Items
    Books: General Collection (Downstairs)
    Call number varies. Search for Drug discovery series to find individual volumes of this title.
  • Digital
    edited by Yvonne Will, J. Eric McDuffie, Andrew J. Olaharski, Brandon D. Jeffy.
    Summary: As a guide for pharmaceutical professionals to the issues and practices of drug discovery toxicology, this book integrates and reviews the strategy and application of tools and methods at each step of the drug discovery process. - Guides researchers as to what drug safety experiments are both practical and useful- Covers a variety of key topics - safety lead optimization, in vitro-in vivo translation, organ toxicology, ADME, animal models, biomarkers, and -omics tools- Describes what experiments are possible and useful and offers a view into the future, indicating key areas to watch for new predictive methods- Features contributions from firsthand industry experience, giving readers insight into the strategy and execution of predictive toxicology practices
    Digital Access Wiley 2016
  • Digital
    Syed Tabish R. Zaidi and Jason A. Roberts, edtiors.
    Contents:
    Betalactams: Penicillins
    Betalactams: Cephalosporins
    Aminoglycosides
    Quinolones
    Carbapenems
    Glycopeptides and antibiotics for Gram-Positive Bacterial Infections
    Azole antifungals
    Echinocandins antifungals
    Polyene antifungals
    Miscellaneous antimicrobials. .
    Digital Access Springer 2016
  • Digital
    Haur Yueh Lee, Daniel Creamer, editors.
    Summary: Cutaneous adverse drug reactions are common and range from the benign to those which are life-threatening. The clinical presentation of these dermatoses is varied and many may mimic common skin conditions. Consequently, diagnosis in drug-induced skin disease is challenging and the treatment considerations are complex. This book aims to bridge the divide between dermatology and allergy by providing a comprehensive review on the pathomechanisms and clinical features of cutaneous adverse drug reactions. Broken up into three distinct sections: General Considerations, Reaction Patterns, and Special Drug Categories, these chapters cover the common and rare adverse skin reactions and provide information on recent advances - particularly immunopathology and pharmacogenetics - as well as highlighting new adverse drug signals and novel therapies. Drug Eruptions is a must-have resource for dermatologists, allergists, internal physicians and general practitioners.

    Contents:
    Section I: General Considerations
    Chapter 1: Pharmacogenetics of Cutaneous Adverse Drug Reactions
    Chapter 2: Mechanisms of Drug Hypersensitivity
    Chapter 3: Histopathology of Cutaneous Adverse Drug Reactions
    Chapter 4: Skin Tests in Evaluating Drug Eruptions
    Chapter 5: In vitro Drug Allergy Testing
    Section II: Reaction Patterns
    Chapter 6: Drug-induced urticaria
    Chapter 7: Exanthematous Drug Eruptions
    Chapter 8: Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis
    Chapter 9: Acute Generalized Exanthematous Pustulosis
    Chapter 10: Drug Reaction Eosinophilia and Systemic Symptoms (DRESS)
    Chapter 11: Fixed Drug Eruptions and Generalized Bullous Fixed Drug Eruptions
    Chapter 12: Lichenoid Drug Eruptions
    Chapter 13: Drug-induced Connective Tissue Disorders
    Chapter 14: Drug-induced Vasculitis
    Chapter 15: Drug-induced Autoimmune Bullous Diseases
    Chapter 16: Other Drug-induced Inflammatory Skin Reactions
    Chapter 14: Drug-induced Vasculitis
    Chapter 15: Drug-induced Autoimmune Bullous Diseases
    Chapter 16: Other Drug-induced Inflammatory Skin Reactions
    Chapter 17: Drug-induced Photosensitivity
    Chapter 18: Drug-induced Pruritus Without Primary Rash
    Chapter 19: Drug-induced Nail Changes
    Chapter 20: Drug-induced Hair Changes
    Chapter 21: Drug-induced Pigmentary Disorders
    Section III: Special Drug Categories
    Chapter 22: Immediate and Delayed Reactions to Beta-lactams
    Chapter 23: Hypersensitivity Reactions to Iodinated Radiocontrast Media
    Chapter 24: Cutaneous Adverse Reactions to Biologic Agents
    Chapter 25: Cutaneous Reactions to Oncologic Targeted Therapy
    Chapter 26 :Cutaneous Reactions to Oncologic Immunotherapy. .
    Digital Access Springer 2022
  • Digital
    Kewal K. Jain.
    Summary: This book is a first-of-its kind reference that systematically organizes and describes the adverse effects of drugs on the nervous system. Drug safety is recognized as an important aspect of pharmaceutical companies as well as practice of medicine. Chapters include case reports of adverse effects of drugs that are published as well as reported to drug manufacturers. The book scope is broad as it covers lack of efficacy, drug resistance, drug-disease and drug-drug interactions. This information is used to improve the use of drugs as well as to design better and safer drugs for the future, and is relevant to personalized medicine in trying to match the right drugs to the patients. Drug-induced Neurological Disorders offers a unique approach to this important topic by integrating clinical neurology with pharmacology with a focus on effects of drugs on the nervous system including those used for the treatment of neurological disorders as well systemic diseases. Many adverse effects involve multiple systems of the body and the syndromes with predominant effect on the nervous system are included in this book.

    Contents:
    1. Introduction, history and epidemiology of drug-induced neurological disorders
    2. Neurologic symptoms as adverse drug reactions
    3. Role of the blood-brain barrier in effects of drugs on the brain
    4. Pathomechanisms of drug-induced neurological disorders
    5. Adverse effects of drugs on the fetal nervous system
    6. Principles of management of drug-induced neurological disorders
    7. Methods of drug delivery to the nervous system and DIND
    8. Neurological complications of anesthesia
    9. Neurological complications of cancer therapies
    10. Adverse effects of biological therapies on the nervous system
    11.Drug-induced aseptic meningitis
    12. Drug-induced intracranial hypertension
    13. Drug-induced encephalopathies
    14. Drug-induced disorders of memory and dementia
    15. Drug-induced disturbances of consciousness
    16. Drug-induced neuro-psychiatric disorders
    17. Neurological effects of drug abuse
    18. Drug-induced sleep disorders
    19. Drug-induced seizures
    20. Drug-induced movement disorders
    21. Tardive dyskinesia
    22. Drug-induced headaches
    23. Drug-induced cerebrovascular disorders
    24. Drug-induced disorders of cranial nerves
    25. Drug-induced neurootological disorders
    26. Drug-induced neuro-ophthalmological disorders
    27. Drug-induced disorders of smell and taste
    28. Drug-induced peripheral neuropathies
    29. Drug-induced disorders of the autonomic nervous system
    30. Drug-induced neuromuscular disorders
    31. Drug-induced myopathies
    32. Drug-induced spinal disorders
    33. Drug-induced cerebellar disorders
    34. Eosinophilia-myalgia syndrome
    35. Drug-induced pituitary disorders
    36. Serotonin syndrome
    37. Drug-induced Guillain-Barré syndrome
    38. Neuroleptic malignant syndrome.
    Digital Access Springer 2021
  • Digital/Print
    Frederick "Fritz" T. Fraunfelder, Frederick "Rick" W. Fraunfelder, Wiley A. Chambers ; associate editor, Bree Jensvold-Vetsch.
    Digital Access ScienceDirect 2015
    Print
    Location
    Version
    Call Number
    Items
    Reference (Upstairs)
    RE994 .F7 2015
    1
  • Digital
    Frederick "Fritz" T. Fraunfelder and Frederick "Rick" W. Frauenfelder.
    Contents:
    National Registry of Drug-Induced Ocular Side Effects
    Ocular drug delivery and toxicology
    Methods for evaluating drug-induced visual side effects
    Anti-infectives
    Drugs affecting the central nervous system
    Drugs affecting the autonomic nervous system
    Analgesics, narcotic antagonists, and drugs used to treat arthritis
    Drugs used in anesthesia
    Gastrointestinal drugs
    Cardiac, vascular, and renal drugs
    Hormones and drugs affecting hormonal mechanisms
    Drugs affecting blood formation and coagulability
    Homeostatic and nutrient drugs
    Drugs used to treat allergic and neuromuscular disorders
    Oncolytic drugs
    Heavy metal antagonists and miscellaneous drugs
    Drugs used in the management of human immunodeficiency virus/acquired immunodeficiency syndrome
    Drugs used in ophthalmology
    Herbal medicine– and dietary supplement–induced ocular side effects.
    Digital Access ClinicalKey 2021
  • Digital
    Sarah Cousty and Sara Laurencin-Dalicieux, editors.
    Contents:
    Adverse Drug Reactions in the Orofacial Region: How Does it Work?
    Drug-Induced Gingival Overgrowth
    Drug-Induced Oral Mucosa Pigmentation
    Oral Manifestations of Drug Allergy
    Drug-Induced Oral Ulcerations
    Drug-Induced Oral Lichenoid Reactions / White Lesions
    Drug-Induced Osseous Complications
    Drug-Induced Oral Bleeding
    Drug-Induced Taste Disturbances
    Drug-Induced Salivary Gland Disturbances : Xerostomia, Pain, Swelling, Hypersalivation, Discoloration of Saliva
    Drug-Induced Oral Infections
    Drug-Induced Peri-Oral and Facial Complications.
    Digital Access Springer 2021
  • Digital
    [edited by] Nico de Vries, Ottavio Piccin, Olivier M. Vanderveken, Claudio Vicini.
    Summary: "Obstructive sleep apnea is the most prevalent sleep-related breathing disorder, impacting an estimated 1.36 billion people worldwide. In the past, OSA was almost exclusively treated with Continuous Positive Airway Pressure (CPAP), however, dynamic assessment of upper airway obstruction with Drug-Induced Sleep Endoscopy (DISE) has been instrumental in developing efficacious alternatives. Drug-Induced Sleep Endoscopy: Diagnostic and Therapeutic Applications by Nico de Vries, Ottavio Piccin, Olivier Vanderveken, and Claudio Vicini is the first textbook on DISE written by world-renowned sleep medicine pioneers"-- Provided by publisher.
    Digital Access
    Provider
    Version
    Thieme-Connect
    Thieme MedOne Otolaryngology
  • Digital
    editors, Patrick M. Malone, Meghan J. Malone, and Sharon K. Park.
    Contents:
    Introduction to the concept of drug information
    Formulating an effective response: a structured approach
    Drug information resources
    Drug literature evaluation I: controlled clinical trial evaluation
    Literature evaluation II: beyond the basics
    The application of statistical analysis in the biomedical sciences
    Pharmacoeconomics
    Evidence-based clinical practice guidelines
    Journal clubs
    Legal aspects of drug information practice
    Ethical aspects of drug information practice
    Professional communication of drug information
    Pharmacy and therapeutics committee
    Drug evaluation monographs
    Drug shortages and counterfeit drugs
    Quality improvement and the medication use system
    Medication misadventures I: adverse drug reactions
    Medication misadventures II: medication and patient safety
    Policy, procedure, and guideline development
    Project management
    Investigational drugs
    Pharmaceutical industry and regulatory affairs
    Assessing drug promotions
    Drug information in ambulatory care
    Drug information and contemporary community pharmacy practice
    Pharmacy informatics: enabling safe and efficacious medication use
    Drug information education and training
    Appendices
    Glossary
    Answers for case studies
    Answers for self-assessment questions
    Digital Access AccessPharmacy 2018
  • Print
    the Mediphor Editorial Group, Division of Clinical Pharmacology, Stanford University School of Medicine ; editor, Richard J. Mangini ; editorial board, Terrence F. Blaschke, Stanley N. Cohen, David S. Tatro.
    Print Access Request
    Location
    Version
    Call Number
    Items
    Retired Reference (Downstairs)
    1983-2014.
    including updates
    RM302 .D794
    4
  • Print
    Vasta, Bruno M.
    Contents:
    v. 1. 1967-1970
    v. 2. 1970-1971.
    Print Access Request
    Location
    Version
    Call Number
    Items
    Stored offsite. Please request print.
    Z6675.P5 U56
    2
  • Digital
    Manjunath P. Pai, Jennifer J. Kiser, Paul O. Gubbins, Keith A. Rodvold, editors.
    Summary: The 4th edition of Drug Interactions in Infectious Diseases is being split into two separate volumes – “Mechanisms and Models of Drug Interactions” and “Antimicrobial Drug Interactions”. This volume, “Antimicrobial Drug Interactions,” delivers a quick clinical resource that distills relevant drug interactions by antimicrobial drug class. The book provides informative tables on specific drug-drug interactions that include the degree and severity of the expected interaction. A mechanistic basis for drug-drug interactions is also provided to link observed interactions to pharmacologic characteristics of key drug classes. This complete resource is organized by major antibacterial, antimycobacterial, antiviral, antifungal, antimalarial, and antiprotozoal class. In line with current innovations in antimicrobial drug development, a distinct chapter on the pharmacologic management of drug interactions in hepatitis B virus (HBV) and hepatitis C virus (HCV)-related infections is included.  Two new chapters are dedicated to the management of human immunodeficiency virus (HIV) drug-drug interactions given the breadth of antiretroviral class-specific effects. This comprehensive review of known drug interactions and strategies to manage them is an invaluable resource to all health care practitioners.

