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  • Book
    Ian M.C. Dixon, Jeffrey T. Wigle, editors.
    Digital : Springer2015
    Cardiac fibrosis and heart failure-- cause or effect? -- Fibroblast activation in the infarcted myocardium -- Mechanical and matrix regulation of valvular fibrosis -- Bone marrow-derived progenitor cells, micro-RNA, and fibrosis -- The stressful life of cardiac myofibroblasts -- Pathogenic origins of fibrosis in the hypertensive heart disease that accompnaies aldosternoism -- Embryological origin of valve progenitor cells -- Diverse cellular origin of valve progenitor cells -- Diverse cellular origins of cardiac fibroblasts -- Non-canonical regulation of TGF-β1 signaling: a role for Ski/Sno and YAP/TAZ -- Molecular mechanisms of smooth muscle and fibroblast phenotype conversions in the failing heart -- Current and future strategies for the diagnosis and treatment of cardiac fibrosis -- Remodelling of the cardiac extracellular matrix: role of collagen degradation and accumulation in pathogenesis of heart failure -- Matrix metalloproteinase 9 (MMP-9) -- Collagen processing and its role in fibrosis -- Mechanisms of cardiac fibrosis and heart failure -- Mathematical simulations of sphingosine-1-phosphate actions on mammalian ventricular myofibroblasts and myocytes -- Extracellular matrix and cardiac disease: surgical and scientific perspectives -- The role or neurohumoral activation in cardiac fibrosis and heart failure -- Natriuretic peptides: critical regulators of cardiac fibroblasts and the extracellular matrix in the heart -- Cardiac tissue engineering for the treatment of heart failure post-infarction -- Mechanisms in cardiac valve failure and the development of tissue engineered heart valves -- Index.