BookJeanette Erdmann, Alessandra Moretti, editors.
Summary: This book provides a comprehensive summary of the latest developments in the field of the genomics of cardiac disease. Written and edited by leading clinicians and scientists involved in the analysis and therapy of genetic cardiac disorders, it discusses the genetic causes of a variety of cardiac diseases, such as the complex genetics and etiology of congenital heart diseases. It also explores sex differences in prevalent diseases, genetics-based therapeutic strategies and the use of various animal models and alternatives. The book is intended for research scientists and clinical scientists in the cardiovascular field, human geneticists and cardiologists.
Contents:
Genetics of adult and fetal forms of Long QT Syndrome
The genetic landscape of cardiomyopathies. Genetic basis of mitochondrial cardiomyopathy
The Genetics of Coronary Heart Disease
Complex genetics and the etiology of human congenital heart disease-Familial Hypercholesterolemia
Long non-codingRNAs in cardiovascular disease
Mouse models to study inherited cardiomyopathy
Interrogating cardiovascular genetics in zebrafish
Human induced pluripotent stem cells as a platform for functional examination of cardiovascular genetics in a dish
Systems medicine as a transforming tool for cardiovascular genetics
Sex differences in prevalent cardiovascular disease in the general population.