    Contents:
    Beta-Lactam Antibiotics
    Macrolides, Azalides, and Ketolides
    Quinolones
    Glycopeptides, Lipopeptides, and Lipoglycopeptides
    Miscellaneous Antibiotics
    Drugs for Tuberculosis
    Drug Interactions in HIV: Protease and Integrase Inhibitors
    Drug Interactions in HIV:  Nucleoside, Nucleotide, and Nonnucleoside Reverse Transcriptase Inhibitors and Entry Inhibitors
    Hepatitis B and Hepatitis C Antiviral Agents
    Drug Interactions of Non-HIV Antiviral Agents
    Antifungal Agents
    Antimalarial Agents
    Antiprotozoal and Anthelminthic Agents.
    Digital Access Springer 2018
  • Digital
    edited by Manjunath P. Pai, Jennifer J. Kiser, Paul O. Gubbins, Keith A. Rodvold.
    Summary: The 4th edition of Drug Interactions in Infectious Diseases is being split into two separate volumes - "Mechanisms and Models of Drug Interactions" and "Antimicrobial Drug Interactions". This volume, "Mechanisms and Models of Drug Interactions," delivers a text that enhances clinical knowledge of the complex mechanisms, risks, and consequences of drug interactions associated with antimicrobials, infection, and inflammation. The book provides a comprehensive review of basic clinical pharmacology with a focus on metabolism and transporter-mediated drug interactions. The chapters address materials that cannot be retrieved easily in the medical literature, including materials focused on the complex interrelationship of acute infection, inflammation, and the risk of drug interactions in the Drug-Cytokine chapter. The Food-Drug and Herb-Drug interactions chapters remain definitive resources. A new chapter on in vitro modeling of drug interactions is included along with updates on design and data analysis of clinical drug interaction studies. Authoritative discussion of models for regulatory decision-making on drug-drug interactions provides the necessary framework to aid antimicrobial drug development. This concise review of the mechanisms and models of drug interactions provides important insights to health care practitioners as well as scientists in drug development.

    Contents:
    Introduction to Drug-Drug Interactions
    Mechanisms of Drug Interactions I: Absorption, Metabolism, and Excretion
    Mechanisms of Drug Interactions II: Transport Proteins
    Drug-Food Interactions
    Drug-Cytokine Interactions
    Interactions between Herbs and Antiinfective Medications
    In vitro Modeling of Drug-Drug Interactions
    Probe Cocktail Studies
    Design and Data Analysis in Drug Interaction Studies.
    Digital Access Springer 2018
  • Digital
    edited by Kenneth K.W. To and William C.S. Cho.
    Summary: "Drug Repurposing in Cancer Therapy: Approaches and Applications provides comprehensive and updated information from experts in basic science research and clinical practice on how existing drugs can be repurposed for cancer treatment. The book summarizes successful stories that may assist researchers in the field to better design their studies for new repurposing projects. Sections discuss specific topics such as in silico prediction and high throughput screening of repurposed drugs, drug repurposing for overcoming chemoresistance and eradicating cancer stem cells, and clinical investigation on combination of repurposed drug and anticancer therapy"--Publisher's description.

    Contents:
    Drug repurposing for cancer therapy--an introduction
    A ligand-centric approach to identify potential drugs for repurposing: case study with aurora kinase inhibitors
    Machine learning strategies for identifying repurposed drugs for cancer therapy
    Unveiling potential anticancer drugs through in silico drug repurposing approaches
    Increasing opportunities of drug repurposing for treating breast cancer by the integration of molecular, histological, and systemic approaches
    The success story of drug repurposing in breast cancer
    A personalized medicine approach to drug repurposing for the treatment of breast cancer molecular subtypes
    Successful stories of drug repurposing for cancer therapy in hepatocellular carcinoma
    Stories of drug repurposing for pancreatic cancer treatment--Past, present, and future
    Animal models and in vivo investigations for drug repurposing in lung cancer
    Identification of chemosensitizers by drug repurposing to enhance the efficacy of cancer therapy
    Drugs repurposed to potentiate immunotherapy for cancer treatment
    Nanoparticle-based formulation for drug repurposing in cancer treatment
    Nanotechnological approaches in cancer: the role of celecoxib and disulfiram
    Clinical trials on combination of repurposed drugs and anticancer therapies.
    Digital Access ClinicalKey 2020
  • Digital
    Alicia Ponte-Sucre, Maritza Padrón-Nieves, editors.
    Summary: Providing a comprehensive review of the epidemiology and pathology of Leishmania and Leishmaniasis, this book offers a close examination of this parasitic disease and its resistance to drugs, including its molecular basis, consequences and possible treatments.

    Contents:
    Leishmaniasis : the biology of a parasite
    Determinant features in leishmaniasis
    Molecular evolution and phylogeny of leishmania
    The role of reservoirs : cananie leishmaniasis
    Epidemiology of leishmaniasis in the time of drug resistance (the miltefosine era)
    The role of the immune system in resistance to infection
    Challenges in the diagnosis, treatment and control of leishmaniasis in times of drug resistance
    Co-infection with HIV
    Visceral leishmaniasis
    American tegumentary leishmaniasis
    The challenges of effective leishmaniasis treatment
    Molecular features of drug resistant leishmania
    The role of proteomics in the study of drug resistance
    The role of ABC transporters in drug-resistant leishmania
    Functional analysis of leishmania membrane (non-ABC) transporters involved in drug resistance
    Tools and strategies to circumvent drug resistance in leishmania
    Bioinformatics in leishmania drug design
    P-glycoprotein-like transportyers in leishmania : a search for reversal agents
    The concept of fitness in leishmania.
    Digital Access Springer 2018
  • Digital
    edited by Norbert Handler and Helmut Buschmann.
    Contents:
    Introduction. Polypharmacology in Drug Discovery / Oscar Méndez-Lucio, J Jesús Naveja, Hugo Vite-Caritino, Fernando D Prieto-Martínez, José L Medina-Franco
    Selectivity of Marketed Drugs. Kinase Inhibitors / Peng Wu, Michael Givskov, Thomas E Nielsen
    Repositioning of Drug - New Indications for Marketed Drugs / Ren Kong, Stephen T Wong
    Discovery Technologies for Drug Repurposing / Naiem T Issa, Stephen W Byers, Sivanesan Dakshanamurthy
    Unselective Drugs in Drug Discovery. Personalized Medicine / Christian Noe, Volker Baumann
    Drug Discovery Strategies for the Generation of Multitarget Ligands against Neglected Tropical Diseases / Annachiara Gandini, Federica Prati, Elisa Uliassi, Maria L Bolognesi
    Designing Approaches to Multitarget Drugs / Luca Costantino, Daniela Barlocco
    The Linker Approach / Daniel Merk, Manfred Schubert-Zsilavecz
    Merged Multiple Ligands / Hongming Chen, Udo Bauer, Ola Engkvist
    Pharmacophore Generation for Multiple Ligands / Norbert Handler
    Cellular Assays / Ye Fang
    Therapeutic Areas for Designed Multiple Ligands. Developing Serotonergic Antidepressants Acting on More Than the Serotonin Transporter / Gerard J Marek
    Multiple Ligands Targeting the Angiotensin System for Hypertension / Agustin Casimiro-Garcia
    Multiple Peroxisome Proliferator-Activated Receptor-Based Ligands / Dmytro Kukhtar, Miquel Mulero, Raul Beltrán-Debón, Cristina Valls, Gerard Pujadas, Santiago Garcia-Vallve
    Antibiotics / Jean-Philippe Surivet, Philippe Panchaud
    Multiple Ligands in Neurodegenerative Diseases / Julien Lalut, Christophe Rochais, Patrick Dallemagne.
    Digital Access Wiley 2017
  • Digital
    Summary: "ASHP's Drug Shortages is the most widely recognized leading source of evidence-based drug shortage information for clinicians, consumers, and health policy leaders."
    Digital Access STAT!Ref Current year
    Limited to 2 simultaneous users
  • Digital
    edited by Alexandru Mihai Grumezescu.
    Contents:
    1. Treatment strategies in cancer from past to present
    2. Nanotechnology-based drug delivery systems: challenges and opportunities
    3. Nanotechnology applications in drug controlled release
    4. Target-specific delivery: an insight
    5. Stimuli-responsive nanosystems for drug-targeted delivery
    6. Stimuli sensitive ocular drug delivery systems
    7. Stimuli-sensitive nanomaterials for antimicrobial drug delivery
    8. Stimuli-responsive micelles: a nanoplatform for therpeutic and diagnostic applications
    9. Design of targeting pepetides for nanodrugs for treatment of infectious diseases and cancer
    10. Targeting drugs to cell and organ using nanoparticles
    11. Extracellular vesicles as a recipe for design smart drug delivery systems for cancer therapy
    12. Advancements in exogeneous techniques for stimuli-sensitive delivery systems
    13. Ligand-directed tumor targeting with hybrid viral phage nanoparticles
    14. Delivering miRNA modulators for cancer treatment
    15. Oral controlled and sustained drug delivery systems: concepts, advances, preclinical and clinical status
    16. Hydrogels: from simple networks to smart materials- advances and applications
    17. Recent advances in understanding of blood-brain tumor barrier (BTB) permeability mechanisms that enable better detectino and treatment of brain tumors
    18. Polymeric nanocarriers for site-specific gene therapy
    19. Cyclodextrin-based polymeric nanosystems
    20. Lipid nanoparticles: in vitro and in vivo approaches in drug delivery and targeting
    Index.
    Digital Access ScienceDirect 2018
  • Digital
    Carolina Witchmichen Penteado Schmidt, Fabiana Gatti Menezes.
    Contents:
    1. Introduction
    2. The main diseases in pediatric oncohematology
    3. The main protocols in pediatric oncohematology
    4. Background on drug interactions
    5. Food
    drug interactions
    6. Body surface
    7. Carboplatin dosage calculation
    8. Creatinine clearance estimate.
    Digital Access Springer 2017
  • Print
    Print Access Request
    Location
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    Call Number
    Items
    Stored offsite. Please request print.
    RM260 D794
    4
  • Digital
    Xiaodong Liu, Guoyu Pan, editors.
    Contents:
    Intro; Preface; Contents; Contributors;
    Chapter 1: Overview: Role of Drug Transporters in Drug Disposition and Its Clinical Significance; 1.1 General Consideration; 1.2 Physiological Roles of Drug Transporters; 1.3 Roles of Drug Transporters in Inter-organ Communication; References;
    Chapter 2: ABC Family Transporters; 2.1 Introduction; 2.1.1 General Properties of ABC Transporters; 2.1.2 Overview of Human ABC Gene Subfamilies; 2.1.2.1 ABCA Family; 2.1.2.2 ABCB Family; 2.1.2.3 ABCC Family; 2.1.2.4 ABCD Family; 2.1.2.5 ABCG Family; 2.2 P-Glycoprotein (P-GP/ABCB1) 2.2.1 General Properties and Distribution of P-GP2.2.2 Substrates and Inhibitors of P-GP; 2.2.3 Physiological and Pharmacological Functions of P-GP; 2.2.3.1 Function of P-GP at Blood-Brain Barrier; 2.2.3.2 Function of P-GP at Fetal-Maternal Barrier Function; 2.2.3.3 Function of P-GP at Hepatobiliary Excretion; 2.2.3.4 Function of P-GP in Restricting Oral Bioavailability of Drugs; 2.2.3.5 P-GP Function in the Kidney; 2.2.3.6 P-GP Function in Immune System; 2.2.4 Pharmacological Significance of P-GP Inhibition; 2.2.5 ABCB1 Polymorphisms and P-GP Expression/Function 2.3 Multidrug Resistance-Associated Proteins (MRPs/ABCCs)2.3.1 Multidrug Resistance-Associated Protein 1 (MRP1/ABCC1); 2.3.1.1 General Properties and Distribution of MRP1; 2.3.1.2 Substrates and Inhibitors of MRP1; 2.3.1.3 Pharmacological Functions of MRP1; 2.3.2 Multidrug Resistance Protein 2 (MRP2/ABCC2); 2.3.2.1 General Properties and Distribution of MRP2; 2.3.2.2 Substrates and Inhibitors of MRP2; 2.3.2.3 Pharmacological and Toxicological Functions of MRP2; 2.3.3 Multidrug Resistance Protein 3 (MRP3/ABCC3); 2.3.3.1 General Properties of MRP3 2.3.3.2 Pharmacological and Physiological Functions of MRP32.3.4 Multidrug Resistance Protein 4 (MRP4/ABCC4); 2.3.4.1 General Properties of MRP4; 2.3.4.2 Pharmacological and Physiological Function of MRP4; 2.3.5 Other Multidrug Resistance Proteins; 2.3.5.1 Multidrug Resistance Protein 5 (MRP5); 2.3.5.2 Multidrug Resistance Protein 6 (MRP6/ABCC6); 2.3.5.3 Multidrug Resistance Protein 7 (MRP7/ABCC10); 2.3.5.4 Multidrug Resistance Protein 8 (MRP8/ABCC11); 2.4 Breast Cancer Resistance Protein (BCRP/ABCG2); 2.4.1 General Properties and Distribution of BCRP; 2.4.2 Substrates and Inhibitors of BCRP 2.4.3 Pharmacological and Physiological Functions of BCRP2.4.3.1 Roles of BCRP in Disposition and Toxicity/Efficacy of Drugs; 2.4.3.2 BCRP and Side Population; 2.4.3.3 BCRP and Alzheimerś Disease; 2.4.3.4 BCRP and Hyperuricemia; 2.4.3.5 BCRP and Cancer; 2.5 ABC Genes and Human Genetic Disease; 2.5.1 Cystic Fibrosis and CFTR; 2.5.2 Adrenoleukodystrophy; 2.5.3 Sulfonylurea Receptor; 2.5.4 Bile Salt Transport Disorders; 2.5.5 Retinal Degeneration and ABCA4; 2.5.6 Mitochondrial Iron Homeostasis; 2.5.7 Sterol Transport Deficiencies; References;
    Chapter 3: SLC Family Transporters 3.1 General Introduction
    Digital Access Springer 2019
  • Digital
    editors, Monique Elseviers, Björn Wettermark, Anna Birna Almarsdóttir, Morten Andersen, Ria Benko, Marion Bennie, Irene Eriksson, Brian Godman, Janet Krska, Elisabetta Poluzzi, Katja Taxis, Vera Vlahović-Palčevski, Robert Vander Stichele.
    Digital Access Wiley 2016
  • Digital
    Yasuyuki Kihara, editor.
    Summary: This edited work presents a series of reviews focusing on Druggable Lipid Signaling Pathways. It enables researchers in both academic institutions and industry as well as physicians to understand historical aspects of lipid signaling and future directions of drug discovery targeting lipid signaling pathways. This book provides 9 pathways including acyltransferases, prostanoids, leukotrienes, epoxy fatty acids, sphingolipids, lysophospholipids, endocannabinoids, phosphoinositides, and lipid GPCRs. Readers will discover the importance of each lipid signaling pathway that contributes to broad range of diseases including neurological and neuropsychiatric diseases, pain, metabolic syndromes, cardiovascular diseases, cancer, dermatological diseases, fibrosis, inflammation, etc. Also, readers will recognize that many drugs targeting lipid signaling have been clinically used. Drugs currently under development are also discussed in each chapter, which includes some information about clinical trials and strategic drug designs.

