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  • Book
    Juan A. Rosado, editor.
    Digital : Springer2016
    Print2016
    Historical overview of store-operated Ca2+ entry -- The STIM1- Orai interaction -- The TRPCs, Orais and STIMs in ER/PM junctions -- The TRP-Na-Ca2+ exchanger coupling -- Role of TRPC channels in store-operated calcium entry -- Phospholipase A2 as a molecular determinant of store-operated calcium entry -- Extracellular calcium has multiple targets to control cell proliferation -- Regulation of platelet function by Orai, STIM and TRP -- On the roles of the Transient Receptor Potential Canonical 3 (TRPC3) channel in endothelium and macrophages: implications in atherosclerosis -- Second messenger-operated calcium entry through TRPC6 -- Transient Receptor Potential Canonical 7 (TRPC7), a Calcium (Ca2+) Permeable Nonselective Cation Channel -- Calcium entry through thermosensory channels -- Calcium signalling through ligand-gated ion channels such as P2X1 receptors in the platelet and other non-excitable cells -- The calcium entry-calcium refilling coupling -- Microdomains associated to lipid rafts -- Role of scaffolding proteins in the regulation of TRPC-dependent calcium entry -- Modulation of calcium entry by mitochondria -- Modulation of calcium entry by the endo-lysosomal system -- Remodeling of calcium entry pathways in cancer.