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  • Book
    J. Rick Turner, Dilip R. Karnad, Snehal Kothari.
    Contents:
    The Central Importance of Cardiovascular Safety in Contemporary New Drug Development
    The Biological Basis of Drug Responses
    Cardiovascular Structure, Function, Pathophysiology, & Disease
    The Current Regulatory Landscape
    The "Comprehensive In Vitro Proarrhythmia Assay" Initiative
    The "Early ECG Assessment" Initiative
    The "Submission of Extended Digital ECG Data" Initiative
    Meta-analysis and Meta-methodology
    Current Regulatory Landscapes and their Potential Evolution
    Off-target Blood Pressure Responses to Non-cardiovascular Drugs
    Oncology Drug Development and Therapeutics: Cardiotoxicity Considerations
    Postmarketing Surveillance
    Regulatory Perspectives on General Drug Safety
    Future Directions in Cardiovascular Safety
    References.
    Digital Access Springer 2017