    Contents:
    Preface
    Introduction of Druggable Lipid Signaling Pathway
    Biosynthetic Enzymes of Membrane Glycerophospholipid Diversity as Therapeutic Targets for Drug Development
    Druggable Prostanoid Pathway
    Targeting Leukotrienes as a Therapeutic Strategy to Prevent Comorbidities Associated with Metabolic Stress
    Epoxy Fatty Acids are Promising Targets for Treatment of Pain, Cardiovascular Disease and Other Indications Characterized by Mitochondrial Dysfunction, Endoplasmic Stress and Inflammation
    Druggable Sphingolipid Pathway
    Druggable Lysophospholipid Pathway
    Druggable targets in endocannabinoid signaling
    Drugging the phosphoinositide 3-kinase (PI3K) and phosphatidylinositol 4-kinase (PI4K) family of enzymes for treatment of cancer, immune disorders, and viral/parasitic infections
    Druggable Lipid GPCRs: Past, Present, and Prospects.
    Digital Access Springer 2020
  • Digital/Print
    Prepared for the National Advisory Heart Council by May Sherman.
    Contents: <br/
    >1. Anticholesteremic, anticoagulant, cholesteremic, fibrinolytic, hemoplastic, and vasoactive agents.-
    -2. Cause and cure of hypertension; drugs and the kidney.-
    -3. Cause and cure of heart failure and shock.
    Digital Access
    Provider
    Version
    Google Books
    Google Books
    Google Books
    Google Books
    Print Access Request
    Location
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    Call Number
    Items
    Stored offsite. Please request print.
    U345 .U58 1963
    4
  • Digital
    Muyassar Turaeva.
    Summary: The book outlines post-Soviet style of health management in Central Asia. Regional studies on Central Asia to date have focused on states, politics, religion and inter-ethnic relations but not on the health system within the region. Soviet-style policies have also covered only other aspects relevant for the region. This book highlights the public health situation of the region with a focus on drug abuse, HIV/AIDS in the context of increased mobility, and drug trafficking routes which became even more porous after the break-up of the Soviet Union. Based on a qualitative study, the empirical data in the book was collected during long-term fieldwork conducted in Uzbekistan and Turkmenistan in 2010-2011 as well as shorter stays in Uzbekistan between 2012-2016. The analysis of the empirical material largely draws on the works of Foucault, particularly his concept of biopolitics when analyzing Soviet-style health management that is still practiced in the region. Applying the Foucauldian genealogical method, this study has been structured to trace the genealogy of epidemics to understand the historical path of drug abuse in the region as well as the discursive genealogy of drug politics and drug abuse. Applying the same genealogical method of Foucault, the formative and discursive trajectory of the institution of Uchyot was traced to contextualize the health governance methods that have historical legacy of Soviet-style governance and control of the total population. Drugs and Public Health in Post-Soviet Central Asia: Soviet-Style Health Management is a unique resource for academic specialists, practitioners/professionals, and advanced undergraduate and graduate students in public health, as well as a range of scholars and professionals in sociology, political science, anthropology, and anyone with an interest in the Central Asia region, drug addiction, or HIV. The book also could appeal to international donors in the field of HIV/drug addiction who are working in the region.

    Contents:
    Chapter 1. Introduction
    Chapter 2. Genealogy of Drug Abuse and HIV Infection in Central Asia
    Chapter 3. Biopolitics of Foucault in Post-Soviet Central Asia
    Chapter 4. Individual Concerns of Drug Users and Drug Consumption Patterns Among the Research Participants
    Chapter 5. Socially and Culturally Embedded Drug Abuse
    Chapter 6. HIV-positive Drug Users: Concerns and Problems
    Chapter 7. Lessons Learned and Recommendations
    Index.
    Digital Access Springer 2022
  • Digital
    Telmo Mota Ronzani, editor.
    Summary: This book goes beyond the traditional approaches to drug use and discusses the issue from a societal perspective, integrating contributions from different disciplines such as psychology, public health, anthropology, law, public policies and sociology to address specifically the social aspects of the phenomenon. Given its complexity, drug use demands a multidisciplinary approach from many different perspectives, but despite the vast literature about the topic, the majority of the books are restricted either to a purely medical perspective (focused mainly on treatment techniques) or to a criminological perspective (focused mainly on drug trafficking and organized crime). The social approach adopted in this volume challenges this dichotomy and analyzes both the social contexts to which drug use is related and the social and political consequences of the attitudes and policies adopted by governments and other social groups towards drug users, addressing topics such as: Drugs and poverty Drugs and gender Drugs and race Drugs and territory Stigmatization of drug use Prohibitionism Given its broad and innovative approach, Drugs and Social Context - Social Perspectives on the Use of Alcohol and Other Drugs will be of interest for researchers, clinicians and other health professionals, since the study of the social aspects of drug use is central to everyone who deals with the issue.

    Contents:
    Section 1. Drugs and Society
    Chapter 1.The context of drug use in the consumer society
    Chapter 2. The stigmatization of drug use as mechanism of legitimation of exclusion
    Chapter 3. Social Effects of Prohibitionism in the Americas and New Drug Policies
    Section 2. Social Issues
    Chapter 4.Drugs and Poverty: interfaces of oppression in the capitalist world
    Chapter 5.Drugs and Gender
    Chapter 6. Drugs and Race
    Chapter 7. (Des)Occupation of urban and rural spaces, gentrification and drug use.
    Digital Access Springer 2018
  • Digital
    Bengt Källén.
    Contents:
    Introduction
    The alert clinician
    Animal experiments and adverse drug reaction reports
    Some epidemiological principles
    Pregnancy outcomes with the exception of congenital malformations
    Congenital malformations
    Identification of maternal use of drugs
    The problem of confounding
    Statistics
    Lumping or splitting? Paternal use of drugs
    Timing of drug use and effects on the embryo or fetus
    Repeated studies and meta-analysis
    Pharmacovigilance
    Information on the risk with drug use during pregnancy
    Concluding remarks.
    Digital Access Springer 2016
  • Digital
    Carl P. Weiner, Clifford Mason.
    Summary: "Comprehensive and easy to use, Drugs for Pregnant and Lactating Women, 3rd Edition, remains your #1 resource for reliable information on virtually all of today's drugs and herbal supplements and how they interact with pregnancy and lactation. This logically organized reference has been frequently emulated, but not duplicated. The 3rd Edition has been thoroughly updated to keep you current with new drugs, changes in FDA labeling, and more in-depth information on interactions. Designed for ease of use in the clinical setting, it provides the key drug information needed by physicians, nurses, physician assistants, and others involved in the care of pregnant and lactating women"--Publisher's description.
    Digital Access ClinicalKey 2019
  • Digital
    Gerald G. Briggs, Roger K. Freeman, Craig V. Towers.
    Summary: Put essential information at your fingertips -- before you prescribe. The updated 11th edition of Drugs in Pregnancy and Lactation: A Reference Guide to Fetal and Neonatal Risk lists more than 1,200 commonly prescribed drugs taken during pregnancy and lactation, with detailed monographs that provide the information you need on known or possible effects on the mother, embryo, fetus, and nursing infant. For the 11th edition, this bestselling reference has two new authors, both highly knowledgeable on the effects of drugs on the embryo-fetus and nursing infant: Craig V. Towers, a maternal-fetal medicine specialist, and Alicia B. Forinash, a clinical pharmacologist specialist in obstetrics. -- Provided by publisher.
    Digital Access
    Provider
    Version
    Ovid
    LWW Health Library
  • Digital
    Xavier Bosch, Manuel Ramos-Casals, Munther A. Khamashta, editors.
    Digital Access Springer 2014
  • Digital
    Colin Chan, editor.
    Summary: This handbook is a concise, easy-to-read, practical guide that conveys the core knowledge necessary to diagnose, classify, grade, and manage dry eye disease effectively and efficiently. A series of succinct, informative chapters cover the following key topics: definition and classification, epidemiology, office-based screening and diagnostics, artificial tears, medical management, surgical management, and future directions. Current guidelines, published studies, and the personal experience of internationally recognized dry eye experts are distilled into practical tips that will be of value during daily clinical routine. Highlighted boxes are included to emphasize the most important points or clinical pearls, and tables and flow charts will further assist the eye care practitioner in using the book as a quick reference. The closing chapter presents case examples that build upon the instruction provided earlier in the book by illustrating the optimal approach to diverse scenarios that may be encountered in the clinic.

    Contents:
    Introduction
    Definition and classification of dry eye
    Epidemiology of dry eye
    How to choose the right artificial tear
    Practical office based screening and diagnostics
    Medical management of dry eye
    Procedural / surgical management of dry eye
    Case studies
    Future directions and research.
    Digital Access Springer 2015
  • Digital
    Paolo D'Odorico, Amilcare Porporato, Christiane Wilkinson Runyan, editors.
    Summary: By combining the analysis of biotic and abiotic components of terrestrial ecosystems, this book synthesizes material on arid and semiarid landscapes, which was previously scattered among various books and journal articles. It focuses on water-limited ecosystems, which are highly sensitive to fluctuations in hydrologic conditions and, in turn, play an important role in affecting the regional water cycle. Intended as a tool for scientists working in the area of the earth and environmental sciences, this book presents the basic principles of eco-hydrology as well as a broad spectrum of topics and advances in this research field. Written by authors with diverse areas of expertise who work in arid areas around the world, the contributions describe the various interactions between the biological and physical dynamics in dryland ecosystems, ranging from basic processes in the soil-vegetation-climate system, to landscape-scale hydrologic and geomorphic processes, ecohydrologic controls on soil nutrient dynamics, and multiscale analyses of disturbances and patterns.

    Contents:
    Chapter 1. Introduction
    SECTION 1: FUNDAMENTAL PROCESSES AND INTERACTIONS IN THE SOIL-CLIMATE-VEGETATION SYSTEM
    Chapter 2. Soil Moisture Dynamics in Water-Limited Ecosystems
    Chapter3. Soil physical properties and associated soil-root interactions
    Chapter 4. Ecophysiology of plants in dry environments
    Chapter 5. Ecohydrology of Photosynthesis
    Chapter 6. Ecohydrological controls on the deposition of non-rainfall water, N and P to dryland ecosystems
    Interactions and feedbacks between climate and dryland vegetations
    SECTION 2: HYDROGEOMORPHOLOGY AND LANDFORMS OF ARID AND SEMIARID LANDSCAPES
    Chapter 8. The history and evolution of desert hydrology and landforms: The role of climate change
    Chapter 9. Ecohydrological implications of aeolian processes in drylands
    Chapter 10. Hydrological and geomorphological significance of riparian vegetation in drylands
    SECTION 3: ECOHYDROLOGIC CONTROLS on NUTRIENT CYCLING and DISTURBANCES
    Chapter 11. Ecohydrological and stoichiometric controls on soil carbon and nitrogen dynamics in drylands
    Chapter 12. Modeling of Phosphorus Dynamics in Dryland Ecosystems
    Chapter 13. Microbial nitric oxide, nitrous oxide and nitrous acid emissions from drylands
    Chapter 14. Fire regimes in dryland landscapes
    Chapter 15. Termites as mediators of the water economy of arid savanna ecosystems
    SECTION 4: ECOHYDROLOGY OF A VARIETY OF DRYLAND ECOSYSTEMS
    Chapter 16. Interactions of water and nitrogen on primary productivity across spatial and temporal scales in grassland and shrubland ecosystems
    Chapter 17. Deforestation, water availability, and nutrient cycling in dry forests
    Chapter 18. Vegetation pattern formation in drylands
    Chapter 19. Ecohydrology of agroecosystems
    Interactions between local and global processes
    Chapter 20. Ecohydrology of urban ecosystems
    Chapter 21. Desertification and land degradation.
    Digital Access Springer 2019
  • Digital
    edited by Roberto Lewis-Fernández, Neil Krishan Aggarwal, Ladson Hinton, Devon E. Hinton, Laurence J. Kirmayer.
    Contents:
    Machine generated contents note: 1. Cultural Formulation Before DSM-5 / Laurence J. Kirmayer
    2. The Core and Informant Cultural Formulation Interviews in DSM-5 / Roberto Lewis-Fernandez
    3. Supplementary Modules
    Overview / Ladson Hinton
    Supplementary Module 1 Explanatory Model / Mitchell G. Weiss
    Supplementary Module 2 Level of Functioning / Sofie Baarnhielm
    Supplementary Module 3 Social Network / Ladson Hinton
    Supplementary Module 4 Psychosocial Stressors / Ladson Hinton
    Supplementary Module 5 Spirituality, Religion, and Moral Traditions / Francis G. Lu
    Supplementary Module 6 Cultural Identity / Neil Krishan Aggarwal
    Aspects of Cultural Identity Related to National, Ethnic, and Racial Background; Language; and Migration / Sushrut Jadhav
    Aspects of Cultural Identity Related to Spirituality, Religion, and Moral Traditions / Francis G. Lu
    Aspects of Cultural Identity Related to Gender Identity and Sexual Orientation Identity / Mark L. Hatzenbuehler
    Supplementary Module 7 Coping and Help Seeking / Devon E. Hinton
    Supplementary Module 8 Patient-Clinician Relationship / Sofie Baarnhielm
    Supplementary Module 9 School-Age Children and Adolescents / Jaswant Guzder
    Supplementary Module 10 Older Adults / Ladson Hinton
    Supplementary Module 11 Immigrants and Refugees / Monica Scalco
    Supplementary Module 12 Caregivers / Iqbal Ahmed
    4. Clinical Implementation of the Cultural Formulation Interview
    Planning and Assessment / Neil Krishan Aggarwal
    Use of the Cultural Formulation Interview in Different Clinical Settings / Lizardo Cruzado
    Administrative Perspectives on the Implementation and Use of the Cultural Formulation Interview / Angela Tang Soriano
    Application of the Cultural Formulation Interview in International Settings / Smita Neelkanth Deshpande
    5. Cultural Competence in Psychiatric Education Using the Cultural Formulation Interview / Hendry Ton
    6. Conclusion: The Future of Cultural Formulation / Laurence J. Kirmayer.
    Digital Access PsychiatryOnline 2016
  • Digital
    Sophia Wang, M.D., Abraham M. Nussbaum, M.D., FAPA.
    Contents:
    Addressing behavioral and mental problems in community settings
    The diagnostic DS : the building blocks to diagnosing mental health disorders in older adults
    Beyond the diagnostic DS : other common clinical challenges
    The 15-minute older adult diagnostic interview
    The 30-minute older adult diagnostic interview
    The DSM-5 older adult diagnostic interview
    A brief version of DSM-5
    A stepwise approach to differential diagnosis
    The mental status examination : a psychiatric glossary
    Selected DSM-5 assessment measures
    Rating scales and alternative diagnostic systems
    Psychoeducational interventions
    Psychosocial interventions
    Psychotherapeutic interventions
    Psychopharmacological interventions
    Brain stimulation interventions
    Mental health treatment planning
    Concluding counsel.
    Digital Access PsychiatryOnline 2017
  • Digital/Print
    edited by John W. Barnhill.
    Contents:
    Neurodevelopmental disorders
    Schizophrenia spectrum and other psychotic disorders
    Bipolar and related disorders
    Depressive disorders
    Anxiety disorders
    Obsessive-compulsive and related disorders
    Trauma- and stressor-related disorders
    Dissociative disorders
    Somatic symptom and related disorders
    Feeding and eating disorders
    Elimination disorders
    Sleep-wake disorders
    Sexual dysfunctions
    Gender dysphoria
    Disruptive, impulse-control, and conduct disorders
    Substance-related and addictive disorders
    Neurocognitive disorders
    Personality disorders
    Paraphilic disorders.
    Digital Access PsychiatryOnline 2014
    Print Access Request
    Location
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    Call Number
    Items
    Books: General Collection (Downstairs)
    RC473.D54 D76 2014
    1
  • Digital/Print
    Michael B. First.
    Contents:
    Part I. Differential diagnosis step by step
    Part II. Differential diagnosis by the trees
    Part III. Differential diagnosis by the tables
    Neurodevelopmental disorders
    Schizophrenia spectrum and other psychotic disorders
    Bipolar and related disorders
    Depressive disorders
    Anxiety disorders
    Obsessive-compulsive and related disorders
    Trauma- and Stressor-related disorders
    Dissociative disorders
    Somatic symptom and related disorders
    Feeding and eating disorders
    Sleep-wake disorders
    Sexual dysfunctions
    Gender dysphoria
    Disruptive, impulse-control, and conduct disorders
    Substance-related and addictive disorders
    Neurocognitive disorders
    Personality disorders
    Paraphilic disorders.
    Digital Access PsychiatryOnline 2014
    Print
    Location
    Version
    Call Number
    Items
    Reference (Upstairs)
    RC473.D54 F554 2014
    1
  • Digital
    by Robert J. Hilt, Abraham M. Nussbaum.
    Contents:
    Addressing behavioral and mental problems in community settings
    Common clinical concerns
    The 15-minute pediatric diagnostic interview
    The 30-minute pediatric diagnostic interview
    DSM-5 pediatric interview
    A brief version of DSM-5
    A stepwise approach to differential diagnosis
    The mental state examination : a psychiatric glossary
    Selected DSM-5 assessment measures
    Rating scales and alternative diagnostic systems
    Developmental milestones
    Mental health treatment planning
    Psychosocial interventions
    Psychotherapeutic interventions
    Psychopharmacology
    Ideas for practice, education, and research.
    Digital Access PsychiatryOnline 2016
  • Digital
    edited by John W. Barnhill.
    Summary: "DSM-5-TR Clinical Cases clarifies and discusses psychiatric diagnosis with a particular focus on how diagnoses have evolved from DSM-5. Designed for teachers, students, and clinicians, this book presents a broad range of patient vignettes that cover the diagnostic waterfront. Each of the 104 cases is followed by a discussion by an expert clinician, who describes an approach to diagnosis through an exploration of psychiatric and personal history, symptom clusters, laboratory tests, and clinical ambiguities. The discussants also address the important ways in which diagnosis might be affected by such demographic issues as ethnicity, sexual orientation, and gender identity. Anyone interested in understanding the interface between disorder classification and patient diagnosis will find DSM-5-TR Clinical Cases compelling, captivating, and enlightening"-- Provided by publisher.

    Contents:
    Neurodevelopmental Disorders
    Schizophrenia Spectrum and Other Psychotic Disorders
    Bipolar and Related Disorders
    Depressive Disorders
    Anxiety Disorders
    Obsessive-Compulsive and Related Disorders
    Trauma- and Stressor-Related Disorders
    Dissociative Disorders
    Somatic Symptom and Related Disorders
    Feeding and Eating Disorders
    Elimination Disorders
    Sleep-Wake Disorders
    Sexual Dysfunctions
    Gender Dysphoria
    Disruptive, Impulse-Control, and Conduct Disorders
    Substance-Related and Addictive Disorders
    Neurocognitive Disorders
    Personality Disorders
    Paraphilic Disorders.
    Digital Access PsychiatryOnline 2023
  • Print
    edited by Thomas A. Widiger ... [et al.].
    Print Access Request
    Location
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    Books: General Collection (Downstairs)
    RC455.2.C4 D754
    3
  • Digital
    Patricia M. Carrascosa, Ricardo C. Cury, Mario J. García, Jonathon A. Leipsic, editors.
    Summary: This book focuses on the rapidly developing and promising novel applications of Dual Energy CT (DECT) in cardiovascular medicine. Although developed many years ago, DECT represents the newest significant advancement in the field of computed tomography, the clinical utility of which has recently expanded as many new applications have been developed. In the field of cardiovascular medicine, DECT has been applied for purposes such as the evaluation of myocardial ischemia, myocardial viability and atherosclerotic plaque characterization. As the first book of its kind, Dual-Energy CT in Cardiovascular Imaging contains practical and clinically relevant information on the protocols used that provide precise quantification of coronary artery stenosis using either different monochromatic levels or material decomposition, reduction of beam hardening artifacts in perfusion studies and optimizing endovenous contrast, among others. It is therefore a valuable read for residents, fellows and practicing clinicians in cardiac imaging and cardiology.

    Contents:
    Introduction to DECT
    Technical aspects of DECT with dual source
    Technical aspects of DECT with dual layer
    Gemstone Imaging
    Neurovascular Imaging
    Neck imaging
    Thoracic imaging
    Abdominal imaging
    Upper and lower limbs imaging
    Technical Advancements for Cardiac Imaging
    Plaque characterization
    Accuracy of DECT in coronary arteries
    Beam Hardening Reduction and Image Quality Improvements with DECT
    Myocardial CT perfusion
    Myocardial viability
    Pitfalls
    Limitations
    Management of radiation
    Future.
    Digital Access Springer 2015
  • Digital
    Carlo N. De Cecco, Andrea Laghi, U. Joseph Schoepf, Felix G. Meinel, editors.
    Summary: The aim of this book is fourfold: to describe the basic principles of Dual Energy CT (DECT) imaging, to explain how post-processing is utilized, to critically appraise the strengths and weaknesses of the technique in oncologic imaging, and above all, to demonstrate the contribution of DECT in the management of oncologic patients. Information is provided on the practice and interpretation of DECT and its impact on clinical decision making in a variety of oncological settings, including tumors of the head and neck, lung, liver, pancreas, gastrointestinal system, kidney, and musculoskeletal system. DECT is an innovative imaging technique in which the application of two distinct energy settings provides a transition from density-based image to spectral imaging. As detailed in this book, DECT acquisition allows the simultaneous generation of multiple datasets which enable the radiologist to address varied diagnostic problems in oncologic imaging using a multiparametric approach, having clear advantages in tumor detection, lesion characterization and evaluation of treatment response.

    Contents:
    Dual Energy CT: Basic Principles
    Dual Energy CT: Post-Processing and Image Analysis Strategies in Oncologic Imaging
    Dual Energy CT of Head and Neck Tumors
    Dual Energy CT of Lung Tumors
    Dual Energy CT of Liver Tumors
    Dual Energy CT of Pancreatic Tumors
    Dual Energy CT of Gastrointestinal Tumors
    Dual Energy CT of Genitourinary Tumors
    Dual Energy CT of Musculoskeletal Tumors.
    Digital Access Springer 2015
  • Digital
    editors, Daniel J. Wallace, Bevra Hannahs Hahn ; associate editors, Mary K. Crow [and five others].
    Summary: "For more than 50 years, Dubois’ Lupus Erythematosus and Related Syndromes has been recognized internationally as the go-to clinical reference on lupus and other connective tissue diseases. From basic scientific principles to practical points of clinical management, the updated 9th Edition provides extensive, authoritative coverage of systemic lupus erythematosus (SLE) and its related diseases in a logical, clearly written, user-friendly manner. It’s an ideal resource for rheumatologists and internal medicine practitioners who need a comprehensive clinical reference on all aspects of SLE, connective tissue diseases, and the antiphospholipid syndromes"--Publisher's description.

    Contents:
    History of lupus
    Definition and classification of lupus and lupus-related disorders
    The epidemiology of lupus
    Overview of lupus pathogenesis
    Genetics of human SLE
    Epigenetics of lupus
    The environment and the host
    The innate immune system in SLE
    B cells and generation of antibodies
    T cells
    Adaptive and innate immunoregulatory cells
    Cytokines in lupus
    Immunometabolism
    Animal models in lupus
    Abnormalities in immune complex clearance and apoptotic cell clearance
    The role of complement in SLE
    Apoptosis and inflammatory forms of cell death
    Tissue damage in lupus : free radicals and fibrosis
    Pathogenesis of fibrosis—the lung as a model
    Pathogenesis of lupus nephritis
    Pathogenesis of accelerated atherosclerosis and vascular injury in systemic lupus erythematosus
    Pathogenesis of cutaneous lupus
    Pathogenesis of neuropsychiatric lupus
    Pathogenesis of antiphospholipid antibody syndrome
    Pathogenesis of Sjögren's
    Structure and derivation of autoantibodies
    Antinuclear antibodies, antibodies to DNA, histones, and nucleosomes
    Antibodies against ENA (SM, RNP, SSA, SSB)
    Antibodies against C1q
    Antilipoprotein and antiendothelial cell antibodies
    Drug-induced lupus erythematosus
    Overview and clinical presentation
    Skin disease in cutaneous lupus erythematosus
    The musculoskeletal system and bone metabolism
    Lupus and the cardiopulmonary system
    Lupus and the nervous system : clinical aspects, psychopathology, and imaging
    Gastrointestinal and hepatic systems
    Hematologic and lymphoid abnormalities in SLE
    Neonatal lupus : pathogenesis and clinical approaches
    Pregnancy and autoimmune disease, reproductive and hormonal issues
    Systemic lupus erythematosus in childhood and adolescence
    Clinical aspects of antiphospholipid syndrome
    Lupus and infections
    Ocular, aural, and oral manifestations of lupus
    Clinical aspects of Sjögren's
    Clinical application of serologic tests, serum protein abnormalities, and other clinical laboratory tests in systemic lupus erythematosus
    Differential diagnosis and disease associations
    Incomplete lupus, undifferentiated connective tissue disease, and mixed connective tissue disease
    Clinical markers, metrics, indices, and clinical trials
    Lupus biomarkers
    Principles of therapy, local measures, and NSAIDs
    Antimalarial medications
    Systemic glucocorticoid therapy for SLE
    Immunosuppressive drug therapy
    Complementary and alternative medications, specialized and niche therapies
    Adjunctive treatments and preventive measures
    Targeted therapies in SLE
    Management of cutaneous lupus erythematosus
    Epidemiology and management of lupus nephritis
    Management of Sjögren's
    Socioeconomic and disability aspects
    Prognosis and mortality of SLE.
    Digital Access ClinicalKey 2019
  • Digital
    Xuan Hieu Cao, Paul Fourounjian, Wenqin Wang, editors.
    Summary: This book tells the story behind the first Spirodela genome sequencing project. Further, it describes the current genomics applications of these findings, and efforts to sequence new genomes within the family. The closing chapters address the sequencing of the over 1 Gigabase Wolffia genomes, which could have major impacts on genome evolution and agricultural research. The duckweed or Lemnaceae family is a collection of 5 genera and 37 species of the smallest, fastest-growing flowering plants. Many of these aquatic monocotyledonous plants can grow all over the world, in a variety of climates. Given their simplified and neotenous morphology, duckweeds have been researched for several decades as a model species for plant physiology and ecotoxicological research, contributing to our understanding e.g. of flowering response, plant circadian systems, sulfur assimilation pathways and auxin biosynthesis. In addition, duckweed-based treatment has been a favorite and feasible means, especially in developing countries, of removing phosphorus and pharmaceutical chemicals from sewage and wastewater. With a dry annual mass yield per hectare of up to 80 tonnes (equivalent to 10 tonnes of protein), duckweed is also a promising aquatic crop in new modern and sustainable agriculture. Besides being an excellent primary or supplemental feedstock for the production of livestock and fish, duckweed biomass can be utilized as a potential resource for human nutrition, biofuel, or bioplastics, depending on water quality as well as protein or starch accumulating procedures. These academic and commercial interests have led to international efforts to sequence the Spirodela polyrhiza genome, the smallest and most ancient genome in the family.

    Contents:
    Importance of duckweeds in basic research and its industrial applications
    Background history of the international Spirodela genome sequencing initiatives
    Cytogenetics and karyotype evolution of duckweeds
    Duckweed organelle genomes
    Repetitive sequences: Impacts and uses in the Spirodela genome
    Genotyping by sequencing of duckweeds
    Genome and transcriptome of Landoltia punctata
    Transcriptome responses of Spirodela polyrhiza
    Strategies & tools for sequencing duckweeds
    Transformation development in duckweeds.
    Digital Access Springer 2020
  • Digital
    Lisa A. Newman, Jessica M. Bensenhaver, editors.
    Summary: This volume reviews the evolution of information regarding the epidemiology of DCIS and its modes of detection, as well as treatment options as a function of both clinical trial data and ongoing investigational therapeutic prospects. Several of the challenging and clinically-relevant scenarios of DCIS that appear in daily practice is discussed, including the difficulties of distinguishing "true" DCIS from borderline patterns of other breast diseases and the therapeutic implications of differentiating these various diagnoses. Particular attention is paid to pathologic evaluation of DCIS, including histologic patterns and the importance of margin evaluation/margin control. The text also explores the data regarding DCIS in medical research in hereditary susceptibility for breast cancer and race/ethnicity-associated disparities in breast cancer. Written by experts in the field, Ductal Carcinoma In Situ and Microinvasive/Borderline Breast Cancer is a comprehensive, state-of-the art review of the field, and serves as a valuable resource for clinicians, surgeons and researchers with an interest in breast cancer.

    Contents:
    Epidemiology of Ductal Carcinoma In Situ
    Role of Screening Mammography in Early Detection/Outcome from Breast Cancer
    Imaging DCIS: Digital/Film Screening Mammography, Tomosynthesis, MRI, Ultrasonography
    Pathology of Ductal Carcinoma In Situ: Features and Diagnostic Challenges
    Molecular Markers in DCIS
    History of Ductal Carcinoma In Situ Management Based Upon Data from Prospective, Randomized Clinical Trials
    Extent and Role of Margin Control for DCIS Managed by Breast-Conserving Surgery
    Ductal Carcinoma In Situ Treated With Breast Conserving Surgery Alone
    DCIS Managed with BCS: Whole-Breast XRT vs. Partial Breast XRT
    Anti-HER2/neu Therapy in DCIS
    Role of Genetic Profiling and Recurrence Scores in Treatment Planning for DCIS
    DCIS and Sentinel Lymph Node Biopsy
    Role of Postmastectomy Radiation for DCIS
    Monitoring and Surveillance Following DCIS Treatment
    DCIS and Hereditary Susceptibility for Breast Cancer
    Introduction, Evolution and Application of the Van Nuys Prognostic Index in DCIS
    Disparities in DCIS Detection and Outcomes Related to Race/Ethnicity.
    Digital Access Springer 2015
  • Digital
    Jeffrey R. Marcus, Anna R. Carlson.
    Summary: Contains 27 videos and 36 illustrations with extensive accompanying text.
  • Digital
    [edited by] Preeya K. Gupta, Nandini Venkateswaran.
    Summary: "Concise, authoritative, and easy to navigate, The Duke Manual of Corneal and Cataract Surgery offers a step-by-step, highly illustrated approach to the most commonly performed procedures in corneal and cataract surgery. Ideal for cornea and cataract specialists, ophthalmic surgeons, residents, and fellows, it contains practical guidance from Drs. Nandini Venkateswaran and Preeya K. Gupta, as well as other experts at Duke University, making it an unparalleled "how-to" manual for the wide variety of cases and operative scenarios you may encounter. Offers a step-by-step outline for each surgical procedure, from preoperative considerations through postoperative care, including numerous surgical pearls. Contains dozen of full-color photographs and illustrations that clearly depict techniques and other essential aspects of corneal and cataract surgery. Covers surgery basics, gas and liquid surgical aides, pediatrics, and management of challenging surgical scenarios"-- Provided by publisher.
    Digital Access LWW Health Library 2022
  • Digital
    [edited by] Divakar Gupta, Leon W. Herndon, Jr., Kelly W. Muir.
    Summary: "Concise, authoritative, and easy to navigate, The Duke Manual of Glaucoma Surgery offers a step-by-step, highly illustrated approach to the most commonly performed glaucoma surgeries and procedures. Ideal for glaucoma specialists, ophthalmic surgeons, residents, and fellows, it contains practical guidance from Drs. Divakar Gupta, Leon Herndon, Kelly Muir, as well as other experts at Duke University, making it an unparalleled "how-to" manual for the wide variety of cases and operative scenarios you may encounter. Offers a step-by-step outline for each surgical procedure, from preoperative considerations through postoperative care, including numerous surgical pearls. Contains 200 full-color photographs and illustrations that clearly depict techniques and other essential aspects of glaucoma surgery. Covers surgery basics, pediatrics, and management of challenging surgical scenarios. Provides access, via the eBook, to surgical videos from the Duke archive"--Publisher's description.

    Contents:
    Section 1: Just the basics. Preoperative discussion
    Setting up for surgery
    Section 2: Trabeculectomy. Preoperative considerations for trabeculectomy
    Different ways to administer antimetabolites
    Limbal versus fornix conjunctival flap
    Steps of a trabeculectomy
    Scleral flap and sclerostomy construction
    Ex-press shunt implantation with mitomycin C
    Releasable sutures
    Conjunctival closures
    Postoperative medications and manipulations for trabeculectomy
    Section 3: Tube shunts. Preoperative planning and considerations for tube shunts
    Types of shunts, tube ligation, patch materials
    Ahmed valved tube shunt
    Nonvalved tube shunt
    Tube placement locations
    Special cases: neovascular and uveitic glaucoma
    Special cases: prior scleral buckle
    Postoperative medications and manipulations for tube shunts
    Section 4: Angle-based surgery. Preoperative considerations for angle-based surgery
    Intraoperative gonioscopy
    Trabecular meshwork stents
    Ab interno trabeculotomy: trabectome
    Goniotomy with the Kahook dual blade
    Ab interno trabeculotomy and viscocanaloplasty
    Goniosynechialysis
    Postoperative medications and considerations for angle-based surgery
    Section 5: Subconjunctival bypass. Preoperative considerations for xen implantation
    Xen ab interno implantation
    Xen ab externo implantation
    Postoperative considerations for xen implantation
    Section 6: Cycloblative laser. Preoperative planning and considerations for cyclophotocoagulation
    Endocyclophotocoagulation
    Transscleral diode cyclophotocoagulation
    Micropulse cyclophotocoagulation
    Section 7: Cataract and lens surgery in the glaucoma patient. Preoperative planning for cataract and lens surgery in the glaucoma patient
    Considerations for combined cataract and glaucoma surgery
    Special cases: angle closure
    Special cases: nanophthalmos
    Special cases: exfoliation syndrome
    Clinical evaluation and surgical management of subluxed and dislocated intraocular lens implant
    Secondary Iol placement: sulcus, sutured, aciol
    Section 8: Trabeculectomy revisions. Preoperative considerations for trabeculectomy revisions
    Excision and pull down
    Conjunctival autograft
    Transconjunctival suturing
    Bleb compression sutures
    Revisions for bleb dysesthesia
    Section 9: Tube shunt revisions. Preoperative planning and considerations for tube shunt revisions
    Tube shunt revision for exposure
    Tube shunt repositioning
    Tube extender
    Tube shunt revision for hypotony
    Section 10: Challenging surgical cases. Management of intraoperative malignant glaucoma
    Management of hemorrhagic choroidals
    Scleral windows in nanophthalmos
    Drainage of serous choroidals
    Cyclodialysis cleft repair
    Section 11: Clinic lasers. Selective laser trabeculoplasty
    Peripheral iridotomy
    Iridoplasty.
    Digital Access LWW Health Library 2022
  • Digital
    Michael Richard, Jason Liss, Nicholas Ramey.
    Digital Access LWW Health Library 2021
  • Digital
    Laura B. Enyedi, MD, Nandini Gandhi, MD, Tammy L. Yanovitch, MD, MHSc.
    Digital Access LWW Health Library 2021
  • Digital
    [edited by] Sharon Fekrat ; associate editors Avni Patel Finn, Akshay S. Thomas ; illustrations by Xi Chen.
    Summary: "Concise, authoritative, and easy to navigate, The Duke Manual of Vitreoretinal Surgery offers a step-by-step, highly illustrated approach to the most commonly performed vitreoretinal operating room procedures. Ideal for vitreoretinal surgeons, ophthalmology residents, retina fellows, and OR nurses and scrub techs, it contains practical guidance from the highly esteemed vitreoretinal surgery fellowship program at Duke University making it an unparalleled “how-to” manual for the wide variety of cases and operative scenarios you may encounter"-- Provided by publisher.

    Contents:
    Section I. Just the basics
    section II. Pars plana vitrectomy
    section III. Vitreoretinal surgical adjuncts
    section IV. Exchanges
    section V. Rhegmatogenous retinal detachment
    section VI. Macular surgery
    section VII. Lensectomy and secondary iol placement
    section VIII. Diabetic vitrectomy
    section IX. Pediatric vitreoretinal surgery
    section X. Vitreoretinal surgery for tumors and uveitis
    section XI. Challenging vitreoretinal surgical scenarios.
    Digital Access
    Provider
    Version
    Ovid
    LWW Health Library
  • Digital
    edited by Mina K. Dulcan.
    Summary: "Dulcan's Textbook of Child and Adolescent Psychiatry provides in-depth, DSM-5-aligned evidence-based clinical guidance in such areas as neurodevelopmental and other psychiatric disorders; psychosocial treatments; pediatric psychopharmacology; and special topics, including cultural considerations, youth suicide, legal and ethical issues, and gender and sexual diversity. This third edition includes expanded information on telehealth, e-mental health, and pediatric consultation-liaison psychiatry"-- Provided by publisher.
    Digital Access PsychiatryOnline 2022
  • Digital
    Bernhard Widder, Gerhard F. Hamann, editors.
    Digital Access Springer 2022
  • Digital
    Erika Mendoza, Christopher R. Lattimer, Nick Morrison, editors.
    Summary: This book describes in detail the use of duplex ultrasound for exploration of the superficial veins and their pathology. It has a practical orientation, presenting numerous clinical situations and explaining how to identify the different sources of reflux, specially in the groin. The investigation of pathology of the saphenous trunks, perforators, and side branches is described in detail. As duplex ultrasound plays an important role during various venous surgical procedures, its application pre-, intra-, and postoperatively is presented. Furthermore, the sonographic appearances of thrombotic pathology of superficial and deep veins, edema, and other conditions that may be observed while exploring the veins are fully described. The book is based on the authors{u2019} extensive clinical experience and is intended to assist fellow practitioners who want to learn more about the technique. It includes a wealth of informative images with the aim of covering every potential situation.

    Contents:
    The Ultrasound Scanner
    Anatomy of the Superficial Veins
    Pathophysiology of the Superficial Venous System
    Ultrasound-Based Classifications of Varicose Veins
    Duplex Ultrasound Examination of Superficial Leg Veins
    Flow Provocation Manoeuvres for the Diagnosis of Venous Disease Using Duplex Ultrasound
    Examination of the Great Saphenous Vein
    Examination of the Small Saphenous Vein
    Perforating Veins
    Tributaries
    Superficial Vein Thrombosis
    Ultrasound in Varicose Vein Treatment
    Ultrasound After Venous Intervention
    Deep Leg Veins
    Examination of Superficial Veins in the Presence of Deep Venous Disease
    Differential Diagnosis of Leg Oedemas of Venous and Lymphatic Origin
    Incidental Findings During a Venous Examination of the Leg.
    Digital Access Springer 2014
  • Digital
    Paul M. N. Werker, Joseph Dias, Charles Eaton, Bert Reichert, Wolfgang Wach, editors.
    Contents:
    Epidemiology and Patients Views
    Cellular and Extra-cellular Events
    Genetics and Associations
    Collagenase Injection
    Percutaneous Needle Fasciotomy (PNF)
    Assessment
    Comparative Studies
    Surgical Techniques and Recurrence
    Related Diseases and Other Treatments
    Future Paths of Research.
    Digital Access Springer 2017
  • Digital
    Marco Rizzo, editor.
    Contents:
    1. Nonoperative management of finger flexion contracture in Dupuytren's disease: orthotic intervention and tissue mobilization techniques
    2. Needle aponeurotomy in the management of Dupuytren's contracture
    3. Ultrasound assisted needle aponeurotomy in the management of Dupuytren's contracture
    4. Corticosteroid injections and needle aponeurotomy in the management of Dupuytren's contracture
    5. Clostridial collagenase injections in the treatment of Dupuytren's contracture
    6. Minimally invasive partial fasciectomy
    7. Surgical fasciotomy for Dupuytren's contracture
    8. Surgical fasciectomy for Dupuytren's contracture
    9. Wide awake Dupuytren's fasciectomy: a pathoanatomical approach
    10. .Surgical open palm (McCash) technique
    11. Treatment of Dupuytren's contracture with dermofasciectomy
    12. Surgical fasciectomy for recurrent disease
    13. Use of dynamic external fixator (digit widget) in Dupuytren's contracture
    14. The distal interphalangeal joint in Dupuytren's disease
    15. Knuckle pads (Garrod's nodules) of the fingers: painful dorsal nodules on the PIP joints of the fingers and concomitant recurrent Dupuytren's contracture
    16. Arthrodesis in treatment of Dupuytren contracture
    17. Amputation in management of severe Dupuytren's contracture
    18. Treatment of Dupuytren's contracture in the young
    19. Recurrent Dupuytren contracture treated with fasciectomy and skin grafting
    Index.
    Digital Access Springer 2016
  • Digital
    Stuart Silverman, Bo Abrahamsen, editors.
    Contents:
    Foreword
    Preface
    Osteoporosis: Pathophysiology & Epidemiology
    Antiresorptives
    Anabolics
    Tools for Assessing Fracture Risk and for Treatment Monitoring
    Treatment Failure
    Epidemiology of Atypical Subtrochanteric and Femoral Shaft Fractures
    Bisphosphonate-Related Atypical Femoral Fractures and Their Radiographic Features
    Factors Contributing to Atypical Femoral Fractures
    Clinical Presentation of Atypical Femur Fractures
    Effects of Antiresorptive Therapy on Bone Microarchitecture
    Management of Atypical Femoral Fractures
    Osteonecrosis of the Jaw: Clinico-Pathologic and Radiologic Features
    Epidemiology of Osteonecrosis of the Jaws from Antiresorptive Treatment
    Management of Osteonecrosis of the Jaw in Patients Receiving Antiresorptive Treatment
    Long-Term Efficacy and Safety of Treatments for Osteoporosis
    Management of Drug Holidays
    Patients Who Do Not Take Their Osteoporosis Medications: Can We Help Them Become Compliant?
    Fractures and Healing on Antiresorptive Therapy
    Antiresorptive Therapy and Mortality and Cancer Incidence
    Other Safety Concerns
    The Impact of Regulatory and Scientific Organizations Recommendations on Clinical Decision Making
    Integrated Clinical View on Long-Term Management of Patients with Osteoporosis
    Conclusions.
    Digital Access Springer 2016
  • Digital
    Mark Dutton.
    Summary: This book introduces a conceptual framework about the art of physical therapy to give the entry-level physical therapy student a broad foundation from which to support their journey through the typical physical therapy curriculum. The purpose of this text is to cover the fundamental skills that most physical therapists will use for the rest of their careers.

    Contents:
    Chapter 1: The Profession
    Chapter 2: Healthcare Regulations
    Chapter 3: Evidence-Informed Practice
    Chapter 4: Foundations of Movement
    Chapter 5: Patient/Client Management
    Chapter 6: Movement Dysfunction
    Chapter 7: Correcting Movement Dysfunction
    Chapter 8: Preparation for Patient Care
    Chapter 9: Monitoring Vital Signs
    Chapter 10: Bed Mobility, Patient Positioning, and Draping
    Chapter 11: Mobility
    Chapter 12: Manual Muscle Testing
    Chapter 13: Patient Transfers and Mobility
    Chapter 14: Gait Training
    Appendix A: Standards of Practice for Physical Therapy
    Appendix B: Criteria for Standards of Practice for Physical Therapy
    Appendix C: Code of Ethics
    Appendix D: Standards of Ethical Conduct for the Physical Therapist Assistant
    Appendix E: American Physical Therapy Association (APTA).
    Digital Access AccessPhysiotherapy 2021
  • Digital
    Mark Dutton, PT.
    Summary: "This book introduces a conceptual framework about the art of physical therapy to give the entry-level physical therapist assistant (PTA) student a broad foundation from which to support their journey through a typical curriculum. The purpose of this text is to cover the fundamental skills that most PTAs will use for the rest of their careers. This text provides a historical perspective on the physical therapy profession, an introduction to healthcare policy, and a definition of evidence-informed practice, and various chapters describing specific areas of clinical expertise, including how to enhance a patient's function in such tasks as bed mobility, transfers, and gait training. Chapter 1 provides a historical perspective on the physical therapy profession. Chapter 2 introduces the reader to essential healthcare policies. Chapter 3 describes the importance of evidence-informed practice and clinical decision-making. Chapter 4 outlines clinical documentation. With every patient interaction, the clinician should always ensure patient and clinician safety. Throughout the remaining chapters, the emphasis is placed on patient and clinician safety through correct body mechanics, the application of assistive and safety devices, and the effective use of infection control procedures. Chapter 5 helps prepare the clinician for patient care. Chapter 6 describes the various methods by which a clinician can take a patient's vital signs and the significance of each of these vital signs. Chapter 7 covers the various methods to perform bed mobility skills, correctly drape and position a patient. Chapter 8 teaches the reader how to perform range of motion assessments and apply range of motion techniques as a treatment method. Chapter 9 describes the various methods to accurately test the strength of each of the patient's muscles. Chapter 10 describes wheelchair mobility skills and the various methods by which the clinician or clinical team can transfer a patient from and to various surfaces. Chapter 11 details the various components and parameters of gait and how to train a patient to ambulate with or without an assistive device. Finally, chapter 12 attempts to put all of the information together by providing a patient example"-- Provided by publisher.

    Contents:
    The physical therapy profession
    Healthcare regulations
    Evidence informed practice and clinical decision-making
    Clinical documentation
    Preparation for patient care
    Taking vital signs
    Bed mobility, patient positioning, and draping
    Mobility and range of motion
    Manual muscle testing
    Patient transfers and wheelchair mobility
    Gait training
    Putting it all together.
    Digital Access AccessPhysiotherapy 2022
  • Digital
    Mark Dutton, PT, Allegheny General Hospital, West Penn Allegheny Health System (WPAHS), Adjunct Clinical Instructor, Duquesne University, School of Health Sciences, Pittsburgh, Pennsylvania.
    Summary: Dutton's Orthopaedic Examination, Evaluation and Intervention provides readers with a systematic logical approach to the evaluation and intervention of the orthopedic patient. In this comprehensive and up-to-date fourth edition, Dutton strikes the perfect balance in its coverage of examination and treatment. The textbook emphasizes the appropriate use of manual techniques and therapeutic exercise while outlining the correct applications of electrotherapeutic and thermal modalities as adjuncts to the rehabilitative process.

    Contents:
    Anatomy
    Examination and evaluation
    Intervention
    The extremities
    The spine and TMJ
    Special considerations.
    Digital Access AccessPhysiotherapy 2017
  • Digital
    Mark Dutton.
    Summary: "This book aims to provide the reader with a systematic and evidence-based approach to the examination and intervention of the orthopaedic patient from the viewpoint of an expert on the movement system"-- Provided by publisher.

    Contents:
    The Musculoskeletal system
    Tissue behavior, injury, healing, and treatment
    The nervous system
    Patient/client management
    Differential diagnosis
    Gait and posture analysis
    Imaging studies in orthopaedics
    The intervention
    Pharmacology for the orthopaedic physical therapist
    Manual techniques
    Neurodynamic mobility and mobilizations
    Improving muscle performance
    Improving mobility
    Improving neuromuscular control
    Improving cardiovascular endurance
    The Shoulder
    Elbow
    The forearm, wrist, and hand
    Hip
    The knee
    Lower leg, ankle, and foot
    Vertebral column
    The craniovertebral region
    Vertebral artery
    The cervical spine
    The temporomandibular joint
    The thoracic spine
    Lumbar Spine
    The sacroiliac joint
    Special populations.
    Digital Access AccessPhysiotherapy 2020
  • Print
    Mark Dutton.
    Summary: "This book aims to provide the reader with a systematic and evidence-based approach to the examination and intervention of the orthopaedic patient as an expert on the movement system"-- Provided by publisher.
    Digital Access AccessPhysiotherapy 2023
  • Digital
    Mathias Baehr, Michael Frotscher.
    Summary: "The sixth edition of Duus' classic Topical Diagnosis in Neurology builds on the clear, integrated presentation of anatomy, function, and disorders of the central nervous system that made it a success for almost over five decades, serving as a quick reference for practitioners and trainees alike. It elucidates the neuroanatomical pathways that lead to specific clinical syndromes, and demonstrates how comprehensive anatomical knowledge combined with a thorough neurological examination can help localize and categorize a lesion and arrive at a differential diagnosis. The time-tested logical, thematic structure with useful summaries, at the beginning of each chapter, and color-coded section headings enable readers to distinguish neuroanatomical from clinical material at a glance and enable efficient and time saving study. Features of the sixth edition: - New tables and clinical case examples - Improved descriptions of neuroanatomical/neurophysiological basics in the context of clinical symptoms - Twenty-three new illustrations, to a total of more than 400 illustrations - A wide range of study aids and clinical correlations that support the emphasis on integrative medicine in the current medical school curricula Topical Diagnosis in Neurology is an ideal reference for neurologists and neuroscientists who correlate neurological diseases with anatomical location to arrive at a diagnosis or understand a clinical syndrome. It is also an essential tool for trainees and advanced students who need a solid grounding in key neurofunctional relationships"--Provided by publisher.
  • Digital
    Angelo A. Licata, Susan E. Williams.
    Summary: Dual-energy X-ray absorptiometry (DXA) is the principal x-ray technology used to diagnose osteoporosis in its early, asymptomatic stages, to assess treatment efficacy, and to guide treatment decisions. It remains the gold standard today. A DXA Primer for the Practicing Clinician: A Case-Based Manual for Understanding and Interpreting Bone Densitometry is based on actual clinical encounters and treatment dilemmas encountered by the authors. The content is derived from years of clinical practice and presentations given by the authors at regional and national conferences. It exemplifies not only the complete body of knowledge provided through these lectures but also the full range of previously undiscussed nuances of DXA interpretation. This practical, easy-to-read text captures many of the common challenges of DXA interpretation that clinicians often encounter. The central focus of the book is the presentation of what is normal and what is problematic when using DXA. It presents real-life case histories, their corresponding DXA images, the problems encountered and their solutions. Unique in approach and presentation, this one-of-a-kind case-based manual will be of immense value to all clinicians and students motivated to optimize their diagnostic skills and assessment of patients with abnormal bone densities

    Contents:
    Introduction - How does one go from bone mineral density measurements to a diagnosis of osteoporosis
    What Is Osteoporosis?
    What Happens After I Order a DXA?
    What Is FRAX®?-- The DXA Report: What Every Referring Clinician Needs to Know
    Technological Errors in DXA Scanning: Common Errors in Diagnosing and Monitoring
    Monitoring Treatment Efficacy: DXA Pearls and Pitfalls
    Special Considerations in Common GI Diseases, Obesity, and Following Bariatric Surgery
    UFOs: Unexpected Foreign Objects
    Challenging Cases.
    Digital Access Springer 2014
  • Digital
    Kathleen D. Sanford, DBA, RN, CENP, FACHE, Senior Vice President and Chief Nursing Officer, Catholic Health Initiatives, Englewood, Colorado, Stephen L. Moore, MD, Senior Vice President and Chief Medical Officer, Catholic Health Initiatives, Englewood, Colorado.
    Summary: "Healthcare leaders are facing major change in how healthcare is delivered as we move from fee-for-service payment models to pay for value. Physicians and hospitals are evolving from separate financial entities (with relationships varying from customers/workshops to competitors) to unified systems. Government policy maker, payers, and hordes of consultants advise hospitals to increase physician leadership in all parts of the system. However, few have proposed how this can be done when the gaps between hospitals and physicians are so wide. Physicians do not trust healthcare leaders, lack leadership and teamwork skills, and have little knowledge of how systems work. Some hospital leaders are working to overcome these gaps by setting up dyad leadership teams, consisting of a physician and an experienced manager/leader. The physician member of the team helps with the first gap; the nurse or other dyad partner is important to manage the other gaps. Until now, with the publication of Dyad Clinical Leadership, there has not been a source to help clinical dyad partners learn and understand how to work together in this emerging management model. Kathleen D. Sanford, DBA, RN, CENP, FACHE, Senior Vice President and Chief Nursing Officer at Catholic Health Initiatives (CHI), builds on CHI's success with this unique playbook for the model"--Provided by publisher.

    Contents:
    Chapter 1. An introduction to a new leadership model
    Chapter 2. How did we get here and what do we need to get out of here?
    Chapter 3. Developing a dyad
    Chapter 4. Power, persuasion, politics, and perceptions
    Chapter 5. Culture shock: dyads as both harbingers and architects of cultural change
    Chapter 6. Dyads as catalysts for renewing the strength of the leadership team
    Chapter 7. Learning dyad skills
    Chapter 8. What do you believe?
    Chapter 9. Forming dyad-led teams and multiple partnerships
    Chapter 10. What we say today may not be true tomorrow.
    Digital Access Ovid 2015
  • Digital
    Lawrence Berk, editor.
    Contents:
    Art of dying / Lawrence Berk
    Dying: what happens in the cells and tissues / Lawrence Berk
    Dying: what happens to the body after death / Vernard Adams
    Quality of life at the end of life / Lodovico Balducci and Miriam Innocenti
    Legal aspects of oncology care for dying patients / Marshall B. Knapp
    Spiritual care: an essential aspect of cancer care / Kenneth J. Doka
    Religious views of the afterlife / Christopher M. Moreman
    A historical perspective of death in the western world / David San Filippo
    Economic aspects of death and dying in oncology / Vlad Dolgopolov
    Oncologists and death / Lawrence Berk
    Pediatric cancer and end-of-life / Kathleen G. Davis
    Symptom management of the dying oncology patient / Lawrence Berk.
    Digital Access Springer 2017
  • Print
    Jeffrey Pfeffer.
    Summary: "In this timely, provocative book, Jeffrey Pfeffer contends that many modern management commonalities such as long hours, work-family conflict, and economic insecurity are toxic to employees--hurting engagement, increasing turnover, and destroying people's physical and emotional health--while also being inimical to company performance. He argues that human sustainability should be as important as environmental stewardship. You don't have to do a physically dangerous job to confront a health-destroying, possibly life-threatening workplace ... In "Dying for a Paycheck", Jeffrey Pfeffer marshals a vast trove of evidence and numerous examples from all over the world to expose the infuriating truth about modern work life: even as organizations allow management practices that actually sicken and kill their employees, those policies do not enhance productivity or the bottom line, thereby creating a lose-lose situation. Exploring a range of important topics, including layoffs, health insurance, work-family conflict, work hours, job autonomy, and why people remain in toxic environments, Pfeffer offers guidance and practical solutions that all of us--employees, employers, and the government--can use to enhance workplace well-being. We must wake up to the dangers and enormous costs to today's workplace, Pfeffer argues. "Dying for a Paycheck" is a clarion call for a social movement focused on human sustainability. Pfeffer makes clear that the environment we work in is just as important as the one we live in, and with this urgent book he opens our eyes and shows how we can make our workplaces healthier and better."--Jacket flaps.

    Contents:
    Introduction
    Management decisions and human sustainability
    The enormous toll of toxic workplaces
    Layoffs and economic insecurity : a lose-lose proposition
    No health insurance, no health
    Health effects of long work hours and work-family conflict
    Two critical elements of a healthy workplace
    Why people stay in toxic workplaces
    What might--and should--be different.
    Print Access Request
    Location
    Version
    Call Number
    Items
    BioSciences Career Center Collection (Duck Room)
    Bus & Mgt 106
    1
  • Digital/Print
    Jonathan M. Metzl.
    Summary: A physician reveals how right-wing backlash policies have mortal consequences-even for the white voters they promise to help Named one of the most anticipated books of 2019 by Esquire and the Boston Globe In the era of Donald Trump, many lower- and middle-class white Americans are drawn to politicians who pledge to make their lives great again. But as Dying of Whiteness shows, the policies that result actually place white Americans at ever-greater risk of sickness and death. Physician Jonathan M. Metzl's quest to understand the health implications of "backlash governance" leads him across America's heartland. Interviewing a range of everyday Americans, he examines how racial resentment has fueled progun laws in Missouri, resistance to the Affordable Care Act in Tennessee, and cuts to schools and social services in Kansas. And he shows these policies' costs: increasing deaths by gun suicide, falling life expectancies, and rising dropout rates. White Americans, Metzl argues, must reject the racial hierarchies that promise to aid them but in fact lead our nation to demise.

    Contents:
    Introduction: dying of whiteness
    Part I: Missouri: The cape
    Risk
    Interview: I can't just make it go away
    The man card
    Interview: we gotta take up arms
    Preventative medicine
    Interview: the biggest heart
    What was the risk?
    Interview: the whys and what-ifs
    Trigger warnings
    Part 2: Tennessee: Unaffordable
    Cost
    In the name of affordable care
    Focus
    Socialism
    Everybody
    De-progressive
    The numbers tell the story
    Part 3: Kansas: Beneath the surface
    There's no place like home
    The Kansas experiment
    Interview: a downward cycle
    Austerity
    Interview: a bad rap
    The schools
    Interview: the race card
    Congestive heart failure
    Interview: no matter what he does
    Millions of millions
    Conclusion: the castle doctrine
    Notes
    Index.
    Digital Access EBSCO 2019
    Limited to 1 simultaneous user
    Print Access Request
    Location
    Version
    Call Number
    Items
    RA563.M56 M48 2019
    1
  • Print
    edited by Avivah Zuckerman and David W. Weiss.
    Print Access Request
    Location
    Version
    Call Number
    Items
    Stored offsite. Please request print.
    QL757 .D96
    2
  • Digital
    Jeffrey N. Weiss.
    Summary: Blindness or serious vision impairment is one of the most feared disabilities known to humankind. A 2016 report compiled by the National Eye Institute (NEI) of the National Institutes of Health (NIH) and Prevent Blindness America states that although half of all blindness can be prevented, the number of people who suffer vision loss continues to increase. The technique of dynamic light scattering (DLS) was developed by physicists in the late 1960s to early 1970s. DLS is now emerging as a potential ophthalmic tool, making possible studies of virtually every tissue and fluid comprising the eye, thus pushing the envelope for broader applications in ophthalmology. This book presents a comprehensive review of the application of light scattering in clinical use. It is the first of its kind, offering insight to how DLS can be applied to the human eye as well as animals. Chapters discuss DLS in neurological diseases, including protocols, informed consent, and patents. Dynamic Light Scattering Spectroscopy of the Human Eye is a must-have resource for physicians, engineers, and physicists interested in the clinical application of DLS to diagnose and potentially treat medical conditions in a non-invasive, quantitative and novel way. .

    Contents:
    Chapter 1. Anatomy of the eye
    Chapter 2. Light Scattering
    Chapter 3. Dynamic Light Scattering (DLS)
    Chapter 4. DLS Animal Experiments
    Chapter 5. DLS Human Experiments
    Chapter 6. DLS in Neurologic diseases - Protocol
    Chapter 7. DLS in Neurologic diseases Informed Consent
    Chapter 8. Patents. .
    Digital Access Springer 2022
  • Digital
    [edited by] Daniel H. Kim, MD, FAANS, FACS, Professor, Director of Spinal Surgery, Reconstructive Peripheral Nerve Surgery, Department of Neurosurgery, Memorial Hermann, the University of Texas Health Science Center at Houston, Houston, Texas, Dilip K. Sengupta, MD, DrMed, Director, Clinical Research, Attending Spine Surgeon, Texas Back Institute, Plano, Texas, Frank P. Cammisa Jr., MD, FACS, Chief, Spinal Surgical Service, Attending Surgeon, Spine Care Institute, Hospital for Special Surgery, Professor of Orthopedic Surgery, Weill Medical College of Cornell University, New York, New York, Do Heum Yoon, MD, PhD, Professor, Department of Neurosurgery, Yonsei University College of Medicine, Seoul, Republic of Korea, Richard G. Fessler, MD, PhD, Professor, Department of Neurological Surgery, Rush University College of Medicine, Chicago, Illinois.
    Summary: "Dynamic Reconstruction of the Spine, Second Edition, is an up-to-date, comprehensive resource on the instrumentation, technologies, and fundamental science integral to achieving spine motion preservation and stabilization. This revised text covers not only the latest technologies and surgical approaches, including MIS techniques, but also significantly more detail on the clinical biomechanics of the spine than the previous edition. Readers will appreciate the guidance this book provides on how to: successfully adopt new technology, find appropriate indications, address common safety and efficacy issues, and answer health economics questions for ethics committees and payers. Key Features: A substantial revision, with entirely new chapters in three quarters of the book, including a large section on basic as well as more advanced biomechanics topics. Highly visual - contains 20% more figures than the previous edition. Discusses and explains current advances in genetic and molecular technologies used to repair the spinal disc Includes an unbiased critique of the pro cons, clinical outcomes, and comparative outcomes of different devices. This new edition is an indispensable reference for orthopedic surgeons, neurosurgeons, and radiologists, as well as residents and fellows seeking the latest information on the technologies used in spine motion preservation and stabilization"-- Provided by publisher.
  • Digital
    Pallaval Veera Bramhachari, editor.
    Summary: This book discusses various components of the innate and adaptive immune response in combating viral infections, presenting the recent advances in our understanding of innate immunity recognition of viruses and highlighting the important role of inflammation, cytokines such as interferon, toll-like receptors and leukocytes in the initial detection of invading viruses and subsequent activation of adaptive immunity. It also summarizes the role of the adaptive immunity against viral infections through clearance of virus and establishment of memory response that protects against the recurrent infections. In addition, the book examines the role of DNA and RNA sensors in viral recognition and in controlling viral infection. Lastly, it reviews the latest developments in the development of the rational viral vaccines. As such it is a useful resource book for postgraduate and early researchers wanting to gain insights into the immune response to viral infections.

    Contents:
    Chapter 1. Significance and dynamics of immune responses during viral pathogenesis
    Chapter 2. Antibody-dependent enhancement of viral infections
    Chapter 3. Inflammation during virus infection: swings and roundabouts
    Chapter 4. Interferons and their role in Viral infection
    Chapter 5. Role of Cytokines in combating viral infections: Siginificance and relevance
    Chapter 6. B cells and their role in combating viral diseases
    Chapter 7. Significant role of Cellular activation in viral infections Bojjibabu Chidipi1 Samuel Ignatious Bolleddu, Ganugula Mohana Sheela and Alavala Mattareddy
    Chapter 8. Macrophages/Micro vesicles and their task in viral diseases Macrophages/Microvesicles and their task in viral diseases
    Chapter 9. T cells in viral infections: The myriad flavours of antiviral immunity
    Chapter 10. Potentiality of Toll Like Receptors (TLRs) in viral infections
    Chapter 11. Activation and immune evasion of viruses from Complement system
    Chapter 12. microRNAs and their role in viral infection
    Chapter 13. Evolution, Distribution and Diversity of Immunodeficiency Viruses
    Chapter 14. Role of immune cells in Hepatitis B infection
    Chapter 15. Role of RNA Sensors in Immunity against Viral Diseases
    Chapter 16. Role of DNA Sensors in Immunity against Viral Diseases
    Chapter 17. Advanced immunotechnological methods for detection and diagnosis of viral infections: Current applications and future challenges
    Chapter 18. Current advances in viral vaccines development and Research.
    Digital Access Springer 2020
  • Digital
    [edited by] Merle Myerson.
    Summary: "Dyslipidemia: A Clinical Approach is intended as a low-cost, quick-reference, easy-to-navigate guide for a broad range of healthcare professionals that will provide high-yield decision-making tools to ensure confidence in patient treatment and management of those who are suffering from a lipids disorder or related disease. Content will include detailed drug tables, information on important drug interactions, and also non-statin alternatives for those patients who cannot tolerate statins. In addition, decision-making algorithms and careful patient management plans will be included to ensure quicker and more effective treatment and management of patients"--Provided by publisher.

    Contents:
    1. A historical perspectives on lipids and cardiovascular disease
    2. Basic lipid and lipoprotein biochemistry for clinical lipidologists
    3. Guidelines and risk scores
    4. Lipid measurement
    5. Step-by-step diagnosis and management plan
    6. Lifestyle modification in the management of dyslipidemia
    7. Lipid medications overview: prescription and nonprescription preparations
    8. Statins
    9. Nonstain medications: omega-3 fatty acids, fibrates, bile acid sequestrants, niacin, and cholesterol absorption inhibitors
    10. Hypertriglyceridemia
    11. Safety and tolerability of lipid-lowering medications
    12. Familial hypercholesterolemia: family disease
    13. Complex dyslipidemias
    14. Children and adolescents step-by-step evaluation and management plan
    15. Lipid management in special populations.
    Digital Access Ovid 2019
  • Digital
    Abhimanyu Garg.
    Summary: Dyslipidemias: Pathophysiology, Evaluation and Management provides a wealth of general and detailed guidelines for the clinical evaluation and management of lipid disorders in adults and children. Covering the full range of common through rare lipid disorders, this timely resource offers targeted, practical information for all clinicians who care for patients with dyslipidemias, including general internists, pediatric and adult endocrinologists, pediatricians, lipidologists, cardiologists, internists, and geneticists. For the last twenty years, there has been a growing recognition worldwide of the importance of managing dyslipidemia for the primary and secondary prevention of atherosclerotic vascular disease, especially coronary heart disease. This has been mainly due to the publication of the guidelines of National Cholesterol Education Programs Adult Treatment Panel and Pediatric Panel from the United States. These guidelines have stimulated generation of similar recommendations from all over the world, particularly Europe, Canada, Australia and Asia. Developed by a renowned group of leading international experts, the book offers state-of-the-art chapters that are peer-reviewed and represent a comprehensive assessment of the field. A major addition to the literature, Dyslipidemias: Pathophysiology, Evaluation and Management is a gold-standard level reference for all clinicians who are challenged to provide the best care and new opportunities for patients with dyslipidemias.

    Contents:
    Lipoprotein Physiology
    Epidemiology of Blood Lipids and Lipoproteins
    Lipoprotein(a)
    Lipoproteins and Cardiovascular Disease Risk
    Detection and Treatment of Children and Adolescents with Dyslipidemia
    Type 2 Diabetes Mellitus and Dyslipidemia
    Type 1 Diabetes Mellitus and Dyslipidemia
    Dyslipidemia in Chronic Kidney Disease and Nephrotic Syndrome
    Dyslipidemia in HIV-infected Patients
    Monogenic Hypercholesterolemia
    Primary Hypertriglyceridemia
    Genetic Disorders of HDL Metabolism
    Sitosterolemia and Other Rare Sterol Disorders
    Genetic Abetalipoproteinemia & Hypobetalipoproteinemia
    Drug-induced Dyslipidemia
    Lipodystrophies and Dyslipidemias
    Novel Genes for Dyslipidemias: Genome-Wide Association Studies
    Perspectives on Cholesterol Guidelines
    Nutrition and Coronary Heart Disease Prevention
    Phytosterol Therapy
    N-3 Fatty Acids: Role in Treating Dyslipidemias and Preventing Cardiovascular Disease
    Polyphenols for Cholesterol Management
    Dietary Supplements for Cholesterol Management
    Statins: Risk-Benefits and Role in Treating Dyslipidemias
    Fibrates: Risk-Benefits and Role in Treating Dyslipidemias
    Niacin: Risk-Benefits and Role in Treating Dyslipidemias
    Bile Acid Sequestrants: Risk-Benefits and Role in Treating Dyslipidemias
    Cholesterol Absorption Inhibitor-Ezetimibe: Risk-Benefits and Role in Treating Dyslipidemias
    Low Density Lipoprotein (LDL) Apheresis
    Novel Lipid Lowering Agents.
    Digital Access Springer 2015
  • Digital
    edited by Adrian Covic, Mehmet Kanbay, Edgar V. Lerma.
    Digital Access Springer 2014
  • Digital
    Roger P. Smith.
    Summary: Dysmenorrhea is estimated to effect upwards of 70% of women during their lifetime and heavy menstrual periodsis one of the most frequently given reasons for hysterectomy in the United States. Despite the dramatic growth of dysmenorrhea treatment with non-steroidal anti-inflammatory agents (NSADs) in the 1980s, young women continue to go undiagnosed and under treated. The diagnosis and management of heavy menstrual bleeding has even poorer general understanding because of its more complicated etiologies. With a working knowledge of the underlying pathophysiology, all clinicians should be able to establish both the diagnosis and a credible treatment plan that will result in a significant chance of clinical improvement for most patients. This book addresses the pathophysiologic underpinnings of both dysmenorrhea and menorrhagia and provides clinicians with practical approaches to establishing the diagnosis, proven tactics for successful therapeutic interventions and dealing with the challenging atypical case, and effective patient counseling. It teaches principles, including the role prostaglandins play in both conditions, as well as procedures, like surgical options and TENS, providing a balance of the practical and the esoteric. The inclusion of patient education and counseling materials additionally increases its usefulness for the busy clinician. This is an ideal guide for ob/gyn clinicians, residents, and trainees caring for patients with these common, but often misunderstood diseases.
    Digital Access Springer 2018
  • Digital
    Krishnakumar Thankappan, Subramania Iyer, Jayakumar R Menon, editors.
    Digital Access Springer 2018
  • Digital
    editors, Alfonso Fasano, Francesca Morgante.
    Contents:
    Dystonia : a clinician's guide to diagnosis, pathophysiology and treatment / Alfonso Fasano & Francesca Morgante
    Symptoms of dystonia / Alfonso Fasano, Sophie Lehnerer & Antonio Emanuele Elia
    Pathophysiology of dystonia / Francesca Morgante
    Classification of dystonia / Nardo Nardocci & Giovanna Zorzi
    Genetics of dystonia / Toshitaka Kawarai & Ryuji Kaji
    Medication for dystonia / Christoph Kamm
    Surgical treatment of dystonia / Wolfgang Fogel & Wolfgang Jost
    Physical management of dystonia / Roongroj Bhidayasiri.
    Digital Access Future Med 2014
  • Digital
    Petr Kanovsky, Kailash P. Bhatia, Raymond L. Rosales, editors.
    Contents:
    Part I. Pathophysiology and nosology of dystonia
    Dystonia: History of the term and syndrome
    Physiology of dystonia
    Genetics of dystonia
    Nosology and classification of dystonia
    Secondary dystonias
    Dystonia
    parkinsonism syndromes
    Dystonia in multiple system atrophy and progressive supranuclear palsy
    Psychogenic dystonia
    Part II. Treatment of dystonia
    Pharmacological treatment of dystonia
    Botulinum toxin treatment of dystonia
    Long-term BoNT treatment of dystonia
    Brain plasticity in dystonia
    Surgical treatment of dystonia
    Indications of deep brain stimulation in dystonia
    Pitfalls of deep brain stimulation in dystonia
    Neurorehabilitation in dystonia
    Dystonia in Art: The Impact of Psychiatric and Neurological Disease on the Work of the Sculptor F.X. Messerschmidt.
    Digital Access Springer 2015

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Derived from Current Medical Diagnosis & Treatment, AccessMedicine's Quick Medical Diagnosis & Treatment provides topic reviews with key diagnostic and treatment features for more than 500 diseases.

A repository of medical knowledge from internal medicine, cardiology, genetics, pharmacy, diagnosis and management, basic sciences, patient care, and more.

Continuously expanding, all databases in the repository contain the latest editions of selected medical titles.

MicroMedex: Premier pharmaceutical information source containing multiple databases and drug reference tools. Of particular value is DRUGDEX Evaluations, one of the most comprehensive drug sources available. DynaMed is a clinical information resource used to answer questions quickly at the point-of-care. Easy-to-interpret Levels of Evidence help clinicians rapidly determine the quality of the available evidence.

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Large number of high quality software and database programming titles from O'Reilly. Other software titles are also available from Sams and Prentice Hall. Limited to 7 concurrent users. Includes peer-reviewed life science and biomedical research protocols compiled from Methods in Molecular Biology, Methods in Molecular Medicine, Methods in Biotechnology, Methods in Pharmacology and Toxicology, Neuromethods, the Biomethods Handbook, the Proteomics Handbook, and Springer Laboratory Manuals. Contains full text access to selected biomedical and nursing books.

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